Pancreatic Fistula clinical trials
The registry lists 122 studies for Pancreatic Fistula across more than 10 countries. 27 are recruiting or about to start. 92 of them are mainly about Pancreatic Fistula (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Who runs them
Azienda Ospedaliera Universitaria Integrata Verona (6) · Minia University (5) · Assiut University (5) · Peking Union Medical College Hospital (4) · Mansoura University (3) · Wakayama Medical University (3) · Assistance Publique - Hôpitaux de Paris (3) · Seoul National University Hospital (3)
What is being tested here
Drugs under test in Pancreatic Fistula studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Somatostatin | 0 | 1 | 2 |
| Hydrocortisone | 0 | 0 | 1 |
| Amoxicillin | 0 | 0 | 1 |
| Clavulanic Acid | 0 | 0 | 1 |
| Albumins human | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 8
- Dec 2026Prophylactic Abdominal Drainage vs no Drainage After Distal Pancreatectomy · Clinica Universidad de Navarra, Universidad de Navarra
- Dec 2026Peritoneal Lavage on the Incidence of Pancreatic Fistula and Related Complications After Pancreatoduodenectomy · Second Affiliated Hospital, School of Medicine, Zhejiang University
- Dec 2026Intrapapillary Botulinum Toxin Injection for PREvention of Post-surgical PAncREactic Fistula · Assistance Publique - Hôpitaux de Paris
- Jan 2027Indocyanine Green Fluorescence in Evaluation of Pancreatic Remnant Perfusion. · Charles University, Czech Republic
- Feb 2027Laparoscopic Pancreaticoduodenectomy · Minia University
- Mar 2027Immunoparalysis After Pancreaticoduodenectomy · Hospices Civils de Lyon
- Mar 2027Predictive Risk Factors for Pancreatic Fistula After Pancreaticoduodenectomy · Minia University
- Aug 2027Prevention of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy by Preoperative Radiotherapy : a Phase 2 Trial · Assistance Publique - Hôpitaux de Paris
Who these studies take
Of the 21 Pancreatic Fistula studies recruiting now, 13 (62%) set no upper age limit and 6 (29%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 20 (95%) | 20 (95%) |
| 30 | 20 (95%) | 20 (95%) |
| 40 | 20 (95%) | 20 (95%) |
| 50 | 21 (100%) | 21 (100%) |
| 65 | 21 (100%) | 21 (100%) |
| 75 | 21 (100%) | 21 (100%) |
| 85 | 15 (71%) | 15 (71%) |
Across all 122 studies, recruiting or not: 16% stop at 75 or younger and 2% at 65; 12% take children; 0% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pancreatic Fistula studies take
Of 22 observational studies under Pancreatic Fistula, half reached primary completion within 26 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Observational | 26 mo20–53 · 22 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 122. Browse all 122 → or search them.
- Laparoscopic PancreaticoduodenectomyRecruitingNCT07009119Not applicable1 country
- Predictive Risk Factors for Pancreatic Fistula After PancreaticoduodenectomyRecruitingNCT07022015Not applicable1 country
- Postoperative Pancreatic Fistula Following PancreaticoduodenectomyNot yet recruitingNCT07854353
- External Pancreatic Stent in PancreaticojejunostomyRecruitingNCT06743516Not applicable1 country
- Immunoparalysis After PancreaticoduodenectomyRecruitingNCT071449171 country
- Evaluation of the Perfusion of the Pancreatic Remnant With Indocyanine Green and Its Impact on the Reduction of Pancreatic Fistula After PancreaticoduodenectomyRecruitingNCT07502053Not applicable1 country
- Octreotide Microspheres for Preventing Pancreatic FistulaNot yet recruitingNCT07479784Phase 3
- Reinforced Pancreaticojejunostomy With or Without glubran2RecruitingNCT06756074Phase 21 country
- Pancreatic Head Resection or Total Pancreatectomy With Islet Autotransplantation in Patients With Periampullary Cancer and High Risk Profile for the Development of Postoperative Pancreatic FistulaRecruitingNCT05843877Phase 31 country
- Prevention of Postoperative Pancreatic Fistula Following Pancreaticoduodenectomy by Preoperative Radiotherapy : a Phase 2 TrialRecruitingNCT07370987Phase 21 country
- Compliance With ERAS Protocol in Pancreatic Surgery, Stress Response and OutcomesRecruitingNCT055186431 country
- Comparison of Three-sided and Single-sided Mattress Pancreaticojejunostomy in PancreatoduodenectomyEnrolling by invitationNCT06855888Not applicable1 country
- A Prospective Cohort Study on Ligation of Pancreatic Stump After Distal PancreatectomyEnrolling by invitationNCT06814249Not applicable1 country
- Assessing Pancreatic Fistula Rates After Distal Pancreatectomy Using AEON EndostaplerRecruitingNCT067641341 country
