Pheochromocytoma clinical trials
The registry lists 158 studies for Pheochromocytoma across more than 10 countries. 57 are recruiting or about to start. 91 of them are mainly about Pheochromocytoma (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.
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Status
Who runs them
National Cancer Institute (NCI) (15) · Peking Union Medical College Hospital (11) · Seoul National University Hospital (5) · Molecular Insight Pharmaceuticals, Inc. (5) · M.D. Anderson Cancer Center (4) · University of California, San Francisco (3) · British Columbia Cancer Agency (3) · Jagiellonian University (3)
What is being tested here
Drugs under test in Pheochromocytoma studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Drug classes tested here Immune checkpoint inhibitors 3 open · Tyrosine kinase inhibitors (TKIs) 2 open · Alkylating agents 1 open · PARP inhibitors 1 open · mTOR inhibitors 4
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The 10 nearest
- Dec 2026In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and Paraganglioma · Heather Wachtel
- Jan 2027Study of Axitinib (AG-013736) With Evaluation of the VEGF-pathway in Pheochromocytoma/Paraganglioma · Columbia University
- Jan 202718F-Fluorodopamine PET Studies of Neuroblastoma and Pheochromocytoma · St. Jude Children's Research Hospital
- Mar 2027LAnreotide in Metastatic Pheochromocytoma / PARAganglioma (LAMPARA) · Antonio Fojo
- Apr 2027An Experimental Study of Belzutifan Impact on Catecholamine Metabolism · Cambridge University Hospitals NHS Foundation Trust
- May 2027Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or Paraganglioma · Memorial Sloan Kettering Cancer Center
- May 2027Anlotinib Combined With Benmelstobart for Advanced Pheochromocytoma · Sun Yat-sen University
- Jun 2027A Comparison of [68Ga]DOTATATE and [18F]AmBF3TATE for the Staging and Assessment of Neuroendocrine Malignancies · British Columbia Cancer Agency
- Jun 2027Using the EHR to Advance Genomic Medicine Across a Diverse Health System · University of Pennsylvania
- Aug 2027The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive Pheochromocytoma · Seoul National University Hospital
Who these studies take
Of the 43 Pheochromocytoma studies recruiting now, 22 (51%) set no upper age limit and 6 (14%) stop at 75 or younger. 19 (44%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 4 (9%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 14 (33%) | 14 (33%) |
| 18 | 41 (95%) | 41 (95%) |
| 30 | 42 (98%) | 42 (98%) |
| 40 | 42 (98%) | 42 (98%) |
| 50 | 42 (98%) | 42 (98%) |
| 65 | 42 (98%) | 42 (98%) |
| 75 | 40 (93%) | 40 (93%) |
| 85 | 33 (77%) | 33 (77%) |
Across all 158 studies, recruiting or not: 16% stop at 75 or younger and 4% at 65; 35% take children; 0% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Pheochromocytoma studies take
Of 28 phase 2 interventional studies under Pheochromocytoma, half reached primary completion within 92 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 2 | 92 mo36–157 · 28 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
What changed recently
From the registry's own updates since Oct 13, 2026.
Started recruiting1
Newly registered2
- Adrenal Diseases in the Population of Modena: A Clinical-Epidemiological Database of Patients Referred to the Adrenal Disorders Outpatient Clinic of the Clinical Unit of Endocrinology at the Modena University Hospital (AOU Modena)Nov 5, 2026NCT07920198
- Safety and Efficacy of Belzutifan in Preoperative Preparation for Patients With Pheochromocytoma/Paraganglioma (PPGL)Oct 30, 2026NCT07907341
Studies
Recruiting first, then most recently updated. Showing 50 of 158. Browse all 158 → or search them.
- Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)RecruitingNCT04924075Phase 222 countries
- A First-in-Human Phase I Trial With Antibody Drug Conjugate ADCT-701 in Neuroendocrine Tumors, Carcinomas and Malignant Peripheral Nerve Sheath TumorsRecruitingNCT06041516Phase 11 country
- Adrenal Diseases in the Population of Modena: A Clinical-Epidemiological Database of Patients Referred to the Adrenal Disorders Outpatient Clinic of the Clinical Unit of Endocrinology at the Modena University Hospital (AOU Modena)RecruitingNCT079201981 country
- Genetic Analysis of Pheochromocytomas, Paragangliomas and Associated ConditionsRecruitingNCT031602741 country
- Von Hippel-Lindau (VHL): Clinical Manifestations, Diagnosis, Management and Molecular Bases of Inherited Renal and Other Urologic Malignant DisordersRecruitingNCT000012381 country
- Safety and Efficacy of Belzutifan in Preoperative Preparation for Patients With Pheochromocytoma/Paraganglioma (PPGL)RecruitingNCT07907341Phase 41 country
- 18F-Fibroblast Activation Protein Inhibitor ([18F]FAPI-74) PET Imaging for Cancer DetectionRecruitingNCT06503146Phase 21 country
- Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ ParagangliomaRecruitingNCT03206060Phase 21 country
- Cardiovascular Complications After Adrenalectomy for Pheochromocytoma and Non-secreting TumorsRecruitingNCT072002451 country
