Parathyroid Neoplasms clinical trials
The registry lists 63 studies for Parathyroid Neoplasms across more than 10 countries. 19 are recruiting or about to start. 28 of them are mainly about Parathyroid Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.
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Status
Who runs them
National Cancer Institute (NCI) (5) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (4) · M.D. Anderson Cancer Center (4) · Aristotle University Of Thessaloniki (3) · Kyowa Kirin Co., Ltd. (2) · Amgen (2) · Valerio Therapeutics (2) · European Organisation for Research and Treatment of Cancer - EORTC (1)
What is being tested here
Drugs under test in Parathyroid Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Liposomal Bupivacaine | 1 | 0 | 1 |
| Bupivacaine | 1 | 0 | 1 |
| Lenvatinib | 1 | 0 | 1 |
| Cinacalcet | 0 | 2 | 3 |
| Nivolumab | 0 | 0 | 2 |
| Denosumab | 0 | 1 | 2 |
| Belinostat | 0 | 0 | 2 |
| Ipilimumab | 0 | 0 | 1 |
| Gallium Ga 68 dotatate | 0 | 0 | 1 |
| Evocalcet | 0 | 1 | 1 |
Drug classes tested here HDAC inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4, phase 3 first
- Jul 202799mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CT · Phase 3 · Andrei Iagaru
- Jan 2027High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection Margins · Algemeen Ziekenhuis Maria Middelares
- Jul 2027Agnostic Therapy in Rare Solid Tumors · Instituto do Cancer do Estado de São Paulo
- Sep 2027Parathyroid Adenoma Detection With Rubidium-82 Imaging · Matthieu Pelletier-Galarneau, MD MSc
Who these studies take
Of the 10 Parathyroid Neoplasms studies recruiting now, 7 (70%) set no upper age limit and 0 (0%) stop at 75 or younger. 4 (40%) take children under 18. 1 (10%) are for women only and 0 (0%) for men only; 1 (10%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (40%) | 4 (40%) |
| 18 | 10 (100%) | 9 (90%) |
| 30 | 10 (100%) | 9 (90%) |
| 40 | 10 (100%) | 9 (90%) |
| 50 | 10 (100%) | 9 (90%) |
| 65 | 10 (100%) | 9 (90%) |
| 75 | 10 (100%) | 9 (90%) |
| 85 | 9 (90%) | 9 (90%) |
Across all 63 studies, recruiting or not: 2% stop at 75 or younger and 0% at 65; 22% take children; 2% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 50 of 63. Browse all 63 → or search them.
- Natural History Study of Parathyroid DisordersRecruitingNCT049699261 country
- Prospective Comprehensive Molecular Analysis of Endocrine NeoplasmsRecruitingNCT010056541 country
- Accuracy of 18F-Fluorocholine PET/MR and NeuroEXPLORER PET/CT Imaging for Localization of Parathyroid TumorsRecruitingNCT07444723Phase 2/31 country
- Parathyroid Adenoma Detection With Rubidium-82 ImagingEnrolling by invitationNCT070994041 country
- Radiofrequency Ablation For Recurrent Parathyroid CarcinomaRecruitingNCT07475780Not applicable1 country
- Lenvatinib in Patients With Advanced Parathyroid CarcinomaNot yet recruitingNCT07843901Phase 2
- 99mTc Sestamibi SPECT/CT vs 18F Fluorocholine PET/CTRecruitingNCT05891769Phase 2/31 country
- Molecular and Immunohistochemical Profiling of Tumors in Patients With Parathyroid TumorsRecruitingNCT030394391 country
- Comparison of NeuroEXPLORER PET/CT Versus Standard-of-care PET/CT of the Head and Neck Region.Enrolling by invitationNCT07595666Not applicable1 country
- Parathyroid Tumor Clonal StatusRecruitingNCT059978101 country
- Aldosterone Variations in Patients With Primary Hyperparathyroidism After SurgeryNot yet recruitingNCT073889141 country
- Expanded Access:18F-Fluorocholine for the Detection of Parathyroid AdenomasAvailableNCT07218224
- WHITE CAP: Intra-operative Parathyroid Tissue Sensor (PTS)-Guided Assessment of Parathyroid Viability and Surgical Decision-MakingNot yet recruitingNCT07043010Not applicable1 country
- PTeye in Parathyroid AdenomaRecruitingNCT069132961 country
- PET-TC in Thyroid EvaluationEnrolling by invitationNCT068521441 country
- High-resolution PET-CT Specimen Imaging for the Perioperative Visualization of Resection MarginsRecruitingNCT06835426Not applicable1 country
- Institution of an Italian Multicenter Database of Patients with Parathyroid Carcinoma or Atypical Parathyroid AdenomaRecruitingNCT066459511 country
- Exparel Injection Effect on Postoperative Opioid UsageEnrolling by invitationNCT04085913Early Phase 11 country
