ClinicalTrials.gg
CompletedNCT01190202Updated Aug 18, 2020Results posted

Epidemiology Study of Malaria Transmission Intensity in Africa

An interventional study of Blood sampling and Assessment of body temperature in Malaria and Malaria Vaccines, sponsored by GlaxoSmithKline. Completed at 8 sites in 6 countries. Open to participants aged 6 Months and older, including healthy volunteers. Per ClinicalTrials.gov, last updated 2020-08-18.

Sponsored by GlaxoSmithKline · Not applicable, Interventional, and Other

Phase
Not applicable
Study type
Interventional
Enrollment
21,618
Allocation
Not applicable
Ages
6 Months and older
Sex
All
01

Study summary

The aim of this epidemiology study is to characterize in a standardized way malaria transmission intensity at the clinical trial centers participating in study 110021 (NCT00866619).

Read the detailed description

This study is a multicenter epidemiology study at centers that are participating in GSK's pivotal Phase III candidate malaria vaccine 110021 ( NCT00866619) trial and will involve 4 annual cross sectional surveys performed preferably at peak transmission.

There will be no study vaccine administered in this epidemiology study.

02

Conditions studied

  • Malaria
  • Malaria Vaccines

Keywords

  • Malaria
  • Plasmodium falciparum
03

In context

Malaria

1,184 studies on the registry are indexed under Malaria; 79 are open to participants now.

This study's enrollment of 21,618 is above the median of 252 across 937 interventional studies indexed under Malaria.

Browse Malaria studies →

Lead sponsor

GlaxoSmithKline is the lead sponsor of 3,650 studies on the registry; 118 are open to participants now.

Of its 264 completed or terminated interventional studies of FDA-regulated products, 241 (91%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
6 Months and older
Sexes eligible
All
Accepts healthy volunteers
Yes

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Subjects who the investigator believes that they and/or their parent(s)/Legally Acceptable Representative(s) can and will comply with the requirements of the protocol.
  • A male or female 6 months or older at the time of survey.
  • Written obtained from the subject/from the parent(s)/ Legally Acceptable Representative(s) of the subject.

Exclusion criteria

Exclusion Criteria:

  • Child in care.
  • Previous or current participation in any malaria vaccine trial.
Terms in these criteria, in plain language(1)

Underlined terms in the criteria open these too. Explained by clinicaltrials.gg, not part of the registry record. The study team decides who can take part.

Informed consent

Before you join, the study team explains what taking part involves — its purpose, what happens, the risks and possible benefits — and answers your questions, so you can decide freely. Consent is usually recorded on a form (the informed consent form, ICF) signed by you or, where the law allows, by someone legally authorised to decide for you.

You can keep asking questions during the study, you are told of new information that matters, and you can choose to leave at any time.

05

Study design

Phase
Not applicable
Primary purpose
Other
Allocation
Not applicable
Intervention model
Single group
Enrollment
21,618 participants (actual)

Study arms

  • Experimental
    Overall Study Group (Survey 1)

    Subjects at least 6 months of age at the time of Survey 1, conducted at Year 1 of the 4 annual cross sectional surveys performed preferably at peak transmission (end of rainy season), infected with P. falciparum parasite. Infection determined using a blood smear slide and determined using microscopy. Subjects were enrolled from the catchment areas of study 110021 (NCT00866619) but those who previously participated in study 110021 were excluded from this epidemiological study.

    Procedure: Blood sampling · Procedure: Assessment of body temperature

  • Experimental
    Overall Study Group (Survey 2)

    Subjects at least 6 months of age at the time of Survey 2, conducted at Year 2 of the 4 annual cross sectional surveys performed preferably at peak transmission (end of rainy season), infected with P. falciparum parasite. Infection determined using a blood smear slide and determined using microscopy. Subjects were enrolled from the catchment areas of study 110021 (NCT00866619) but those who previously participated in study 110021 were excluded from this epidemiological study.

    Procedure: Blood sampling · Procedure: Assessment of body temperature

  • Experimental
    Overall Study Group (Survey 3)

    Subjects at least 6 months of age at the time of Survey 3, conducted at Year 3 of the 4 annual cross sectional surveys performed preferably at peak transmission (end of rainy season), infected with P. falciparum parasite. Infection determined using a blood smear slide and determined using microscopy. Subjects were enrolled from the catchment areas of study 110021 (NCT00866619) but those who previously participated in study 110021 were excluded from this epidemiological study.

    Procedure: Blood sampling · Procedure: Assessment of body temperature

  • Experimental
    Overall Study Group (Survey 4)

    Subjects at least 6 months of age at the time of Survey 4, conducted at Year 4 of the 4 annual cross sectional surveys performed preferably at peak transmission (end of rainy season), infected with P. falciparum parasite. Infection determined using a blood smear slide and determined using microscopy. Subjects were enrolled from the catchment areas of study 110021 (NCT00866619) but those who previously participated in study 110021 were excluded from this epidemiological study.

    Procedure: Blood sampling · Procedure: Assessment of body temperature

Interventions

  • ProcedureBlood sampling

    Capillary blood samples collected by finger/heel prick

  • ProcedureAssessment of body temperature

    Assessment of axial body temperature with a digital thermometer

06

What researchers measure

Primary outcomes

  1. Number of Subjects With Plasmodium Falciparum (P. Falciparum) Parasitaemia (PFP), for Each Survey

    The Overall parasite prevalence (PP) data were collected across centers from subjects aged between and including: 6 months to 4 Years (6M-4Y), 5 to 19 Years (5-19 Y) and 20 Years or older (20Y+), for each Survey. The number of subjects P. Falciparum parasitemia infected among the number of subjects with known result for P.falciparum parasitemia test was tabulated.

    Time frame: At each Survey visit

Secondary outcomes

  1. Number of Subjects With Plasmodium Falciparum (P. Falciparum) Parasitaemia (PFP), According to Annual Age for Children of 4 Years or Less, for Each Survey

    The overall parasite prevalence (PP) data were collected across centers from subjects aged 4 years or less, for each Survey. The number of subjects P. Falciparum parasitemia infected among the number of subjects with known result for P.falciparum parasitemia test was tabulated.

    Time frame: At each Survey visit

  2. Number of Subjects With Anemia and Severe Anemia for Each Survey

    The overall anemia and severe anemia data were collected across centers from subjects, aged between and including: 6M-4Y, 5-19 Y and 20Y+, for each survey. Hemoglobin (Hgb) cut-offs used to define anemia and severe anemia in people living at sea level are: Anemia: children 6M to 5Y, Hgb lower than (\<) 11 gram per deciliter (g/dL); children 5-11Y, Hgb \<11.5 g/dL; children 12-13Y, Hgb \<12 g/dL; non-pregnant females, Hgb \<12 g/dL; pregnant females, Hgb \<11 g/dL; males, Hgb \<13 g/dL. Severe anemia: any age or gender, Hgb \<7 g/dL. Missing/ Not applicable (NA) = if age or pregnancy status was not available. Among each age category, results for both sub-categories "Yes" (subjects with anemia) and "Missing/NA" are presented below, results for the category "No" can be deduced from the number of participants analyzed in the corresponding age category, minus (number of "Yes" + number of "Missing/NA"). Similar presentation is followed for "severe anemia" results.

    Time frame: During the survey period (approximatively 1 year)

  3. Number of Subjects With Anti-malarial Therapy in Survey 1, According to Parasite Density

    The overall anti-malaria therapy data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg). Results include the following categories: Malaria treatment (MT) in past 14 days with sub-categories assessed: Yes, No; Exact days of malaria treatment (EDMT) with sub-categories assessed: Ongoing, 1-3 Days, ≥ 4 Days, Missing/NA; Other medication (OM) in past 14 days with sub-categories assessed: Yes, No; Days of other medication (DOM) with sub-categories assessed: Ongoing, 1-7 Days, ≥ 8 Days, Missing/NA; Malaria hospitalization (MH) in the last 3 months with sub-categories assessed: Yes, No. Missing/NA = Missing or Not Applicable.\* In case of several medication (malaria treatment or other medication) taken per subject, the maximum duration was computed for this study.

    Time frame: During the survey period (approximatively 1 year)

  4. Number of Subjects With Anti-malarial Therapy in Survey 2, According to Parasite Density

    The overall anti-malaria therapy data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg). Results include the following categories: Malaria treatment (MT) in past 14 days with sub-categories assessed: Yes, No; Exact days of malaria treatment (EDMT) with sub-categories assessed: Ongoing, 1-3 Days, ≥ 4 Days, Missing/NA; Other medication (OM) in past 14 days with sub-categories assessed: Yes, No; Days of other medication (DOM) with sub-categories assessed: Ongoing, 1-7 Days, ≥ 8 Days, Missing/NA; Malaria hospitalization (MH) in the last 3 months with sub-categories assessed: Yes, No. Missing/NA = Missing or Not Applicable.\* In case of several medication (malaria treatment or other medication) taken per subject, the maximum duration was computed for this study.

    Time frame: During the survey period (approximatively 1 year)

  5. Number of Subjects With Anti-malarial Therapy in Survey 3, According to Parasite Density

    The overall anti-malaria therapy data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg). Results include the following categories: Malaria treatment (MT) in past 14 days with sub-categories assessed: Yes, No; Exact days of malaria treatment (EDMT) with sub-categories assessed: Ongoing, 1-3 Days, ≥ 4 Days, Missing/NA; Other medication (OM) in past 14 days with sub-categories assessed: Yes, No; Days of other medication (DOM) with sub-categories assessed: Ongoing, 1-7 Days, ≥ 8 Days, Missing/NA; Malaria hospitalization (MH) in the last 3 months with sub-categories assessed: Yes, No. Missing/NA = Missing or Not Applicable.\* In case of several medication (malaria treatment or other medication) taken per subject, the maximum duration was computed for this study.

    Time frame: During the survey period (approximatively 1 year)

  6. Number of Subjects With Anti-malarial Therapy in Survey 4, According to Parasite Density

    The overall anti-malaria therapy data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg). Results include the following categories: Malaria treatment (MT) in past 14 days with sub-categories assessed: Yes, No; Exact days of malaria treatment (EDMT) with sub-categories assessed: Ongoing, 1-3 Days, ≥ 4 Days, Missing/NA; Other medication (OM) in past 14 days with sub-categories assessed: Yes, No; Days of other medication (DOM) with sub-categories assessed: Ongoing, 1-7 Days, ≥ 8 Days, Missing/NA; Malaria hospitalization (MH) in the last 3 months with sub-categories assessed: Yes, No. Missing/NA = Missing or Not Applicable.\* In case of several medication (malaria treatment or other medication) taken per subject, the maximum duration was computed for this study.

