Sleep Apnea, Central clinical trials
The registry lists 96 studies for Sleep Apnea, Central across more than 10 countries. 18 are recruiting or about to start. 47 of them are mainly about Sleep Apnea, Central (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-06.
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Who runs them
ResMed (8) · VA Office of Research and Development (5) · Philips Respironics (5) · Respicardia, Inc. (5) · Assistance Publique - Hôpitaux de Paris (4) · The Hospital for Sick Children (4) · Philips Clinical & Medical Affairs Global (3) · Universitaire Ziekenhuizen KU Leuven (2)
What is being tested here
Drugs under test in Sleep Apnea, Central studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5
- Dec 2026Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep Apnea · Shionogi
- Dec 2026Central Sleep Apnea : Physiologic Mechanisms to Inform Treatment · VA Office of Research and Development
- Mar 2027Development of a Torso Patch Sensor (C-TraQ) as a Companion Device to a Fingertip Sensor (TipTraQ) for Direct Monitoring of Respiratory Effort · PranaQ Pte. Ltd.
- Jul 2027Automated Apnoea Detection in Preterms on Non-invasive Ventilation · King's College Hospital NHS Trust
- Nov 2027Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome) · Assistance Publique - Hôpitaux de Paris
Who these studies take
Of the 13 Sleep Apnea, Central studies recruiting now, 8 (62%) set no upper age limit and 3 (23%) stop at 75 or younger. 4 (31%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 5 (38%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (31%) | 4 (31%) |
| 18 | 12 (92%) | 12 (92%) |
| 30 | 11 (85%) | 11 (85%) |
| 40 | 11 (85%) | 11 (85%) |
| 50 | 11 (85%) | 11 (85%) |
| 65 | 11 (85%) | 11 (85%) |
| 75 | 11 (85%) | 11 (85%) |
| 85 | 10 (77%) | 10 (77%) |
Across all 96 studies, recruiting or not: 20% stop at 75 or younger and 10% at 65; 17% take children; 1% are for women only and 3% for men only; 21% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Sleep Apnea, Central studies take
Of 18 observational studies under Sleep Apnea, Central, half reached primary completion within 57 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 22 mo9–67 · 14 studies | — | — |
| Observational | 57 mo25–107 · 18 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting2
- Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome)Nov 6, 2026NCT07081464
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform TreatmentOct 13, 2026NCT07210606
Newly registered2
- Supplemental Oxygen for Sleep-Disordered Breathing in Adults With Chronic Opioid Use.Nov 6, 2026NCT07923760
- Registry of Central Sleep Apnea Patients Undergoing remedē System ImplantOct 30, 2026NCT07907068
Studies
Recruiting first, then most recently updated. Showing 50 of 96. Browse all 96 → or search them.
- Supplemental Oxygen for Sleep-Disordered Breathing in Adults With Chronic Opioid Use.Not yet recruitingNCT07923760Phase 21 country
- Locus Coeruleus and CCHS (Congenital Central Hypoventilation Syndrome)RecruitingNCT070814641 country
- Registry of Central Sleep Apnea Patients Undergoing remedē System ImplantNot yet recruitingNCT07907068
- Central Apnea in Heart Failure: Physiological Mechanisms to Inform TreatmentRecruitingNCT07210606Phase 41 country
- PAH-SDB: Sleep-Disordered Breathing and Outcomes in Pulmonary Arterial HypertensionRecruitingNCT078524031 country
- Neurocognition in Congenital Central Hypoventilation Syndrome (CCHS)RecruitingNCT035686691 country
- Automated Apnoea Detection in Preterms on Non-invasive VentilationNot yet recruitingNCT07794007
- Development of a Torso Patch Sensor (C-TraQ) as a Companion Device to a Fingertip Sensor (TipTraQ) for Direct Monitoring of Respiratory EffortRecruitingNCT077448541 country
- Central Sleep Apnea : Physiologic Mechanisms to Inform TreatmentRecruitingNCT04118387Phase 41 country
- Natural History of Central and Mixed Sleep Apneas Followed by Maxillomandibular Advancement for Obstructive Sleep ApneaNot yet recruitingNCT075967191 country
- Impact of Transcatheter Aortic Valve Implantation and Mitral Valve Repair on Sleep-Disordered BreathingRecruitingNCT075206561 country
- Assessing the Performance of Wesper Lab for Obstructive and Central Sleep ApneaNot yet recruitingNCT07095413Not applicable
- Sleep Disordered Breathing and Multimorbidity: The Xiangya SDB Cohort StudyRecruitingNCT067558401 country
