Oropharyngeal Neoplasms: all 378 studies
Page 1 of 4. Open to participants first (99), then studies with results posted, then the rest; newest registration first within each.
- Off-line Adaptive Proton TherapyNot yet recruitingNCT07866547
- Intraoperative Methadone for the Management of Postoperative Pain in Patients With Head and Neck CancersRecruitingNCT07857655Phase 4
- Proactively Intervening On Early Cranial Nerve Injury As A Delayed Sequela Of Oropharyngeal Cancer: A Randomized Feasibility Clinical Trial For Pro-Habilitation (proNERVE RCT)Not yet recruitingNCT07832266Phase 1
- A Study to Evaluate CRB-701 Compared to Investigator's Choice Therapy in Previously Treated Oropharyngeal Squamous Cell CarcinomaRecruitingNCT07768189Phase 3
- HPV-associated Oropharyngeal Carcinoma (HPV-OPC)RecruitingNCT07718620Not applicable
- Thermotherapy for Head and Neck Cancer PatientsRecruitingNCT07690618Phase 1
- Ficerafusp Alfa, Pembrolizumab, and Stereotactic Body Radiotherapy (SBRT) for Head and Neck Squamous Cell Carcinoma (HNSCC)Not yet recruitingNCT07552558Phase 1/2
- Transoral and Cervical Ultrasound of Patients With Suspected Oropharyngeal CancerRecruitingNCT07548268Not applicable
- Impact of Postoperative Radiotherapy Versus PD-1 Inhibitor Maintenance on Survival in Resectable Locally Advanced Oral and Oropharyngeal Squamous Cell CarcinomaNot yet recruitingNCT07457099
- Comparing Radiation Plus Cetuximab to Radiation Plus Chemotherapy in People With Head and Neck Cancer Who Cannot Receive CisplatinRecruitingNCT07441681Phase 3
- A Single Arm Phase II Trial in p16-positive Oropharynx Cancer of Selective Dose De-escalation of nodAl VolumEs at Minimal Risk and Primary Site Disease (SAVED)Not yet recruitingNCT07418034Phase 2
- A Study Evaluating the Contribution of Non-Coplanar Beam Arrangement in Reducing Toxicity in Radiotherapy for Upper Aerodigestive Tract CancersNot yet recruitingNCT07413627Not applicable
- Surgery With or Without Neoadjuvant Treatment of SBRT Plus Chemoimmunotherapy in Resectable Locally Advanced Oral and HPV-unrelated Oropharyngeal Squamous Cell CarcinomaNot yet recruitingNCT07402538Phase 3
- Toripalimab in Combination With Standard Treatment for Human Papillomavirus (HPV) Positive Throat CancerRecruitingNCT07290621Phase 2
- SPECT-CT Guided ELEctive Contralateral Neck Treatment in Lateralized Oropharyngeal CancerNot yet recruitingNCT07241273Not applicable
- Neoadjuvant Chemotherapy and Programmed Cell Death Protein 1(PD-1) Inhibition for Head and Neck Cancer Treatment De-escalation (NeoScorch HN)RecruitingNCT07209189Phase 2
- Testing the Addition of Chemotherapy or Chemo-Immunotherapy to the Usual Surgery for Advanced Head and Neck CancerRecruitingNCT07195734Phase 2
- Evaluating a Decreased Dose of Radiation Therapy to the Elective Neck for the Treatment of HPV-Related Oropharyngeal Cancer, ENLIGHT TrialRecruitingNCT07178301Phase 2
- Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell CarcinomaRecruitingNCT07156227Phase 1
- A Study of Sacituzumab Govitecan in Combination With Cetuximab in People With Head and Neck Squamous Cell Cancer (HNSCC)RecruitingNCT07063212Phase 2
- Transmission of Oncogenic HPV Infection Among FamiliesNot yet recruitingNCT07036211
- Prevalence of Human Papillomavirus (HPV) in a Healthy Population: A Feasibility Study of Oropharyngeal Cancer ScreeningRecruitingNCT07033091Not applicable
