Carcinoma, Medullary clinical trials
The registry lists 144 studies for Carcinoma, Medullary across more than 10 countries. 30 are recruiting or about to start. 64 of them are mainly about Carcinoma, Medullary (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Status
Who runs them
National Cancer Institute (NCI) (20) · M.D. Anderson Cancer Center (8) · Genzyme, a Sanofi Company (6) · Exelixis (4) · Eli Lilly and Company (4) · Sanofi (3) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (3) · European Organisation for Research and Treatment of Cancer - EORTC (3)
What is being tested here
Drugs under test in Carcinoma, Medullary studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Anlotinib | 1 | 1 | 2 |
| Lutetium Lu 177 dotatate | 1 | 0 | 2 |
| Enfortumab vedotin | 1 | 0 | 1 |
| AMG 757 | 1 | 0 | 1 |
| Gallium Ga 68 dotatate | 1 | 0 | 1 |
| Catequentinib hydrochloride | 1 | 0 | 1 |
| Cabozantinib | 0 | 1 | 8 |
| Vandetanib | 0 | 1 | 8 |
| Selpercatinib | 0 | 1 | 5 |
| Sorafenib | 0 | 0 | 5 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 2 open · Alkylating agents 5 · Antimetabolites 4 · mTOR inhibitors 4 · Angiogenesis inhibitors 3
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001) · Shanghai Jiao Tong University School of Medicine
- Dec 2026Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer Survivors · University of Southern California
- Dec 2026Database Linkage Study to Evaluate the Risk of Medullary Thyroid Carcinoma · Novo Nordisk A/S
- Apr 2027177Lu-PP-F11N for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer. · University Hospital, Basel, Switzerland
- Jun 2027A Comparison of [68Ga]DOTATATE and [18F]AmBF3TATE for the Staging and Assessment of Neuroendocrine Malignancies · British Columbia Cancer Agency
- Jun 2027Study of Anlotinib in Patients With Advanced Medullary Thyroid Carcinoma · Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
- Jun 2027Study of SNH-118110 in Advanced Solid Tumors · ScinnoHub Pharmaceutical Co., Ltd.
- Jun 2027Stromal Desmoplastic Reaction as a Predictive Factor for Lymph Node Metastasis in Medullary Thyroid Cancer · Aristotle University Of Thessaloniki
- Aug 2027Cancer and Blood Pressure Management, CARISMA Study · ECOG-ACRIN Cancer Research Group
- Nov 2027Trial of Lu-177 DOTATATE (Lutathera®) in Unlicensed Indications · University College, London
Who these studies take
Of the 16 Carcinoma, Medullary studies recruiting now, 9 (56%) set no upper age limit and 3 (19%) stop at 75 or younger. 3 (19%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 3 (19%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (19%) | 3 (19%) |
| 18 | 16 (100%) | 16 (100%) |
| 30 | 16 (100%) | 16 (100%) |
| 40 | 16 (100%) | 16 (100%) |
| 50 | 16 (100%) | 16 (100%) |
| 65 | 16 (100%) | 16 (100%) |
| 75 | 16 (100%) | 16 (100%) |
| 85 | 12 (75%) | 12 (75%) |
Across all 144 studies, recruiting or not: 8% stop at 75 or younger and 6% at 65; 17% take children; 0% are for women only and 0% for men only; 3% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 14, 2026.
Newly registered1
Studies
Recruiting first, then most recently updated. Showing 50 of 144. Browse all 144 → or search them.
- 68Ga-labeled Cholecystokinin Receptor (CCK2R) Targeted Molecular Probes in Early Tumor DiagnosisRecruitingNCT079147641 country
- STAGE-MTC Trial Thyroid Lobectomy With Ipsilateral Central Neck DissectionNot yet recruitingNCT07612293Not applicable1 country
- 211At-MABG in Adults With Advanced Neuroendocrine CancersNot yet recruitingNCT07661420Phase 11 country
- Enfortumab Vedotin for the Treatment of Unresectable or Metastatic Radioiodine Refractory Differentiated Thyroid Cancer, Anaplastic Thyroid Cancer, Medullary Thyroid Cancer, or NUT CarcinomaNot yet recruitingNCT07863765Phase 21 country
- A Comparison of [68Ga]DOTATATE and [18F]AmBF3TATE for the Staging and Assessment of Neuroendocrine MalignanciesNot yet recruitingNCT076211461 country
- Radiation Combined With BIspecific T-Cell Engager in DLL3 Expressing TumorsRecruitingNCT06814496Phase 1/21 country
- Stromal Desmoplastic Reaction as a Predictive Factor for Lymph Node Metastasis in Medullary Thyroid CancerNot yet recruitingNCT07851324
- Cultural Adaptation of an Educational Tool in Medullary Thyroid CancerRecruitingNCT071420051 country
- Natural History of Medullary Thyroid Cancer to Inform Advanced Disease ManagementRecruitingNCT042167321 country
- Phase II Trial of Sacituzumab Tirumotecan in Patients With SMARCB1-Deficient Renal Medullary CarcinomaRecruitingNCT07438626Phase 21 country
- Phase I Study of [225Ac]Ac-ETN029 in Patients With Advanced DLL3-expressing Solid TumorsRecruitingNCT07006727Phase 14 countries
- Thyroid Health Outcomes Registry for SurgeryNot yet recruitingNCT07812779
- Database Linkage Study to Evaluate the Risk of Medullary Thyroid CarcinomaEnrolling by invitationNCT077139011 country
- Patient Decision Aid in Supporting Decision-Making About When to Start or Stop New Drugs, Join Clinical Trials, or Continue Active Surveillance in Patients With Medullary Thyroid Cancer and Their CaregiversRecruitingNCT03892993Not applicable1 country
