Malaria: all 1,315 studies

Page 3 of 14. Open to participants first (86), then studies with results posted, then the rest; newest registration first within each.

• Phase II Efficacy Study of Artefenomel & Piperaquine in Adults & Children With P. Falciparum Malaria.CompletedNCT02083380Phase 2/3Results posted
• Plasmodium Vivax Efficacy Trial in Cruzeiro do Sul, Acre, BrazilCompletedNCT02043652Not applicableResults posted
• Safety and Immunogenicity of Plant-Derived Pfs25 VLP-FhCMB Malaria Transmission Blocking Vaccine in Healthy AdultsCompletedNCT02013687Phase 1Results posted
• A Safety and Feasibility Study of Enteral LVT vs. Standard of Care for Seizure Control in Pediatric CMCompletedNCT01982812Phase 2Results posted
• Novel Use Of Hydroxyurea in an African Region With MalariaCompletedNCT01976416Phase 3Results posted
• Open Label Pharmacokinetic Study of OZ439 and Piperaquine on Administration of OZ439+TPGS Granules for Oral Suspension Alone or With Either Piperaquine Phosphate Tablets or Granules for Oral Solution in Healthy VolunteersCompletedNCT01958619Phase 1Results posted
• Evaluation of Oral Activated Charcoal on Antimalarial Drug's Ability to Kill Parasites in Malian Children With MalariaCompletedNCT01955382Phase 2Results posted
• Epidemiology Study of Malaria Transmission Intensity in Sub-Saharan AfricaCompletedNCT01954264Not applicableResults posted
• Relative Bioavailability of Pyronaridine-artesunate in Tablet and Granule Formulations in Healthy VolunteersCompletedNCT01868438Phase 1Results posted
• A Study to Assess Efficacy, Safety of KAE609 in Adult Patients With Acute Malaria Mono-infectionCompletedNCT01860989Phase 2Results posted
• Efficacy, Safety and Immunogenicity Study of GlaxoSmithKline(GSK) Biologicals' Candidate Malaria Vaccine 257049 in the Sporozoite Challenge Model in Healthy Malaria-naïve AdultsCompletedNCT01857869Phase 2Results posted
• Healthy Volunteer Study of the Pharmacokinetics of Oral Piperaquine With OZ439 + TPGS Formulation in the Fasted StateCompletedNCT01853475Phase 1Results posted
• A Study to Find the Minimum Inhibitory Concentration of KAE609 in Adult Male Patients With P. Falciparum MonoinfectionCompletedNCT01836458Phase 2Results posted
• Efficacy, Safety, Tolerability and Pharmacokinetics of KAF156 in Adult Patients With Acute, Uncomplicated Plasmodium Falciparum or Vivax Malaria Mono-infectionCompletedNCT01753323Phase 2Results posted
• Preserving ACTs - Text Reminders to Increase Adherence to ACT TreatmentCompletedNCT01722734Not applicableResults posted
• OZ439 PhIIa Study in Plasmodium Falciparum: Extended ObservationCompletedNCT01713621Phase 2Results posted
• A Dose-escalation Study to Investigate Safety and Toleration of OZ439CompletedNCT01713608Phase 1Results posted
• Enteral Levetiracetam For Seizure Control In Pediatric Cerebral MalariaCompletedNCT01660672Phase 1/2Results posted
• Efficacy, Safety and Pharmacokinetics of Artemether-lumefantrine Dispersible Tablet in the Treatment of Malaria in Infants < 5 kgCompletedNCT01619878Phase 2/3Results posted
• Safety, Tolerability & Pharmacokinetics (PK) of Co-administered Single Doses of OZ439 and Mefloquine (MQ) in Healthy VolunteersTerminatedNCT01615822Phase 1Results posted
• Studies of a Candidate Aminoquinoline Antimalarial (AQ-13)CompletedNCT01614964Phase 2Results posted
