Drug
Belinostat clinical trials
Also written PXD101 and Beleodaq.
- studies test it
- 50
- open now
- 1
- in phase 3
- 1
- first study started
- 2005
Keep track of what changes. Save the belinostat studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Studies by the year they started
50 studies that test it; most in 2006 (13)
| Year | Studies |
|---|---|
| 2005 | 3 |
| 2006 | 13 |
| 2007 | 3 |
| 2008 | 1 |
| 2009 | 3 |
| 2010 | 5 |
| 2011 | 1 |
| 2012 | 1 |
| 2013 | 2 |
| 2014 | 2 |
| 2015 | 2 |
| 2016 | 5 |
| 2019 | 1 |
| 2020 | 1 |
| 2021 | 3 |
| 2022 | 1 |
| 2023 | 2 |
| 2026 | 1 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 31
- Phase 2
- 26
- Phase 3
- 1
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 17 · Other 33
National Cancer Institute (NCI) (19) · Valerio Therapeutics (9) · Acrotech Biopharma Inc. (6) · University of Utah (2) · Spectrum Pharmaceuticals, Inc (2) · M.D. Anderson Cancer Center (2) · H. Lee Moffitt Cancer Center and Research Institute (1) · Emory University (1)
Often tested with
Tested in the same studies.
Carboplatin (5) · Paclitaxel (4) · Doxorubicin (3) · Cyclophosphamide (2) · Vincristine (2) · Prednisone (2) · Bortezomib (2) · Pralatrexate (1)
Studies
Open first, then newest update. How each study uses belinostat is read from its arms, and is right about nine times in ten.
Testing it · 50
- A UGT1A1 Genotype-Directed Study of Belinostat Pharmacokinetics and ToxicityRecruitingPhase 2National Cancer Institute (NCI)NCT06406465Written as Belinostat
- To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCLActive, not recruitingPhase 3Acrotech Biopharma Inc.NCT06072131Written as Belinostat Injection
- Tremelimumab + Durvalumab(MEDI4736)+ Belinostat in Urothelial CarcinomaCompletedPhase 1University of UtahNCT05154994Written as Belinostat
- Testing the Safety of the Anti-cancer Drugs Tazemetostat and Belinostat in Patients With Lymphomas That Have Resisted TreatmentActive, not recruitingPhase 1National Cancer Institute (NCI)NCT05627245Written as Belinostat
- Testing the Combination of Belinostat and SGI-110 (Guadecitabine) or ASTX727 for the Treatment of Unresectable and Metastatic Conventional ChondrosarcomaActive, not recruitingPhase 2National Cancer Institute (NCI)NCT04340843Written as Belinostat
- Ribociclib&Belinostat In Patients w Metastatic Triple Neg Breast Cancer & Recurrent Ovarian Cancer w Response Prediction By GenomicsTerminatedPhase 1University of UtahNCT04315233Written as Belinostat
- Binimetinib Plus Belinostat for Subjects With Metastatic Uveal MelanomaActive, not recruitingPhase 2H. Lee Moffitt Cancer Center and Research InstituteNCT05170334Written as Belinostat
- Belinostat Therapy With Zidovudine for Adult T-Cell Leukemia-LymphomaCompletedPhase 2University of MiamiNCT02737046Written as Belinostat
- Pevonedistat and Belinostat in Treating Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic SyndromeTerminatedPhase 1National Cancer Institute (NCI)NCT03772925Written as Belinostat
- Phase I Trial of AZD1775 and Belinostat in Treating Patients With Relapsed or Refractory Myeloid Malignancies or Untreated Acute Myeloid LeukemiaTerminatedPhase 1National Cancer Institute (NCI)NCT02381548Written as Belinostat
- Establish the PK of Belinostat in Patients With Wild-type, Heterozygous, and Homozygous UGT1A1*28 GenotypesCompletedPhase 1Acrotech Biopharma Inc.NCT02680795Written as Belinostat IV
- Talazoparib in Combination With Belinostat for Metastatic Breast Cancer, Metastatic Castration Resistant Prostate Cancer, and Metastatic Ovarian CancerCompletedPhase 1University of Michigan Rogel Cancer CenterNCT04703920Written as Belinostat
- MRSI to Predict Response to RT/TMZ ± Belinostat in GBMActive, not recruitingPhase 2Emory UniversityNCT02137759Written as Belinostat