    Time frame: During the survey period (approximatively 1 year)

  7. Mean Number of Days With Malaria Treatment at Survey 1

    The mean and standard deviation of the number of days of malaria treatment (DMT) were calculated for the past 14 days period of treatment. The malaria treatment data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: During the 14 day-period before the malaria treatment

  8. Mean Number of Days With Malaria Treatment at Survey 2

    The mean and standard deviation of the number of days of malaria treatment (DMT) were calculated for the past 14 days period of treatment. The malaria treatment data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: During the 14 day-period before the malaria treatment

  9. Mean Number of Days With Malaria Treatment at Survey 3

    The mean and standard deviation of the number of days of malaria treatment (DMT) were calculated for the past 14 days period of treatment. The malaria treatment data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: During the 14 day-period before the malaria treatment

  10. Mean Number of Days With Malaria Treatment at Survey 4

    The mean and standard deviation of the number of days of malaria treatment (DMT) were calculated for the past 14 days period of treatment. The malaria treatment data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: During the 14 day-period before the malaria treatment

  11. Number of Subjects With Fever in the Last 24 Hours or at Visit During Survey 1

    Measured characteristics of fever were the following: Fever in the last 24 hours (F 24h) and Fever at visit (F at V). Note: Fever set to "Yes" if temperature recorded after axillary conversion was ≥ 37.5 degrees Celsius (°C). Missing/NA = Missing or Not Applicable. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: In the last 24 hours or at the survey visit

  12. Number of Subjects With Fever in the Last 24 Hours or at Visit During Survey 2

    Measured characteristics of fever were the following: Fever in the last 24 hours (F 24h) and Fever at visit (F at V). Note: Fever set to "Yes" if temperature recorded after axillary conversion was ≥ 37.5 degrees Celsius (°C). Missing/NA = Missing or Not Applicable. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: In the last 24 hours or at the survey visit

  13. Number of Subjects With Fever in the Last 24 Hours or at Visit During Survey 3

    Measured characteristics of fever were the following: Fever in the last 24 hours (F 24h) and Fever at visit (F at V). Note: Fever set to "Yes" if temperature recorded after axillary conversion was ≥ 37.5 degrees Celsius (°C). Missing/NA = Missing or Not Applicable. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: In the last 24 hours or at the survey visit

  14. Number of Subjects With Fever in the Last 24 Hours or at Visit During Survey 4

    Measured characteristics of fever were the following: Fever in the last 24 hours (F 24h) and Fever at visit (F at V). Note: Fever set to "Yes" if temperature recorded after axillary conversion was ≥ 37.5 degrees Celsius (°C). Missing/NA = Missing or Not Applicable. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: In the last 24 hours or at the survey visit

  15. Mean Number of Days With Fever at Survey 1

    The mean and standard deviation of the number of days ago with fever start (DaFs) were calculated for subjects having fever in the last 24 hours. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: During the survey period (approximatively 1 year)

  16. Mean Number of Days With Fever at Survey 2

    The mean and standard deviation of the number of days ago with fever start (DaFs) were calculated for subjects having fever in the last 24 hours. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: During the survey period (approximatively 1 year)

  17. Mean Number of Days With Fever at Survey 3

    The mean and standard deviation of the number of days ago with fever start (DaFs) were calculated for subjects having fever in the last 24 hours. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: During the survey period (approximatively 1 year)

  18. Mean Number of Days With Fever at Survey 4

    The mean and standard deviation of the number of days ago with fever start (DaFs) were calculated for subjects having fever in the last 24 hours. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: During the survey period (approximatively 1 year)

  19. Axillary Temperature at Visit in Survey 1

    The mean and standard deviation of the axillary temperature at visit (A temp. at V) were calculated. Axillary temperature data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  20. Axillary Temperature at Visit in Survey 2

    The mean and standard deviation of axillary temperature at visit (A temp. at V) were calculated. Axillary temperature data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  21. Axillary Temperature at Visit in Survey 3

    The mean and standard deviation of axillary temperature at visit (A temp. at V) were calculated. Axillary temperature data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  22. Axillary Temperature at Visit in Survey 4

    The mean and standard deviation of axillary temperature at visit (A temp. at V) were calculated. Axillary temperature data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  23. Number of Subjects Living in the Same House at Survey 1

    The malaria prevention and risk factors characteristics were: Number of persons living in the same part of the house (PLSPH) among persons enrolled in the study (PES), in the following combinations: \< y/x (less than \[\<\] y PLSPH among x PES), y-z/x (y to z PLSPH among x PES), \> z/x (more than \[\>\] z PLSPH among x PES), y-z/\> x (y to z PLSPH among more than \[\>\] x PES), \> z/\> x (more than \[\>\] z PLSPH among more than \[\>\] x PES, or missing information). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  24. Number of Subjects Living in the Same House at Survey 2

    The malaria prevention and risk factors characteristics were: Number of persons living in the same part of the house (PLSPH) among persons enrolled in the study (PES), in the following combinations: \< y/x (less than \[\<\] y PLSPH among x PES), y-z/x (y to z PLSPH among x PES), \> z/x (more than \[\>\] z PLSPH among x PES), y-z/\> x (y to z PLSPH among more than \[\>\] x PES), \> z/\> x (more than \[\>\] z PLSPH among more than \[\>\] x PES, or missing information). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  25. Number of Subjects Living in the Same House at Survey 3

    The malaria prevention and risk factors characteristics were: Number of persons living in the same part of the house (PLSPH) among persons enrolled in the study (PES), in the following combinations: \< y/x (less than \[\<\] y PLSPH among x PES), y-z/x (y to z PLSPH among x PES), \> z/x (more than \[\>\] z PLSPH among x PES), y-z/\> x (y to z PLSPH among more than \[\>\] x PES), \> z/\> x (more than \[\>\] z PLSPH among more than \[\>\] x PES, or missing information). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  26. Number of Subjects Living in the Same House at Survey 4

    The malaria prevention and risk factors characteristics were: Number of persons living in the same part of the house (PLSPH) among persons enrolled in the study (PES), in the following combinations: \< y/x (less than \[\<\] y PLSPH among x PES), y-z/x (y to z PLSPH among x PES), \> z/x (more than \[\>\] z PLSPH among x PES), y-z/\> x (y to z PLSPH among more than \[\>\] x PES), \> z/\> x (more than \[\>\] z PLSPH among more than \[\>\] x PES, or missing information). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  27. Mean Number of Subjects Living in the Same House at Survey 1

    The malaria prevention and risk factors characteristics were the following: the mean and standard deviation of the number of persons living in the same part of the house (PLSPH). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  28. Mean Number of Subjects Living in the Same House at Survey 2

    The malaria prevention and risk factors characteristics were the following: the mean and standard deviation of the number of persons living in the same part of the house (PLSPH). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  29. Mean Number of Subjects Living in the Same House at Survey 3

    The malaria prevention and risk factors characteristics were the following: the mean and standard deviation of the number of persons living in the same part of the house (PLSPH). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  30. Mean Number of Subjects Living in the Same House at Survey 4

    The malaria prevention and risk factors characteristics were the following: the mean and standard deviation of the number of persons living in the same part of the house (PLSPH). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  31. Number of Subjects by Localisation and Type of Location at Survey 1

    The malaria prevention and risk factors characteristics were the following: localisation categories (i.e.: rural, urban, semi-rural or missing) and Type of Location (i.e.: Large city: \>1 million habitants; Small city: \>50000 \& \< 1 million habitants; Town: \> 10000 and \< 50000 habitants; Countryside: \< 10000 habitants or missing type of location). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  32. Number of Subjects by Localisation and Type of Location at Survey 2

    The malaria prevention and risk factors characteristics were the following: localisation categories (i.e.: rural, urban, semi-rural) and Type of Location (i.e.: Large city: \>1 million habitants; Small city: \>50000 \& \< 1 million habitants; Town: \> 10000 and \< 50000 habitants; Countryside: \< 10000 habitants). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  33. Number of Subjects by Localisation and Type of Location at Survey 3

    The malaria prevention and risk factors characteristics were the following: localisation categories (i.e.: rural, urban, semi-rural) and Type of Location (i.e.: Large city: \>1 million habitants; Small city: \>50000 \& \< 1 million habitants; Town: \> 10000 and \< 50000 habitants; Countryside: \< 10000 habitants). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  34. Number of Subjects by Localisation and Type of Location at Survey 4

    The malaria prevention and risk factors characteristics were the following: localisation categories (i.e.: rural, urban, semi-rural) and Type of Location (i.e.: Large city: \>1 million habitants; Small city: \>50000 \& \< 1 million habitants; Town: \> 10000 and \< 50000 habitants; Countryside: \< 10000 habitants). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  35. Number of Subjects by House Construction Material Regarding Walls and Floor at Survey 1

    The malaria prevention and risk factors characteristics were the following: Main house construction material (MHCM) walls and MHCM floor. MHCM walls data were assessed for the following sub-categories: mud, brick, cement/plaster, cement/paint, other and missing. MHCM floor data were assessed for the following sub-categories: natural floor, rudimentary floor, parquet polished wood, vinyl or asphalt strips, ceramic tiles, cement, carpet, missing. Note: Natural floor = earth, sand, dung; Rudimentary floor = wood planks, palm, bamboo. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  36. Number of Subjects by House Construction Material Regarding Walls and Floor at Survey 2

    The malaria prevention and risk factors characteristics were the following: Main house construction material (MHCM) walls and MHCM floor. MHCM walls data were assessed for the following sub-categories: mud, brick, cement/plaster, cement/paint, other. MHCM floor data were assessed for the following sub-categories: natural floor, rudimentary floor, parquet polished wood, vinyl or asphalt strips, ceramic tiles, cement, carpet. Note: Natural floor = earth, sand, dung; Rudimentary floor = wood planks, palm, bamboo. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  37. Number of Subjects by House Construction Material Regarding Walls and Floor at Survey 3

    The malaria prevention and risk factors characteristics were the following: Main house construction material (MHCM) walls and MHCM floor. MHCM walls data were assessed for the following sub-categories: mud, brick, cement/plaster, cement/paint, other. MHCM floor data were assessed for the following sub-categories: natural floor, rudimentary floor, ceramic tiles, cement, carpet. Note: Natural floor = earth, sand, dung; Rudimentary floor = wood planks, palm, bamboo. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  38. Number of Subjects by House Construction Material Regarding Walls and Floor at Survey 4

    The malaria prevention and risk factors characteristics were the following: Main house construction material (MHCM) walls and MHCM floor. MHCM walls data were assessed for the following sub-categories: mud, brick, cement/plaster, cement/paint, other. MHCM floor data were assessed for the following sub-categories: natural floor, rudimentary floor, vinyl or asphalt strips, ceramic tiles, cement, carpet. Note: Natural floor = earth, sand, dung; Rudimentary floor = wood planks, palm, bamboo. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  39. Number of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 1

    The malaria prevention and risk factors characteristics were the following: main house construction material (MHCM) roof, windows/eaves, nets. MHCM roof data were assessed for the following sub-categories: grass/palm, iron sheet, tiles, other, missing. MHCM windows/eaves data were assessed for the following sub-categories: closed, open, partially open, missing. MHCM nets data were assessed for the following sub-categories: nets not present, nets present on all windows, nets present on some windows, missing. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  40. Number of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 2

