Rectal Neoplasms: all 1,804 studies
Page 2 of 19. Open to participants first (520), then studies with results posted, then the rest; newest registration first within each.
- Reporting of Tumour Deposits in Colorectal Cancer by Radiology and PathologyNot yet recruitingNCT07345273
- Use of a Novel Camera to Check the Bowel After Polyp or Tumour RemovalNot yet recruitingNCT07341126
- ProLARS Trial: Prospective Longitudinal Follow-up of Low Anterior Resection Syndrome (LARS) and COREFO Score After Rectum Surgery in Patients Undergoing Upfront Surgery or Different Neo-adjuvant Treatment RegimensRecruitingNCT07339904Not applicable
- Organ Preservation in Rectal Cancer by Dose Escalated MR Guided Adaptive RadiotherapyRecruitingNCT07337876Phase 2
- Injection of IP-001 Into Thermally Ablated Hepatic Tumors in Patients With Colorectal Liver MetastasesNot yet recruitingNCT07321847Phase 2/3
- Sample Collection for Ongoing Research and Product Evaluation StudyRecruitingNCT07318051
- Distribution and Analysis of Metastatic Lymph Nodes in Colorectal Cancer Patients (DIAMOND)Not yet recruitingNCT07306390
- Preventive Efficacy of Bergmann Enema for Acute Radiation-induced Rectal Injury in Rectal Cancer Patients Undergoing Short-course RadiotherapyNot yet recruitingNCT07302126Phase 2
- SIB-RT Combined With CAPOX and PD-1 for High-Risk Rectal CancerNot yet recruitingNCT07297030Phase 2
- Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation RatesRecruitingNCT07292298Phase 2
- SCRT VS LCRT Followed by PD-L1 Inhibitor Plus CAPEOX as TNT in Patients With LARCRecruitingNCT07284992Phase 2
- Studying the PAGODA Algorithm for Chemotherapy Dose Changes to Prevent Unplanned Treatment DelaysRecruitingNCT07283939Not applicable
- Capecitabine/Oxaliplatin Chemotherapy and Cemiplimab With or Without Fianlimab or REGN7075 in Locally Advanced Rectal CancerRecruitingNCT07281768Phase 2
- Application of Multimodal MRI in Histological Grading and Prognostic Assessment of Rectal CancerNot yet recruitingNCT07269912
- Response-adapted Total Neoadjuvant Therapy Guided by Induction Chemotherapy in Early- and Intermediate-risk Low Rectal Cancer for Implementation of a Watch-and-wait StrategyRecruitingNCT07260526
- Short Course or Long Course Radiotherapy as Total Neoadjuvant Therapy in Locally Advanced Rectal CancerNot yet recruitingNCT07258797Not applicable
- The Effects of Kegel Exercise Combined With Biofeedback Therapy on Bowel Function Recovery, Emotional Distress, and Quality of Life in Patients Following Low Anterior Resection for Rectal CancerEnrolling by invitationNCT07253298Not applicable
- A Phase II Single-Arm Study of High-Bioavailability Curcumin as Neoadjuvant Chemoradiotherapy in Mid-to-Low Rectal Cancer: Integrated Clinical and Translational Analysis of Tumor TissueNot yet recruitingNCT07248020Phase 2
- Extra-Peritoneal Tunneling Versus Conventional Drain Fixation After Anterior or Low Anterior ResectionNot yet recruitingNCT07241143Not applicable
- A Pilot Study Evaluating β-hydroxybutyrate Supplementation Concomitant to Short-Course Radiotherapy Followed by Immunotherapy Combined With CAPEOX Neoadjuvant Therapy in Patients With Locally Advanced Rectal CancerRecruitingNCT07239466Phase 2
- A Comparison of Endoscopic Synchronous Injection and Submucosal Dissection(ESISD) and Conventional Endoscopic Submucosal Dissection(CESD) for Granular Mixed Nodular Laterally Spreading Tumor in the Rectum (LST-G-M)Not yet recruitingNCT07236827Not applicable
- A Study of Botensilimab and Balstilimab for Colorectal Cancer With ctDNA+ After Surgery and ChemotherapyRecruitingNCT07227636Phase 2
