An observational study in Myelomeningocele, Extubation Time and Neonatal, sponsored by Gaziantep City Hospital. Active, not recruiting at 1 site in Turkey (Türkiye). Open to participants aged 0 Days to 28 Days. Per ClinicalTrials.gov, last updated 2026-03-11.
Sponsored by Gaziantep City Hospital · Observational
Meningomyelocele is one of the most common neural tube defects requiring surgical repair in the neonatal period. Postoperative respiratory complications and the need for prolonged mechanical ventilation are important causes of morbidity in these patients. The timing of extubation may influence postoperative respiratory outcomes and the duration of neonatal intensive care unit (NICU) stay. This retrospective cohort study aims to evaluate the impact of operating room extubation on postoperative outcomes in neonates undergoing meningomyelocele repair at Gaziantep City Hospital. Clinical, laboratory, and perioperative data will be obtained from hospital records. Postoperative mechanical ventilation requirement, duration of ventilation, NICU length of stay, and perioperative laboratory changes will be compared between neonates extubated in the operating room and those extubated in the intensive care unit.
56 studies on the registry are indexed under Meningomyelocele; 14 are open to participants now.
This study's planned enrollment of 60 is above the median of 30 across 17 observational studies indexed under Meningomyelocele.
Browse Meningomyelocele studies →Gaziantep City Hospital is the lead sponsor of 21 studies on the registry; 14 are open to participants now.
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Neonates who underwent meningomyelocele repair under general anesthesia at Gaziantep City Hospital between November 2023 and March 2026. All patients were followed postoperatively in the neonatal intensive care unit, and perioperative clinical and laboratory data were obtained from hospital medical records.
Exclusion Criteria:
Neonates who were extubated in the operating room immediately after meningomyelocele repair.
Neonates who were transferred intubated to the NICU and extubated in the intensive care unit after meningomyelocele repair.
Postoperative Mechanical Ventilation Requirement
Requirement for invasive mechanical ventilation after meningomyelocele repair in neonates.
Time frame: Within the first 48 hours after surgery
Length of NICU Stay
Duration of stay in the neonatal intensive care unit following meningomyelocele repair.
Time frame: From surgery until discharge from the neonatal intensive care unit, up to 30 days
Change in Blood pH
Difference between preoperative and postoperative blood pH values.
Time frame: Preoperative vs postoperative 24 hours
Change in Lactate Level
Difference between preoperative and postoperative blood lactate levels.
Time frame: Baseline (preoperative) and 24 hours after surgery
Plan to share: No
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This study is active, not recruiting, as verified in Mar 2026. You cannot join it, but the record below documents what was studied.
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Gaziantep City Hospital