    The malaria prevention and risk factors characteristics were the following: main house construction material (MHCM) roof, windows/eaves, nets. MHCM roof data were assessed for the following sub-categories: grass/palm, iron sheet, tiles, other. MHCM windows/eaves data were assessed for the following sub-categories: closed, open, partially open. MHCM nets data were assessed for the following sub-categories: nets not present, nets present on all windows, nets present on some windows. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  41. Number of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 3

    The malaria prevention and risk factors characteristics were the following: main house construction material (MHCM) roof, windows/eaves, nets. MHCM roof data were assessed for the following sub-categories: grass/palm, iron sheet, tiles, other. MHCM windows/eaves data were assessed for the following sub-categories: closed, open, partially open. MHCM nets data were assessed for the following sub-categories: nets not present, nets present on all windows, nets present on some windows. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  42. Number of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 4

    The malaria prevention and risk factors characteristics were the following: main house construction material (MHCM) roof, windows/eaves, nets. MHCM roof data were assessed for the following sub-categories: grass/palm, iron sheet, other. MHCM windows/eaves data were assessed for the following sub-categories: closed, open, partially open. MHCM nets data were assessed for the following sub-categories: nets not present, nets present on all windows, nets present on some windows. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  43. Number of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 1

    The malaria prevention and risk factors characteristics were the following: Main source of drinking water (MSDW): bottled water, closed water source (piped water, tube well, dug well, protected well), open water source (unprotected well, spring water, rainwater, tanker truck, surface water), missing; and Presence of electricity (PE): Yes, No, missing. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  44. Number of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 2

    The malaria prevention and risk factors characteristics were the following: Main source of drinking water (MSDW): bottled water, closed water source (piped water, tube well, dug well, protected well), open water source (unprotected well, spring water, rainwater, tanker truck, surface water); and Presence of electricity (PE): Yes, No. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  45. Number of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 3

    The malaria prevention and risk factors characteristics were the following: Main source of drinking water (MSDW): bottled water, closed water source (piped water, tube well, dug well, protected well), open water source (unprotected well, spring water, rainwater, tanker truck, surface water); and Presence of electricity (PE): Yes, No. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  46. Number of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 4

    The malaria prevention and risk factors characteristics were the following: Main source of drinking water (MSDW): bottled water, closed water source (piped water, tube well, dug well, protected well), open water source (unprotected well, spring water, rainwater, tanker truck, surface water); and Presence of electricity (PE): Yes, No. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

    Time frame: At Survey visit

  47. Number of Subjects With Malaria Prevention Measures (MPM) at Each Survey

    The malaria prevention measures (MPM) data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for each Survey. The MPM results include the following categories: Use of Mosquito coils over 7 days (UMc \> 7D), Use of Insecticide spray over 7 days (UIs \> 7D), Use of Commercial Repellents over 7 days (UCR \> 7D), Use of Traditional Repellents over 7 days (UTR \> 7D), Use of none of above over 7 days (Una \>7D), Use of indoor residual spray in past 12 months to spray interior walls (Uirs past 12M), Use of indoor residual spray - number of months ago (Uirs-nM) or Use of indoor residual spray- no spray (Uirs-no spray): the number of months ago for each Uirs-nM sub-categories is defined using the following \[x Months\]. Not all Uirs-nM sub-categories were analyzed in each survey.

    Time frame: At each Survey visit

  48. Number of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 1

    Data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. The other Plasmodium species assessed were: P. Malaria, P. Vivax, P. Ovale. Infection were determined using a blood smear slide, and categorized according positive (Pos) and negative (Neg) results.

    Time frame: At Survey visit

  49. Number of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 2

    Data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. The other Plasmodium species assessed were: P. Malaria, P. Vivax, P. Ovale. Infection were determined using a blood smear slide, and categorized according positive (Pos) and negative (Neg) results.

    Time frame: At Survey visit

  50. Number of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 3

    Data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. The other Plasmodium species assessed were: P. Malaria, P. Vivax, P. Ovale. Infection were determined using a blood smear slide, and categorized according positive (Pos) and negative (Neg) results.

    Time frame: At Survey visit

  51. Number of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 4

    Data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. The other Plasmodium species assessed were: P. Malaria, P. Vivax, P. Ovale. Infection were determined using a blood smear slide, and categorized according positive (Pos) and negative (Neg) results.

    Time frame: At Survey visit

  52. Number of Subjects With Serious Adverse Events (SAEs) Related to Study Procedure for Each Survey

    Serious adverse events (SAEs) assessed include medical occurrences that result in death, are life threatening, require hospitalization or prolongation of hospitalization or result in disability/incapacity. Capillary blood sampling was the only invasive procedure involved in this study. SAEs related to this procedure were recorded at the Survey visit.

    Time frame: At each Survey visit

07

Results

Posted Aug 18, 2020

Participant flow

For each year and each site, approximately 400 subjects at least 6 months and \< 5 years old, approximately 200 subjects at least 5 years and \< 20 years old and approximately 200 subjects at least 20 years old were to be enrolled. The study was conducted at 8 sites and 6 countries for the first 3 surveys and 3 sites from 3 countries for Survey 4.

Participant flow — Overall Study
MilestoneOverall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)
Started6404641464002400
Completed6404641464002400
Not completed0000

Outcome measures

PrimaryNumber of Subjects With Plasmodium Falciparum (P. Falciparum) Parasitaemia (PFP), for Each Survey

The Overall parasite prevalence (PP) data were collected across centers from subjects aged between and including: 6 months to 4 Years (6M-4Y), 5 to 19 Years (5-19 Y) and 20 Years or older (20Y+), for each Survey. The number of subjects P. Falciparum parasitemia infected among the number of subjects with known result for P.falciparum parasitemia test was tabulated.

Time frame:
At each Survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Plasmodium Falciparum (P. Falciparum) Parasitaemia (PFP), for Each Survey
ParticipantsOverall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)
6M-4Y, Overall720574605345
5-19Y, Overall446469483278
20+Y, Overall14714619392
SecondaryNumber of Subjects With Plasmodium Falciparum (P. Falciparum) Parasitaemia (PFP), According to Annual Age for Children of 4 Years or Less, for Each Survey

The overall parasite prevalence (PP) data were collected across centers from subjects aged 4 years or less, for each Survey. The number of subjects P. Falciparum parasitemia infected among the number of subjects with known result for P.falciparum parasitemia test was tabulated.

Time frame:
At each Survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Plasmodium Falciparum (P. Falciparum) Parasitaemia (PFP), According to Annual Age for Children of 4 Years or Less, for Each Survey
ParticipantsOverall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)
Children aged 0 year21384125
Children aged 1 year947512862
Children aged 2 years13912212586
Children aged 3 years22317413586
Children aged 4 years24316517686
SecondaryNumber of Subjects With Anemia and Severe Anemia for Each Survey

The overall anemia and severe anemia data were collected across centers from subjects, aged between and including: 6M-4Y, 5-19 Y and 20Y+, for each survey. Hemoglobin (Hgb) cut-offs used to define anemia and severe anemia in people living at sea level are: Anemia: children 6M to 5Y, Hgb lower than (\<) 11 gram per deciliter (g/dL); children 5-11Y, Hgb \<11.5 g/dL; children 12-13Y, Hgb \<12 g/dL; non-pregnant females, Hgb \<12 g/dL; pregnant females, Hgb \<11 g/dL; males, Hgb \<13 g/dL. Severe anemia: any age or gender, Hgb \<7 g/dL. Missing/ Not applicable (NA) = if age or pregnancy status was not available. Among each age category, results for both sub-categories "Yes" (subjects with anemia) and "Missing/NA" are presented below, results for the category "No" can be deduced from the number of participants analyzed in the corresponding age category, minus (number of "Yes" + number of "Missing/NA"). Similar presentation is followed for "severe anemia" results.

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Count of participants · Participants
Number of Subjects With Anemia and Severe Anemia for Each Survey
ParticipantsOverall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)
Overall Yes, Anaemia, 6M-4Y197420251974871
Missing/NA Anemia, 6M-4Y42——
Overall Yes, Anemia, 5-19Y806794765371
Missing/NA Anemia, 5-19Y22——
Overall Yes, Anemia, 20Y+673631651313
Missing/NA Anemia, 20Y+10——
Overall Yes, Severe anaemia, 6M-4Y85708434
Missing/NA Severe anemia, 6M-4Y122611721219322
Overall Yes, Severe anaemia, 5-19Y1012195
Missing/NA Severe anemia, 5-19Y807833847235
Overall Yes, Severe anaemia, 20Y+171494
Missing/NA Severe anemia, 20Y+915956944287
SecondaryNumber of Subjects With Anti-malarial Therapy in Survey 1, According to Parasite Density

The overall anti-malaria therapy data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg). Results include the following categories: Malaria treatment (MT) in past 14 days with sub-categories assessed: Yes, No; Exact days of malaria treatment (EDMT) with sub-categories assessed: Ongoing, 1-3 Days, ≥ 4 Days, Missing/NA; Other medication (OM) in past 14 days with sub-categories assessed: Yes, No; Days of other medication (DOM) with sub-categories assessed: Ongoing, 1-7 Days, ≥ 8 Days, Missing/NA; Malaria hospitalization (MH) in the last 3 months with sub-categories assessed: Yes, No. Missing/NA = Missing or Not Applicable.\* In case of several medication (malaria treatment or other medication) taken per subject, the maximum duration was computed for this study.

