Protamines clinical trials
Also written Protamine sulfate.
How each study uses Protamines is sorted by a rule, right about nine times in ten. Readers can ask us to read every study one by one.Ask us to read each study
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Example · made-up studies
Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
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Approvals
The first approval found in each region, with its record
- United States
- 13 Aug 1969 · PROTAMINE SULFATE · NDA 006460 (FDA, Drugs@FDA)
- European Union
- Not in EMA's list of EU-wide authorisations
From FDA's Drugs@FDA and Purple Book (through openFDA) and the European Medicines Agency, files of Sept 2026 and 27 Oct 2026. National approvals in Europe and other countries are not included. How this is worked out
Studies by the year they started
6 studies that test it; most in 2016 (1)
| Year | Studies |
|---|---|
| 2016 | 1 |
| 2017 | 1 |
| 2018 | 1 |
| 2023 | 1 |
| 2024 | 1 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
What it is tested for
Each study’s main condition, where its own words name it, so a study counts once.
Who runs them
Industry 0 · Other 6
St. Antonius Hospital (1) · Medical University of Warsaw (1) · University of Michigan (1) · University of Liege (1) · Sohag University (1) · London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's (1)
Studies
Open first, then newest update. How each study uses Protamines is read from its arms, and is right about nine times in ten. Ask us to read each study. These are the studies that list it as an intervention; a search of ClinicalTrials.gov also finds studies that mention it only in a description, such as earlier treatment.
Testing it · 6
- Dose for Reversal of Heparin After Cardiopulmonary BypassRecruitingNot applicableSohag UniversityNCT07477977Written as Protamine sulfate
- Impact of Protamine Dose Reduction on Platelet Aggregation After Extracorporeal Circulation for Minimally Invasive Aortic Valve Replacement SurgeryNot yet recruitingNot applicableUniversity of LiegeNCT06254404Written as Low dose protamine
- Routine Versus Selective Protamine Administration to Reduce Bleeding Complications After Transcatheter Aortic Valve Implantation (POPular ACE TAVI)CompletedPhase 4St. Antonius HospitalNCT05774691Written as Protamine sulfate
- Protamine Sulfate During Transcatheter Aortic Valve ImplantationCompletedPhase 4Medical University of WarsawNCT02974660Written as Protamine sulfate
- Systematic Evaluation of Protamine Doze in Cardiac SurgeryStatus unknownNot applicableLondon Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph'sNCT03787641Written as Protamine Sulfate
- Use of Protamine for Heparin Reversal After Catheter Ablation of Atrial FibrillationCompletedPhase 4University of MichiganNCT03140631Written as Protamine Sulfate
As the comparator · 1 — what is tested is compared with Protamines
Codes
What other systems call Protamines · ClinicalTrials.gg INT008119
- MeSH (NLM) D011479ProtaminesConfirmed ClinicalTrials.gov, Wikidata
- UNII (FDA) 72G3UY6T4NPROTAMINEConfirmed FDA, Wikidata
- RxNorm 8826Confirmed FDA, Wikidata
- Wikidata Q5449573protamineConfirmed FDA, Wikidata
- NCI Thesaurus C84122ProtamineOne source FDA
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | D011479 | Protamines | Confirmed ClinicalTrials.gov, Wikidata |
| UNII (FDA) | 72G3UY6T4N | PROTAMINE | Confirmed FDA, Wikidata |
| RxNorm | 8826 | — | Confirmed FDA, Wikidata |
| Wikidata | Q5449573 | protamine | Confirmed FDA, Wikidata |
| NCI Thesaurus | C84122 | Protamine | One source FDA |
Also registered as protamine sulfate (UNII 0DE9724IHC · RxNorm 8825).
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.