Osteomyelitis clinical trials
The registry lists 105 studies for Osteomyelitis across more than 10 countries. 30 are recruiting or about to start. 62 of them are mainly about Osteomyelitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Who runs them
Hospices Civils de Lyon (6) · University of Texas Southwestern Medical Center (4) · Assistance Publique - Hôpitaux de Paris (3) · Biocomposites Ltd (3) · Cubist Pharmaceuticals LLC, a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (2) · BONESUPPORT AB (2) · Indiana University (2) · Rigshospitalet, Denmark (2)
What is being tested here
Drugs under test in Osteomyelitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 10
- Nov 2026Initial Oral Antibiotics for Bone and Joint Infections in Children · Rigshospitalet, Denmark
- Nov 2026Management of Medication Related Osteonecrosis of the Jaws With Double Periosteal Flap Closure · Tanta University
- Dec 2026Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections. · IRCCS San Raffaele
- Feb 2027FDG-PET Imaging in Complicated Diabetic Foot · University of Pennsylvania
- Mar 2027BonE and Joint Infections - Simplifying Treatment in Children Trial · Murdoch Childrens Research Institute
- Jun 2027Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA Infections · Indiana University
- Jul 2027Antibiotic Impregnated Beads in Osteomyelitis · University of Arizona
- Aug 2027A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers. · Biocomposites Ltd
- Oct 2027Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin. · Biocomposites Ltd
- Nov 2027Evaluation of the Efficiency of the Bone Substitute Cerament-G Locally Delivering Gentamicin in the Treatment of Chronic Osteomyelitis of Long Bones · Hospices Civils de Lyon
Who these studies take
Of the 22 Osteomyelitis studies recruiting now, 13 (59%) set no upper age limit and 7 (32%) stop at 75 or younger. 6 (27%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 6 (27%) | 6 (27%) |
| 18 | 18 (82%) | 18 (82%) |
| 30 | 16 (73%) | 16 (73%) |
| 40 | 16 (73%) | 16 (73%) |
| 50 | 16 (73%) | 16 (73%) |
| 65 | 16 (73%) | 16 (73%) |
| 75 | 16 (73%) | 16 (73%) |
| 85 | 15 (68%) | 15 (68%) |
Across all 105 studies, recruiting or not: 25% stop at 75 or younger and 22% at 65; 28% take children; 1% are for women only and 0% for men only; 2% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Osteomyelitis studies take
Of 21 interventional studies with no phase under Osteomyelitis, half reached primary completion within 42 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 42 mo24–69 · 21 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 105. Browse all 105 → or search them.
- A Randomized Controlled Phase II Trial of STIMULAN VG vs Standard of Care (SoC) for the Treatment of Osteomyelitis Associated With Stage IV Pressure Ulcers.RecruitingNCT06283979Phase 21 country
- Antibiotic Device for Osteomyelitis of the Extremities Pivotal Trial - Genex With Gentamicin.RecruitingNCT07270380Not applicable1 country
- BonE and Joint Infections - Simplifying Treatment in Children TrialRecruitingNCT04538053Phase 43 countries
- Population Pharmacokinetic Model of Rifampicin in Staphylococcal Osteoarticular InfectionsRecruitingNCT07788404Not applicable1 country
- Trimethoprim-sulfamethoxazole vs. Clindamycin for the Treatment of Children With Invasive MRSA InfectionsRecruitingNCT06982105Phase 41 country
- The ACHILLS Trial; Application of Cerament in Heel Infection for Lower Limb SalvageRecruitingNCT07057817Not applicable1 country
- EFFICACY AND SAFETY OF ZOLEDRONATE VERSUS PLACEBO ON PAIN AT WEEK 12 IN PEDIATRIC PATIENTS WITH CHRONIC RECURRENT MULTIFOCAL OSTEOMYELITISNot yet recruitingNCT07668583Phase 21 country
- Management of Medication Related Osteonecrosis of the Jaws With Double Periosteal Flap ClosureEnrolling by invitationNCT07177378Not applicable1 country
- Continuous Antibiotic Infusion In ChildrenRecruitingNCT07575009Phase 31 country
- CERAMENT G as Part of the Surgical Treatment of Osteomyelitis in a Single-Stage ProcedureRecruitingNCT065558481 country
- Comparison of Oral Antibiotics For Bone Infections of the Leg and FootRecruitingNCT07266753Phase 41 country
- Prospective, Randomized, Multicenter Clinical Trial of Bisphosphonates Combined With Vancomycin for the Treatment of Cierny-Mader Type I and III OsteomyelitisNot yet recruitingNCT07435051Phase 31 country
- Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections.Not yet recruitingNCT07426471
- Infrared Thermography for Diagnosis of Musculoskeletal InfectionsRecruitingNCT073880171 country