• Phase II Dose-ranging Study of Pyronaridine/Artesunate in Adults Patients With Plasmodium Falciparum MalariaCompletedNCT01594931Phase 2Results posted
• Trial of a Falciparum Malaria Protein (FMP012), E. Coli-expressed PfCelTOS, in Healthy Malaria-Naive AdultsCompletedNCT01540474Phase 1Results posted
• Drug Interaction Study of Pyronaridine-artesunate & Metoprolol, & Redosing Study of Pyronaridine-artesunateCompletedNCT01523002Phase 1Results posted
• Optimisation of Controlled Human Malaria Infection Using Sporozoites Administered by Needle and SyringeCompletedNCT01465048Not applicableResults posted
• Chloroquine for Malaria in PregnancyCompletedNCT01443130Phase 3Results posted
• Stimulating Private Sector Malaria ControlCompletedNCT01397851Not applicableResults posted
• Human Mass Balance Study of PyronaridineCompletedNCT01383109Phase 1Results posted
• Ph 2B/3 Tafenoquine (TFQ) Study in Prevention of Vivax RelapseCompletedNCT01376167Phase 2Results posted
• Safety, Immunogenicity and Efficacy Against of a Combined Malaria Vaccine in Healthy Malaria-naïve AdultsCompletedNCT01366534Phase 2Results posted
• Study to Evaluate Immunogenicity of the Hepatitis B Antigen of the GSK Biologicals' Candidate Malaria Vaccine (257049)CompletedNCT01345240Phase 3Results posted
• Consistency of Immunogenicity and Non Inferiority of GSK Biologicals' Candidate Malaria Vaccine Lots in ChildrenCompletedNCT01323972Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Tafenoquine for the Treatment of Plasmodium Vivax in AdultsTerminatedNCT01290601Phase 2Results posted
• Superiority of ArTiMist Versus Quinine in Children With Severe MalariaCompletedNCT01258049Phase 3Results posted
• A Community Setting Study of Malaria After Systematic Treatment of Symptomatic Carriers of P. Falciparum With COA566 (Coartem®)CompletedNCT01256658Phase 4Results posted
• Safety and Immunogenicity of GSK Biologicals' Malaria Vaccine 257049 When Administered on 7 Schedules to African InfantsCompletedNCT01231503Phase 2Results posted
• Efficacy, Tolerability, PK of OZ439 in Adults With Acute, Uncomplicated P.Falciparum or Vivax Malaria Mono-infectionCompletedNCT01213966Phase 2Results posted
• Epidemiology Study of Malaria Transmission Intensity in AfricaCompletedNCT01190202Not applicableResults posted
• Study of VMP001 and AS01B (Adjuvant Formulation) in Healthy Malaria-Naïve AdultsCompletedNCT01157897Phase 1/2Results posted
• Pyronaridine Artesunate-Ritonavir Drug-drug Interaction StudyCompletedNCT01156389Phase 1Results posted
• Safety and Immunogenicity of GSK Biologicals' Investigational Malaria Vaccine in HIV Infected Infants and ChildrenCompletedNCT01148459Phase 3Results posted
• Evaluate Azithromycin Plus Chloroquine And Sulfadoxine Plus Pyrimethamine Combinations For Intermittent Preventive Treatment Of Falciparum Malaria Infection In Pregnant Women In AfricaTerminatedNCT01103063Phase 3Results posted
• Efficacy of ArTiMist™ in ChildrenCompletedNCT01047436Phase 2Results posted
• Phase 1/2a Trial of Pf GAP p52-/p36- Sporozoite Malaria VaccineTerminatedNCT01024686Phase 1/2Results posted
• Protease Inhibitors to Reduce Malaria Morbidity in HIV-Infected Pregnant WomenCompletedNCT00993031Phase 3Results posted
• Weekly Dosing of Malarone ® for Prevention of MalariaCompletedNCT00984256Phase 2Results posted
• HIV Protease Inhibitors for the Prevention of Malaria in Ugandan ChildrenCompletedNCT00978068Phase 3Results posted
