Pulmonary Arterial Hypertension: all 773 studies

Page 4 of 8. Open to participants first (142), then studies with results posted, then the rest; newest registration first within each.

• Safety Study Extension of Iloprost Power 15 in Pulmonary Arterial HypertensionCompletedNCT00709098Phase 3Results posted
• Treprostinil Therapy For Patients With Interstitial Lung Disease And Severe Pulmonary Arterial HypertensionCompletedNCT00705133Phase 2Results posted
• Clinical Study to Assess the Long-term Safety and Tolerability of ACT 064992 in Patients With Symptomatic Pulmonary Arterial HypertensionCompletedNCT00667823Phase 3Results posted
• Study of Macitentan (ACT-064992) on Morbidity and Mortality in Patients With Symptomatic Pulmonary Arterial HypertensionCompletedNCT00660179Phase 3Results posted
• Rapid Switch From Flolan to Remodulin in the Outpatient ClinicTerminatedNCT00643604Phase 4Results posted
• Study of Add-on Ambrisentan Therapy to Background Phosphodiesterase Type-5 Inhibitor (PDE5i) Therapy in Pulmonary Arterial Hypertension (ATHENA-1)CompletedNCT00617305Phase 4Results posted
• A Long Term Study of Ambrisentan in Pulmonary Arterial Hypertension Subjects Having Completed AMB-320 (NCT00423748) or AMB-321 (NCT00423202)CompletedNCT00578786Phase 3Results posted
• A Study to Evaluate GSK1325760A - a Long-Term Extension StudyCompletedNCT00554619Phase 3Results posted
• Evaluate the Efficacy, Safety and Pharmacokinetics of GSK1325760A in the Treatment of Pulmonary Arterial HypertensionCompletedNCT00540436Phase 2Results posted
• Safety and Efficacy of Imatinib Mesylate in Patients With Pulmonary Arterial HypertensionCompletedNCT00477269Phase 2/3Results posted
• Open Label Study of Sildenafil in Patients With Pulmonary Arterial HypertensionCompletedNCT00454207Phase 3Results posted
• Safety, Efficacy, and Treatment Satisfaction Switching From Flolan to Remodulin Using the Crono Five Ambulatory Pump in Patients With PAHTerminatedNCT00439946Phase 4Results posted
• Combination Therapy in Pulmonary Arterial HypertensionCompletedNCT00433329Phase 4Results posted
• To Assess The Efficacy and Safety Of Oral Sildenafil in the Treatment of Pulmonary Arterial Hypertension.TerminatedNCT00430716Phase 4Results posted
• Phase 2 Study of Ambrisentan for Liver Function Test Rescue in Pulmonary Arterial HypertensionCompletedNCT00423592Phase 2Results posted
• A Study of Aspirin and Simvastatin in Pulmonary Arterial HypertensionTerminatedNCT00384865Phase 2Results posted
• BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger PhysiologyCompletedNCT00367770Phase 4Results posted
• FREEDOM-C: Oral Treprostinil in Combination With an Endothelin Receptor Antagonist (ERA) and/or a Phosphodiesterase-5 (PDE-5) Inhibitor for the Treatment of Pulmonary Arterial Hypertension (PAH)CompletedNCT00325442Phase 3Results posted
• FREEDOM - M: Oral Treprostinil as Monotherapy for the Treatment of Pulmonary Arterial Hypertension (PAH)CompletedNCT00325403Phase 3Results posted
• Assess the Efficacy and Safety of Sildenafil When Added to Bosentan in the Treatment of Pulmonary Arterial HypertensionCompletedNCT00323297Phase 4Results posted
• Bosentan in Children With Pulmonary Arterial Hypertension Extension StudyCompletedNCT00319020Phase 3Results posted
• Effects of the Combination of Bosentan and Sildenafil Versus Sildenafil Monotherapy on Pulmonary Arterial Hypertension (PAH)CompletedNCT00303459Phase 4Results posted
• The "VISION" Trial: Ventavis Inhalation With Sildenafil to Improve and Optimize Pulmonary Arterial HypertensionTerminatedNCT00302211Phase 3Results posted
• A Randomized, Double-Blind, Placebo-Controlled Study of Sildenafil in Children With Pulmonary Arterial Hypertension.CompletedNCT00159913Phase 3Results posted
• A Long Term Extension Study Evaluating Safety Of Sildenafil Citrate When Used To Treat Pulmonary Arterial Hypertension (PAH) In ChildrenCompletedNCT00159874Phase 3Results posted
• Clinical Investigation Into Inhaled Treprostinil Sodium in Patients With Severe Pulmonary Arterial Hypertension (PAH)CompletedNCT00147199Phase 3Results posted
• Microbiota Transplant With Antibiotic Preconditioning and Fiber Supplementation in PAH.Active, not recruitingNCT07751120Phase 1
• Multimodality RV Phenotyping for Risk Stratification and Short-Term Outcomes in Group 1 PAHActive, not recruitingNCT07667673
• Cognitive Alterations in Pulmonary Arterial Hypertension (PAH)Active, not recruitingNCT07391228
