Paraparesis, Tropical Spastic clinical trials

The registry lists 23 studies for Paraparesis, Tropical Spastic across 6 countries. 2 are recruiting or about to start. 19 of them are mainly about Paraparesis, Tropical Spastic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Status

Completed: 14
Terminated: 4
Status unknown: 3
Recruiting: 2

Phase

Phase 2: 7
Phase 3: 6
Early Phase 1: 2
Phase 1: 2
Phase 4: 1

Where

United States: 9
Brazil: 5
United Kingdom: 3
Japan: 3
Peru: 1
China: 1

Who runs them

National Institute of Neurological Disorders and Stroke (NINDS) (6) · MP Biomedicals, LLC (3) · Imperial College London (3) · Hospital Universitário Professor Edgard Santos (2) · Kyowa Kirin Co., Ltd. (1) · Mitsubishi Tanabe Pharma Corporation (1) · St. Marianna University School of Medicine (1) · Universidad Peruana Cayetano Heredia (1)

What is being tested here

Drugs under test in Paraparesis, Tropical Spastic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

Drug	Phase 3	All
Valproic Acid	1	2
Unasnemab	0	1
Raltegravir	0	1
Cyclosporine	1	1
Zidovudine	1	1
Lamivudine	1	1
Anti-CD122 Humanized Monoclonal Antibody Mik-Beta-1	0	1
Pentoxifylline	1	1
Tamibarotene	1	1
Mogamulizumab	1	1

Who these studies take

Of the 2 Paraparesis, Tropical Spastic studies recruiting now, 1 (50%) set no upper age limit and 0 (0%) stop at 75 or younger. 0 (0%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (50%) take healthy volunteers.

Recruiting studies that take each age, of 2
Age	Women	Men
10	0 (0%)	0 (0%)
18	2 (100%)	2 (100%)
30	2 (100%)	2 (100%)
40	2 (100%)	2 (100%)
50	2 (100%)	2 (100%)
65	2 (100%)	2 (100%)
75	2 (100%)	2 (100%)
85	2 (100%)	2 (100%)

Across all 23 studies, recruiting or not: 22% stop at 75 or younger and 0% at 65; 22% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

Studies

Recruiting first, then most recently updated. Showing 23 of 23. search them.