Pulmonary Arterial Hypertension: all 773 studies

Page 3 of 8. Open to participants first (142), then studies with results posted, then the rest; newest registration first within each.

• Bardoxolone Methyl in Patients With Connective Tissue Disease-associated Pulmonary Arterial Hypertension - CATALYSTTerminatedNCT02657356Phase 3Results posted
• Phase 1/1b Study With Nab-sirolimus for Patients With Severe Pulmonary Arterial HypertensionCompletedNCT02587325Phase 1Results posted
• Riociguat in Children With Pulmonary Arterial Hypertension (PAH)Active, not recruitingNCT02562235Phase 3Results posted
• The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial HypertensionCompletedNCT02558231Phase 3Results posted
• Positron Emission Tomography (PET) Study to Evaluate Biodistribution of [11C]-GSK2256098 in Healthy Subjects and Idiopathic Pulmonary Arterial Hypertension (PAH) PatientsCompletedNCT02551653Phase 1Results posted
• Beta-blockers in Pulmonary Arterial HypertensionTerminatedNCT02507011Phase 2Results posted
• Effect of Pharmacologic Interaction Between ERAs and PDE-5 Inhibitors on Medication Serum Levels and Clinical Disease Status in Patients With PAHCompletedNCT02484807Results posted
• Study to Assess the Tolerability and the Safety of the Transition From Inhaled Treprostinil to Oral Selexipag in Patients With Pulmonary Arterial HypertensionCompletedNCT02471183Phase 3Results posted
• REPAIR: Right vEntricular Remodeling in Pulmonary ArterIal hypeRtensionCompletedNCT02310672Phase 4Results posted
• Early Treatment of Borderline Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (SSc-APAH)CompletedNCT02290613Phase 2Results posted
• Long-term Safety and Efficacy of Ralinepag in Pulmonary Arterial HypertensionCompletedNCT02279745Phase 2Results posted
• Safety and Efficacy of APD811 in Pulmonary Arterial HypertensionCompletedNCT02279160Phase 2Results posted
• The Combination Ambrisentan Plus Spironolactone in Pulmonary Arterial Hypertension StudyTerminatedNCT02253394Phase 4Results posted
• Selonsertib in Adults With Pulmonary Arterial HypertensionCompletedNCT02234141Phase 2Results posted
• Measuring Outcomes In Patients With Pulmonary Arterial Hypertension Not on Active Treatment (MOTION)CompletedNCT02191137Phase 4Results posted
• A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and SpainTerminatedNCT02081690Phase 3Results posted
• Effects of Oral Sildenafil on Mortality in Adults With PAHTerminatedNCT02060487Phase 4Results posted
• Open-label, Multi-center Protocol to Provide QTI571 to PAH Patients Who Participated in the Extension Study (A2301E1) in JapanCompletedNCT02042014Phase 3Results posted
• Bardoxolone Methyl Evaluation in Patients With Pulmonary Hypertension (PH) - LARIATCompletedNCT02036970Phase 2Results posted
• Acute Dosing of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-003)TerminatedNCT01934647Phase 1Results posted
• A Pharmacokinetic Substudy of the TDE-PH-304 ProtocolCompletedNCT01934582Phase 3Results posted
• Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-005)CompletedNCT01926509Phase 1Results posted
• Beraprost-314d Added-on to Tyvaso® (BEAT)CompletedNCT01908699Phase 3Results posted
• Clinical Study of Macitentan in Patients With PAH to Psychometrically Validate PAH-SYMPACT InstrumentTerminatedNCT01847014Phase 3Results posted
• Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT InstrumentCompletedNCT01841762Phase 3Results posted
• A Study of Tadalafil in Pediatric Participants With Pulmonary Arterial Hypertension (PAH)CompletedNCT01824290Phase 3Results posted
• Efficacy Study of Ambrisentan in Chinese Patients With Pulmonary Arterial Hypertension (PAH)CompletedNCT01808313Phase 3Results posted
• A Rising Single Dose Study of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics of MK-8892 (MK-8892-001)CompletedNCT01798849Phase 1Results posted
• Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger SyndromeCompletedNCT01743001Phase 3Results posted
• Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger SyndromeTerminatedNCT01739400Phase 3Results posted
• Bosentan and Pulmonary Endothelial FunctionCompletedNCT01721564Not applicableResults posted
• FK506 (Tacrolimus) in Pulmonary Arterial HypertensionCompletedNCT01647945Phase 2Results posted
• Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial HypertensionCompletedNCT01642407Phase 4Results posted
• Remodulin® to Oral Treprostinil TransitionCompletedNCT01588405Phase 2Results posted