• Incorporating the Venous Excess Ultrasound Score (VExUS Score) Into Contemporary Haemodynamic Risk Assessment in Pulmonary Arterial Hypertension: The INVEXUS-PAH StudyCompletedNCT07266012
• The Effect of Slow-Paced Breathing on Patient Outcomes in Pulmonary Arterial HypertensionCompletedNCT07232368Not applicable
• A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)Active, not recruitingNCT07218029Phase 3
• Safety and Efficacy of Nebulized Nitroglycerin in Pulmonary Arterial HypertensionCompletedNCT07214129Not applicable
• Pharmacokinetics, Safety and Tolerability of Concurrent Doses of BIA 5-1058 and FurosemideCompletedNCT07173738Phase 1
• The Risk of Adverse Pregnancy Outcomes for Long-term Exposure to Air Pollution in Pregnant Patients With Pulmonary HypertensionCompletedNCT07164157
• Bioequivalence Study to Compare Selexipag 400mcg Film Coated Tablets (400 mcg Selexipag) Versus Uptravi® 400mcg Film Coated Tablets (400 mcg Selexipag)CompletedNCT06932198Phase 1
• A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-031/LIGHTRAY EXTENSION)Active, not recruitingNCT06925750Phase 2
• The Effects of Drug Candidate CS1 on Lung Structure and Function Utilizing FRICompletedNCT06907693
• Safety and Effectiveness of a Virtual Pediatric Cardiac Rehabilitation Program or Telerehabilitation in Children with Heart DiseaseCompletedNCT06819059Not applicable
• Evaluation of the Prevalence and Clinical Manifestation of SARS-CoV-2 Infection in a Population of Adult and Pediatric Patients With Congenital Heart DiseaseCompletedNCT06784687
• Melatonin for Pulmonary Hypertension in Full Term NeonatesCompletedNCT06685679Phase 3
• Evaluation of the Efficacy and Safety of Oxacom® in Patients With Pulmonary Arterial HypertensionActive, not recruitingNCT06683040Phase 2/3
• A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (PAH) (MK-7962-024)CompletedNCT06664801Phase 2
• A Phase 2 Study of IkT-001Pro in Pulmonary Arterial Hypertension (PAH)WithdrawnNCT06643143Phase 2
• Subcutaneous Treprostinil as a Bridge to Lung Transplantation in Severe Pulmonary Hypertension: A Single-Arm Retrospective StudyCompletedNCT06605326Phase 4
• Features of the Clinical Course and Prognosis in Patients With Idiopathic Pulmonary Hypertension When Using Modern Strategies of Specific TherapyActive, not recruitingNCT06587074
• Efficacy and Safety of High-Flow Nasal Cannula Versus Noninvasive Ventilation for Pulmonary Arterial Hypertension-Associated Acute Respiratory FailureActive, not recruitingNCT06582459
• Evaluation of the Role of Epstein-Bar Virus in Patients With Pulmonary Arterial HypertensionCompletedNCT06550648
• Safety and Impact of Low Resistance Exercise Training on Quality of Life in Pulmonary Arterial HypertensionCompletedNCT06543745Not applicable
• A Study of HS135 for the Treatment of Pulmonary Arterial Hypertension in AdultsTerminatedNCT06493461Phase 1
• Bioequivalence Study to Compare Bosentan 32 mg Dispersible Tablets Versus Tracleer® 32 mg TabletsCompletedNCT06484673Phase 1
• Sotatercept on Central Cardiopulmonary Performance and Peripheral Oxygen Transport During Exercise in Pulmonary Arterial HypertensionCompletedNCT06409026Phase 4
• Exercise Performance on Ambient Air vs. Low-Flow Oxygen Therapy in Pulmonary Vascular Disease (PVD)CompletedNCT06384534Not applicable
• Safety and Efficacy of Continued CS1 Treatment of Patients With Pulmonary Arterial HypertensionNo longer availableNCT06321705
• Physical Activity and Various Aspects of Quality of Life in Patients With Pulmonary Arterial Hypertension (Ph-PAH)CompletedNCT06312111Not applicable
• Efficacy of Triple-Combination Therapy in Severe PAH-CHDActive, not recruitingNCT06196801
• Bioequivalence Study of Riociguat 2.5 mg Film Coated Tablets and Adempas (Riociguat) 2.5 mg Film Coated TabletsCompletedNCT06180096Phase 1
• A Study to Learn About the Study Medicine Called PF-07868489 in Healthy Adult People and in People With Pulmonary Arterial HypertensionCompletedNCT06137742Phase 1/2
• Xenon MRI in Stable Pulmonary Hypertension (Jupiter AUGEAN)WithdrawnNCT06122922Phase 2
• High Altitude (HA) Residents With Pulmonary Vascular Diseseases (PVD), Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) vs Sea Level (LA)Active, not recruitingNCT06092424Not applicable
• HA Residents With PVD, Pulmonary Artery Pressure (PAP) Assessed at HA (2840m) With and Without Supplemental Oxygen Therapy (SOT)Active, not recruitingNCT06084559Not applicable
