ClinicalTrials.gg
RecruitingNCT05880797Updated Sep 15, 2026

Multidimensional and Multimodal Profiling of Oropharyngeal Carcinoma

An observational study in Oropharyngeal Carcinoma and Human Papilloma Virus, sponsored by Stanford University. Recruiting at 1 site in United States. Open to participants aged 18 Years and older. Per ClinicalTrials.gov, last updated 2026-09-15.

Sponsored by Stanford University · Observational

From the registry’s dates

  • Started Jul 2023; still recruiting 3 years 4 months later.

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Study type
Observational
Model
Cohort
Time perspective
Prospective
Enrollment
1,000
Ages
18 Years and older
Sex
All
01

Where this study stands

Counted across the records on this site · 2026-11-14

Among 233 studies in Oropharyngeal Neoplasms with a site in United States — 61 open to participants now, 96 under way, 10 of them phase 3. Oropharyngeal Neoplasms · United States.

Planned enrollment
6th of 35
1,000 · median 185
Started
2023
with 14 others
Observational
35 of 233
8 open now
Primary completion
2027-08
later than 42 of 95 live
Registered
194th of 233
by date

Among the 233 studies in Oropharyngeal Neoplasms with a site in United States, this one is the 6th largest by planned enrollment of the 35 observational ones that give a count, is one of 15 that started in 2023, is one of 35 observational ones, reaches primary completion later than 42 of the 95 other live ones, and was the 194th registered.

Oropharyngeal Neoplasms

369 studies on the registry are indexed under Oropharyngeal Neoplasms; 103 are open to participants now.

Browse Oropharyngeal Neoplasms studies →

Open to participants now

61 of the 233 studies in Oropharyngeal Neoplasms with a site in United States are open now. Recruiting first, the newest first:

56 more — sign in →

All 61 open studies →

A study can be open while its sites in United States have not opened yet or have stopped. Only those recruiting at a site in United States →

Who these studies take

Of the 89 Oropharyngeal Neoplasms studies recruiting now, 76 (85%) set no upper age limit and 5 (6%) stop at 75 or younger; none take children under 18; 7 take healthy volunteers.

This study: 18 Years and older · all sexes · no healthy volunteers.

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02

Study summary

The purpose of this study is to better understand the natural history of oropharyngeal carcinoma (OPC), with or without an association with the human papilloma virus (HPV). For this study, the investigators plan to collect blood from OPC patients prior to treatment and at six subsequent time points.

03

Conditions studied

  • Oropharyngeal Carcinoma
  • Human Papilloma Virus
04

Who can participate

Ages eligible
18 Years and older
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

Participants with known or suspected oropharyngeal carcinoma. All patients with OPC getting surgery at Stanford are invited to participate in the study.

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Patients diagnosed with oropharyngeal carcinoma or patients with cancer of the unknown primary that is HPV associated, or possibly deemed to be originating from the oropharynx.

Exclusion criteria

Exclusion Criteria:

  • Not willing to sign consent
05

Study design

Observational model
Cohort
Time perspective
Prospective
Enrollment
1,000 participants (estimated)
Patient registry
No
Biospecimen retention
Samples with dna
06

What researchers measure

Primary outcomes

  1. Sample collection

    30-50cc of blood

    Time frame: prior to start of treatment

  2. Sample collection

    30-50cc of blood

    Time frame: up to 36 months post-op

Secondary outcomes

  1. tumor sample

    tumor sample (FFPE) or fresh tissue post-excision or surgery, this will only be collected, if and when feasible, after the tumor has been removed post procedure.

    Time frame: Day 1

07

Study locations

1 of 1 sites recruiting
08

Timeline

Tracking since Sep 25, 2026
ElapsedEstimatedEstimated, not yet reachedSimilar studies: half by the dot; the band is the middle halfHalf of similar studies reached it by the dot; the band is the middle half, from a quarter to three quarters

Started Jul 2023 (actual). Primary completion is estimated for Aug 2027, 49 months after the start.

Of 47 observational studies under Oropharyngeal Neoplasms, half reached primary completion within 110 months of starting (the median), counting those still running; a quarter within 40. This study's planned 49 months is below that.

How these figures are worked out, and which studies are left out of them.

Registered
May 17, 2023
First posted
May 30, 2023
StartActual
Jul 7, 2023
Primary completionEst.
Aug 2027
CompletionEst.
Aug 2027
Last update
Sep 15, 2026
What these dates mean
Start.
When the first participant enrolled; while estimated, when the study expects to open to recruitment.
Primary completion.
When the last participant was examined or treated to collect data for the study's main question, its primary outcome. A study that stopped early gives the date its data collection stopped.
Completion.
When the last participant's last visit took place, for every outcome, secondary ones and side effects included: the end of the study. Often later than primary completion, sometimes the same day.
Actual and Est.
Actual means the registry says the date has happened. Est. (estimated) is a date the sponsor plans or expects. It can still move, and the sponsor is expected to change it to actual once it has passed.
No changes since tracking began. The registry record was last updated on Sep 15, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
09

Registry details

Key details

Study ID
NCT05880797
Responsible party
Sponsor
First posted
May 30, 2023
Start date
Jul 7, 2023
Primary completion
Aug 2027 (estimated)
Completion
Aug 2027 (estimated)
Last update
Sep 15, 2026

Study contacts

Nikita Bedi
Contact
nbedi@stanford.edu
(650) 723-5957
Chris Holsinger, MD
principal investigator · Stanford University

Oversight

FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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