- Methotrexate, Erlotinib, and Celecoxib for the Treatment of Recurrent/Metastatic Head and Neck Cancer in a Rural Midwest United States PopulationRecruitingNCT06997068Phase 2
- A Study of Reduced Radiation Therapy With Chemotherapy in People With HPV-Positive Throat CancerRecruitingNCT06984861Phase 2
- Buccal Fat for Transoral Robotic Lateral Oropharyngectomy Defects to and Postoperative PainNot yet recruitingNCT06965738Phase 2
- Comparing an Investigational Scan (F-18 NaF PET/CT) to Standard of Care Imaging (F-18 FDG PET/CT) for Evaluating Vascular Complications in Patients Receiving Radiation Therapy for Head and Neck CancerRecruitingNCT06914999Early Phase 1
- Treatment De-Escalation for Favorable Prognosis Human Papilloma Virus (HPV) or p16-Positive Oropharyngeal Cancer Receiving Definitive RadiotherapyRecruitingNCT06902623Not applicable
- TMV Vaccine Therapy Alone and With Pembrolizumab for the Treatment of Recurrent and/or Metastatic Head and Neck Squamous Cell CancerRecruitingNCT06868433Phase 1
- Patients With Human Papillomavirus-associated Head and Neck Cancer for the Discovery of Predictive Biomarkers to Guide Clinical InterventionRecruitingNCT06821243
- Intratumoral Lidocaine Injection Before Oropharyngeal Cancer SurgeryRecruitingNCT06747390Phase 1
- Lymphocyte-Sparing And Radio-Immunotherapy in Head and Neck CarcinomaRecruitingNCT06706401Phase 3
- The Minimalist Trial-2RecruitingNCT06702033Phase 2
- Enhancing Oral Cancer AwarenessRecruitingNCT06682494Not applicable
- Arabic PRO Measures for Head and Neck Cancer Radiotherapy.RecruitingNCT06662929
- Remote Audiometry to Monitor for Treatment-Related Hearing Loss in Patients With H&N SCC Receiving Cisplatin and/or RadiationRecruitingNCT06662058Not applicable
- Human Papillomavirus Association and Genomic Exploration in Head-Neck Squamous Cell CarcinomasRecruitingNCT06642324
- Lovastatin and Pembrolizumab for the Treatment of Patients With Recurrent or Metastatic Head and Neck Cancer, LAPP TrialRecruitingNCT06636734Phase 2
- Oncology, Undernutrition and Sensoriality: Links, Mechanisms and Levers for ActionRecruitingNCT06600295
- Personalized Volume-deescalated Elective Nodal Irradiation in Oropharyngeal Head and Neck Squamous Cell CarcinomaRecruitingNCT06563362Phase 2
- De-escalation of Adjuvant Radiation for Low-Risk HPV Oropharyngeal CancersRecruitingNCT06554158Not applicable
- Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck CancerRecruitingNCT06532279Phase 2
- PIRATES: Image-guided Hyper-fractioned Dose-escalation With Proton Therapy for Head and Neck CancerRecruitingNCT06446713Phase 1
- Using CircuLating Tumor DNA to Risk Adapt Post-Operative Therapy for HPV-associated Oropharyngeal CancerRecruitingNCT06445114Phase 2
- Oropharynx (OPX) Biomarker TrialRecruitingNCT06356272
- Adaptive De-intensified Radiotherapy Using Circulating Tumor DNA in HPV- Associated Oropharyngeal CancerRecruitingNCT06323460Phase 2
- A Study to Evaluate Lenti-HPV-07 Immunotherapy Against HPV+ Cervical or Oropharyngeal CancerRecruitingNCT06319963Phase 1/2
- Dose Adjusted Chemoradiotherapy in HPV-Associated Oropharynx Cancer of the ElderlyRecruitingNCT06309225Not applicable
- Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)RecruitingNCT06305676
- Pre-operative Atezolizumab in Patients With Resectable, Human Papillomavirus Related Oropharyngeal CarcinomaRecruitingNCT06254911Phase 2