- Association Between Perioperative Blood and Interstitial Fluid Glucose Level and Clinically Relevant Postoperative Pancreatic Fistula in Different Pancreatic SurgeriesRecruitingNCT062895301 country
- METabolomic and Immune PROfiling in the Development of Pancreatic Fistulas After cepHalic duodEnopancreatectomyRecruitingNCT062831601 country
- Indocyanine Green Fluorescence in Evaluation of Pancreatic Remnant Perfusion.RecruitingNCT06198400Not applicable1 country
- Comparison of Effectiveness of TissuePatchTM in Preventing Postoperative Pancreatic FistulaRecruitingNCT05404256Not applicable1 country
- Prophylactic Abdominal Drainage vs no Drainage After Distal PancreatectomyNot yet recruitingNCT06141044Not applicable
- Influence of Pancreatic Transection With CUSA on Postoperative Pancreatic Fistula Incidence (PANCUT)RecruitingNCT06135012Not applicable1 country
- Intrapapillary Botulinum Toxin Injection for PREvention of Post-surgical PAncREactic FistulaRecruitingNCT04220931Not applicable1 country
- Peritoneal Lavage on the Incidence of Pancreatic Fistula and Related Complications After PancreatoduodenectomyNot yet recruitingNCT05657366Not applicable1 country
- A Multicenter Randomized Controlled Study of External Pancreatic Duct Stents in PancreaticoduodenectomyRecruitingNCT05725590Not applicable1 country
- Different Pancreaticojejunostomy After PancreaticoduodenectomyRecruitingNCT05475275Not applicable1 country
- Preoperative Endoscopic Pancreatic Stent for Distal PancreatectomyRecruitingNCT05297136Not applicable1 country
- Total pancrEaTectomy vs High-Risk Pancreatic anastomosiSRecruitingNCT05212350Not applicable2 countries
- Prognostic Factors in Periampullary Tumors and CystsRecruitingNCT051558781 country
- Preoperative EUS Elastography for Pancreatic Texture and POPF Prediction After PDCompletedNCT071392361 country
- Radiofrequency-assisted Transection of the Pancreas vs StaplerCompletedNCT04402346Not applicable1 country
- Internal Biodegradable Stent Versus Non-Stent in Patients at High-Risk of Developing Fistula After PancreatoduodenectomyCompletedNCT05668260Not applicable1 country
- PoLyglycolic Acid Felt reiNforcEmenT of the PancreaticoJejunostomy (PLANET-PJ Trial)CompletedNCT03331718Phase 31 country
- Monitoring of patIents With Microdialysis Following PancreaticoduodenectomyActive, not recruitingNCT03631173Not applicable1 country
- Study of Pancreatic Enzymes in the Drains as Early Biomarkers of Post-operative Pancreatic Fistula and Its Clinical RepercussionsCompletedNCT027849901 country
- Prevention of Postoperative Pancreatic Fistula by SomatostatinCompletedNCT03000946Phase 31 country
- Distal Pancreatectomy Pancreatic Fistula Risk Prediction Model Validation StudyCompletedNCT057378751 country
- The Novel Modified Cattell-Warren Duct-To-Mucosa Pancreaticojejunostomy Technique Significantly Reduces POPF.CompletedNCT070381611 country
- Intraoperative Biodegradable Stent Placement to Reduce Complications After PancreatoduodenectomyCompletedNCT06205693Not applicable1 country
- The Study of the Natural Way of Development of External Pancreatic Fistulas in Children with Necrotizing PancreatitisCompletedNCT067064401 country
- eXtended Antibiotic Prophylaxis for Intermediate- and High-risk Glands After Pancreatoduodenectomy to Reduce CR-POPFTerminatedNCT05753735Phase 21 country
- Clinically Relevant Pancreatic Fistula After PancreaticoduodenectomyCompletedNCT050172071 country
- Complication of Pancreatic Fistula and Bleeding After Pancreaticoduodenectomy in Treatment Periampullary CancerCompletedNCT049850711 country
- Predictors of Severity of Postoperative Pancreatic Fistula After PancreatoduodenectomyCompletedNCT052919231 country
- Postoperative Pancreatic Fistula in Patients Undergoing PancreaticoduodenectomyNo longer availableNCT063008011 country
- A Retrospective Analysis of Pancreatic Injuries and Treatment OutcomesCompletedNCT062278711 country
- Early Drain Removal Versus Standard Drain Management After Distal Pancreatectomy (Early-Dist)CompletedNCT04609137Not applicable1 country
- Clinical and Economic Validation of the ISGPS Definition of PPAPCompletedNCT056806231 country
- Effect of Trans-Nasal Afferent Loop Decompression on Post-Pancreaticoduodenectomy Pancreatic FistulaCompletedNCT04989868Not applicable1 country
- Risk Factors for Clinically Relevant Postoperative Pancreatic FistulaCompletedNCT056878251 country
- A Study on the Occurrence Time of Grade-B Pancreatic Fistula After PancreatoduodenectomyStatus unknownNCT056672721 country
- Comparison of Outcomes With Stapler Versus Hand-Sewn Closure After Minimally Invasive Distal PancreatectomyCompletedNCT057894591 country