Neuroinflammatory Diseases clinical trials
The registry lists 180 studies for Neuroinflammatory Diseases across more than 10 countries. 80 are recruiting or about to start. 24 of them are mainly about Neuroinflammatory Diseases (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-10.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
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Status
Who runs them
National Institute of Mental Health (NIMH) (9) · Assistance Publique - Hôpitaux de Paris (5) · Leiden University Medical Center (3) · Karolinska University Hospital (2) · Centre Hospitalier St Anne (2) · Ain Shams University (2) · Penn State University (2) · Bayer (2)
What is being tested here
Drugs under test in Neuroinflammatory Diseases studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Dexmedetomidine | 2 | 0 | 3 |
| Minocycline | 1 | 1 | 3 |
| Immunoglobulins, Intravenous | 1 | 0 | 2 |
| Immunoglobulin G | 1 | 0 | 2 |
| Orelabrutinib | 1 | 0 | 1 |
| Norethindrone Acetate | 1 | 0 | 1 |
| Norethindrone | 1 | 0 | 1 |
| Elagolix | 1 | 0 | 1 |
| Ascorbic Acid | 1 | 0 | 1 |
| Palmidrol | 1 | 0 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 2 open · NSAIDs 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Nov 2026Inflammatory and Infectious Diseases of the Nervous System · National Institute of Neurological Disorders and Stroke (NINDS)
- Nov 2026Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH) · Johns Hopkins University
- Nov 2026Effectiveness of Neuroplasticity-Targeted Supplements on Neuroinflammatory Markers, ADHD Symptom Severity, and Clinical Scores in Children · Khyber Medical University Peshawar
- Dec 2026Palmitoylethanolamide and Luteolin in Patients with Acute Ischemic Stroke · Ospedali Riuniti Trieste
- Dec 2026Accelerated iTBS for Major Depression · Istanbul University - Cerrahpasa
- Dec 2026Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2 · National Institute of Neurological Disorders and Stroke (NINDS)
- Dec 2026Effect of Tocopherol and Ascorbic Acid on Neuroinflammation Markers Associated With Neuropeptide Expression in the AgRP/NPY and POMC Pathways in Mexican Population With Obesity · Autonomous University of Morelos
- Dec 2026Using Light Therapy for Mild Cognitive Impairment · University of Oklahoma
- Dec 2026Inflammatory faCtors AfteR acUte Ischemic Stroke · Martin Dichgans
- Jan 2027IMPACT-D+: Immune-Modulating and Psychometric Effects of Accelerated TMS in Depression Plus Comorbid Post-COVID-19 Condition · Max-Planck-Institute of Psychiatry
Who these studies take
Of the 53 Neuroinflammatory Diseases studies recruiting now, 16 (30%) set no upper age limit and 24 (45%) stop at 75 or younger. 11 (21%) take children under 18. 1 (2%) are for women only and 2 (4%) for men only; 17 (32%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 11 (21%) | 11 (21%) |
| 18 | 30 (57%) | 32 (60%) |
| 30 | 30 (57%) | 32 (60%) |
| 40 | 33 (62%) | 33 (62%) |
| 50 | 39 (74%) | 39 (74%) |
| 65 | 42 (79%) | 42 (79%) |
| 75 | 32 (60%) | 32 (60%) |
| 85 | 23 (43%) | 23 (43%) |
Across all 180 studies, recruiting or not: 44% stop at 75 or younger and 30% at 65; 13% take children; 4% are for women only and 5% for men only; 38% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Neuroinflammatory Diseases studies take
Of 34 interventional studies with no phase under Neuroinflammatory Diseases, half reached primary completion within 27 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 27 mo23–44 · 34 studies | — | — |
| Observational | 51 mo13–84 · 34 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered4
- Neurogenetics and Multi-omics of Neuroinflammatory Diseases in Multiplex Families to Improve Patients HealthOct 28, 2026NCT07902479
- A Longitudinal Natural History Study of Immune Biomarkers in Neuropsychiatric IllnessOct 16, 2026NCT07877246
- Safety, Tolerability, and Pharmacodynamic Exploration of Orelabrutinib in Patients With Amyotrophic Lateral Sclerosis (ALS)Oct 15, 2026NCT07875972
- Tau Pathology in the Brain After Hip or Knee Replacement SurgeryOct 13, 2026NCT07871487
Studies
Recruiting first, then most recently updated. Showing 50 of 180. Browse all 180 → or search them.