• Chemopreventive Therapy for Malaria in Ugandan ChildrenCompletedNCT00948896Phase 3Results posted
• A Study to Investigate the Safety, Tolerability and Pharmacokinetics of OZ439 in Healthy Male and Female SubjectsCompletedNCT00928083Phase 1Results posted
• Efficacy of GSK Biologicals' Candidate Malaria Vaccine 257049 Against Malaria Disease in Infants and Children in AfricaCompletedNCT00866619Phase 3Results posted
• Intermittent Preventive Treatment of Malaria in SchoolchildrenCompletedNCT00852371Phase 3Results posted
• Bioequivalence Trial of Pyronaridine Artesunate To-be-marketed Tablet to the Clinical Trial Reference TabletCompletedNCT00682630Phase 1Results posted
• Azithromycin Plus Chloroquine Versus Artemether-Lumefantrine For The Treatment Of Uncomplicated P. Falciparum Malaria In Children In AfricaCompletedNCT00677833Phase 2/3Results posted
• Pyronaridine Artesunate 3:1 Granule Formulation vs. Coartem© Crushed Tablets in P. Falciparum Malaria Pediatric PatientsCompletedNCT00541385Phase 3Results posted
• Zambia Integrated Management of Malaria and Pneumonia StudyCompletedNCT00513500Not applicableResults posted
• Chloroquine and Post Malaria Anaemia StudyCompletedNCT00473837Not applicableResults posted
• Phase II AMA-1 Malaria Vaccine FMP2.1/AS02A Trial in MaliCompletedNCT00460525Phase 2Results posted
• Evaluation of Potential Effect of Artemether - Lumefantrine and Malaria Drugs on Auditory FunctionCompletedNCT00444106Phase 4Results posted
• Pyronaridine Artesunate (3:1) in Children and Adults With Acute Plasmodium Vivax MalariaCompletedNCT00440999Phase 3Results posted
• Safety and Immunogenicity Study of GSK Biologicals' Malaria Vaccine 257049, When Incorporated Into an EPI RegimenCompletedNCT00436007Phase 2Results posted
• Pyronaridine Artesunate (3:1) Versus Coartem® in P Falciparum Malaria PatientsCompletedNCT00422084Phase 3Results posted
• Pyronaridine - Artesunate (3:1) Versus Mefloquine Plus Artesunate in Plasmodium Falciparum Malaria PatientsCompletedNCT00403260Phase 3Results posted
• NMRC-M3V-Ad-PfCA Vaccine - Clinical Trial 1CompletedNCT00392015Phase 1/2Results posted
• Efficacy of RTS,S/AS01 Vaccine Against Episodes of Malaria Due to P. Falciparum Infection in Children.CompletedNCT00380393Phase 2Results posted
• Chloroquine Alone or in Combination for Malaria in Children in MalawiCompletedNCT00379821Phase 3Results posted
• Evaluation of Reproducibility of a Sporozoite Challenge Model for Plasmodium Vivax in Human VolunteersCompletedNCT00367380Phase 2Results posted
• Partially-blind (Observer-blind) Study of Safety and Immunogenicity of Two Malaria Vaccines in Ghanaian ChildrenCompletedNCT00360230Phase 2Results posted
• Phase I Pediatric FMP2.1/AS02A Trial in MaliCompletedNCT00358332Phase 1Results posted
• FMP2.1/AS02A: Rabies Vaccine Malaria-Experienced Adults in Bandiagara, MaliCompletedNCT00349713Phase 1Results posted
• Pyronaridine and Artesunate (3:1) in Children With Acute Uncomplicated Plasmodium Falciparum MalariaCompletedNCT00331136Phase 2Results posted
• Long-Term Follow-up of Children for a 2-Year Period to Confirm the Safety and Immunogenicity of GSK 257049 VaccineCompletedNCT00323622Phase 2Results posted
• Phase 1 Trial of a Malaria Vaccine in Young Kenyan ChildrenCompletedNCT00317473Phase 1Results posted
• Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of AmericaCompletedNCT00312702Phase 1/2Results posted
