Nerve Sheath Neoplasms clinical trials
The registry lists 15 studies for Nerve Sheath Neoplasms across 8 countries. 8 are recruiting or about to start. 3 of them are mainly about Nerve Sheath Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-03. Counting its 9 narrower conditions too, such as Neurofibromatosis 1: 503 studies, 124 open.
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Who runs them
University of Florida (3) · National Cancer Institute (NCI) (3) · Robert Flavell, MD, PhD (1) · National Cheng-Kung University Hospital (1) · Maastricht Radiation Oncology (1) · Emory University (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins (1)
What is being tested here
Drugs under test in Nerve Sheath Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Pazopanib | 1 | 1 | 2 |
| Zirconium-89 | 1 | 0 | 1 |
| Selinexor | 1 | 0 | 1 |
| Zoledronic Acid | 1 | 0 | 1 |
| Luvometinib | 1 | 0 | 1 |
| Tazemetostat | 0 | 0 | 1 |
| Nivolumab | 0 | 0 | 1 |
| Ipilimumab | 0 | 0 | 1 |
| Doxorubicin | 0 | 1 | 1 |
| Ifosfamide | 0 | 1 | 1 |
Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open
Who these studies take
Of the 7 Nerve Sheath Neoplasms studies recruiting now, 4 (57%) set no upper age limit and 2 (29%) stop at 75 or younger. 4 (57%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (43%) | 3 (43%) |
| 18 | 7 (100%) | 7 (100%) |
| 30 | 6 (86%) | 6 (86%) |
| 40 | 5 (71%) | 5 (71%) |
| 50 | 5 (71%) | 5 (71%) |
| 65 | 5 (71%) | 5 (71%) |
| 75 | 5 (71%) | 5 (71%) |
| 85 | 5 (71%) | 5 (71%) |
Across all 15 studies, recruiting or not: 20% stop at 75 or younger and 20% at 65; 53% take children; 7% are for women only and 0% for men only; 7% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 15 of 15. search them.
- Surveillance for Malignant Transformation of Neurofibromatosis Type 1 (NF1) Related Peripheral Nerve Sheath Tumors (PNST)RecruitingNCT062222031 country
- Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncologyRecruitingNCT046484621 country
- Imaging Study of [89Zr]DFO-YS5 for Cancer DetectionRecruitingNCT07664397Phase 11 country
- NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)RecruitingNCT06239272Phase 1/21 country
- Alpha/Beta T and B Cell Depletion With Zoledronic Acid for Solid TumorsRecruitingNCT06625190Phase 1/21 country
- Hypofractionated Proton Therapy for Benign Intracranial Brain Tumors, the HiPPI StudyRecruitingNCT04278118Not applicable1 country
- Phase II Study of FCN-159 in NF2 Nerve Sheath TumorsRecruitingNCT06553365Phase 21 country
- Learning Curve for the Visualization of Sacral Plexus on TVSNot yet recruitingNCT060413471 country
- Neoadjuvant Nivolumab Plus Ipilimumab for Newly Diagnosed Malignant Peripheral Nerve Sheath TumorCompletedNCT04465643Phase 11 country
- Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by SurgeryCompletedNCT02180867Phase 2/33 countries
- Tazemetostat in Malignant Peripheral Nerve Sheath TumorsActive, not recruitingNCT04917042Phase 21 country
- Radiographic Prediction of the Nerve Origin of Neck Peripheral Nerve Sheath TumorsStatus unknownNCT056848351 country
- Pirfenidone in Children and Young Adults With Neurofibromatosis Type I and Progressive Plexiform NeurofibromasCompletedNCT00076102Phase 21 country
- Proton Radiation Therapy for Spinal TumorsWithdrawnNCT01567787Not applicable
- Imatinib Mesylate Treatment of Patients With Malignant Peripheral Nerve Sheath TumorsTerminatedNCT00427583Phase 2/31 country