Drug
Nitisinone clinical trials
Also written Orfadin.
- studies test it
- 14
- open now
- 0
- in phase 3
- 3
- first study started
- 2005
How studies write it
Studies that test it under each name
Studies by the year they started
14 studies that test it; most in 2013 (3)
| Year | Studies |
|---|---|
| 2005 | 1 |
| 2011 | 1 |
| 2012 | 2 |
| 2013 | 3 |
| 2014 | 2 |
| 2015 | 2 |
| 2016 | 1 |
| 2017 | 1 |
| 2019 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 8
- Phase 2
- 4
- Phase 3
- 3
- No phase
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 9 · Other 5
Swedish Orphan Biovitrum (5) · Cycle Pharmaceuticals Ltd. (3) · University of Liverpool (2) · National Human Genome Research Institute (NHGRI) (1) · University of California, San Diego (1) · National Eye Institute (NEI) (1) · Sutphin Drugs (1)
Often tested with
Tested in the same studies.
Tolbutamide (1) · Metoprolol (1) · Chlorzoxazone (1) · Furosemide (1)
Studies
Open first, then newest update. How each study uses nitisinone is read from its arms, and is right about nine times in ten.
Testing it · 14
- Bioequivalence of Orfadin 20 mg Compared to Orfadin 10 mg Capsules.CompletedPhase 1Swedish Orphan BiovitrumNCT01857362Written as Nitisinone 20 mg
- Long-Term Study of Nitisinone to Treat AlkaptonuriaCompletedPhase 2National Human Genome Research Institute (NHGRI)NCT00107783Written as Nitisinone (NTBC)
- Nitisinone (NTBC) In Different Age Groups Of Patients With AlkaptonuriaCompletedPhase 2/3University of California, San DiegoNCT01390077Written as Nitisinone
- Bio Equivalency 20 Mgm Orfadin and 20 Mgm of NitisonineStatus unknownNot applicableSutphin DrugsNCT04113772Written as Nitisinone
- Nitisinone for Type 1B Oculocutaneous AlbinismCompletedPhase 1/2National Eye Institute (NEI)NCT01838655Written as Nitisinone
- Suitability of Nitisinone in Alkaptonuria 2Status unknownPhase 3University of LiverpoolNCT01916382Written as Nitisinone
- A Study to Investigate the Potential Influence of Nitisinone on the Metabolism and the Transport of Other Drugs in Healthy VolunteersCompletedPhase 1Swedish Orphan BiovitrumNCT03103568Written as Nitisinone in Arm A
- Bioequivalence Study of Two Oral Nitisinone Formulations to Treat Hereditary Tyrosinemia (HT-1)CompletedPhase 1Cycle Pharmaceuticals Ltd.NCT02750345Written as Nitisinone
- Bioavailability Food-Effect Study of an Oral Nitisinone Formulation to Treat Hereditary Tyrosinemia (HT-1)CompletedPhase 1Cycle Pharmaceuticals Ltd.NCT02750332Written as Nitisinone
- Bioequivalence Study of Two Nitisinone Formulations Compared to OrfadinCompletedPhase 1Cycle Pharmaceuticals Ltd.NCT02750709Written as Nitisinone
- Efficacy and Safety of Once Daily Dosing Compared to Twice Daily Dosing of Nitisinone in HT-1CompletedPhase 3Swedish Orphan BiovitrumNCT02323529Written as Nitisinone
- Taste and Palatability of Orfadin SuspensionCompletedPhase 1Swedish Orphan BiovitrumNCT01734889Written as Nitisinone
- Dose Response Study of Nitisinone in AlkaptonuriaCompletedPhase 2University of LiverpoolNCT01828463Written as Nitisinone
- Bioequivalence of Orfadin Suspension Compared to Orfadin Capsules, and the Effect of Food on the Bioavailability of the SuspensionCompletedPhase 1Swedish Orphan BiovitrumNCT01682538Written as Nitisinone, capsule
Codes
What other systems call nitisinone · ClinicalTrials.gg INT003664
- MeSH (NLM) C077073nitisinoneConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) K5BN214699NITISINONEConfirmed FDA, NLM, Wikidata
- RxNorm 61805Confirmed FDA, Wikidata
- Wikidata Q3877355nitisinoneConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C61862NitisinoneOne source FDA
- DrugBank DB00348One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C077073 | nitisinone | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | K5BN214699 | NITISINONE | Confirmed FDA, NLM, Wikidata |
| RxNorm | 61805 | — | Confirmed FDA, Wikidata |
| Wikidata | Q3877355 | nitisinone | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C61862 | Nitisinone | One source FDA |
| DrugBank | DB00348 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.