- Somatostatin-Receptors (SSTR)-Agonist [212Pb]VMT-alpha-NET in Metastatic or Inoperable SSTR+ Gastrointestinal Neuroendocrine Tumor and Pheochromocytoma/Paraganglioma Previously Treated With Systemic Targeted Radioligand TherapyRecruitingNCT06427798Phase 1/21 country
- Targeted Alpha-Particle Therapy for Advanced Somatostatin Receptor Type 2 (SSTR2) Positive TumorsRecruitingNCT05636618Phase 1/21 country
- Diagnosis of PheochromocytomaRecruitingNCT00004847Phase 11 country
- 211At-MABG in Adults With Advanced Neuroendocrine CancersNot yet recruitingNCT07661420Phase 11 country
- [212Pb]VMT-Alpha-NET in Metastatic or Inoperable Somatostatin-Receptor Positive Gastrointestinal Neuroendocrine Tumors, Pheochromocytoma/Paragangliomas, Small Cell Lung, Renal Cell, and Head and Neck CancersRecruitingNCT06479811Phase 11 country
- A Comparison of [68Ga]DOTATATE and [18F]AmBF3TATE for the Staging and Assessment of Neuroendocrine MalignanciesNot yet recruitingNCT076211461 country
- HTL0039732 in Participants With Advanced Solid TumoursRecruitingNCT05944237Phase 1/21 country
- STOMP OUT: A Phase 2 Study To Evaluate The Effects Of Ivonescimab In Patients With Unresectable/Metastatic Adrenocortical Carcinoma (ACC) Or Unresectable Pheochromocytoma/Paraganglioma (PPGL)Not yet recruitingNCT07743138Phase 21 country
- Project: Every Child for Younger Patients With CancerRecruitingNCT024022446 countries
- Using the EHR to Advance Genomic Medicine Across a Diverse Health SystemRecruitingNCT06377033Not applicable1 country
- A Compassionate Use/Expanded Access Protocol Using 131I-MIBG Therapy for Patients With Refractory Neuroblastoma and Metastatic PheochromocytomaAvailableNCT030158441 country
- Zanzalintinib in Unresectable and Progressive MPGGsNot yet recruitingNCT07714551Phase 21 country
- Italian Multicenter Experience With Radioreceptor-assisted Therapy (PRRT)Not yet recruitingNCT075387911 country
- An Experimental Study of Belzutifan Impact on Catecholamine MetabolismRecruitingNCT07680205Phase 21 country
- Familial Investigations of Childhood Cancer PredispositionRecruitingNCT030502681 country
- Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).RecruitingNCT06607692Phase 1/21 country
- Iodine I 131 Metaiodobenzylguanidine in Treating Patients With Recurrent, Progressive, or Refractory Neuroblastoma or Malignant Pheochromocytoma or ParagangliomaRecruitingNCT00107289Phase 21 country
- Adrenal Tumors - Pathogenesis and TherapyRecruitingNCT006692661 country
- Prospective Cohort Study of Pheochromocytoma/ParagangliomaNot yet recruitingNCT07516275
- Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid TumorsRecruitingNCT04119024Phase 11 country
- In Vivo PARP-1 Expression With 18F-FluorThanatrace PET/CT in Patients With Pheochromocytoma and ParagangliomaRecruitingNCT05636540Early Phase 11 country
- Institutional Registry of Rare DiseasesRecruitingNCT065737231 country
- Multicenter Study on Cardiovascular and Metabolic Complications in Patients With Biochemically Silent Pheochromocytomas and ParagangliomasEnrolling by invitationNCT073160751 country
- Al18F-NOTA-LM3 PET/CT in Patients With Pheochromocytoma and ParagangliomaRecruitingNCT07288931Not applicable1 country
- Clinical Application of Somatostatin Receptor and Norepinephrine Transporter Targeted Imaging for Diagnosis and Staging of Neuroblastoma and Pheochromocytoma/ParagangliomaRecruitingNCT071955001 country
- Comparative Study of Perioperative Cardiac Injury in Patients With Functional Adrenal TumorsEnrolling by invitationNCT071821751 country
- Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL TrialRecruitingNCT07167329Phase 21 country
- Ivonescimab in the Treatment of Multiple Advanced TumorsRecruitingNCT06683846Phase 21 country
- 18F-mFBG PET Imaging in the Evaluation of PheochromocytomaRecruitingNCT068137421 country
- The Effect and Safety of Omitting Preoperative Alpha-adrenergic Blockade for Normotensive PheochromocytomaRecruitingNCT05702944Phase 41 country
- Anlotinib Combined With Benmelstobart for Advanced PheochromocytomaNot yet recruitingNCT06429397Phase 21 country
- National Study of Adrenal TumoursEnrolling by invitationNCT068703961 country
- Hereditary Pheochromocytoma Assessment of Tumour ImmunologiesRecruitingNCT064446071 country
- "Receptor Radionuclide Therapy With 177Lu-DOTATOCRecruitingNCT06045260Phase 21 country
- Genetic Bases of Neuroendocrine Neoplasms in Mexican PatientsRecruitingNCT065235821 country
- The Incidence and Outcomes of Metabolically Active Brown Adipose Tissue (aBAT) in Patients With Pheochromocytoma or Paraganglioma (PPGLs)RecruitingNCT064401221 country
- Development of Clinical Evidence for Optimal Management of Adrenal Diseases Based on Real-World DataRecruitingNCT062294051 country
- 18F-MFBG PET/CT in the Evaluation of Neural Crest TumorRecruitingNCT05069220Early Phase 11 country
- Surgical Treatment of Adrenal Diseases- Laparoscopic vs. Robotic-assisted AdrenalectomyRecruitingNCT060500571 country
- Genetic Factors and Pheochromocytomas in Neoplasia Type 2RecruitingNCT051587121 country
- The Efficacy and Safety of Penpulimab in the Treatment of Metastatic PPGL Patients Who Fail to Other Systemic TreatmentRecruitingNCT05885399Phase 21 country