- Phase II Trial of Neoadjuvant Chemotherapy (NAC) Alone or in Combination With Immunotherapy Vaccine PRGN-2009 in Subjects With Newly Diagnosed HPV-Associated Oropharyngeal (Head and Neck) CancerRecruitingNCT06223568Phase 2
- PD-1 Inhibitor Based Induction Chemotherapy Followed by De-escalation Protocols in OPSCCRecruitingNCT06156891Phase 2
- Standard Pulsed Radiofrequency Versus Supervoltage Pulsed Radiofrequency Glossopharyngeal Nerve in Oropharyngeal Cancer PainRecruitingNCT06121102Not applicable
- Real-time Targeted Fluorescence Endoscopy for Detection of the Primary Cancer Lesion in Patients With a Metastasis of Unknown Primary Tumor in the Head and NeckRecruitingNCT06100081Not applicable
- New Prognostic and Predictive Biomarkers for HPV-associated Oropharyngeal CancerRecruitingNCT06097936
- Selective Adjuvant Therapy for HPV-mediated Oropharynx SCCs Based on Residual Circulating Tumor DNA Levels (SAVAL)RecruitingNCT06088381Phase 2
- Immunological Function After Radiation With Either Proton or Photon TherapyRecruitingNCT06016699
- Single and Combined Modality Trans-Oral Robotic Surgery in Early Oropharyngeal CancerRecruitingNCT05933889
- A Phase II Study for p16+ Oropharyngeal Cancer PerSonalized De-escalation Treatment at University of MIchigan (CuSToMIze)RecruitingNCT05894083Phase 2
- Multidimensional and Multimodal Profiling of Oropharyngeal CarcinomaRecruitingNCT05880797
- Lymphoscintigraphy Directed Elective Neck Radiation for p16+ Favorable Risk Oropharynx CancerRecruitingNCT05800574Phase 2
- pBI-11 & TA-HPV (With Pembrolizumab as Treatment for Patients w/Advanced, PD-L1 CPS≥1, hrHPV+ Oropharyngeal CancerRecruitingNCT05799144Phase 2
- Multi-Site Trial of Navigation vs Treatment as Usual to Improve Initiation of Timely Adjuvant TherapyRecruitingNCT05793151Not applicable
- HRYZ-T101 TCR-T Cell for HPV-18 Positive Advanced Solid TumorRecruitingNCT05787535Phase 1
- Role of Liquid Biopsies in HPV-associated Cancer Treatment MonitoringRecruitingNCT05774561
- Evaluation of the Benefit of a New Surgical Procedure According to IDEAL Recommendations for ORL Cancer Patients: the External Pudendal Flap Used as a New Free Flap for Oral Cavity/Oropharyngeal Reconstruction to Limit Donor Site SequelaeRecruitingNCT05757817Not applicable
- Tolerance and Benefits of Mandibular Advanced Device for Snoring and Sleep Apnea in Oropharyngeal Cancer.RecruitingNCT05719779Not applicable
- E7 TCR-T Cell Immunotherapy for Human Papillomavirus (HPV) Associated CancersRecruitingNCT05686226Phase 2
- E7 T-cell Receptor (TCR) -T Cell Induction Therapy for Locoregionally Advanced HPV-associated CancersRecruitingNCT05639972Phase 1/2
- Autologous T Cells Targeting HPV16 HPV18 & Survivin in Patients With R/R HPV-related Oropharyngeal CancersNot yet recruitingNCT05582590Phase 1
- De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNARecruitingNCT05541016Phase 2
- A Study of Reduced Radiation Therapy and Standard-of-Care Chemotherapy in People With HPV-Positive Throat CancerRecruitingNCT05491512Phase 2
- SPECT-CT Guided ELEctive Contralateral Neck Treatment for Patients With Lateralized Oropharyngeal CancerRecruitingNCT05451004Phase 3
- Transoral Surgical Resection Followed by De-escalated Adjuvant IMRT in Resectable p16+ Locally Advanced Oropharynx CancerRecruitingNCT05388773Phase 2
- Immune Biomarker Study for Head and Neck CancerRecruitingNCT05375266
- Special Care Patterns for Elderly HNSCC Patients Undergoing RadiotherapyRecruitingNCT05337631
