Scleroderma, Localized clinical trials
The registry lists 27 studies for Scleroderma, Localized across 9 countries. 4 are recruiting or about to start. 17 of them are mainly about Scleroderma, Localized (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-30.
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Who runs them
Hacettepe University (3) · University of Texas Southwestern Medical Center (3) · Duke University (2) · University of Utah (1) · University Children's Hospital, Zurich (1) · University of Alberta (1) · Vanderbilt University Medical Center (1) · University of Cologne (1)
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Jan 2027Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA Repository · University of Texas Southwestern Medical Center
- Jun 2027Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin Diseases · University of Utah
- Aug 2027Patients Diagnosed With Scleroderma: Physical Performance and Functionality · Hacettepe University
- Aug 2027Patients Diagnosed With Scleroderma and Their Chewing and Swallowing Performance · Hacettepe University
Who these studies take
Of the 4 Scleroderma, Localized studies recruiting now, 3 (75%) set no upper age limit and 0 (0%) stop at 75 or younger. 4 (100%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (100%) | 4 (100%) |
| 18 | 4 (100%) | 4 (100%) |
| 30 | 4 (100%) | 4 (100%) |
| 40 | 4 (100%) | 4 (100%) |
| 50 | 4 (100%) | 4 (100%) |
| 65 | 4 (100%) | 4 (100%) |
| 75 | 4 (100%) | 4 (100%) |
| 85 | 4 (100%) | 4 (100%) |
Across all 27 studies, recruiting or not: 11% stop at 75 or younger and 11% at 65; 48% take children; 0% are for women only and 0% for men only; 15% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 27 of 27. search them.
- Morphea in Adults and Children (MAC) Cohort Study: A Morphea Registry and DNA RepositoryRecruitingNCT018089371 country
- Investigating the Effectiveness of the Biopsychosocial Model-Based Exercise Approach in Children and Adults Diagnosed With SclerodermaRecruitingNCT07292961Not applicable1 country
- Patients Diagnosed With Scleroderma: Physical Performance and FunctionalityRecruitingNCT071830721 country
- Patients Diagnosed With Scleroderma and Their Chewing and Swallowing PerformanceRecruitingNCT071829811 country
- Patient Reported Outcomes With UVA-1 Therapy for Treatment of Sclerosing Skin DiseasesActive, not recruitingNCT04922736Not applicable1 country
- Study on the Efficacy of Autologous Fat Grafting in Improving Hair Transplantation Outcomes for Patients With Localized Scleroderma-Related AlopeciaCompletedNCT06646146Not applicable1 country
- Efficacy and Safety of Imatinib in SclerodermaCompletedNCT00479934Phase 21 country
- Photobiomodulation in Children With Localized SclerodermaCompletedNCT06621628Not applicable1 country
- Study on the Treatment With Water-filtered Infrared-A (wIRA) Radiation in Patients With Morphea and Sclerotic Graft-versus-host DiseaseTerminatedNCT04954573Not applicable1 country
- Clinical Trial to Evaluate Efficacy and Safety of Dupilumab in Localized SclerodermaCompletedNCT04200755Phase 21 country
- A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea)TerminatedNCT03740724Phase 1/21 country
- The Influence of Extracorporeal Photopheresis on Skin SclerosisCompletedNCT047523971 country
- Study to Assess Sarilumab in Halting Progression of MorpheaWithdrawnNCT03679845Phase 1/21 country
- Pilot Study Evaluating the Efficacy of a Topical PDE4 Inhibitor for MorpheaCompletedNCT03351114Phase 21 country
- Pain Outcomes Following Intralesional Corticosteroid InjectionsCompletedNCT03630198Phase 41 country
- Hyaluronidase in Treating Oral Microstomia in Patients With Sclerosing Skin DiseaseWithdrawnNCT04656704Early Phase 1
- Genetic Variants in Linear Localized SclerodermaCompletedNCT02222038Not applicable1 country
- Adult-onset Generalized MorpheaStatus unknownNCT042647281 country
- Treatment Study Comparing UVA-1 Phototherapy Versus Placebo Treatment for MorpheaCompletedNCT01799174Not applicable1 country
- Treatment Study Comparing Medium or High Dose Uva-1 Treatment 3x/Week Versus Fluocinonide 0.05% Cream in the Treatment of Morphea.CompletedNCT00812188Not applicable1 country
- Molecular Effects of Topical Calcipotriene on MorpheaTerminatedNCT02411643Early Phase 11 country
- The CARRA RegistryCompletedNCT016972541 country
- Ultraviolet B (UVB) Light Therapy in the Treatment of Skin Conditions With Altered Dermal MatrixCompletedNCT00129428Phase 1/21 country
- Imiquimod 5% Cream in Plaque-type Morphea: A Pilot, Prospective Open-label StudyWithdrawnNCT00230373Phase 31 country
- Fractional Carbon Dioxide Laser Versus UVA 1 in Treatment of Localized SclerodermaStatus unknownNCT02002897Not applicable1 country
- Imiquimod in Children With Plaque MorpheaCompletedNCT00147771Phase 31 country
- Study of Silicone-Associated Connective Tissue DiseasesCompletedNCT000013301 country