- The Bone-parathyroid Crosstalk in Primary HyperparathyroidismNot yet recruitingNCT055564991 country
- Agnostic Therapy in Rare Solid TumorsActive, not recruitingNCT06638931Phase 21 country
- Nivolumab and Ipilimumab in Treating Patients With Rare TumorsActive, not recruitingNCT02834013Phase 22 countries
- Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During ParathyroidectomyCompletedNCT05152927Not applicable1 country
- Evaluating Impact of Near Infrared Autofluorescence (NIRAF) Detection for Identifying Parathyroid Glands During ParathyroidectomyCompletedNCT05022641Not applicable1 country
- Intraoperative Identification of Parathyroid Adenomas Using PTeye™ and FLUOBEAM® LX: a Prospective Cohort StudyActive, not recruitingNCT067882231 country
- Near Infrared Autofluorescence Imaging in Minimally-Invasive Video-Assisted Parathyroidectomy (NIRAF MIVAP Study)CompletedNCT067797601 country
- The Registry of Oncology Outcomes Associated with Testing and TreatmentCompletedNCT040284791 country
- STP.168 Clinical Study Protocol ParakeetActive, not recruitingNCT06499142Not applicable1 country
- Evaluating Impact of NIRAF Detection for Identifying Parathyroid Glands During ParathyroidectomyCompletedNCT04299425Not applicable1 country
- A Retrospective Analysis of the Diagnostic Performance of 11C-choline PET/CT in Primary HyperparathyroidismCompletedNCT04608253
- Lidocaine And Neuromonitoring in Thyroid SurgeryCompletedNCT04574947Phase 41 country
- Trial Comparing 2 Diagnostic Strategies for Preoperative Localization of Parathyroid Adenoma in Primary Hyperparathyroidism:TEMP / CT With Tc99m-sestaMIBI or PET / CT With F18-choline in First IntentionCompletedNCT04040946Phase 31 country
- European Multicentric Study on Parathyroid CarcinomaStatus unknownNCT057896801 country
- Optimization and Individualization of Diagnostic Scintigraphy Protocol and Minimally Invasive Radio-guided Parathyroid SurgeryCompletedNCT04344886Not applicable1 country
- Studies of Elevated Parathyroid ActivityCompletedNCT00001277Phase 21 country
- Preoperational Fine Needle Aspiration of Pathological Parathyroid GlandWithdrawnNCT03516747Not applicable1 country
- Omission of Intact Parathyroid Hormone Testing During Surgery in Treating Patients With Primary HyperparathyroidismCompletedNCT03011736Not applicable1 country
- The Feasibility of Bilateral Intermediate Cervical Plexus Block for Thyroidectomy/ParathyroidectomyCompletedNCT049056411 country
- Phase 3 Study of KHK7580 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Primary HyperparathyroidismCompletedNCT03280264Phase 31 country
- Treatment of Primary Hyperparathyroidism With Denosumab and Cinacalcet.CompletedNCT03027557Phase 31 country
- Minimizing Narcotic Analgesics After Endocrine SurgeryCompletedNCT03469310Phase 41 country
- The Utility of 18F-fluorocholine PET/CT in the Imaging of Parathyroid AdenomasCompletedNCT04570033Not applicable
- Radioactive Drug (177Lu-DOTATATE) for the Treatment of Locally Advanced, Metastatic, or Unresectable Rare Endocrine CancersWithdrawnNCT04106843Phase 21 country
- Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects With Elevated Serum CalciumCompletedNCT00896454Phase 25 countries
- The ISET (Isolation by Size of Epithelial Tumor Cells) and the CellSearch Methods in Malignant Pleural MesotheliomaCompletedNCT01776385Not applicable1 country
- Parathyroid Cancer Versus Atypical Parathyroid Neoplasm; Investigating Their Clinical Characteristics and Biological BehaviorCompletedNCT030465241 country
- High Intensity Focused Ultrasound (HIFU) for Parathyroid AdenomaTerminatedNCT01291498Not applicable1 country
- An Intra-individual Titration Study of KRN1493 for the Treatment of Hypercalcemia in Patients With Parathyroid Carcinoma or Intractable Primary HyperparathyroidismCompletedNCT01460030Phase 31 country
- Safety Study of Dacarbazine and Bortezomib in Melanoma and Soft Tissue SarcomaCompletedNCT00580320Phase 11 country
- Multicenter Registry Comparing Preoperative Imaging for Primary HyperparathyroidismWithdrawnNCT02381925
- Study of PXD101 Alone and in Combination With 5-Fluorouracil (5-FU) in Patients With Advanced Solid TumorsCompletedNCT00413322Phase 11 country