- Adaptive Radiation Boost for Rectal CancerRecruitingNCT07221058Phase 1
- A Study to Investigate the Safety and Preliminary Efficacy of GSK5460025 Alone or in Combination With Other Anti-cancer Agents in Participants With Solid TumorsRecruitingNCT07213609Phase 1/2
- SIS-Reinforced vs. Conventional Anastomosis for Mid-to-Low Rectal Cancer: A Multicenter RCT on Anastomotic LeakRecruitingNCT07209787Phase 4
- ctDNA-Informed Management of Early-Stage Rectal CancerNot yet recruitingNCT07209215Phase 2
- SCRT Followed by CAPOX + Bev ± PD-1 Inhibitor for TNT in LARCRecruitingNCT07198165Phase 2
- Rectal Cancer CTC TrialRecruitingNCT07194616Not applicable
- ESD in Locally Advanced Rectal Cancer Following CRTNot yet recruitingNCT07192627
- 1. SAFE-AI ONCO-TRACK: Multimodal GenAI for Early Detection of Minimal Residual Disease and Recurrence in Gastrointestinal OncologyNot yet recruitingNCT07189520
- ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal CancerRecruitingNCT07188025Phase 3
- 3D Modeling for Detecting Locally Advanced Rectal Cancer With Positive Circumferential Resection MarginNot yet recruitingNCT07183124
- CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid TumorsRecruitingNCT07179692Phase 1
- Clinical Trial of Neoadjuvant mFOLFOX Plus Alvenor for LARC Patients With High YWHAB ExpressionRecruitingNCT07176182Phase 2
- QL1706 With Short-Course Radiotherapy and Chemotherapy for MSS Rectal CancerNot yet recruitingNCT07175636Phase 2
- SCRT Followed by AK112 in pMMR/MSS Mid-low Rectal CancerRecruitingNCT07162714Phase 2
- Involve-site Radiotherapy Combined With Chemotherapy and Immunotherapy as Neoadjuvant Treatment for Locally Advanced Rectal CancerNot yet recruitingNCT07161115Phase 2
- Comprehensive Analysis of Gut Microbiota Signatures in Metastatic Colorectal CancerRecruitingNCT07154173
- Low Powered Colorectal Anastomosis After Rectal Excision (OASIS)Not yet recruitingNCT07146334
- Family Communications After Genetic TestingRecruitingNCT07143487Not applicable
- Magnetic Resonance Imaging (MRI)-Guided Rectal Cancer Preservation ProgramNot yet recruitingNCT07134296Not applicable
- Neoadjuvant Chemoradiotherapy Combined With Immunotherapy and Anti-angiogenesis in Treating Locally Advanced Rectal CancerNot yet recruitingNCT07134218Phase 2/3
- Neoadjuvant Chemoradiotherapy Followed by Chemotherapy With or Without Tislelizumab for Resectable Ultra-low Rectal Cancer: The RELIEVE-02 StudyRecruitingNCT07132463Phase 3
- A Clinical Trial Comparing Long-Course Versus Short-Course Radiotherapy Followed by Immunotherapy Combined With Total Neoadjuvant Therapy (TNT) to Long-Course Radiotherapy Followed by TNT in Locally Advanced Rectal CancerRecruitingNCT07113275Phase 3
- ADAR1 Expression Level in Rectal CancerRecruitingNCT07108348
- Efficacy and Safety of Trastuzumab Biosimilars and Pertuzumab Biosimilars Combined With Chemotherapy for Neoadjuvant Treatment of Patients With Locally Advanced HER2-positive Rectal CancerRecruitingNCT07108127Phase 2
- A Study On The Prediction of Neoadjuvant Efficacy For Rectal Cancer Based On MR Cytometry Imaging and Deep-radiomicsEnrolling by invitationNCT07107815
- Study on the Efficacy and Safety of Neoadjuvant Radiotherapy Combined With Tislelizumab, Liposomal Irinotecan, and Capecitabine in the Treatment of pMMR Locally Advanced Rectal Adenocarcinoma With Low Rectal InvolvementRecruitingNCT07104604Phase 2