- Immunotherapy for Neurological Post-Acute Sequelae of SARS-CoV-2Enrolling by invitationNCT05350774Phase 21 country
- Inflammatory and Infectious Diseases of the Nervous SystemRecruitingNCT024358101 country
- Safety, Tolerability, and Pharmacodynamic Exploration of Orelabrutinib in Patients With Amyotrophic Lateral Sclerosis (ALS)Not yet recruitingNCT07875972Phase 1
- Neurogenetics and Multi-omics of Neuroinflammatory Diseases in Multiplex Families to Improve Patients HealthNot yet recruitingNCT07902479Not applicable1 country
- A Trial to Test the Use of Dapansutrile, an Anti-inflammatory Medication, in People With Parkinson's DiseaseRecruitingNCT07157735Phase 21 country
- Minocycline In Neurocognitive Outcomes - Sickle Cell DiseaseNot yet recruitingNCT05605366Phase 1
- A Longitudinal Natural History Study of Immune Biomarkers in Neuropsychiatric IllnessRecruitingNCT078772461 country
- A Phase 2a Study of SUN-627 in Participants With Non-Active Secondary Progressive and Primary Progressive Multiple Sclerosis (SPMS/PPMS)RecruitingNCT07840326Phase 21 country
- The BANYAN Trial, an ALS MyMatch Trial Evaluating Safety, Biomarker Activity, and Microglial Activation of Nasal ForalumabEnrolling by invitationNCT07688239Phase 21 country
- Tau Pathology in the Brain After Hip or Knee Replacement SurgeryRecruitingNCT078714871 country
- Exploratory Study of Low-Dose Whole-Brain Radiation Therapy With HeLaXON 1X in Patients With Mild Alzheimer's Disease DementiaRecruitingNCT07863011Not applicable1 country
- IMPACT-D+: Immune-Modulating and Psychometric Effects of Accelerated TMS in Depression Plus Comorbid Post-COVID-19 ConditionRecruitingNCT07197138Not applicable1 country
- Auricular Vagus Nerve Stimulation Mechanisms for HIV-Associated Peripheral NeuropathyRecruitingNCT07822932Not applicable1 country
- Using Glialia for Treating Persistent Perceptual Postural DizzinessRecruitingNCT06741358Phase 41 country
- Perioperative Biomarkers and Postoperative Delirium in Older Adults Undergoing Abdominal Cancer SurgeryRecruitingNCT078594881 country
- [11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection FractionNot yet recruitingNCT07856043Phase 11 country
- Hyperbaric Oxygen Therapy for Veterans With TBI and PCS: A Biomarker StudyRecruitingNCT07849465Phase 21 country
- Vancomycin Study in Multiple Sclerosis (MS)RecruitingNCT05539729Phase 11 country
- A Study of Psychedelics in Healthy Older Adults With Low Well-beingRecruitingNCT07386730Phase 11 country
- Translocator Protein PET/CT in Various TSPO-Related DiseaseRecruitingNCT067257191 country
- Snacks and Brain HealthRecruitingNCT07348406Phase 1/21 country
- Longitudinal Profiling of Plasma-Derived Glial Extracellular Vesicles in Alzheimer's DiseaseRecruitingNCT07803055Not applicable1 country
- Comprehensive Approach to Lifestyle Modification in Chronic MigraineNot yet recruitingNCT07802860Not applicable1 country
- Brain and Blood Vessel Health Following Endometriosis Treatment in People With EndometriosisNot yet recruitingNCT07799246Phase 4
- Effect of Tocopherol and Ascorbic Acid on Neuroinflammation Markers Associated With Neuropeptide Expression in the AgRP/NPY and POMC Pathways in Mexican Population With ObesityNot yet recruitingNCT07782411Not applicable1 country