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Count of participants · Participants
Number of Subjects With Anti-malarial Therapy in Survey 1, According to Parasite Density
ParticipantsLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, MT in past 14 days, Yes229212262
6M-4Y, MT in past 14 days, No351161561072218
6M-4Y, EDMT *, Ongoing320028
6M-4Y, EDMT *, 1-3 days18529206
6M-4Y, EDMT *, ≥ 4days120327
6M-4Y, EDMT *, Missing/Not applicable351161561072219
6M-4Y, OM in past 14 days, Yes35332133445
6M-4Y, OM in past 14 days, No33813737862035
6M-4Y, DOM *, Ongoing872579
6M-4Y, DOM *, 1-7 days25261927365
6M-4Y, DOM *, ≥ 8 days00001
6M-4Y, DOM *, Missing/Not applicable34013737872035
6M-4Y, MH in the last 3 months, Yes741790
6M-4Y, MH in the last 3 months, No366166571122390
5-19Y, MT in past 14 days, Yes564285
5-19Y, MT in past 14 days, No2896519561082
5-19Y, EDMT *, Ongoing10005
5-19Y, EDMT *, 1-3 days464175
5-19Y, EDMT *, ≥ 4days00015
5-19Y, EDMT *, Missing/Not applicable2896519561082
5-19Y, OM in past 14 days, Yes291287143
5-19Y, OM in past 14 days, No2655915511024
5-19Y, DOM *, Ongoing411217
5-19Y, DOM *, 1-7 days251175125
5-19Y, DOM *, ≥ 8 days00000
5-19Y, DOM *, Missing/Not applicable2655915511025
5-19Y, MH in the last 3 months, Yes030124
5-19Y, MH in the last 3 months, No2946823571143
20Y+, MT in past 14 days, Yes10—0102
20Y+, MT in past 14 days, No11817—111339
20Y+, EDMT *, Ongoing00—014
20Y+, EDMT *, 1-3 days10—080
20Y+, EDMT *, ≥ 4days00—08
20Y+, EDMT *, Missing/Not applicable11817—111339
20Y+, OM in past 14 days, Yes206—2203
20Y+, OM in past 14 days, No9911—91238
20Y+, DOM *, Ongoing51—141
20Y+, DOM *, 1-7 days155—1158
20Y+, DOM *, ≥ 8 days00—02
20Y+, DOM *, Missing/Not applicable9911—91240
20Y+, MH in the last 3 months, Yes02—018
20Y+, MH in the last 3 months, No11915—111423
SecondaryNumber of Subjects With Anti-malarial Therapy in Survey 2, According to Parasite Density

The overall anti-malaria therapy data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg). Results include the following categories: Malaria treatment (MT) in past 14 days with sub-categories assessed: Yes, No; Exact days of malaria treatment (EDMT) with sub-categories assessed: Ongoing, 1-3 Days, ≥ 4 Days, Missing/NA; Other medication (OM) in past 14 days with sub-categories assessed: Yes, No; Days of other medication (DOM) with sub-categories assessed: Ongoing, 1-7 Days, ≥ 8 Days, Missing/NA; Malaria hospitalization (MH) in the last 3 months with sub-categories assessed: Yes, No. Missing/NA = Missing or Not Applicable.\* In case of several medication (malaria treatment or other medication) taken per subject, the maximum duration was computed for this study.

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Count of participants · Participants
Number of Subjects With Anti-malarial Therapy in Survey 2, According to Parasite Density
ParticipantsLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, MT in past 14 days, Yes14625257
6M-4Y, MT in past 14 days, No26914265712366
6M-4Y, EDMT *, Ongoing130125
6M-4Y, EDMT *, 1-3 days12114206
6M-4Y, EDMT *, ≥ 4days121026
6M-4Y, EDMT *, Missing/NA26914265712366
6M-4Y, OM in past 14 days, Yes4215917535
6M-4Y, OM in past 14 days, No24113358592088
6M-4Y, DOM *, Ongoing12632118
6M-4Y, DOM *, 1-7 days309615410
6M-4Y, DOM *, ≥ 8 days00007
6M-4Y, DOM *, Missing/NA24113358592088
6M-4Y, MH in the last 3 months, Yes332377
6M-4Y, MH in the last 3 months, No28014565732546
5-19Y, MT in past 14 days, Yes1132477
5-19Y, MT in past 14 days, No3226827321081
5-19Y, EDMT *, Ongoing110011
5-19Y, EDMT *, 1-3 days812466
5-19Y, EDMT *, ≥ 4days21000
5-19Y, EDMT *, Missing/NA3226827321081
5-19Y, OM in past 14 days, Yes331089134
5-19Y, OM in past 14 days, No3006121271024
5-19Y, DOM *, Ongoing710130
5-19Y, DOM *, 1-7 days26988102
5-19Y, DOM *, ≥ 8 days00002
5-19Y, DOM *, Missing/NA3006121271024
5-19Y, MH in the last 3 months, Yes511119
5-19Y, MH in the last 3 months, No3287028351139
20Y+, MT in past 14 days, Yes200284
20Y+, MT in past 14 days, No12210551357
20Y+, EDMT *, Ongoing00015
20Y+, EDMT *, 1-3 days200172
20Y+, EDMT *, ≥ 4days00007
20Y+, EDMT *, Missing/NA12210551357
20Y+, OM in past 14 days, Yes10223214
20Y+, OM in past 14 days, No1148341227
20Y+, DOM *, Ongoing101271
20Y+, DOM *, 1-7 days9211138
20Y+, DOM *, ≥ 8 days00005
20Y+, DOM *, Missing/NA1148341227
20Y+, MH in the last 3 months, Yes110019
20Y+, MH in the last 3 months, No1239571422
SecondaryNumber of Subjects With Anti-malarial Therapy in Survey 3, According to Parasite Density

The overall anti-malaria therapy data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg). Results include the following categories: Malaria treatment (MT) in past 14 days with sub-categories assessed: Yes, No; Exact days of malaria treatment (EDMT) with sub-categories assessed: Ongoing, 1-3 Days, ≥ 4 Days, Missing/NA; Other medication (OM) in past 14 days with sub-categories assessed: Yes, No; Days of other medication (DOM) with sub-categories assessed: Ongoing, 1-7 Days, ≥ 8 Days, Missing/NA; Malaria hospitalization (MH) in the last 3 months with sub-categories assessed: Yes, No. Missing/NA = Missing or Not Applicable.\* In case of several medication (malaria treatment or other medication) taken per subject, the maximum duration was computed for this study.

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Count of participants · Participants
Number of Subjects With Anti-malarial Therapy in Survey 3, According to Parasite Density
ParticipantsLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, MT in past 14 days, Yes171339267
6M-4Y, MT in past 14 days, No26214871822321
6M-4Y, EDMT *, Ongoing410433
6M-4Y, EDMT *, 1-3 days111035210
6M-4Y, EDMT *, ≥ 4days220024
6M-4Y, EDMT *, Missing/NA26214871822321
6M-4Y, OM in past 14 days, Yes65301818547
6M-4Y, OM in past 14 days, No21413156732041
6M-4Y, DOM *, Ongoing10836142
6M-4Y, DOM *, 1-7 days55221512394
6M-4Y, DOM *, ≥ 8 days000011
6M-4Y, DOM *, Missing/NA21413156732041
6M-4Y, MH in the last 3 months, Yes1443099
6M-4Y, MH in the last 3 months, No26515771912489
5-19Y, MT in past 14 days, Yes1441158
5-19Y, MT in past 14 days, No3279012341071
5-19Y, EDMT *, Ongoing41004
5-19Y, EDMT *, 1-3 days831150
5-19Y, EDMT *, ≥ 4days20004
5-19Y, EDMT *, Missing/NA3279012341071
5-19Y, OM in past 14 days, Yes4418313128
5-19Y, OM in past 14 days, No2977610221001
5-19Y, DOM *, Ongoing1310219
5-19Y, DOM *, 1-7 days3117311109
5-19Y, DOM *, ≥ 8 days00000
5-19Y, DOM *, Missing/NA2977610221001
5-19Y, MH in the last 3 months, Yes700117
5-19Y, MH in the last 3 months, No3349413341112
20Y+, MT in past 14 days, Yes520070
20Y+, MT in past 14 days, No16611541332
20Y+, EDMT *, Ongoing00006
20Y+, EDMT *, 1-3 days510063
20Y+, EDMT *, ≥ 4days01001
20Y+, EDMT *, Missing/NA16611541332
20Y+, OM in past 14 days, Yes25331227
20Y+, OM in past 14 days, No14610231175
20Y+, DOM *, Ongoing530170
20Y+, DOM *, 1-7 days19030151
20Y+, DOM *, ≥ 8 days10006
20Y+, DOM *, Missing/NA14610231175
20Y+, MH in the last 3 months, Yes000012
20Y+, MH in the last 3 months, No17113541390
SecondaryNumber of Subjects With Anti-malarial Therapy in Survey 4, According to Parasite Density

The overall anti-malaria therapy data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg). Results include the following categories: Malaria treatment (MT) in past 14 days with sub-categories assessed: Yes, No; Exact days of malaria treatment (EDMT) with sub-categories assessed: Ongoing, 1-3 Days, ≥ 4 Days, Missing/NA; Other medication (OM) in past 14 days with sub-categories assessed: Yes, No; Days of other medication (DOM) with sub-categories assessed: Ongoing, 1-7 Days, ≥ 8 Days, Missing/NA; Malaria hospitalization (MH) in the last 3 months with sub-categories assessed: Yes, No. Missing/NA = Missing or Not Applicable.\* In case of several medication (malaria treatment or other medication) taken per subject, the maximum duration was computed for this study.

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Count of participants · Participants
Number of Subjects With Anti-malarial Therapy in Survey 4, According to Parasite Density
ParticipantsLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, MT in past 14 days, Yes521571
6M-4Y, MT in past 14 days, No1631011949777
6M-4Y, EDMT *, Ongoing210421
6M-4Y, EDMT *, 1-3 days311149
6M-4Y, EDMT *, ≥ 4days00001
6M-4Y, EDMT *, Missing/NA1631011949777
6M-4Y, OM in past 14 days, Yes2111712152
6M-4Y, OM in past 14 days, No147921342696
6M-4Y, DOM *, Ongoing523548
6M-4Y, DOM *, 1-7 days16847103
6M-4Y, DOM *, ≥ 8 days01001
6M-4Y, DOM *, Missing/NA147921342696
6M-4Y, MH in the last 3 months, Yes910228
6M-4Y, MH in the last 3 months, No1591022052820
5-19Y, MT in past 14 days, Yes200010
5-19Y, MT in past 14 days, No196511613318
5-19Y, EDMT *, Ongoing00003
5-19Y, EDMT *, 1-3 days20007
5-19Y, EDMT *, ≥ 4days00000
5-19Y, EDMT *, Missing/NA196511613318
5-19Y, OM in past 14 days, Yes1340228
5-19Y, OM in past 14 days, No185471611300
5-19Y, DOM *, Ongoing10016
5-19Y, DOM *, 1-7 days1240122
5-19Y, DOM *, ≥ 8 days00000
5-19Y, DOM *, Missing/NA185471611300
5-19Y, MH in the last 3 months, Yes00002
5-19Y, MH in the last 3 months, No198511613326
20Y+, MT in past 14 days, Yes10—08
20Y+, MT in past 14 days, No864—1500
20Y+, EDMT *, Ongoing00—01
20Y+, EDMT *, 1-3 days10—05
20Y+, EDMT *, ≥ 4days00—02
20Y+, EDMT *, Missing/NA864—1500
20Y+, OM in past 14 days, Yes50—057
20Y+, OM in past 14 days, No824—1451
20Y+, DOM *, Ongoing10—018
20Y+, DOM *, 1-7 days40—036
20Y+, DOM *, ≥ 8 days00—03
20Y+, DOM *, Missing/NA824—1451
20Y+, MH in the last 3 months, Yes00—05
20Y+, MH in the last 3 months, No874—1503
SecondaryMean Number of Days With Malaria Treatment at Survey 1