- Contribution of Preserving the Superior Left Colic Artery to the Vascularization of the Descending Colon Prior to Colorectal Anastomosis During Left-Sided or Rectal Resections for Colorectal or Ovarian Cancer. (Revascularisation Colique)RecruitingNCT07098182Not applicable
- Efficacy and Toxicity of Total Neoadjuvant Sandwich Treatment Via Short Course Radiotherapy in the Treatment of Stage II and III Rectal Cancer PatientsRecruitingNCT07095439Phase 2
- the Efficacy of MR-guided Online Adaptive Radiotherapy for Locally Advanced Rectal CancerNot yet recruitingNCT07080411Not applicable
- Planed Organ Preservation for Low Rectal Cancer After Neoadjuvant Chemotherapy (OPLAR)RecruitingNCT07070622Phase 3
- Node-Sparing Short-Course Radiation Combined With Capecitabine and PD-1/CTLA-4 for MSS Early Rectal CancerRecruitingNCT07068763Phase 2
- Distance-Based Exercise to Preserve Function and Prevent DisabilityRecruitingNCT07059884Not applicable
- Adaptive Anastomosis for Anterior Resection in Sigmoid and Proximal Rectal Cancer or Premalignant LesionsRecruitingNCT07056374
- Improving Diagnosis and Treatment for Patients With Rectal CancerNot yet recruitingNCT07054047Not applicable
- Knowledge-enhanced Digital Intervention to Prevent Low Anterior Resection SyndromeNot yet recruitingNCT07041515Not applicable
- Walking and Sitting Difficulties After Rectal Cancer SurgeryNot yet recruitingNCT07035600Not applicable
- Personalized Long-course Radiotherapy Plus Chemotherapy With or Without Immunotherapy for LARC: PALACE StudyRecruitingNCT07020247Phase 3
- A Study of Fruquintinib Plus FOLFIRI as Second-Line Treatment for Participants With Metastatic Colorectal Cancer (FRUITFUL)RecruitingNCT07011576Phase 2
- A Clinical Study of Calderasib (MK-1084) With Targeted Therapy and Chemotherapy in People With Colorectal Cancer (MK-1084-012/KANDLELIT-012)RecruitingNCT06997497Phase 3
- DESI - Düsseldorfer ESD StudyEnrolling by invitationNCT06993402
- Effect of Preserving the Left Colic Artery on Proximal Bowel PerfusionNot yet recruitingNCT06982664Not applicable
- Bovine Reinforcement in Stomach, Colorectal and Lung OperationRecruitingNCT06968221Phase 3
- Contrast-Enhanced Photon-Counting Detector CT (PCD-CT) for the Local Staging of Rectal CancerRecruitingNCT06965166
- Node-Sparing Short-Course Radiotherapy Sequential Chemotherapy and PD-1 Inhibitor for Mid/Low pMMR/MSS Rectal Cancer (MODIFI-RC-II)RecruitingNCT06958432Phase 2/3
- Preservation Vs. Dissection of No. 253 Lymph Nodes of Robotic Resection for Mid/Low Rectal CancerNot yet recruitingNCT06956976Not applicable
- A Global, Integrated, Personalized, Stage-related, Multimodal Therapeutic Approach for Rectal Adenocarcinoma Based on Organ Sparing and MininvasivityRecruitingNCT06952101Not applicable
- Tumor Local Excision +Postoperative Adjuvant Chemoradiotherapy for T1-2N0M0 Low/Ultra-Low Rectal CancerRecruitingNCT06949098Phase 2
- Safety and Efficacy Study of Single-port Robotic Versus Multi-port Robotic Radical Rectal Cancer SurgeryNot yet recruitingNCT06943690Not applicable
- Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer.RecruitingNCT06940388Phase 2
- Improving Functional Outcomes and Quality of Life in Patients With Rectal Cancer After Surgery With Intensified Follow-up & SurveillanceRecruitingNCT06936774Phase 3
- Neoadjuvant Radiochemotherapy Combined With QL1706 for Low Rectal CancerNot yet recruitingNCT06931873Early Phase 1
- Hypofractionated Radiotherapy Plus Immunotherapy Versus Conventional Radiotherapy in Locally Recurrent Rectal CancerRecruitingNCT06928584Phase 2
- Modified Long-Course Radiotherapy Followed by Chemotherapy and PD-1 Inhibitor for MSS/pMMR High-risk Mid/Low LARC (MODIFI-RC-I)RecruitingNCT06923345Phase 2
