Ocular Hypertension: all 659 studies

Page 1 of 7. Open to participants first (48), then studies with results posted, then the rest; newest registration first within each.

• Changes in Intraocular Pressure After Intravitreal InjectionNot yet recruitingNCT07826286
• iDose TR Administration in an Office-Based Surgery SettingRecruitingNCT07816692
• Eplerenone and IOP in Healthy AdultsNot yet recruitingNCT07795762Phase 1
• REGN22530 for Adults With Primary Open Angle Glaucoma or Ocular HypertensionRecruitingNCT07675824Phase 1/2
• [KJ-TFC-005] Phase 3 Study, Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-Angle Glaucoma or Ocular HypertensionRecruitingNCT07662759Phase 3
• A Study to Evaluate Efficacy and Safety of YSBP Compared to Lumigan in Patients With Glaucoma or Ocular HypertensionRecruitingNCT07661329Phase 3
• Evaluation of the Safety, Efficacy, Dose Response of the Bimatoprost Drug Ring System (BIM-DRS) in Pseudophakic Patients Diagnosed With Open Angle Glaucoma or Ocular HypertensionNot yet recruitingNCT07641296Phase 1
• Efficacy and Safety of DNN.31.19.026 for Ocular Hypertension or Primary Open-Angle GlaucomaNot yet recruitingNCT07617532Phase 3
• Imaging the Effects of Netarsudil (Rhopressa) on the Trabecular Meshwork in Glaucoma and Ocular HypertensionRecruitingNCT07588152Phase 4
• Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral ImplantRecruitingNCT07495852Phase 3
• Direct vs Standard SLT for Glaucoma: A Noninferiority TrialRecruitingNCT07408154Not applicable
• Observational Trial of the Updated Inserter for the Travoprost Intracameral Implant 75mcgRecruitingNCT07400926
• DSLT for Reducing Medication in GlaucomaRecruitingNCT07390890
• Efficacy and Safety of HUC3-637 in Patients With Primary Open Angle Glaucoma or Ocular HypertensionRecruitingNCT07335211Phase 3
• 24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension PatientsRecruitingNCT07325240Phase 4
• A Comparative Study of Intraocular Pressure Control Using Selective Laser Trabeculoplasty and Latanoprost as Initial Treatments for Primary Open Angle Glaucoma and Ocular Hypertension in Lagos State University Teaching HospitalRecruitingNCT07310719Not applicable
• Automated Applanation Tonometry - UpdatedRecruitingNCT07298356Not applicable
• Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)RecruitingNCT07218796Phase 3
• Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)RecruitingNCT07218783Phase 3
• Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication UseRecruitingNCT07217678Phase 4
• GLAUcoma Diagnostic and Imaging Analysis (GLAUDIA) StudyNot yet recruitingNCT07210216
• Association Between Limbal Function and Tear Proteomics in Chronic Ocular Diseases: Focusing on GlaucomaRecruitingNCT07119580
• A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma PatientsRecruitingNCT07076303
• Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral ImplantRecruitingNCT07075718Phase 2
• Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract SurgeryRecruitingNCT07036510Phase 1/2
• Safety and Efficacy of iDose® TR With Cataract Surgery vs. Cataract Surgery AloneRecruitingNCT06848946Phase 4
• Long-term Vascular, Functional and Morphological Changes in Glaucoma and Ocular Hypertensive PatientsEnrolling by invitationNCT06827535
• Analysis of Risk Factors for High Intraocular Pressure and Retinal Detachment Recurrence After Vitrectomy with Silicone Oil Tamponade in Retinal Detachment PatientsRecruitingNCT06826573
• Long-term Safety and Efficacy of a Modified Suprachoroidal Silicone Tube (SST) ShuntRecruitingNCT06691555
• Implementing AI-based Glaucoma Screening Within Federally Qualified Health CentersRecruitingNCT06629649Not applicable
• Efficacy of NSAID vs. Steroid-NSAID Combo Post-Selective Laser Trabeculoplasty: Phase 4, Single-Center RCTNot yet recruitingNCT06498440Phase 4
• The A D A G I O StudyNot yet recruitingNCT06455683
• CLAD Deconvolved PERG Responses in Glaucoma PatientsRecruitingNCT06388096Not applicable
• A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both EyesRecruitingNCT06267274Phase 1
• A Randomized, Open-label, Active-controlled, Phase 2a Clinical Trial to Evaluate the Efficacy and Safety of TFC-003 in Patients With Primary Open-angle Glaucoma or Ocular HypertensionNot yet recruitingNCT06177678Phase 2
• Travoprost Ophthalmic Topical Cream for Open-angle Glaucoma or Ocular HypertensionRecruitingNCT06152861Phase 2
• Know Your Pressures NYCNot yet recruitingNCT05992415Not applicable