- Apnea, Stroke and Incident Cardiovascular EventsRecruitingNCT043992001 country
- Belgian Central Sleep Apnea REgistryRecruitingNCT036215661 country
- Interface Selection for Adaptive Servo VentilationRecruitingNCT02919930Not applicable1 country
- Relationship Between Breathing and Attention in Children With Ondine SyndromeRecruitingNCT063371491 country
- A Study of Breathing Sound-based Classification of Patients With Breathing DisordersRecruitingNCT058686941 country
- remedē System Therapy StudyActive, not recruitingNCT038846602 countries
- Long-term Observation of PAP-therapy With Telemonitoring: Telemedicine Registry TelePAPCompletedNCT030437161 country
- Diagnosis of Sleep-Related Respiratory Disorders in Patients With Narcotic MedicationsCompletedNCT03670914Not applicable1 country
- Safety and Efficacy Study of Sivopixant, Acetazolamide and SASS-001 in Sleep ApneaActive, not recruitingNCT06776432Phase 21 country
- Quality of Sleep of Patients With Predominant Central Sleep Apnea Syndrome(SAS) Whose EF > 45% Treated by ASVCompletedNCT028356381 country
- Apnea and Insomnia Relief StudyCompletedNCT04007796Phase 21 country
- Managing Opioid Related Sleep Apnea With AcetazolamideCompletedNCT06043830Phase 21 country
- ASV Effects on Myocardial Energetics and Sympathetic Nerve Function in Heart Failure and Sleep Apnea.Active, not recruitingNCT02116140Not applicable1 country
- Cardiac Resynchronisation Therapy in Combination With Overdrive Pacing in the Treatment of Central Sleep Apnea in CHFCompletedNCT00551499Phase 41 country
- Oxygen Versus Medical Air for Treatment of CSA in Prader Will SyndromeCompletedNCT03031626Phase 41 country
- The IPAd Study: Exploring the Association Between Insomnia and Positive Airway Pressure Adherence in ChildrenCompletedNCT059491641 country
- Central Sleep Apnea Prevalence and Impact on Cognitive Function in Patients with Heart Failure with Reduced or Mildly Reduced Left Ventricular Ejection FractionCompletedNCT063138401 country
- CO2 Supplement for Treatment of Acute Mountain SicknessCompletedNCT06393998Not applicable1 country
- Registry on the Treatment of Central and Complex Sleep-Disordered Breathing With Adaptive Servo-VentilationCompletedNCT030320296 countries
- Heated Humidified High Flow Nasal Cannula Oxygen in Obstructive Sleep Apnea in AdolescentsCompletedNCT05354401Not applicable1 country
- Comparison of CPAP With SOMNOventCR in Patients With Underlying Heart Disease, Combined OSA and CSRCompletedNCT00811668Not applicable
- Different Loop Gain Phenotypes in Patients With Chronic Systolic Heart Failure and Periodic BreathingCompletedNCT035324121 country
- Sleep and Breathing in the General Population - Chemical StimuliCompletedNCT04720547Phase 41 country
- A Prospective Multicenter Registry of Patients With Sleep Disordered Breathing Treated With DreamStation BiPAP autoSV.CompletedNCT034217041 country
- The Impact of Low Flow Nocturnal Oxygen Therapy on Hospital Admissions and Mortality in Patients With Heart Failure and Central Sleep ApneaTerminatedNCT03745898Phase 31 country
- Pathophysiological Study of CSA in Adults With pLVEFTerminatedNCT03919344Not applicable1 country
- Arterial Oxygen Saturation on Ventilatory Stability in Extremely Premature InfantsCompletedNCT03695900Not applicable1 country
- Effects of Naltrexone on Nocturnal Breathing Patterns at AltitudeCompletedNCT05037032Phase 41 country
- Transcutaneous CO2 Monitoring at Home for Children With Neuromuscular DiseaseActive, not recruitingNCT03478566Not applicable1 country
- DreamKit Diagnostic ValidationCompletedNCT04671342Not applicable1 country
- DreamKit Respiratory Effort Signal ValidationCompletedNCT04926077Not applicable1 country
- Effect of Adaptive Servo Ventilation (ASV) on Survival and Hospital Admissions in Heart FailureTerminatedNCT01128816Not applicable9 countries
- Screening of OSA in Hospitalized Stroke Patients Using BSPStatus unknownNCT05466864Not applicable1 country
- Early Sleep Apnea Treatment in StrokeStatus unknownNCT02554487Not applicable4 countries
- Nocturnal Oxygen Needs and Central Sleep Apnea in Patients With Chronic Heart Failure.Status unknownNCT03254212Phase 41 country
- Central Sleep Apnea Treated by CO2 Supplied by a Novel DeviceCompletedNCT04907058Not applicable1 country
- Cognitive Consequences of an Activation of the Cortical Drive to Breath (VENTIPSY)CompletedNCT030957291 country