- A Study on Using Cell-Free Tumor DNA (ctDNA) Testing to Decide When to StartRoutine Treatment in People With Human Papilloma Virus (HPV)- Associated Oropharynx Cancer (OPC)RecruitingNCT05307939Phase 2
- Bitter Taste Receptors in Oropharynx CancerRecruitingNCT05211427Not applicable
- Testing the Addition of Ipatasertib to Usual Chemotherapy and Radiation for Head and Neck CancerRecruitingNCT05172245Phase 1
- Surgery Vs Chemoradiation for Oropharyngeal Cancer- A Phase II/III Integrated Design Randomized Control TrialNot yet recruitingNCT05144100Phase 2/3
- BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot StudyRecruitingNCT05136196Phase 2
- Adaptive RadioTherapy for OroPharynx CancerRecruitingNCT04901234Phase 2
- Risk-adapted Therapy in HPV+ Oropharyngeal Cancer Using Circulating Tumor (ct)HPV DNA Profile - The ReACT StudyRecruitingNCT04900623Phase 2
- Toripalimab Based Induction Chemotherapy Followed by De-escalation Protocols in HPV-related OPSCCRecruitingNCT04867330Not applicable
- Task of Acoustic-phonetic Decoding on Anatomic Deficits in Paramedical Assessment of Speech Disorders for Patients Treated for Oral or Oropharyngeal CancerRecruitingNCT04742998
- Lymphatic Mapping Of Oropharyngeal CancerRecruitingNCT04498221Not applicable
- Testing Less Intensive Radiation With Chemotherapy to Treat Low-risk Patients With HPV-positive Oropharyngeal CancerRecruitingNCT04444869Phase 2
- Neoadjuvant Chemotherapy and Transoral Robotic Surgery for Oropharyngeal Cancer.RecruitingNCT04277858Phase 2
- Gene Therapy Follow up Protocol for Subjects Previously Enrolled in NCI Center for Immuno-Oncology StudiesEnrolling by invitationNCT04266093
- Study of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)RecruitingNCT04198766Phase 1/2
- Stereotactic Boost and Short-course Radiation Therapy for Oropharynx CancerRecruitingNCT04178174Phase 3
- High Dose Steroid Therapy (Prednisone or Methylprednisolone) for the Improvement of Symptoms of Late Radiation-Associated Lower Cranial Neuropathy in Oropharyngeal Cancer SurvivorsRecruitingNCT04151082Phase 1/2
- p16+ Oropharyngeal Cancer Radiation Optimization Trial Reducing Elective Treatment Volumes (PROTEcT)RecruitingNCT04104945Not applicable
- Assessment of Swallowing Function and Quality of Life in Oropharyngeal Cancer Patients Treated by Chemo-radiotherapyRecruitingNCT04019548Phase 3
- De-escalation of Adjuvant Radio (Chemo) Therapy for HPV-positive Head-neck Squamous Cell CarcinomasRecruitingNCT03396718Not applicable
- Adaptive Treatment De-escalation in Favorable Risk HPV-Positive Oropharyngeal CarcinomaRecruitingNCT03215719Phase 2
- Blood Tests and Questionnaires in Studying Adherence to Preventative Swallowing Exercises in Participants With Metastatic Head and Neck CancerRecruitingNCT03010150
- Integrated Cancer Repository for Cancer ResearchRecruitingNCT02012699
- Association Between Health Care Provider (HCP)-Assessed ECOG Performance Status (PS) and Overall Survival, and Objectively Measure of Physical Activity (PA) Levels in Advance-cancer Patients"RecruitingNCT01365169Not applicable
- Biomarkers in Patients With Respiratory Tract Dysplasia or Lung Cancer, Head and Neck Cancer, or Aerodigestive Tract Cancer and in Normal VolunteersRecruitingNCT00900419
- A Vaccine (PDS0101) Alone or in Combination With Pembrolizumab for the Treatment of Locally Advanced Human Papillomavirus-Associated Oropharynx CancerActive, not recruitingNCT05232851Phase 1/2Results posted