• Phase I/II Trial of a Malaria Vaccine in Adults Living in the United States of AmericaCompletedNCT00312663Phase 1/2Results posted
• Safety Study of Candidate Malaria Vaccine FMP1/AS02A in Healthy Adults in Bandiagara, MaliCompletedNCT00308061Phase 1Results posted
• Safety and Efficacy Study of IV Artesunate to Treat MalariaCompletedNCT00298610Phase 2Results posted
• Artemisinin-Based Combination Therapy: Clinical Trials in CameroonCompletedNCT00297882Phase 3Results posted
• Study of the Safety of Intravenous ArtesunateCompletedNCT00292942Phase 1Results posted
• Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria Vaccine in Tanzanian InfantsCompletedNCT00289185Phase 2Results posted
• A Three Day Trial of Azithromycin Plus Chloroquine for the Treatment of Uncomplicated Plasmodium Falciparum MalariaCompletedNCT00282919Phase 2Results posted
• Double-blind, Randomized, Controlled Study of Safety, Immunogenicity and Efficacy of a Candidate Malaria VaccineCompletedNCT00223990Phase 2Results posted
• Safety, Immunogenicity of RTS,S/AS02A, and RTS,S/AS01B Malaria Vaccines in Malaria-experienced Adults.CompletedNCT00197054Phase 2Results posted
• Examine Safety and Immune Responses of GSK 257049 Vaccine When Administered to Infants Living in a Malaria-endemic RegionCompletedNCT00197028Phase 2Results posted
• Mortality Control Program for Economically Productive Age Group in Tribal Area of Melghat.CompletedNCT07436104Phase 4
• Health Systems Implementation and Molecular Surveillance of Multiple First-Line Treatments for Uncomplicated Malaria in Western KenyaCompletedNCT07362498
• Impact of Malaria Mass Drug Administration on Malaria Prevalence in Under 15 Children and Pregnant WomenCompletedNCT07358767Not applicable
• Clinical Prediction Models for Pediatric In-Hospital Death Risk in Congolese Severe Malaria Children Using Machine Learning Based-AlgorithmsCompletedNCT07355426
• MDA and Targeted Control Against Plasmodium Carriage in the SahelActive, not recruitingNCT07281443Not applicable
• L9LS-R21 InteractionWithdrawnNCT07208760Phase 2
• Knowledge and Attitude Among Healthcare Workers Towards Malaria Vaccine, Sudan 2025.CompletedNCT07194499
• A Challenge Study to Assess the Blood-stage Efficacy of Full-length SUM-101 Malaria Vaccine CandidateWithdrawnNCT07124156Phase 1
• Comparative Study of Thrombocytopenia in Plasmodium Vivax and Falciparum MalariaCompletedNCT07122232
• Monoclonal Antibodies in Children With Severe Anaemia or Severe Malaria to Prevent Malaria After Hospital DischargeActive, not recruitingNCT07082205Phase 3
• L9LS in Women of Childbearing Potential in MaliCompletedNCT07060508Phase 2
• Clinical Practices for Treating Severe Malaria Caused by P. FalciparumCompletedNCT07027722
• Efficacy of Artemether-Lumefantrine in the Treatment of Uncomplicated Plasmodium Falciparum Malaria in Children Under 12 Years at Four Sentinel Sites in MozambiqueCompletedNCT06970600Not applicable
• Private Medicine Retailer-based Trial of Malaria Tests and Conditional Treatment Subsidies Among Patients With FeverCompletedNCT06928207Phase 4
• IGHID 12334 - After the Flood: Optimal Strategies to Prevent Malaria Epidemics Caused by Severe FloodingActive, not recruitingNCT06870344Not applicable
• A Study of Oral E1018 in Healthy Adult ParticipantsActive, not recruitingNCT06854042Phase 1
• MaCRA Part B in NigeriaWithdrawnNCT06805110Not applicable

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