The mean and standard deviation of the number of days of malaria treatment (DMT) were calculated for the past 14 days period of treatment. The malaria treatment data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
During the 14 day-period before the malaria treatment
Reported as:
Mean · Days
Mean Number of Days With Malaria Treatment at Survey 1
DaysLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, DMT2.6 ± 1.023.7 ± 1.702.5 ± 0.713.1 ± 0.673.1 ± 1.45
5-19Y, DMT2.0 ± 0.822.2 ± 0.982.8 ± 0.503.5 ± 0.712.5 ± 1.09
20+Y, DMT1.0 ± 0.00———2.6 ± 1.37
SecondaryMean Number of Days With Malaria Treatment at Survey 2

The mean and standard deviation of the number of days of malaria treatment (DMT) were calculated for the past 14 days period of treatment. The malaria treatment data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
During the 14 day-period before the malaria treatment
Reported as:
Mean · Days
Mean Number of Days With Malaria Treatment at Survey 2
DaysLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, DMT2.8 ± 1.485.7 ± 2.313.5 ± 0.712.0 ± 1.153.1 ± 1.16
5-19Y, DMT2.8 ± 1.813.5 ± 2.123.0 ± 0.002.5 ± 1.002.5 ± 0.81
20+Y, DMT3.0 ± 0.00——1.0 ± 0.002.5 ± 1.37
SecondaryMean Number of Days With Malaria Treatment at Survey 3

The mean and standard deviation of the number of days of malaria treatment (DMT) were calculated for the past 14 days period of treatment. The malaria treatment data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
During the 14 day-period before the malaria treatment
Reported as:
Mean · Days
Mean Number of Days With Malaria Treatment at Survey 3
DaysLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, DMT3.0 ± 0.713.3 ± 1.072.3 ± 1.152.2 ± 1.103.1 ± 1.08
5-19Y, DMT3.9 ± 2.881.7 ± 1.153.0 ± 0.001.0 ± 0.002.9 ± 1.27
20+Y, DMT1.4 ± 0.895.0 ± 2.83——2.3 ± 1.12
SecondaryMean Number of Days With Malaria Treatment at Survey 4

The mean and standard deviation of the number of days of malaria treatment (DMT) were calculated for the past 14 days period of treatment. The malaria treatment data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
During the 14 day-period before the malaria treatment
Reported as:
Mean · Days
Mean Number of Days With Malaria Treatment at Survey 4
DaysLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, DMT2.3 ± 1.153.0 ± 0.003.0 ± 0.001.0 ± 0.003.1 ± 0.59
5-19Y, DMT3.0 ± 0.00———2.9 ± 0.38
20+Y, DMT1.0 ± 0.00———3.3 ± 2.14
SecondaryNumber of Subjects With Fever in the Last 24 Hours or at Visit During Survey 1

Measured characteristics of fever were the following: Fever in the last 24 hours (F 24h) and Fever at visit (F at V). Note: Fever set to "Yes" if temperature recorded after axillary conversion was ≥ 37.5 degrees Celsius (°C). Missing/NA = Missing or Not Applicable. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
In the last 24 hours or at the survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Fever in the Last 24 Hours or at Visit During Survey 1
ParticipantsLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, F 24h - Yes71532160361
6M-4Y, F 24h - No30211737592119
6M-4Y, F at V - Yes261372279
6M-4Y, F at V - No34715751972400
6M-4Y, F at V - Missing/NA00001
5-19Y, F 24h - Yes37251024124
5-19Y, F 24h - No2574613341043
5-19Y, F at V - Yes6551729
5-19Y, F at V - No2886618411138
20+Y, F 24h - Yes309—2181
20+Y, F 24h - No898—91260
20+Y, F at V - Yes30—123
20+Y, F at V - No11517—101418
20+Y, F at V - Missing/NA10—00
SecondaryNumber of Subjects With Fever in the Last 24 Hours or at Visit During Survey 2

Measured characteristics of fever were the following: Fever in the last 24 hours (F 24h) and Fever at visit (F at V). Note: Fever set to "Yes" if temperature recorded after axillary conversion was ≥ 37.5 degrees Celsius (°C). Missing/NA = Missing or Not Applicable. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
In the last 24 hours or at the survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Fever in the Last 24 Hours or at Visit During Survey 2
ParticipantsLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, F 24h - Yes41231535357
6M-4Y, F 24h - No24212552412266
6M-4Y, F at V - Yes2616152998
6M-4Y, F at V - No25713252472525
5-19Y, F 24h - Yes39111113115
5-19Y, F 24h - No2946018231043
5-19Y, F at V - Yes2443826
5-19Y, F at V - No3096726281132
20+Y, F 24h - Yes14432169
20+Y, F 24h - No1106251272
20+Y, F at V - Yes1000136
20+Y, F at V - No11410561404
20+Y, F at V - Missing/NA00001
SecondaryNumber of Subjects With Fever in the Last 24 Hours or at Visit During Survey 3

Measured characteristics of fever were the following: Fever in the last 24 hours (F 24h) and Fever at visit (F at V). Note: Fever set to "Yes" if temperature recorded after axillary conversion was ≥ 37.5 degrees Celsius (°C). Missing/NA = Missing or Not Applicable. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
In the last 24 hours or at the survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Fever in the Last 24 Hours or at Visit During Survey 3
ParticipantsLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, F 24h - Yes60442844360
6M-4Y, F 24h - No21911746472228
6M-4Y, F at V - Yes81692256
6M-4Y, F at V - No27114565692532
5-19Y, F 24h - Yes542541792
5-19Y, F 24h - No287699181037
5-19Y, F at V - Yes11611421
5-19Y, F at V - No3308712211107
5-19Y, F at V - Missing/NA01001
20+Y, F 24h - Yes20441167
20+Y, F 24h - No1519131235
20+Y, F at V - Yes503123
20+Y, F at V - No16613231378
20+Y, F at V - Missing/NA00001
SecondaryNumber of Subjects With Fever in the Last 24 Hours or at Visit During Survey 4

Measured characteristics of fever were the following: Fever in the last 24 hours (F 24h) and Fever at visit (F at V). Note: Fever set to "Yes" if temperature recorded after axillary conversion was ≥ 37.5 degrees Celsius (°C). Missing/NA = Missing or Not Applicable. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
In the last 24 hours or at the survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Fever in the Last 24 Hours or at Visit During Survey 4
ParticipantsLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, F 24h - Yes3918527115
6M-4Y, F 24h - No129851527733
6M-4Y, F at V - Yes8841820
6M-4Y, F at V - No160951636827
6M-4Y, F at V - Missing/NA00001
5-19Y, F 24h - Yes3884422
5-19Y, F 24h - No16043129306
5-19Y, F at V - Yes50214
5-19Y, F at V - No193511412324
20+Y, F 24h - Yes110—025
20+Y, F 24h - No764—1483
20+Y, F at V - Yes00—03
20+Y, F at V - No874—1505
SecondaryMean Number of Days With Fever at Survey 1

The mean and standard deviation of the number of days ago with fever start (DaFs) were calculated for subjects having fever in the last 24 hours. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Mean · Days
Mean Number of Days With Fever at Survey 1
DaysLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, DaFs2.5 ± 2.182.6 ± 2.232.1 ± 1.422.5 ± 4.132.3 ± 1.77
5-19Y, DaFs2.2 ± 1.412.2 ± 1.292.7 ± 2.061.7 ± 1.052.3 ± 1.93
20+Y, DaFs2.3 ± 1.562.3 ± 1.87—2.5 ± 0.712.9 ± 3.36
SecondaryMean Number of Days With Fever at Survey 2

The mean and standard deviation of the number of days ago with fever start (DaFs) were calculated for subjects having fever in the last 24 hours. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Mean · Days
Mean Number of Days With Fever at Survey 2
DaysLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, DaFs2.1 ± 1.352.7 ± 1.991.4 ± 0.512.0 ± 1.462.4 ± 1.76
5-19Y, DaFs2.5 ± 1.622.6 ± 2.382.5 ± 2.342.1 ± 1.802.1 ± 1.38
20+Y, DaFs4.0 ± 3.642.0 ± 1.152.0 ± 1.004.0 ± 2.833.2 ± 2.96
SecondaryMean Number of Days With Fever at Survey 3

The mean and standard deviation of the number of days ago with fever start (DaFs) were calculated for subjects having fever in the last 24 hours. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Mean · Days
Mean Number of Days With Fever at Survey 3
DaysLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, DaFs2.3 ± 1.902.4 ± 1.952.2 ± 1.332.1 ± 1.372.5 ± 1.80
5-19Y, DaFs2.3 ± 1.582.8 ± 1.632.5 ± 1.731.8 ± 0.532.7 ± 2.21
20+Y, DaFs3.0 ± 1.812.8 ± 0.503.8 ± 2.223.0 ± 0.003.3 ± 4.28
SecondaryMean Number of Days With Fever at Survey 4

The mean and standard deviation of the number of days ago with fever start (DaFs) were calculated for subjects having fever in the last 24 hours. Fever data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
During the survey period (approximatively 1 year)
Reported as:
Mean · Days
Mean Number of Days With Fever at Survey 4
DaysLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, DaFs2.2 ± 1.052.4 ± 2.431.6 ± 0.892.2 ± 1.642.7 ± 1.88
5-19Y, DaFs2.0 ± 0.973.8 ± 2.381.5 ± 0.582.0 ± 1.152.1 ± 1.23
20+Y, DaFs2.5 ± 1.21———3.2 ± 1.38
SecondaryAxillary Temperature at Visit in Survey 1

The mean and standard deviation of the axillary temperature at visit (A temp. at V) were calculated. Axillary temperature data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Mean · Degrees Celsius
Axillary Temperature at Visit in Survey 1
Degrees CelsiusLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, A temp. at V36.65 ± 0.52136.64 ± 0.62336.72 ± 0.78237.04 ± 0.80336.55 ± 0.522
5-19Y, A temp. at V36.56 ± 0.46936.70 ± 0.59737.07 ± 0.85337.29 ± 0.92836.63 ± 0.496
20+Y, A temp. at V36.55 ± 0.45936.70 ± 0.387—36.82 ± 0.46236.60 ± 0.478
SecondaryAxillary Temperature at Visit in Survey 2

The mean and standard deviation of axillary temperature at visit (A temp. at V) were calculated. Axillary temperature data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Mean · Degrees Celsius
Axillary Temperature at Visit in Survey 2
Degrees CelsiusLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, A temp. at V36.69 ± 0.57436.75 ± 0.62836.86 ± 0.72537.41 ± 1.20136.60 ± 0.479
5-19Y, A temp. at V36.70 ± 0.52236.76 ± 0.50736.76 ± 0.77337.36 ± 0.94936.66 ± 0.447
20+Y, A temp. at V36.70 ± 0.47836.75 ± 0.37536.64 ± 0.55937.09 ± 0.71336.67 ± 0.430
SecondaryAxillary Temperature at Visit in Survey 3

