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Migraine with Aura clinical trials

The registry lists 114 studies for Migraine with Aura across more than 10 countries. 22 are recruiting or about to start. 53 of them are mainly about Migraine with Aura (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-05.

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Status

Completed
60
Recruiting
17
Status unknown
13
Terminated
9
Active, not recruiting
6
Withdrawn
4

Phase

Phase 2
19
Phase 3
16
Phase 4
10
Phase 1
5
Early Phase 1
2

Where

United States
40
Denmark
20
Italy
9
France
6
Spain
5
Turkey
5

Who runs them

Danish Headache Center (10) · Satsuma Pharmaceuticals, Inc. (5) · University of Florence (5) · Wake Forest University Health Sciences (3) · Glostrup University Hospital, Copenhagen (3) · Minster Research Ltd (3) · Swedish Medical Center (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (3)

What is being tested here

Drugs under test in Migraine with Aura studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Topiramate148
Calcitonin Gene-Related Peptide104
Propranolol112
Melatonin101
Pituitary Adenylate Cyclase-Activating Polypeptide101
EVO756101
Rimegepant101
Zavegepant101
Atogepant101
Amitriptyline101

Drug classes tested here CGRP receptor antagonists 2 open · Serotonin receptor agonists 6 · NSAIDs 4

Coming up

2phase 3 studies under way
11studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest

Who these studies take

Of the 17 Migraine with Aura studies recruiting now, 7 (41%) set no upper age limit and 9 (53%) stop at 75 or younger. 2 (12%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (12%) take healthy volunteers.

Recruiting studies that take each age, of 17
AgeWomenMen
102 (12%)2 (12%)
1816 (94%)16 (94%)
3016 (94%)16 (94%)
4016 (94%)16 (94%)
5016 (94%)16 (94%)
6515 (88%)15 (88%)
759 (53%)9 (53%)
857 (41%)7 (41%)

Across all 114 studies, recruiting or not: 68% stop at 75 or younger and 59% at 65; 15% take children; 4% are for women only and 0% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Migraine with Aura studies take

Of 23 interventional studies with no phase under Migraine with Aura, half reached primary completion within 25 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase25 mo12–34 · 23 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 13, 2026.

Started recruiting1

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 114. Browse all 114 → or search them.