• High Intraocular Pressure After Cataract SurgeryNot yet recruitingNCT05834465
• Bioequivalence Study With Clinical Endpoint Comparing Bimatoprost Ophthalmic Solution 0.01% and LUMIGAN® in the Treatment of Chronic Open-Angle Glaucoma or Ocular Hypertension in Both Eyes.RecruitingNCT05401357Phase 3
• Use of Nanodropper vs. Standard Eyedropper in Patients With Glaucoma and Ocular HypertensionRecruitingNCT05277870Not applicable
• Optimal Treatment Protocol for Selective Laser Trabeculoplasty - Repeat TrialEnrolling by invitationNCT05159960Not applicable
• Inflammatory Biomarkers in Ocular Surface in Primary Open Angle Glaucoma or Ocular Hypertension Under Topical ProstaglandinsRecruitingNCT05039684
• Clarifying the Optimal Application of SLT Therapy TrialRecruitingNCT04967989Phase 3
• Effect of Benzalkonium Chloride Preserved and Preservative-free Latanoprost Eye Drops on Conjunctival Goblet CellsRecruitingNCT04957329Phase 4
• Measuring the Effects of Netarsudil, Latanoprost, and Combination Therapy on Episcleral and Retinal Blood Flow in Ocular Hypertension and Glaucoma SuspectsRecruitingNCT04401982Phase 4
• Endoscopic Assisted Anterior Hyaloid Peeling in Boston Type 1 Keratoprosthesis (KPro-HP-Endo)RecruitingNCT04337944Not applicable
• Intraocular Pressure Measured by a Novel Sensing Contact Lens Versus TonometryRecruitingNCT04024293Not applicable
• Investigation of Neurovascular Coupling in Glaucoma Patients and Healthy SubjectsRecruitingNCT03870230Not applicable
• A Study to Evaluate the Clinical Performance of VeriSee GLC for Screening of Glaucoma Suspect Using Color Fundus ImagesCompletedNCT07550712Results posted
• Performance of the Travoprost Intraocular ImplantCompletedNCT06582732Phase 2Results posted
• Efficacy and Safety Assessment of T4090 Ophthalmic Solution Versus Rhopressa® Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular HypertensionCompletedNCT06394973Phase 2Results posted
• Ph2 Placebo-Controlled Study for Safety & Ocular Efficacy of SBI-100 Ophthalmic Emulsion in Pts w/ Elevated Eye PressureCompletedNCT06144918Phase 2Results posted
• Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT05913232Phase 2Results posted
• Comfortable and Stabilizing Chin & Forehead Rest Attachment for Slit Lamp ConfigurationsTerminatedNCT05686421Not applicableResults posted
• A Study to Evaluate the Efficacy and Safety of OTX-TIC (Travoprost) Intracameral Implant for Patients With Open-angle Glaucoma (OAG) or Ocular Hypertension (OHT)CompletedNCT05335122Phase 2Results posted
• Efficacy of the Nanodropper Device on Intraocular Pressure in Patients With GlaucomaTerminatedNCT05273385Not applicableResults posted
• Automated Applanation TonometryTerminatedNCT05235321Not applicableResults posted
• A Therapeutic Equivalence Study in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT05022004Phase 3Results posted
• Safety and Intraocular Lowering Effect of Delivery of Travoprost Evolute® in Subjects With Elevated Intraocular PressureCompletedNCT04962009Results posted
• To Compare the Efficacy and Safety of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both EyesCompletedNCT04944290Phase 3Results posted
• Nebivolol 0.5, 1.0, or Timolol 0.5 Suspension Compared to Timolol 0.5 Solution to Treat Glaucoma/Ocular HypertensionCompletedNCT04910100Phase 2Results posted
• Study of LL-BMT1 in Patients With Elevated Intraocular PressureCompletedNCT04747808Phase 2Results posted
• Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT04742283Phase 2Results posted
• Comparative Study of the Efficacy of Either Krytantek Ofteno PF® or Eliptic Ofteno PF® Plus Gaap Ofteno PF® for POAG or Ocular Hypertension.TerminatedNCT04702789Phase 4Results posted
• Reliability and Reproducibility of the Eye Check TonometerTerminatedNCT04639947Not applicableResults posted
• Efficacy and Safety Study of Netarsudil 0.02% Ophthalmic Solution Compared to Ripasudil Hydrochloride Hydrate 0.4% Ophthalmic Solution in Japanese Subjects With Primary Open Angle Glaucoma or Ocular HypertensionCompletedNCT04620135Phase 3Results posted
• Phase 3 Trial of NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT04445519Phase 3Results posted
• Intraocular Pressure in Ocular Hypertensives With Scleral Lens WearTerminatedNCT04442464Not applicableResults posted
• Study to Assess the Efficacy, Safety and Tolerability of AKB-9778 Ophthalmic Solution as and Adjunct to Latanoprost in Patients With Ocular Hypertension or Open Angle GlaucomaCompletedNCT04405245Phase 2Results posted