• HA Residents With PVD, SDB Assessed at HA (2840m) vs LA (Sea Level)Active, not recruitingNCT06072417Not applicable
• Safety and Efficacy of BIA 5-1058 in PAHCompletedNCT06009185Phase 2
• High Altitude (HA) Residents With Pulmonary Vascular Diseases (PVD), 6 Minute Walk Distance (6MWD) Assessed at 2840m (HA) With and Without Supplemental Oxygen Therapy (SOT)Active, not recruitingNCT06003244Not applicable
• HA Residents With PVD, 6MWD Assessed at HA (2840m) vs LA (Sea Level)Active, not recruitingNCT05996302Not applicable
• A Study of Pulmonary Hypertension Peripheral LimitationsCompletedNCT05968859Not applicable
• The Safety, Tolerability, and Pharmacokinetics of TPN171H Tablets in Patients With Pulmonary Arterial HypertensionCompletedNCT05948644Phase 1
• Effects of UE Aerobic Exercise on Exercise Capacity and PA in Patients With Pulmonary Arterial Hypertension.CompletedNCT05947240Not applicable
• Supervised Endurance Training Among Pulmonary Arterial Hypertension PatientsCompletedNCT05947032Not applicable
• Safety, Tolerability and Pharmacokinetics of L608 in Healthy AdultsCompletedNCT05938946Phase 1
• Efficacy and Safety of Seralutinib in Adult Subjects With PAH (PROSERA)CompletedNCT05934526Phase 3
• Prognostic Value of Estimated Plasma Volume in Pulmonary HypertensionCompletedNCT05861479
• Pulmonary Hypertension: Intensification and Personalisation of Combination RxActive, not recruitingNCT05825417Phase 4
• Novel Index (PIMR) in PAHCompletedNCT05812976
• Lipid Balance in Adult Sickle Cell PatientsActive, not recruitingNCT05780775Not applicable
• StratosPHere (Non-interventional Study)CompletedNCT05767918
• A Study of Macitentan in Children Below 2 Years of AgeWithdrawnNCT05731492Phase 1
• Satralizumab in the Treatment of Pulmonary Arterial Hypertension (SATISFY-JP Trial)CompletedNCT05679570Phase 2
• An Extension Study of Treprostinil Palmitil Inhalation Powder (TPIP) for Pulmonary Arterial Hypertension (PAH)Active, not recruitingNCT05649748Phase 2/3
• Non-invasive Pulmonary Artery Prediction (ADOPTS)Status unknownNCT05641675
• Assessment of Right Ventricular Function by Cardiac MRI in Patients With Pulmonary Arterial Hypertension (IRMA)CompletedNCT05624242
• Non-invasive Pulmonary Artery PredictionStatus unknownNCT05622695
• Non-Invasive Measurement of Cardiac Output and Stroke Volume in PAH/CTEPHWithdrawnNCT05618093Not applicable
• RWD Patients With Pulmonary Arterial Hypertension Treated With IP Prostacyclin Receptor AgonistsStatus unknownNCT05600218
• Consistency of Electrical Cardiometry and Pulmonary Artery CatheterStatus unknownNCT05587400Not applicable
• Efficacy and Safety Evaluation of Tolvaptan in the Treatment of Patients With RHF Caused by PAHStatus unknownNCT05569655Not applicable
• A Healthy Volunteer Study Evaluating the the Safety, Tolerability, and Pharmacokinetics of RT234CompletedNCT05567367Phase 1
• a Non-interventional Study of Sildenafil in the Treatment of Pulmonary Arterial Hypertension (PAH) in Adults From ChinaCompletedNCT05546125
• Home-based Pulmonary Rehabilitation With Remote Monitoring in Pulmonary Arterial HypertensionCompletedNCT05521113
• Empagliflozin in Pulmonary Arterial HypertensionCompletedNCT05493371Phase 2
• Evaluation of the Strength of Handgrip in Patients With Pulmonary Artery HypertensionStatus unknownNCT05447390Not applicable
• Efficacy and Safety Study of Ambrisentan in Chinese Patients With Pulmonary Arterial HypertensionCompletedNCT05437224Phase 3
• A Study of Single and Multiple Doses of Different Formulations of a Prostacyclin Receptor AgonistCompletedNCT05427162Phase 1
• Assessing the Repeatability of NT-proBNP Testing Using Laboratory and Point of Care Testing in PAHCompletedNCT05421949
• Algorithms to Diagnose Pulmonary Arterial HypertensionStatus unknownNCT05417373
• A Dose Escalation Study to Evaluate the Effect of RT234 in Subjects With Pulmonary Arterial HypertensionCompletedNCT05343637Phase 2
• Prognostic Value of the Right Ventricular Function by Portable Ultrasound in Patients With Pulmonary Hypertension.Status unknownNCT05343091
• Developing Hyperpolarized 129Xe MRI Biomarkers for Evaluation of Pulmonary Arterial HypertensionCompletedNCT05339386
• A nUtrition and Lifestyle Intervention in Patients With Pulmonary Arterial HypertensIonCompletedNCT05318950Not applicable
• Exercise Training in Patients With Pulmonary Arterial HypertensionCompletedNCT05242380Not applicable

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