The mean and standard deviation of axillary temperature at visit (A temp. at V) were calculated. Axillary temperature data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Mean · Degrees Celsius
Axillary Temperature at Visit in Survey 3
Degrees CelsiusLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, A temp. at V36.47 ± 0.51736.66 ± 0.65236.68 ± 0.70136.97 ± 0.95136.54 ± 0.496
5-19Y, A temp. at V36.56 ± 0.55136.66 ± 0.57136.61 ± 0.47537.45 ± 1.11736.59 ± 0.462
20+Y, A temp. at V36.44 ± 0.51536.42 ± 0.40937.54 ± 1.13537.18 ± 0.72736.55 ± 0.493
SecondaryAxillary Temperature at Visit in Survey 4

The mean and standard deviation of axillary temperature at visit (A temp. at V) were calculated. Axillary temperature data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Mean · Degrees Celsius
Axillary Temperature at Visit in Survey 4
Degrees CelsiusLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, A temp. at V36.51 ± 0.50836.51 ± 0.53536.95 ± 0.92737.16 ± 1.18736.40 ± 0.492
5-19Y, A temp. at V36.53 ± 0.51036.55 ± 0.37936.53 ± 0.57036.61 ± 0.43136.38 ± 0.430
20+Y, A temp. at V36.42 ± 0.44436.68 ± 0.206—36.50 ± 0.00036.39 ± 0.457
SecondaryNumber of Subjects Living in the Same House at Survey 1

The malaria prevention and risk factors characteristics were: Number of persons living in the same part of the house (PLSPH) among persons enrolled in the study (PES), in the following combinations: \< y/x (less than \[\<\] y PLSPH among x PES), y-z/x (y to z PLSPH among x PES), \> z/x (more than \[\>\] z PLSPH among x PES), y-z/\> x (y to z PLSPH among more than \[\>\] x PES), \> z/\> x (more than \[\>\] z PLSPH among more than \[\>\] x PES, or missing information). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Living in the Same House at Survey 1
ParticipantsLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, PLSPH/PES, <3/134133278
6M-4Y, PLSPH/PES, 4-5/1321512146
6M-4Y, PLSPH/PES, >5/1201003123
6M-4Y, PLSPH/PES, <3/24614614280
6M-4Y, PLSPH/PES, 4-5/2106491336737
6M-4Y, PLSPH/PES, >5/21195928591038
6M-4Y, PLSPH/PES, <3/310003
6M-4Y, PLSPH/PES, 4-5/3111119
6M-4Y, PLSPH/PES, >5/31374145
6M-4Y, PLSPH/PES, 4-5/>300101
6M-4Y, PLSPH/PES, >5/>312119
6M-4Y, Missing00001
5-19Y, PLSPH/PES, <3/12060028
5-19Y, PLSPH/PES, 4-5/11421117
5-19Y, PLSPH/PES, >5/1831037
5-19Y, PLSPH/PES, <3/21941575
5-19Y, PLSPH/PES, 4-5/27613917357
5-19Y, PLSPH/PES, >5/2111381034560
5-19Y, PLSPH/PES, <3/301002
5-19Y, PLSPH/PES, 4-5/31010014
5-19Y, PLSPH/PES, >5/32521159
5-19Y, PLSPH/PES, 4-5/>310000
5-19Y, PLSPH/PES, >5/>31010017
5-19Y, Missing00001
20+Y, PLSPH/PES, <3/130—049
20+Y, PLSPH/PES, 4-5/110—016
20+Y, PLSPH/PES, >5/161—026
20+Y, PLSPH/PES, <3/2222—2234
20+Y, PLSPH/PES, 4-5/2407—3449
20+Y, PLSPH/PES, >5/2337—6575
20+Y, PLSPH/PES, <3/300—02
20+Y, PLSPH/PES, 4-5/330—018
20+Y, PLSPH/PES, >5/3100—051
20+Y, PLSPH/PES, 4-5/>300—01
20+Y, PLSPH/PES, >5/>310—018
20+Y, Missing00—02
SecondaryNumber of Subjects Living in the Same House at Survey 2

The malaria prevention and risk factors characteristics were: Number of persons living in the same part of the house (PLSPH) among persons enrolled in the study (PES), in the following combinations: \< y/x (less than \[\<\] y PLSPH among x PES), y-z/x (y to z PLSPH among x PES), \> z/x (more than \[\>\] z PLSPH among x PES), y-z/\> x (y to z PLSPH among more than \[\>\] x PES), \> z/\> x (more than \[\>\] z PLSPH among more than \[\>\] x PES, or missing information). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Living in the Same House at Survey 2
ParticipantsLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, PLSPH/PES, <3/127188259
6M-4Y, PLSPH/PES, 4-5/1331883112
6M-4Y, PLSPH/PES, >5/11393484
6M-4Y, PLSPH/PES, <3/23721814306
6M-4Y, PLSPH/PES, 4-5/293481724964
6M-4Y, PLSPH/PES, >5/2763219271059
6M-4Y, PLSPH/PES, <3/310002
6M-4Y, PLSPH/PES, 4-5/3000011
6M-4Y, PLSPH/PES, >5/3314224
6M-4Y, PLSPH/PES, 4-5/>300002
6M-4Y, PLSPH/PES, >5/>301000
5-19Y, PLSPH/PES, <3/13431323
5-19Y, PLSPH/PES, 4-5/130132020
5-19Y, PLSPH/PES, >5/11630038
5-19Y, PLSPH/PES, <3/23030269
5-19Y, PLSPH/PES, 4-5/298171013426
5-19Y, PLSPH/PES, >5/2105281517548
5-19Y, PLSPH/PES, <3/320001
5-19Y, PLSPH/PES, 4-5/340009
5-19Y, PLSPH/PES, >5/31441120
5-19Y, PLSPH/PES, 4-5/>300004
5-19Y, PLSPH/PES, >5/>300000
20+Y, PLSPH-PES, <3/11400040
20+Y, PLSPH/PES, 4-5/1800026
20+Y, PLSPH/PES, >5/1501051
20+Y, PLSPH/PES, <3/234212253
20+Y, PLSPH/PES, 4-5/239302553
20+Y, PLSPH/PES, >5/221533476
20+Y, PLSPH/PES, <3/300003
20+Y, PLSPH/PES, 4-5/300009
20+Y, PLSPH/PES, >5/3300025
20+Y, PLSPH/PES, 4-5/>300002
20+Y, PLSPH/PES, >5/>300003
SecondaryNumber of Subjects Living in the Same House at Survey 3

The malaria prevention and risk factors characteristics were: Number of persons living in the same part of the house (PLSPH) among persons enrolled in the study (PES), in the following combinations: \< y/x (less than \[\<\] y PLSPH among x PES), y-z/x (y to z PLSPH among x PES), \> z/x (more than \[\>\] z PLSPH among x PES), y-z/\> x (y to z PLSPH among more than \[\>\] x PES), \> z/\> x (more than \[\>\] z PLSPH among more than \[\>\] x PES, or missing information). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Living in the Same House at Survey 3
ParticipantsLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, PLSPH/PES, <3/1311671163
6M-4Y, PLSPH/PES, 4-5/1312681194
6M-4Y, PLSPH/PES, >5/115106294
6M-4Y, PLSPH/PES, <3/243241317340
6M-4Y, PLSPH/PES, 4-5/276301922973
6M-4Y, PLSPH/PES, >5/275441926984
6M-4Y, PLSPH/PES, <3/300000
6M-4Y, PLSPH/PES, 4-5/3201011
6M-4Y, PLSPH/PES, >5/36111229
6M-4Y, PLSPH/PES, 4-5/>300000
6M-4Y, PLSPH/PES, >5/>300000
5-19Y, PLSPH/PES, <3/14091124
5-19Y, PLSPH/PES, 4-5/13280123
5-19Y, PLSPH/PES, >5/13110342
5-19Y, PLSPH/PES, <3/224130288
5-19Y, PLSPH/PES, 4-5/27425513421
5-19Y, PLSPH/PES, >5/210336715507
5-19Y, PLSPH/PES, <3/300000
5-19Y, PLSPH/PES, 4-5/370007
5-19Y, PLSPH/PES, >5/33020017
5-19Y, PLSPH/PES, 4-5/>300000
5-19Y, PLSPH/PES, >5/>300000
20+Y, PLSPH/PES, <3/11800040
20+Y, PLSPH/PES, 4-5/1700027
20+Y, PLSPH/PES, >5/1500033
20+Y, PLSPH/PES, <3/243301273
20+Y, PLSPH/PES, 4-5/257430516
20+Y, PLSPH/PES, >5/228623463
20+Y, PLSPH/PES, <3/300000
20+Y, PLSPH/PES, 4-5/3000014
20+Y, PLSPH/PES, >5/31300036
20+Y, PLSPH/PES, 4-5/>300000
20+Y, PLSPH/PES, >5/>300000
SecondaryNumber of Subjects Living in the Same House at Survey 4

The malaria prevention and risk factors characteristics were: Number of persons living in the same part of the house (PLSPH) among persons enrolled in the study (PES), in the following combinations: \< y/x (less than \[\<\] y PLSPH among x PES), y-z/x (y to z PLSPH among x PES), \> z/x (more than \[\>\] z PLSPH among x PES), y-z/\> x (y to z PLSPH among more than \[\>\] x PES), \> z/\> x (more than \[\>\] z PLSPH among more than \[\>\] x PES, or missing information). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Living in the Same House at Survey 4
ParticipantsLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, PLSPH/PES, <3/128212742
6M-4Y, PLSPH/PES, 4-5/124144574
6M-4Y, PLSPH/PES, >5/11871559
6M-4Y, PLSPH/PES, <3/2271831074
6M-4Y, PLSPH/PES, 4-5/23023313184
6M-4Y, PLSPH/PES, >5/22512412338
6M-4Y, PLSPH-PES, <3/300101
6M-4Y, PLSPH/PES, 4-5/311019
6M-4Y, PLSPH/PES, >5/31472162
6M-4Y, PLSPH/PES, 4-5/>300001
6M-4Y, PLSPH/PES, >5/>310004
5-19Y, PLSPH/PES, <3/13652217
5-19Y, PLSPH/PES, 4-5/135111223
5-19Y, PLSPH/PES, >5/142217
5-19Y, PLSPH/PES, <3/21352010
5-19Y, PLSPH/PES, 4-5/22783365
5-19Y, PLSPH/PES, >5/2311034149
5-19Y, PLSPH/PES, <3/300000
5-19Y, PLSPH/PES, 4-5/3510012
5-19Y, PLSPH/PES, >5/34293138
5-19Y, PLSPH/PES, 4-5/>300002
5-19Y, PLSPH/PES, >5/>350005
20+Y, PLSPH/PES, <3/140—020
20+Y, PLSPH/PES, 4-5/140—08
20+Y, PLSPH/PES, >5/110—010
20+Y, PLSPH/PES, <3/2230—081
20+Y, PLSPH/PES, 4-5/2262—0119
20+Y, PLSPH/PES, >5/2151—0191
20+Y, PLSPH/PES, <3/310—03
20+Y, PLSPH/PES, 4-5/320—13
20+Y, PLSPH/PES, >5/3111—067
20+Y, PLSPH/PES, 4-5/>300—01
20+Y, PLSPH/PES, >5/>300—05
SecondaryMean Number of Subjects Living in the Same House at Survey 1