• CLN-0045: Safety, and Efficacy of OTX-TIC in Participants With Open Angle Glaucoma or Ocular HypertensionCompletedNCT04360174Phase 1Results posted
• A Phase 3b Study Evaluating the 24-Hour Intraocular Pressure Lowering Effect of Bimatoprost SR in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT04285580Phase 3Results posted
• Safety and IOP-Lowering Effects of WB007CompletedNCT04149899Phase 1/2Results posted
• A Phase III Multinational Multicenter Investigator-Masked Randomized Active-Controlled Trial Comparing the Efficacy and Safety of DE-130A With Xalatan® in Patients With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT04133311Phase 3Results posted
• To Compare the Safety and Efficacy of Perrigo's Product to an FDA Approved Product for the Treatment of Glaucoma or Ocular Hypertension in Both EyesCompletedNCT04024072Phase 3Results posted
• Safety and Efficacy of Ophthalmic Phentolamine Mesylate in GlaucomaCompletedNCT03960866Phase 2Results posted
• Therapeutic Equivalence Study of Generic Brinzolamide vs AzoptCompletedNCT03896633Phase 1/2Results posted
• Clinical Study Comparing Two Models of a Travoprost Intraocular ImplantCompletedNCT03868124Phase 3Results posted
• Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Once Daily and Twice Daily in Subjects With Primary Open-Angle Glaucoma SPECTRUM 6CompletedNCT03858894Phase 2Results posted
• Efficacy and Systemic Safety of Netarsudil 0.01%, 0.02%, 0.04% Relative to Placebo in Subjects With Open-angle Glaucoma or Ocular Hypertension in JapanCompletedNCT03844945Phase 2Results posted
• Efficacy and Safety Assessment of T4032 Versus Lumigan® in Ocular Hypertensive or Glaucomatous PatientsCompletedNCT03825380Phase 3Results posted
• Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world SettingCompletedNCT03808688Phase 4Results posted
• DE-117 Spectrum 5 StudyCompletedNCT03697811Phase 3Results posted
• A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 4 StudyCompletedNCT03691662Phase 3Results posted
• A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 StudyCompletedNCT03691649Phase 3Results posted
• Phase 2 Dose-Response Study Evaluating the Safety and Efficacy of NCX 470 vs Latanoprost in Subjects With Open-Angle Glaucoma or Ocular HypertensionCompletedNCT03657797Phase 2Results posted
• Randomized Study Comparing Two Models of a Travoprost Intraocular Implant to Timolol Maleate Ophthalmic Solution, 0.5%CompletedNCT03519386Phase 3Results posted
• Evaluation of Safety and Efficacy of PDP-716CompletedNCT03450629Phase 3Results posted
• Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular HypertensionCompletedNCT03310580Phase 2Results posted
• Safety and Efficacy Study of PG324 (Netarsudil/Latanoprost 0.02% / 0.005%) Ophthalmic Solution Compared to GANFORT® Ophthalmic Solution in Open Angle Glaucoma or Ocular HypertensionCompletedNCT03284853Phase 3Results posted
• Non-inferiority of PRO-122 Ophthalmic Solution vs KRYTANTEK Ofteno® in Glaucoma or Ocular Hypertension (CONFORTK)CompletedNCT03257813Phase 3Results posted
• Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)CompletedNCT03233308Phase 2Results posted
• A Phase IIb Safety and Efficacy Study of DE-126 Ophthalmic Solution in Primary Open-Angle Glaucoma or Ocular Hypertension- Angel StudyCompletedNCT03216902Phase 2Results posted
• Brinzolamide/Brimonidine Combination vs Brimonidine 0.2% in the Prevention of IOP Rise After Nd-YAG Laser CapsulotomyCompletedNCT03192826Phase 4Results posted
• Treatment Outcomes of MicroPulse Trans-scleral Cyclophotocoagulation in Uncontrolled GlaucomaCompletedNCT03187418Not applicableResults posted
• Study of SHP639 Eye Drops in Adults With High Eye Pressure or Primary Open-angle GlaucomaCompletedNCT03131167Phase 1Results posted
• Effect of Alternate Therapies on Intraocular Pressure in Ocular HypertensionCompletedNCT02993445Not applicableResults posted
• A Phase III Study Assessing the Safety and Efficacy of DE-117 Ophthalmic Solution Compared With Latanoprost Ophthalmic Solution in Subjects With OAG or OHTCompletedNCT02981446Phase 3Results posted
• Phase 3 Study Evaluating Safety and Efficacy of OTX-TP in Subjects With OAG or OHTCompletedNCT02914509Phase 3Results posted
• Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic SolutionCompletedNCT02874846Phase 2Results posted
• Study of Fixed-Dose Combinations of Trabodenoson and Latanoprost in Adults With OHT or POAGCompletedNCT02829996Phase 2Results posted

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