- Belinostat in Relapsed or Refractory Peripheral T-Cell LymphomaCompletedPhase 2Spectrum Pharmaceuticals, IncNCT00865969Written as Belinostat
- A Trial of Belinostat in Combination With Erlotinib in Patients With Non-small Cell Lung CancerTerminatedPhase 1/2Herlev HospitalNCT01188707Written as Belinostat and Erlotinib
- MTD Study PXD-101 in Combination With Paclitaxel + Carboplatin in Chemotherapy-Naive Patients With Stage IV NSCLCCompletedPhase 1/2Acrotech Biopharma Inc.NCT01310244Written as Belinostat, Carboplatin, Paclitaxel
- Phase I Mass Balance, PK and Safety Study of 14C-Labeled Belinostat in Patients With Advanced CancerCompletedPhase 1Acrotech Biopharma Inc.NCT01583777Written as Belinostat
- Phase 1 Dose Finding Study of Belinostat for Treatment of Patients With Peripheral T-cell Lymphoma (PTCL)CompletedPhase 1Acrotech Biopharma Inc.NCT01839097Written as Belinostat
- To Evaluate Safety and Pharmacokinetics of Belinostat in Patients Who Have Mild, Moderate and Severe Renal Impairment.TerminatedPhase 1Acrotech Biopharma Inc.NCT02679131Written as Belinostat
- Belinostat and Carboplatin in Treating Patients With Recurrent or Persistent Ovarian Epithelial Cancer, Fallopian Tube Cancer, or Primary Peritoneal Cancer That Did Not Respond to Carboplatin or CisplatinCompletedPhase 2National Cancer Institute (NCI)NCT00993616Written as belinostat
See all 50 studies that test belinostat →
Given in every arm · 4 — belinostat is usual care beside what is tested
- Belinostat in Combination With Azacitidine or Pralatrexate for the Treatment of Relapse or Refractory T-cell LymphomaNot yet recruitingPhase 1City of Hope Medical CenterNCT07691450Written as Belinostat
- Direct Tumor Microinjection and FDG-PET in Testing Drug Sensitivity in Patients With Relapsed or Refractory Non-Hodgkin Lymphoma, Hodgkin Lymphoma, or Stage IV Breast CancerTerminatedPhase 1Mayo ClinicNCT03432741Written as Belinostat
- Extension Study for Patients Who Had Not Met Criteria for Discontinuation in Previous Sponsored Belinostat TrialsCompletedPhase 1Acrotech Biopharma Inc.NCT04184869Written as Belinostat
- Evaluating Safety & Efficacy Belinostat Combo w Nivo Alone & w Ipi in Patients w Treated Metastatic/Advanced Carcinomas w ARID1A Lof MutationWithdrawnPhase 1University of UtahNCT04315155Written as Belinostat
As the comparator · 2 — what is tested is compared with belinostat
- Soquelitinib vs Standard of Care in Participants With Relapsed/Refractory Peripheral T-cell Lymphoma Not Otherwise Specified, Follicular Helper T-cell Lymphomas, or Systemic Anaplastic Large-cell LymphomaRecruitingPhase 3Corvus Pharmaceuticals, Inc.NCT06561048Written as Belinostat
- Randomized Phase IIB Trial of Oral Azacytidine Plus Romidepsin Versus Investigator's Choice in PTCLRecruitingPhase 2University of VirginiaNCT04747236Written as Belinostat
Codes
What other systems call belinostat · ClinicalTrials.gg INT004656
- MeSH (NLM) C487081belinostatConfirmed ClinicalTrials.gov, NLM, Wikidata
- UNII (FDA) F4H96P17NZBELINOSTATConfirmed FDA, NLM, Wikidata
- RxNorm 1543543Confirmed FDA, Wikidata
- Wikidata Q4882925belinostatConfirmed FDA, NLM, Wikidata
- NCI Thesaurus C48812BelinostatConfirmed FDA, Wikidata
- DrugBank DB05015One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| MeSH (NLM) | C487081 | belinostat | Confirmed ClinicalTrials.gov, NLM, Wikidata |
| UNII (FDA) | F4H96P17NZ | BELINOSTAT | Confirmed FDA, NLM, Wikidata |
| RxNorm | 1543543 | — | Confirmed FDA, Wikidata |
| Wikidata | Q4882925 | belinostat | Confirmed FDA, NLM, Wikidata |
| NCI Thesaurus | C48812 | Belinostat | Confirmed FDA, Wikidata |
| DrugBank | DB05015 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.