Scleroderma, Localized clinical trials
The registry lists 115 studies for Scleroderma, Localized across more than 10 countries. 16 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-09-24.
Status
- Completed
- 72
- Terminated
- 11
- Recruiting
- 10
- Status unknown
- 8
- Withdrawn
- 6
- Not yet recruiting
- 5
Phase
- Phase 2
- 25
- Phase 1
- 11
- Phase 3
- 9
- Early Phase 1
- 3
- Phase 4
- 2
Where
- United States
- 49
- Canada
- 12
- France
- 10
- Turkey
- 9
- United Kingdom
- 4
- Germany
- 3
Who runs them
Lady Davis Institute (6) · Duke University (4) · Johns Hopkins University (4) · Istanbul University (4) · University of Michigan (4) · University of Texas Southwestern Medical Center (4) · Hacettepe University (3) · Firat University (3)
Studies
Recruiting first, then most recently updated. Showing 50 of 115 — search for more.
- Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA RepositoryRecruitingNCT018089371 country
- Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With SclerodermaRecruitingNCT07292961Not applicable1 country
- Patients Diagnosed With Scleroderma: Physical Performance and FunctionalityRecruitingNCT071830721 country
- Patients Diagnosed With Scleroderma and Their Chewing and Swallowing PerformanceRecruitingNCT071829811 country
- UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in SclerodermaEnrolling by invitationNCT04875078Not applicable1 country
- Respiratory Muscle Training in SclerodermaNot yet recruitingNCT06684132Not applicable
- 6-minute Pegboard Ring Test in Patients with SclerodermaNot yet recruitingNCT065889591 country
- Respiratory Muscle Strength and Aerobic Capacity in SclerodermaRecruitingNCT065541321 country
- Connective Tissue Massage in SclerodermaRecruitingNCT06474910Not applicable1 country
- Subcutaneous Semaglutide in Systemic SclerodermaRecruitingNCT06149260Phase 11 country
- Delving Into Participation Trends of Scleroderma Clinical TrialsNot yet recruitingNCT062644921 country
- Rehabilitation Program in Patients With SclerodermaRecruitingNCT05041868Not applicable1 country
- Effectiveness of ESWT and PNF in Scleroderma With CalcinosisNot yet recruitingNCT05870852Not applicable
- Pilot Study of Description of Cicatrisation Rates of Digital Ulcers in Systemic SclerodermaRecruitingNCT043191201 country
- Lung Clearance Index to Identify Scleroderma Patients at Risk for ILDRecruitingNCT045352451 country
- ADRCs in The Treatment of Hand Dysfunction Due to SclerodermaNot yet recruitingNCT05148598Phase 3
- Study on the Efficacy of Autologous Fat Grafting in Improving Hair Transplantation Outcomes for Patients With Localized Scleroderma-Related AlopeciaCompletedNCT06646146Not applicable1 country
- Efficacy and Safety of Imatinib in SclerodermaCompletedNCT00479934Phase 21 country
- Photobiomodulation in Children With Localized SclerodermaCompletedNCT06621628Not applicable1 country
- Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin DiseasesActive, not recruitingNCT04922736Not applicable1 country
- A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease PatientsTerminatedNCT04837131Phase 21 country
- CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PHWithdrawnNCT03726398Phase 2/31 country
- Study on the Treatment With Water-filtered Infrared-A (wIRA) Radiation in Patients With Morphea and Sclerotic Graft-versus-host DiseaseTerminatedNCT04954573Not applicable1 country
- Phenotyping of Chronic Pain in Diffused Systemic SclerodermaCompletedNCT05622578Not applicable1 country
- Development and Evaluation of an Evidence-based Education Program for People With Hand Dysfunction in SclerodermaActive, not recruitingNCT06697561Not applicable1 country
- Clinical Trial to Evaluate Efficacy and Safety of Dupilumab in Localized SclerodermaCompletedNCT04200755Phase 21 country
- microRNAs in Systemic SclerodermaCompletedNCT041487161 country
- Effectiveness of the EmoLED Medical Device in the Healing of Digital Ulcers in Patients With Scleroderma.TerminatedNCT05181644Not applicable1 country
- Exercise With Scleroderma Functional OutcomesCompletedNCT06425653Not applicable1 country
- Treatment of Refractory Sever Systemic Scleroderma by Injection of Allogeneic Mesenchymal Stem CellsCompletedNCT02213705Phase 1/21 country
- Calcinosis in a Single-Center Scleroderma PopulationCompletedNCT020621251 country
- A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)TerminatedNCT03740724Phase 1/21 country
- Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil DiethanolamineCompletedNCT00775463Phase 23 countries
- Effects of FT011 in Systemic SclerosisCompletedNCT04647890Phase 25 countries
- Scleroderma Lung Study III - Combining Pirfenidone With MycophenolateCompletedNCT03221257Phase 21 country
- Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Patients With Systemic Sclerosis With Interstitial Lung DiseaseTerminatedNCT01559129Phase 210 countries
- RENEW Scleroderma: A Peer-Mentored, Web Intervention for Resilience-based, Energy Management to Enhance Wellbeing and FatigueCompletedNCT04908943Not applicable1 country
- Telerehabilitation on Hand-Affected SclerodermaCompletedNCT04684225Not applicable1 country
- Co-designing Digital Ulcers Opportunities With Patients and CliniciansStatus unknownNCT05785403
- Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together ProgramCompletedNCT04335279Not applicable1 country
- The Influence of Extracorporeal Photopheresis on Skin SclerosisCompletedNCT047523971 country
- Upper Extremity Home Exercises in Patients With SclerodermaCompletedNCT05080738Not applicable1 country
- Scleroderma RegistryCompletedNCT000745681 country
- The Scleroderma Biorepository and Pathogenesis Study (STOP Scleroderma)CompletedNCT028874951 country
- Novel Splinting Technique Using 3D ModelsStatus unknownNCT05351060Not applicable1 country
- Effectiveness of Telerehabilitation on SclerodermaStatus unknownNCT04563481Not applicable1 country
- Scleroderma Patient-centered Intervention Network (SPIN) Hand ProgramCompletedNCT03419208Not applicable1 country
- Clinical and Paraclinical Characteristics of the Systemic Scleroderma Cohort According to the Criteria ACR 2013 and the History of Professional Exposure or of Agricultural EnvironmentCompletedNCT032629221 country
- Novel Screening Strategies for Scleroderma PAHCompletedNCT019598151 country
- A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory SclerodermaStatus unknownNCT05085444Early Phase 11 country