The malaria prevention and risk factors characteristics were the following: the mean and standard deviation of the number of persons living in the same part of the house (PLSPH). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Mean · Persons
Mean Number of Subjects Living in the Same House at Survey 1
PersonsLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, PLSPH6.4 ± 4.836.3 ± 4.236.5 ± 3.985.8 ± 2.146.5 ± 4.28
5-19Y, PLSPH6.9 ± 4.556.6 ± 3.535.9 ± 1.916.5 ± 3.047.1 ± 4.69
20+Y, PLSPH6.1 ± 4.157.4 ± 5.21—6.2 ± 2.996.3 ± 4.24
SecondaryMean Number of Subjects Living in the Same House at Survey 2

The malaria prevention and risk factors characteristics were the following: the mean and standard deviation of the number of persons living in the same part of the house (PLSPH). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Mean · Persons
Mean Number of Subjects Living in the Same House at Survey 2
PersonsLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, PLSPH5.1 ± 2.905.0 ± 2.175.1 ± 2.345.4 ± 2.625.8 ± 2.66
5-19Y, PLSPH5.5 ± 2.646.1 ± 2.785.9 ± 1.895.9 ± 2.816.2 ± 2.78
20+Y, PLSPH4.7 ± 3.356.5 ± 3.247.8 ± 3.275.3 ± 2.565.4 ± 2.64
SecondaryMean Number of Subjects Living in the Same House at Survey 3

The malaria prevention and risk factors characteristics were the following: the mean and standard deviation of the number of persons living in the same part of the house (PLSPH). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Mean · Persons
Mean Number of Subjects Living in the Same House at Survey 3
PersonsLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, PLSPH5.1 ± 2.735.4 ± 2.745.1 ± 3.405.0 ± 2.435.6 ± 2.48
5-19Y, PLSPH5.9 ± 3.255.1 ± 2.045.5 ± 1.855.8 ± 2.066.0 ± 2.42
20+Y, PLSPH4.5 ± 2.165.9 ± 3.235.4 ± 1.146.5 ± 2.895.4 ± 2.77
SecondaryMean Number of Subjects Living in the Same House at Survey 4

The malaria prevention and risk factors characteristics were the following: the mean and standard deviation of the number of persons living in the same part of the house (PLSPH). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Mean · Persons
Mean Number of Subjects Living in the Same House at Survey 4
PersonsLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, PLSPH5.4 ± 3.125.1 ± 3.735.5 ± 3.505.2 ± 3.246.6 ± 3.33
5-19Y, PLSPH6.5 ± 4.556.1 ± 3.956.3 ± 3.136.8 ± 4.287.3 ± 3.70
20+Y, PLSPH5.0 ± 2.946.3 ± 2.22—5.0 ± 0.006.6 ± 3.96
SecondaryNumber of Subjects by Localisation and Type of Location at Survey 1

The malaria prevention and risk factors characteristics were the following: localisation categories (i.e.: rural, urban, semi-rural or missing) and Type of Location (i.e.: Large city: \>1 million habitants; Small city: \>50000 \& \< 1 million habitants; Town: \> 10000 and \< 50000 habitants; Countryside: \< 10000 habitants or missing type of location). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects by Localisation and Type of Location at Survey 1
ParticipantsLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, rural309136451061415
6M-4Y, urban39221011803
6M-4Y, semi-rural251232262
6M-4Y, missing - localisation00000
6M-4Y, large city181477355
6M-4Y, small city000018
6M-4Y, town441656644
6M-4Y, countryside311140461061463
5-19Y, rural225551651688
5-19Y, urban501345350
5-19Y, semi-rural19332128
5-19Y, missing - localisation00001
5-19Y, large city25544162
5-19Y, small city10007
5-19Y, town431123282
5-19Y, countryside225551751715
5-19Y, missing - type of localisation00001
20+Y, rural8912—10923
20+Y, urban263—0370
20+Y, semi-rural42—1147
20+Y, missing - localisation00—01
20+Y, large city163—0181
20+Y, small city00—09
20+Y, town142—1299
20+Y, countryside8912—10951
20+Y, missing - type of localisation00—01
SecondaryNumber of Subjects by Localisation and Type of Location at Survey 2

The malaria prevention and risk factors characteristics were the following: localisation categories (i.e.: rural, urban, semi-rural) and Type of Location (i.e.: Large city: \>1 million habitants; Small city: \>50000 \& \< 1 million habitants; Town: \> 10000 and \< 50000 habitants; Countryside: \< 10000 habitants). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects by Localisation and Type of Location at Survey 2
ParticipantsLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, rural21212051601377
6M-4Y, urban44161415995
6M-4Y, semi-rural271221251
6M-4Y, large city10456374
6M-4Y, small city00006
6M-4Y, town341299632
6M-4Y, countryside23913253611611
5-19Y, rural237481725583
5-19Y, urban72221110472
5-19Y, semi-rural24111103
5-19Y, large city15527172
5-19Y, small city00001
5-19Y, town571793305
5-19Y, countryside261491826680
20+Y, rural94626769
20+Y, urban26431515
20+Y, semi-rural4000157
20+Y, large city6201191
20+Y, small city00005
20+Y, town20230330
20+Y, countryside98626915
SecondaryNumber of Subjects by Localisation and Type of Location at Survey 3

The malaria prevention and risk factors characteristics were the following: localisation categories (i.e.: rural, urban, semi-rural) and Type of Location (i.e.: Large city: \>1 million habitants; Small city: \>50000 \& \< 1 million habitants; Town: \> 10000 and \< 50000 habitants; Countryside: \< 10000 habitants). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects by Localisation and Type of Location at Survey 3
ParticipantsLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, rural23414665821531
6M-4Y, urban301155881
6M-4Y, semi-rural15444176
6M-4Y, large city7313386
6M-4Y, small city00002
6M-4Y, town23942541
6M-4Y, countryside24914969861659
5-19Y, rural28378928645
5-19Y, urban421247404
5-19Y, semi-rural1640080
5-19Y, large city12222182
5-19Y, small city00001
5-19Y, town301025241
5-19Y, countryside29982928705
20+Y, rural147853868
20+Y, urban23301430
20+Y, semi-rural1200104
20+Y, large city15000185
20+Y, small city00001
20+Y, town8301273
20+Y, countryside1481053943
SecondaryNumber of Subjects by Localisation and Type of Location at Survey 4

The malaria prevention and risk factors characteristics were the following: localisation categories (i.e.: rural, urban, semi-rural) and Type of Location (i.e.: Large city: \>1 million habitants; Small city: \>50000 \& \< 1 million habitants; Town: \> 10000 and \< 50000 habitants; Countryside: \< 10000 habitants). Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects by Localisation and Type of Location at Survey 4
ParticipantsLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, rural1531022053536
6M-4Y, urban15101312
6M-4Y, semi-rural00000
6M-4Y, large city00000
6M-4Y, small city00000
6M-4Y, town15101311
6M-4Y, countryside1531022053537
5-19Y, rural184491411186
5-19Y, urban14222142
5-19Y, semi-rural00000
5-19Y, large city00000
5-19Y, small city00000
5-19Y, town14222141
5-19Y, countryside184491411187
20+Y, rural854—1352
20+Y, urban20—0156
20+Y, semi-rural00—00
20+Y, large city00—00
20+Y, small city00—00
20+Y, town20—0155
20+Y, countryside854—1353
SecondaryNumber of Subjects by House Construction Material Regarding Walls and Floor at Survey 1

The malaria prevention and risk factors characteristics were the following: Main house construction material (MHCM) walls and MHCM floor. MHCM walls data were assessed for the following sub-categories: mud, brick, cement/plaster, cement/paint, other and missing. MHCM floor data were assessed for the following sub-categories: natural floor, rudimentary floor, parquet polished wood, vinyl or asphalt strips, ceramic tiles, cement, carpet, missing. Note: Natural floor = earth, sand, dung; Rudimentary floor = wood planks, palm, bamboo. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects by House Construction Material Regarding Walls and Floor at Survey 1
ParticipantsLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, MHCM walls - mud97623484869
6M-4Y, MHCM walls - brick190761212504
6M-4Y, MHCM walls - cement/plaster4116711383
6M-4Y, MHCM walls - cement/paint2912511408
6M-4Y, MHCM walls - other16401316
6M-4Y, MHCM floor - natural floor19710042831079
6M-4Y, MHCM floor - rudimentary floor00003
6M-4Y, MHCM floor - parquet polished wood00002
6M-4Y, MHCM floor - vinyl/asphalt strips00004
6M-4Y, MHCM floor - ceramic tiles010030
6M-4Y, MHCM floor - cement1706916331309
6M-4Y, MHCM floor - carpet600353
5-19Y, MHCM walls - mud89291348424
5-19Y, MHCM walls - brick1192334223
5-19Y, MHCM walls - cement/plaster43845168
5-19Y, MHCM walls - cement/paint30431186
5-19Y, MHCM walls - other13700165
5-19Y, MHCM walls - missing00001
5-19Y, MHCM floor - natural floor146461248511
5-19Y, MHCM floor - rudimentary floor00001
5-19Y, MHCM floor - parquet polished wood00001
5-19Y, MHCM floor - vinyl/asphalt strips00002
5-19Y, MHCM floor - ceramic tiles010014
5-19Y, MHCM floor - cement146241110607
5-19Y, MHCM floor - carpet200030
5-19Y, MHCM floor - missing00001
20+Y, MHCM walls - mud437—9548
20+Y, MHCM walls - brick432—0337
20+Y, MHCM walls - cement/plaster125—1192
20+Y, MHCM walls - cement/paint163—0217
20+Y, MHCM walls - other50—1146
20+Y, MHCM walls - missing00—01
20+Y, MHCM floor - natural floor645—8690
20+Y, MHCM floor - rudimentary floor00—02
20+Y, MHCM floor - parquet polished wood00—01
20+Y, MHCM floor - vinyl/asphalt strips00—02
20+Y, MHCM floor - ceramic tiles00—013
20+Y, MHCM floor - cement5511—3705
20+Y, MHCM floor - carpet01—027
20+Y, MHCM floor - missing00—01
SecondaryNumber of Subjects by House Construction Material Regarding Walls and Floor at Survey 2