- Study of SNH-118110 in Advanced Solid TumorsNot yet recruitingNCT07649200Phase 11 country
- Treatment of Advanced Endocrine Tumor With Iindividualized mRNA Neoantigen Vaccine (mRNA-0523-L001)RecruitingNCT06141369Not applicable1 country
- CTR-FAPI-guided Precision Surgery for Newly Diagnosed MTCRecruitingNCT07383246Phase 31 country
- Research on the Application of 68Ga-DOTA-CCK-FS PET/CT in MTCRecruitingNCT07138716Not applicable1 country
- A Prospective Cohort Study of Pralsetinib or Anlotinib in the Treatment of Locally Advanced and/or Metastatic Medullary Thyroid Carcinoma With RET Gene MutationsNot yet recruitingNCT07048964
- PET-TC in Thyroid EvaluationEnrolling by invitationNCT068521441 country
- Genetic Bases of Neuroendocrine Neoplasms in Mexican PatientsRecruitingNCT065235821 country
- Head-to-head Study of 68Ga-MGS5 Versus 68Ga-DOTATATE PET/CT in Patients With Medullary Thyroid CarcinomaRecruitingNCT06520319Phase 11 country
- 68Ga-TCR-FAPI PET/CT Guided Precision Surgery for MTCRecruitingNCT06277180Not applicable1 country
- A Study of TY-1091 in Patients With Advanced Solid TumorsRecruitingNCT05675605Phase 1/21 country
- Trial of Lu-177 DOTATATE (Lutathera®) in Unlicensed IndicationsNot yet recruitingNCT06121271Phase 2
- A Detailed Look At What Patients Experience In Medullary Thyroid Cancer Clinical StudyNot yet recruitingNCT060797231 country
- Study of Anlotinib in Patients With Advanced Medullary Thyroid CarcinomaRecruitingNCT05830500Phase 41 country
- An Active Surveillance Program for Cases of Medullary Thyroid Carcinoma (MTC)Enrolling by invitationNCT015113931 country
- Study of Clinical Outcomes of Thyroid CancerRecruitingNCT040313391 country
- Amyloid Proteins From Medullary Thyroid Cancer and Laryngeal AmyloidosisNot yet recruitingNCT04760171
- Natural History Study of Children and Adults With Medullary Thyroid CancerActive, not recruitingNCT016609841 country
- Selpercatinib Before Surgery for the Treatment of RET-Altered Thyroid CancerActive, not recruitingNCT04759911Phase 21 country
- A Study of Two Different Doses of Cabozantinib (XL184) in Progressive, Metastatic Medullary Thyroid CancerActive, not recruitingNCT01896479Phase 414 countries
- Determining the Biodistribution of an Imaging Tracer (68Ga-FAPi-46) in Patients With Solid Tumors or Hematologic CancersActive, not recruitingNCT07118176Phase 11 country
- Social Health, Activity Behaviors, and Quality of Life Among Young Adult Cancer SurvivorsActive, not recruitingNCT072593041 country
- Copper Cu 64 Anti-CEA Monoclonal Antibody M5A PET in Diagnosing Patients With CEA Positive CancerActive, not recruitingNCT02293954Not applicable1 country
- Thermal Ablation of Cervical Metastases From Thyroid CarcinomaCompletedNCT04522570Not applicable1 country
- Cancer and Blood Pressure Management, CARISMA StudyActive, not recruitingNCT04467021Not applicable1 country
- Cabozantinib-S-Malate in Treating Younger Patients With Recurrent, Refractory, or Newly Diagnosed Sarcomas, Wilms Tumor, or Other Rare TumorsActive, not recruitingNCT02867592Phase 21 country
- A Study of Selpercatinib (LY3527723) in Participants With Advanced Solid Tumors Including RET Fusion-positive Solid Tumors, Medullary Thyroid Cancer and Other Tumors With RET ActivationActive, not recruitingNCT04280081Phase 21 country
- GFRα4 CAR T Cells in MTC PatientsActive, not recruitingNCT04877613Phase 11 country
- Prospective Study Evaluating the Medullary Thyroid Cancer Management's Care Using PET F-DOPA in Patients With a High Level of Postoperative Residual ThyrocalcitoninCompletedNCT02856347Not applicable1 country
- Testing the Combination of the Anti-cancer Drugs XL184 (Cabozantinib) and Nivolumab in Patients With Advanced Cancer and HIVActive, not recruitingNCT04514484Phase 11 country
- DOTATOC PET/CT for Imaging NET PatientsActive, not recruitingNCT035835281 country
- 177Lu-PP-F11N for Receptor Targeted Therapy and Imaging of Metastatic Thyroid Cancer.Active, not recruitingNCT02088645Phase 11 country
- Study to Determine if Contacting Patients With MTC More Frequently Results in Earlier Detection and Treatment of Signs and Symptoms of AEs and Thus a Decrease in the Percentage of Time Patients Experience AEs During First 12 Months on Vandetanib TreatmentCompletedNCT01298323Phase 320 countries
- A Study of Selpercatinib (LOXO-292) in Participants With Advanced Solid Tumors, RET Fusion-Positive Solid Tumors, and Medullary Thyroid Cancer (LIBRETTO-001)Active, not recruitingNCT03157128Phase 1/216 countries
- A Study of Selpercatinib (LY3527723) in Participants With RET-Mutant Medullary Thyroid CancerActive, not recruitingNCT04211337Phase 320 countries
- A Study of Oral LOXO-292 (Selpercatinib) in Pediatric Participants With Advanced Solid or Primary Central Nervous System (CNS) TumorsActive, not recruitingNCT03899792Phase 1/211 countries
- To Compare The Effects Of Two Doses Of Vandetanib In Patients With Advanced Medullary Thyroid CancerCompletedNCT01496313Phase 49 countries