• PAHTCH Pulmonary Arterial Hypertension Treatment With Carvedilol for Heart Failure (Carvedilol)CompletedNCT01586156Not applicableResults posted
• An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial HypertensionCompletedNCT01560637Phase 3Results posted
• Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral MonotherapyCompletedNCT01560624Phase 3Results posted
• Assessmet of Patients With PAH Right Ventricular VolumeCompletedNCT01557582Not applicableResults posted
• Anastrozole in Patients With Pulmonary Arterial HypertensionCompletedNCT01545336Phase 2Results posted
• A Pharmacokinetics Study for Pediatric Participants With Pulmonary Arterial HypertensionCompletedNCT01484431Phase 1/2Results posted
• Addition of UT-15C SR to Pulmonary Arterial Hypertension Patients Currently Receiving Tyvaso®CompletedNCT01477333Phase 2Results posted
• Epoprostenol for Injection in Patients With Pulmonary Arterial HypertensionCompletedNCT01470144Phase 3Results posted
• Study of a New Thermo Stable Formulation of Epoprostenol Sodium to Treat Pulmonary Arterial Hypertension (PAH)CompletedNCT01462565Phase 4Results posted
• IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) PatientsCompletedNCT01447628Phase 2Results posted
• Pilot Chart Review Study Of Sitaxentan Sodium (Thelin) In Patients With Pulmonary Arterial Hypertension (PAH)CompletedNCT01445873Results posted
• Epoprostenol for Injection (EFI/ACT-385781A) - Pulmonary Arterial HypertensionCompletedNCT01431716Phase 3Results posted
• Extension to CQTI571A2102 to Evaluate Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)TerminatedNCT01392495Phase 3Results posted
• Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension ParticipantsCompletedNCT01392469Phase 3Results posted
• Evaluate The Clinical Effectiveness, Safety And Tolerability Of Sildenafil Used In Doses ≥20mg TID For The Treatment Of Pulmonary Arterial HypertensionCompletedNCT01365585Results posted
• Long-term Ambrisentan Extension Study for Pediatric Patients Who Participated in AMB112529CompletedNCT01342952Phase 2Results posted
• An Open-Label Uncontrolled Study of the Safety and Efficacy of Ambrisentan in Participants With Exercise-Induced Pulmonary Arterial Hypertension (PAH)CompletedNCT01338636Phase 4Results posted
• FUTURE 3 Study ExtensionCompletedNCT01338415Phase 3Results posted
• Efficacy and Safety of Ambrisentan in Children 8-18yrsTerminatedNCT01332331Phase 2Results posted
• Safely Change From Bosentan to Ambrisentan in Pulmonary HypertensionCompletedNCT01330108Phase 4Results posted
• DelIVery for Pulmonary Arterial Hypertension (PAH) & Continued Support StudyActive, not recruitingNCT01321073Not applicableResults posted
• Iloprost for the Treatment of Pulmonary Hypertension in Adults With Congenital Heart DiseaseTerminatedNCT01319045Not applicableResults posted
• Treprostinil Combined With Tadalafil for Pulmonary HypertensionTerminatedNCT01302444Phase 4Results posted
• Transition From Injectable Prostacyclin Medication to Inhaled Prostacyclin MedicationCompletedNCT01268553Phase 4Results posted
• Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH TherapiesCompletedNCT01266265Results posted
• The Qutenza Patch as Treatment for Disabling Treprostinil (Remodulin) Infusion Site PainCompletedNCT01260454Phase 2Results posted
• A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple DosesTerminatedNCT01244620Phase 1Results posted
• Effects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial HypertensionCompletedNCT01223352Phase 3Results posted
• Long-Term Open-Label, Safety Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension PatientsTerminatedNCT01210443Phase 3Results posted
• A 12 Week Safety And Efficacy Study Of Sitaxentan Sodium In Japanese Pulmonary Arterial Hypertension PatientsTerminatedNCT01204853Phase 3Results posted
• Efficacy, Safety, Tolerability and Pharmacokinetics (PK) of Nilotinib (AMN107) in Pulmonary Arterial Hypertension (PAH)TerminatedNCT01179737Phase 2Results posted
• A Study of First-Line Ambrisentan and Tadalafil Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)CompletedNCT01178073Phase 3Results posted
• Ranolazine and Pulmonary HypertensionCompletedNCT01174173Phase 3Results posted
• Nitric Oxide, GeNO Nitrosyl Delivery SystemCompletedNCT01165047Phase 2Results posted
• Coenzyme Q-10 and Pulmonary Arterial HypertensionCompletedNCT01148836Not applicableResults posted
