Drug
Luvometinib clinical trials
Also written FCN-159.
- studies test it
- 13
- open now
- 11
- in phase 3
- 2
- first study started
- 2021
Keep track of what changes. Save the luvometinib studies recruiting or about to start, and get an email each week — studies that open, close, add sites or post results.
Watch these studiesHow studies write it
Studies that test it under each name
Name
Development codes
Combined with it in one product
Studies by the year they started
13 studies that test it; most in 2026 (6)
| Year | Studies |
|---|---|
| 2021 | 1 |
| 2023 | 2 |
| 2024 | 1 |
| 2025 | 3 |
| 2026 | 6 |
By phase
A phase 1/2 study counts in both.
- Phase 1
- 3
- Phase 2
- 9
- Phase 3
- 2
- No phase
- 2
What it is tested for
Each study’s main condition, where its own words name it.
Who runs them
Industry 6 · Other 7
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. (6) · Beijing Tiantan Hospital (2) · West China Second University Hospital (2) · Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (1) · Cancer Institute and Hospital, Chinese Academy of Medical Sciences (1) · Xuanwu Hospital, Beijing (1)
Often tested with
Tested in the same studies.
Studies
Open first, then newest update. How each study uses luvometinib is read from its arms, and is right about nine times in ten.
Testing it · 13
- A Phase 2 Study of Luvometinib Combined With Anlotinib in KRAS-mutated NSCLCRecruitingPhase 2Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.NCT07562581Written as luvometinib + anlotinib
- Response-adapted Luvometinib With or Without Cytarabine in Langerhans Cell HistiocytosisNot yet recruitingPhase 2Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong UniversityNCT07728201Written as Luvometinib
- Platform Research for Innovative Medicines in NF2-SWN (PRIME-NF2)Not yet recruitingPhase 2Beijing Tiantan HospitalNCT07713745Written as Luvometinib
- Luvometinib in Combination With Serplulimab for NF2-Related TumorsNot yet recruitingPhase 1/2Beijing Tiantan HospitalNCT07708285Written as Luvometinib
- Modified LCH-III Regimen With or Without Luvometinib for Multisystem Pediatric Langerhans Cell HistiocytosisRecruitingNot applicableWest China Second University HospitalNCT07431060Written as Luvometinib
- Luvometinib in Pediatric SS-LCH With Special-site Single/Multifocal Bone LesionsRecruitingNot applicableWest China Second University HospitalNCT07371182Written as Luvometinib
- Phase II Study of FCN-159 in NF2 Nerve Sheath TumorsRecruitingPhase 2Cancer Institute and Hospital, Chinese Academy of Medical SciencesNCT06553365Written as FCN-159
- Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1Not yet recruitingPhase 1/2Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.NCT07024394Written as Luvometinib Tablets
- FCN-159 Monotherapy Versus Chemotherapy by Investigator's Choice in Pediatric Low-grade Glioma Patients With BRAF AlterationNot yet recruitingPhase 3Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.NCT07004075Written as Luvometinib
- An Exploratory Study to Evaluate the Efficacy and Safety of FCN-159 in Patients With Brain Arteriovenous MalformationsRecruitingPhase 2Xuanwu Hospital, BeijingNCT06913725Written as FCN-159
- To Evaluate the Efficacy, Safety, and PK Characteristics of FCN-159 in Pediatric Patients With Refractory/Recurrent LCHRecruitingPhase 2Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.NCT05997602Written as FCN-159
- FCN-159 in Adult Patients With Symptomatic, Inoperable Neurofibromatosis Type 1-Related Plexiform NeurofibromasActive, not recruitingPhase 3Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.NCT05913037Written as Test group (Group A): FCN-159 8 mg, orally, once daily;
- Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1Active, not recruitingPhase 1/2Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd.NCT04954001Written as FCN-159
Codes
What other systems call luvometinib · ClinicalTrials.gg INT016057
- UNII (FDA) B2DYT4V89XLUVOMETINIBConfirmed FDA, Wikidata
- Wikidata Q135746264luvometinibConfirmed FDA, Wikidata
- NCI Thesaurus C172382LuvometinibOne source FDA
- DrugBank DB21696One source Wikidata
| System | Code | Name there | Checked by |
|---|---|---|---|
| UNII (FDA) | B2DYT4V89X | LUVOMETINIB | Confirmed FDA, Wikidata |
| Wikidata | Q135746264 | luvometinib | Confirmed FDA, Wikidata |
| NCI Thesaurus | C172382 | Luvometinib | One source FDA |
| DrugBank | DB21696 | — | One source Wikidata |
“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.