- A Randomised Clinical Investigation to Assess Efficacy of Low Volume Transanal Irrigation by Qufora® IrriSedo MiniGo Versus Conservative Treatment for Low Anterior Resection Syndrome PatientsRecruitingNCT06923150
- A Phase ll Study of Neoadjuvant Short-course Radiotherapy Followed by Ivonescimab and Chemotherapy in pMMR/MSS Locally Advanced Rectal CancerNot yet recruitingNCT06919510Phase 2
- Personalized Care Pathways for Bowel Symptoms in Rectal Cancer Patients_contributing Factors (Treatable)RecruitingNCT06914245Not applicable
- Radiotherapy Plus Iparomlimab and Tuvonralimab (QL1706), Regorafenib, and CAPOX as Neoadjuvant Therapy for pMMR/MSS LARC.RecruitingNCT06911684Phase 2
- Ovarian-Sparing Adaptive Radiotherapy in Young Adult WomenRecruitingNCT06904365
- Endoscopic Submucosal Dissection vs. Transanal Endoscopic Surgery for Rectal NeoplasiaNot yet recruitingNCT06902701
- Pre-Operative Treatment in REseCTable COlon CanceRNot yet recruitingNCT06899477Phase 3
- Latitude - Lateral Lymph Node Attitude StudyNot yet recruitingNCT06896578Not applicable
- Preoperative Chemoradiotherapy Combined With Consolidation or Induction NALIRIFOX in Rectal Cancer.RecruitingNCT06894797Not applicable
- Clinical Relevance of Pathologic Regression IN Lymph Node for Locally Advanced Rectal CancerEnrolling by invitationNCT06883084
- MRD-Guided Surveillance in Locally Advanced Mid-Low Rectal Cancer (SURVEILLANCE-III)Not yet recruitingNCT06879899
- Short-Course Radiotherapy Combined with Intracavitary Brachytherapy Followed by Pucotenlimab, Bevacizumab, Oxaliplatin, and Trifluridine/Tipiracil (TAS-102) for Total Neoadjuvant Therapy of Microsatellite Stable (MSS) Locally Advanced Low Rectal CancerNot yet recruitingNCT06872606Phase 2
- Dose Escalated Radiotherapy for Rectal Cancers Using MR-guided RadiotherapyRecruitingNCT06854679Not applicable
- Neoadjuvant Radiotherapy for Rectal Adenocarcinoma With Capecitabine Versus TAS-102 (Neo-REACT): A Multi-center, Randomized, Phase III TrialRecruitingNCT06850090Phase 3
- MR-guided Adaptive Radiotherapy Combined With PD-1 Antibody and CAPOX for Locally Advanced Rectal CancerRecruitingNCT06840665Phase 2
- Mepilex Lite Dressings for the Treatment of Acute Radiation Dermatitis of Anal Canal SkinRecruitingNCT06837831Not applicable
- Papaverine in Combination With Radiation Therapy for the Treatment of Locally Advanced Rectal Cancer, DINOMITE TrialRecruitingNCT06834126Phase 1
- Short-course Radiation (SCRT) Followed by 6 Cycles of Cadonilimab Plus MFOLFOX6 As Neoadjuvant Therapy for Patients with Locally Advanced Rectal Cancer (LARC): a Multicenter, Two-arm Parallel, Open-label, Randomised Phase III Trial (NeoCaCRT-III)Not yet recruitingNCT06832917Phase 3
- Hyperthermia With Chemoradiotherapy in Rectal CancerRecruitingNCT06831981Not applicable
- Metabolomics to Predict Treatment Response and Toxicities in Rectal CancerRecruitingNCT06831669
- Can Neoadjuvant Chemoradiotherapy be Ommited in Mid-rectal CancerNot yet recruitingNCT06823297
- Neoadjuvant FOLFIRINOX and Preoperative Chemoradiotherapy for Locally Advanced Rectal Cancer PatientsRecruitingNCT06812728Phase 2
- To Explore the Efficacy of Sintilimab Combined with Bevacizumab in Rectal CancerRecruitingNCT06808412Phase 2
- Image-Guided Surgery In The Treatment Of Rectal Cancer (AR_CRC)RecruitingNCT06805045Not applicable
- Short-course Radiotherapy Followed by AK112 and CAPOX as Neoadjuvant Therapy for Locally Advanced Rectal CancerRecruitingNCT06802666Phase 2