• Extension to QTI571A2301 to Evaluate the Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH)TerminatedNCT01117987Phase 3Results posted
• ACT-293987 in Pulmonary Arterial HypertensionCompletedNCT01112306Phase 3Results posted
• Selexipag (ACT-293987) in Pulmonary Arterial HypertensionCompletedNCT01106014Phase 3Results posted
• Epoprostenol for Injection in Pulmonary Arterial Hypertension - Extension of AC-066A401CompletedNCT01105117Phase 4Results posted
• Epoprostenol for Injection in Pulmonary Arterial HypertensionCompletedNCT01105091Phase 4Results posted
• Pilot Study Evaluating the Safety and Performance of the GeNO NITROsyl Delivery System for Inhaled Nitric OxideCompletedNCT01092559Phase 2Results posted
• Rituximab for Treatment of Systemic Sclerosis-Associated Pulmonary Arterial Hypertension (SSc-PAH)CompletedNCT01086540Phase 2Results posted
• A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic SclerosisCompletedNCT01042158Phase 4Results posted
• A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary HypertensionCompletedNCT01028651Results posted
• An Open-Label Extension Trial of UT-15C Sustained-release (SR) in Subjects With Pulmonary Arterial HypertensionCompletedNCT01027949Phase 3Results posted
• A Non-Interventional, Patient Registry For The Collection Of Pre-Defined Safety Data In Patients Prescribed ThelinTerminatedNCT00995566Results posted
• Extension of BPS-MR-PAH-203 in Pulmonary Arterial Hypertension (PAH) PatientsCompletedNCT00990314Phase 2Results posted
• Dose-response Study of the Safety and Efficacy of Beraprost Sodium Modified Release (BPS-MR) in Patients With Pulmonary Arterial Hypertension (PAH)CompletedNCT00989963Phase 2Results posted
• Pilot Study of the Safety and Efficacy of Carvedilol in Pulmonary Arterial HypertensionCompletedNCT00964678Phase 1/2Results posted
• To Provide Sildenafil Therapy To Eligible Adult Patients With Pulmonary Arterial Hypertension For 112 WeeksCompletedNCT00946114Results posted
• Safety and Efficacy of Fluoxetine in Pulmonary Arterial HypertensionCompletedNCT00942708Phase 2Results posted
• Imatinib (QTI571) in Pulmonary Arterial HypertensionCompletedNCT00902174Phase 3Results posted
• Efficacy and Safety of Oral UT-15C Tablets to Treat Pulmonary Arterial HypertensionCompletedNCT00887978Phase 3Results posted
• BAY63-2521:Long-term Extension Study in Patients With Pulmonary Arterial HypertensionCompletedNCT00863681Phase 3Results posted
• A Research Study To Assess The Effectiveness And Safety Of Different Doses Of Oral PF-00489791 In The Treatment Of Adult Patients With Pulmonary Arterial HypertensionTerminatedNCT00853112Phase 2Results posted
• Insulin Resistance in Pulmonary Arterial HypertensionTerminatedNCT00825266Phase 2Results posted
• A Long-Term, Open-Label Study to Evaluate the Safety of Sitaxsentan Sodium Treatment in Patients With Pulmonary Arterial HypertensionTerminatedNCT00811018Phase 3Results posted
• A Study to Evaluate Efficacy and Safety of Oral BAY63-2521 in Patients With Pulmonary Arterial Hypertension (PAH)CompletedNCT00810693Phase 3Results posted
• Study Looking at Combination Therapy (Sitaxsentan+Sildenafil) Vs. Monotherapy (Sitaxsentan Alone) SR-PAAS -Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding SildenafilTerminatedNCT00796666Phase 3Results posted
• Study Providing Monotherapy (Sitaxsentan) And Combination Therapy (Sitaxsentan+Sildenafil) To Subjects With Pulmonary Arterial Hypertension (PAH) To Assess Long-Term SafetyTerminatedNCT00796510Phase 3Results posted
• Sitaxsentan Efficacy And Safety Trial With A Randomized Prospective Assessment Of Adding Sildenafil (SR-PAAS)TerminatedNCT00795639Phase 3Results posted
• An Open-Label Extension of BPS-MR-PAH-201 in Pulmonary Arterial Hypertension (PAH) PatientsCompletedNCT00792571Phase 2Results posted
• A Multi-Center, Open-Label, Multiple Dose, Dose Finding Study Exploring the Safety and Tolerability of Beraprost Sodium Modified Release in PAH PatientsCompletedNCT00781885Phase 2Results posted
• Safety Evaluation of Inhaled Treprostinil Administration Following Transition From Inhaled Ventavis in Pulmonary Arterial Hypertension (PAH) SubjectsCompletedNCT00741819Phase 4Results posted
• Iloprost Power Disc-15 in Pulmonary Arterial HypertensionTerminatedNCT00723554Phase 3Results posted
• Iloprost Power 15 in Pulmonary Arterial HypertensionCompletedNCT00709956Phase 3Results posted

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