- Prednisone in Adults With an Immune-Mediated Subtype of Autism Spectrum DisorderRecruitingNCT06934915Early Phase 11 country
- Brain Imaging and Immune Changes During Remibrutinib Treatment in Multiple Sclerosis.RecruitingNCT077582701 country
- Therapeutic Approach of Repeated Transient Blood-brain Barrier Opening in Amyotrophic Lateral Sclerosis.RecruitingNCT07571486Phase 1/21 country
- Detection and Characterization of Neurologic Manifestations of Inborn and Acquired Errors of ImmunityRecruitingNCT061691501 country
- Biomarkers for Diagnosis and Treatment Response in Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)RecruitingNCT077189581 country
- Retinal OCT Changes and Biomarkers in Drug-Resistant EpilepsyEnrolling by invitationNCT077169301 country
- Palmitoylethanolamide/Luteolin Supplementation in Older Adults Undergoing Cardiac SurgeryNot yet recruitingNCT07681063Not applicable1 country
- Intra-Articular Adelmidrol 2%/Hyaluronic Acid 1% With or Without m/umPEA, in Knee Pain Due to Joint Degeneration.Not yet recruitingNCT07680101Not applicable1 country
- CIRP and Cathepsin B in Neuroinflammation After Intracerebral HemorrhageNot yet recruitingNCT07665255
- Effectiveness of Neuroplasticity-Targeted Supplements on Neuroinflammatory Markers, ADHD Symptom Severity, and Clinical Scores in ChildrenRecruitingNCT07665658Not applicable1 country
- Perioperative Argon Inhalation to Improve Neurocognitive Recovery After Carotid SurgeryRecruitingNCT07200180Phase 31 country
- Using Light Therapy for Mild Cognitive ImpairmentRecruitingNCT07651787Not applicable1 country
- Accelerated iTBS for Major DepressionRecruitingNCT07603804Not applicable1 country
- Targeting Neuroinflammation as a Contributing Pathology in Alzheimer's Disease Dementia and Related DementiasEnrolling by invitationNCT04786223Phase 21 country
- Healthy Eating and Active Living for People Living With Multiple Sclerosis (HEAL MS): A Lifestyle Program for People With Multiple SclerosisNot yet recruitingNCT07589062Not applicable1 country
- Vitamin D3 for Moderate to Mild Traumatic Brain Injury: A Randomized Trial on Inflammation and Recovery (VIMOT)RecruitingNCT07269457Phase 21 country
- Effects of Cannabidiol and Tetrahydrocannabinol on Microbiome and Neuroinflammation in HIVRecruitingNCT05514899Phase 21 country
- Study of Axial and Cognitive Symptoms and Biomarkers of Neurodegeneration in Brain-first and Body-first PDRecruitingNCT071878431 country
- Effects of a 6-months Fiber- and Polyphenol-rich Diet on Brain Inflammatory Processes in Perimenopausal Women Living With Overweight or ObesityRecruitingNCT07501377Not applicable1 country
- Tinnitus and Treatment With umPEA-LUTNot yet recruitingNCT06718452Not applicable1 country
- Neuroinflammatory Biomarkers After General Anesthesia: A Comparison StudyNot yet recruitingNCT07388160
- Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation ResearchRecruitingNCT048066201 country
- TaVNS for Acute Intracerebral HemorrhageRecruitingNCT06918964Not applicable1 country
- Female Concussion Head CoolingNot yet recruitingNCT07303933Not applicable1 country
- Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional StudyRecruitingNCT069738371 country