- Osteomyelitis Multi-center Prospective Cohort StudyNot yet recruitingNCT072513741 country
- Assessment of Non Vascular Risk Factors for Severity of Diabetic Foot Ulcers (DFUs)Not yet recruitingNCT07193992
- CERAMENT G Device RegistryRecruitingNCT060104331 country
- Antibiotic Impregnated Beads in OsteomyelitisNot yet recruitingNCT07072923Phase 4
- Monotherapy vs Combination Therapy for Bone Infections Caused by Pseudomonas AeruginosaRecruitingNCT070568811 country
- Initial Oral Antibiotics for Bone and Joint Infections in ChildrenRecruitingNCT068274961 country
- Additional Hyperbaric Oxygen After Lower Extremity AmputationRecruitingNCT03594344Not applicable1 country
- Fosfomycin I.v. for Treatment of Severely Infected PatientsRecruitingNCT029799515 countries
- Surgical Treatment of Osteoarticular Infections Using Bioactive Bone SubstituteNot yet recruitingNCT06402292Not applicable
- RCT on Bioactive Glass S53P4 in Diabetic Foot Osteomyelitis in the Forefoot (DFORCT)RecruitingNCT06388603Not applicable1 country
- SAVE- Oral Antibiotics for Treatment of Vertebral OsteomyelitisRecruitingNCT062500231 country
- Effect of Pulsed Electromagnetic Field Stimulation on Localized Pediatric OsteomyelitisRecruitingNCT06084754Not applicable1 country
- Don't Treat Ghosts Anti-MRSA Antibiotics in Osteomyelitis Without Identified MRSARecruitingNCT060960121 country
- T2MR PCR Detection of ESKAPE Pathogens in Patients With Pyogenic Spondylodiscitis and Infective EndocarditisRecruitingNCT056449901 country
- RETR(Osteomyelitis)RecruitingNCT049369581 country
- Treatment of Osteomyelitis-associated Pressure Ulcers by Surgical Flaps and Anti-bacterial AgentsRecruitingNCT057131491 country
- Acute Non-severe Osteomyelitis in Children - Outpatient Management Strategy With Oral Antibiotic Therapy Compared to a Standard Strategy With Conventional Hospitalization and Intravenous Antibiotic Therapy: a Randomized Open-label Non-inferiority Study With Bayesian and Medical-economic Analyses.Active, not recruitingNCT04554108Not applicable1 country
- A Feasibility Trial to Investigate the Safety and Between-group Effect Size of STIMULAN VG and Standard of Care (SoC) in Participants With Diabetic Foot OsteomyelitisCompletedNCT05539963Phase 21 country
- Evaluation of the Efficiency of the Bone Substitute Cerament-G Locally Delivering Gentamicin in the Treatment of Chronic Osteomyelitis of Long BonesActive, not recruitingNCT04805164Not applicable1 country
- Posterior Transforaminal Debridement and Fusion Without Costotransversectomy for Thoracic Pyogenic Vertebral OsteomyelitisCompletedNCT07817927Not applicable1 country
- Post Market Study of Cerament V/G in Pedal OsteomyelitisCompletedNCT06628115Not applicable1 country
- Retention and Re-Engagement in Treatment for Addiction Following Serious Injection Related Infections (RETAIN)CompletedNCT06489535Not applicable1 country
- Quasi-Randomized Evaluation of the UCLA Next Day Clinic (NDC)CompletedNCT06526884Not applicable1 country
- Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in DiabeticsCompletedNCT03012529Phase 41 country
- FDG-PET Imaging in Complicated Diabetic FootActive, not recruitingNCT001942981 country
- Evaluation of Outcomes of Surgical Treatment for Nonspecific Infectious Spondylodiscitis Via Posterior Approach in One Center.CompletedNCT07349602Not applicable1 country
- Pre-Surgery Rehab for a Child With Humeral Head and Shaft Deformity: A Case ReportCompletedNCT07283302Not applicable1 country
- Bacteriophage Therapy in Patients With Diabetic Foot OsteomyelitisTerminatedNCT05177107Phase 21 country
- Optimal Antibiotics for Operated Diabetic Foot InfectionsCompletedNCT04081792Not applicable1 country
- Oral-only Antibiotics for Bone and Joint Infections in ChildrenCompletedNCT04563325Phase 41 country
- Short or Long Antibiotic Regimes in OrthopaedicsCompletedNCT03806166Not applicable4 countries
- Efficacy of Oral vs IV Antibiotics in the Treatment of Orofacial OsteomyelitisStatus unknownNCT05867654Phase 41 country
- Antibiotic Therapy in Infections of the Diabetic Foot SyndromeCompletedNCT056163511 country
- Differentiation of Bone Sarcomas and Osteomyelitis With Ferumoxytol-Enhanced MRICompletedNCT01336803Phase 21 country
- Tolerability, Safety, and Efficacy of Tedizolid as Oral Treatment for Bone and Joint Infections (OTTER)CompletedNCT03009045Phase 21 country
- Next-Generation Sequencing for Pathogen Detection and Quantification in Children With Musculoskeletal InfectionsCompletedNCT03846804Not applicable1 country