The malaria prevention and risk factors characteristics were the following: Main house construction material (MHCM) walls and MHCM floor. MHCM walls data were assessed for the following sub-categories: mud, brick, cement/plaster, cement/paint, other. MHCM floor data were assessed for the following sub-categories: natural floor, rudimentary floor, parquet polished wood, vinyl or asphalt strips, ceramic tiles, cement, carpet. Note: Natural floor = earth, sand, dung; Rudimentary floor = wood planks, palm, bamboo. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects by House Construction Material Regarding Walls and Floor at Survey 2
ParticipantsLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, MHCM walls - mud493015291010
6M-4Y, MHCM walls - brick163813431458
6M-4Y, MHCM walls - cement/plaster331488472
6M-4Y, MHCM walls - cement/paint321542393
6M-4Y, MHCM walls - other6866290
6M-4Y, MHCM floor - natural floor1949745531145
6M-4Y, MHCM floor - rudimentary floor00002
6M-4Y, MHCM floor - parquet polished wood00106
6M-4Y, MHCM floor - vinyl/asphalt strips000015
6M-4Y, MHCM floor - ceramic tiles010140
6M-4Y, MHCM floor - cement845020221357
6M-4Y, MHCM floor - carpet501058
5-19Y, MHCM walls - mud79201121445
5-19Y, MHCM walls - brick15526117191
5-19Y, MHCM walls - cement/plaster511524207
5-19Y, MHCM walls - cement/paint34510182
5-19Y, MHCM walls - other14544133
5-19Y, MHCM floor - natural floor207421726508
5-19Y, MHCM floor - rudimentary floor10000
5-19Y, MHCM floor - parquet polished wood00105
5-19Y, MHCM floor - vinyl/asphalt strips000010
5-19Y, MHCM floor - ceramic tiles000026
5-19Y, MHCM floor - cement11729119587
5-19Y, MHCM floor - carpet800122
20+Y, MHCM walls - mud26515520
20+Y, MHCM walls - brick69200302
20+Y, MHCM walls - cement/plaster7011258
20+Y, MHCM walls - cement/paint15000215
20+Y, MHCM walls - other7331146
20+Y, MHCM floor - natural floor88725653
20+Y, MHCM floor - rudimentary floor00001
20+Y, MHCM floor - parquet polished wood00001
20+Y, MHCM floor - vinyl/asphalt strips00104
20+Y, MHCM floor - ceramic tiles100015
20+Y, MHCM floor - cement34322732
20+Y, MHCM floor - carpet100035
SecondaryNumber of Subjects by House Construction Material Regarding Walls and Floor at Survey 3

The malaria prevention and risk factors characteristics were the following: Main house construction material (MHCM) walls and MHCM floor. MHCM walls data were assessed for the following sub-categories: mud, brick, cement/plaster, cement/paint, other. MHCM floor data were assessed for the following sub-categories: natural floor, rudimentary floor, ceramic tiles, cement, carpet. Note: Natural floor = earth, sand, dung; Rudimentary floor = wood planks, palm, bamboo. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects by House Construction Material Regarding Walls and Floor at Survey 3
ParticipantsLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, MHCM walls - mud65421933969
6M-4Y, MHCM walls - brick143914143485
6M-4Y, MHCM walls - cement/plaster2310105350
6M-4Y, MHCM walls - cement/paint281235464
6M-4Y, MHCM walls - other20615320
6M-4Y, MHCM floor - natural floor18811154651082
6M-4Y, MHCM floor - rudimentary floor00004
6M-4Y, MHCM floor - ceramic tiles100026
6M-4Y, MHCM floor - cement854920251406
6M-4Y, MHCM floor - carpet510170
5-19Y, MHCM walls - mud9032413432
5-19Y, MHCM walls - brick16142212205
5-19Y, MHCM walls - cement/plaster38813136
5-19Y, MHCM walls - cement/paint41522214
5-19Y, MHCM walls - other11745142
5-19Y, MHCM floor - natural floor18567724449
5-19Y, MHCM floor - rudimentary floor01000
5-19Y, MHCM floor - ceramic tiles200012
5-19Y, MHCM floor - cement14926611636
5-19Y, MHCM floor - carpet500032
20+Y, MHCM walls - mud46343520
20+Y, MHCM walls - brick90400298
20+Y, MHCM walls - cement/plaster10010188
20+Y, MHCM walls - cement/paint15100228
20+Y, MHCM walls - other10501168
20+Y, MHCM floor - natural floor124943651
20+Y, MHCM floor - rudimentary floor00002
20+Y, MHCM floor - ceramic tiles010012
20+Y, MHCM floor - cement46311699
20+Y, MHCM floor - carpet100038
SecondaryNumber of Subjects by House Construction Material Regarding Walls and Floor at Survey 4

The malaria prevention and risk factors characteristics were the following: Main house construction material (MHCM) walls and MHCM floor. MHCM walls data were assessed for the following sub-categories: mud, brick, cement/plaster, cement/paint, other. MHCM floor data were assessed for the following sub-categories: natural floor, rudimentary floor, vinyl or asphalt strips, ceramic tiles, cement, carpet. Note: Natural floor = earth, sand, dung; Rudimentary floor = wood planks, palm, bamboo. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects by House Construction Material Regarding Walls and Floor at Survey 4
ParticipantsLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, MHCM walls - mud3314214127
6M-4Y, MHCM walls - brick92761733231
6M-4Y, MHCM walls - cement/plaster23812120
6M-4Y, MHCM walls - cement/paint620181
6M-4Y, MHCM walls - other14304289
6M-4Y, MHCM floor - natural floor97761537267
6M-4Y, MHCM floor - rudimentary floor01000
6M-4Y, MHCM floor - vinyl/asphalt strips00002
6M-4Y, MHCM floor - ceramic tiles010016
6M-4Y, MHCM floor - cement7023516541
6M-4Y, MHCM floor - carpet120122
5-19Y, MHCM walls - mud4040236
5-19Y, MHCM walls - brick114279578
5-19Y, MHCM walls - cement/plaster24114152
5-19Y, MHCM walls - cement/paint1341030
5-19Y, MHCM walls - other7525132
5-19Y, MHCM floor - natural floor105279696
5-19Y, MHCM floor - rudimentary floor00000
5-19Y, MHCM floor - vinyl/asphalt strips00001
5-19Y, MHCM floor - ceramic tiles00009
5-19Y, MHCM floor - cement892477214
5-19Y, MHCM floor - carpet40008
20+Y, MHCM walls - mud180—176
20+Y, MHCM walls - brick521—0171
20+Y, MHCM walls - cement/plaster132—070
20+Y, MHCM walls - cement/paint10—038
20+Y, MHCM walls - other31—0153
20+Y, MHCM floor - natural floor501—0201
20+Y, MHCM floor - rudimentary floor00—01
20+Y, MHCM floor - vinyl/asphalt strips00—01
20+Y, MHCM floor - ceramic tiles00—08
20+Y, MHCM floor - cement373—1287
20+Y, MHCM floor - carpet00—010
SecondaryNumber of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 1

The malaria prevention and risk factors characteristics were the following: main house construction material (MHCM) roof, windows/eaves, nets. MHCM roof data were assessed for the following sub-categories: grass/palm, iron sheet, tiles, other, missing. MHCM windows/eaves data were assessed for the following sub-categories: closed, open, partially open, missing. MHCM nets data were assessed for the following sub-categories: nets not present, nets present on all windows, nets present on some windows, missing. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 1
ParticipantsLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, MHCM roof - grass/palm112532244453
6M-4Y, MHCM roof - iron sheet23110935741980
6M-4Y, MHCM roof - tiles00007
6M-4Y, MHCM roof - other3081140
6M-4Y, MHCM windows/eaves - closed1939331771467
6M-4Y, MHCM windows/eaves - open76331720486
6M-4Y, MHCM windows/eaves - partially open104441022527
6M-4Y, MHCM windows/eaves - missing00000
6M-4Y, MHCM, nets - not present32215754911795
6M-4Y, MHCM, nets - present on all windows266121450
6M-4Y, MHCM, nets - present on some windows25737235
5-19Y, MHCM roof - grass/palm8819728212
5-19Y, MHCM roof - iron sheet193481630944
5-19Y, MHCM roof - tiles00002
5-19Y, MHCM roof - other134008
5-19Y, MHCM roof - missing00001
5-19Y, MHCM windows/eaves - closed154441438669
5-19Y, MHCM windows/eaves - open711659233
5-19Y, MHCM windows/eaves - partially open6911411264
5-19Y, MHCM windows/eaves - missing00001
5-19Y, MHCM, nets - not present256632142853
5-19Y, MHCM, nets - present on all windows226111197
5-19Y, MHCM, nets - present on some windows16215116
5-19Y, MHCM, nets - missing00001
20+Y, MHCM roof - grass/palm315—3280
20+Y, MHCM roof - iron sheet8412—81117
20+Y, MHCM roof - tiles00—06
20+Y, MHCM roof - other40—037
20+Y, MHCM roof - missing00—01
20+Y, MHCM windows/eaves - closed658—5798
20+Y, MHCM windows/eaves - open255—2291
20+Y, MHCM windows/eaves - partially open294—4351
20+Y, MHCM windows/eaves - missing00—01
20+Y, MHCM, nets - not present10712—71081
20+Y, MHCM, nets - present on all windows83—2223
20+Y, MHCM, nets - present on some windows42—2136
20+Y, MHCM, nets - missing00—01
SecondaryNumber of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 2

The malaria prevention and risk factors characteristics were the following: main house construction material (MHCM) roof, windows/eaves, nets. MHCM roof data were assessed for the following sub-categories: grass/palm, iron sheet, tiles, other. MHCM windows/eaves data were assessed for the following sub-categories: closed, open, partially open. MHCM nets data were assessed for the following sub-categories: nets not present, nets present on all windows, nets present on some windows. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 2
ParticipantsLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, MHCM roof - grass/palm52321623509
6M-4Y, MHCM roof - iron sheet20110246502092
6M-4Y, MHCM roof - tiles00001
6M-4Y, MHCM roof - other30145321
6M-4Y, MHCM windows/eaves - closed975430391411
6M-4Y, MHCM windows/eaves - open88452019669
6M-4Y, MHCM windows/eaves - partially open98491718543
6M-4Y, MHCM, nets - not present24213662661843
6M-4Y, MHCM, nets - present on all windows26648626
6M-4Y, MHCM, nets - present on some windows15612154
5-19Y, MHCM roof - grass/palm7615313207
5-19Y, MHCM roof - iron sheet241542623940
5-19Y, MHCM roof - tiles00000
5-19Y, MHCM roof - other1620011
5-19Y, MHCM windows/eaves - closed159361614610
5-19Y, MHCM windows/eaves - open8524617294
5-19Y, MHCM windows/eaves - partially open891175254
5-19Y, MHCM, nets - not present290652328793
5-19Y, MHCM, nets - present on all windows36536296
5-19Y, MHCM, nets - present on some windows713269
20+Y, MHCM roof - grass/palm30312276
20+Y, MHCM roof - iron sheet807451144
20+Y, MHCM roof - tiles10002
20+Y, MHCM roof - other1300019
20+Y, MHCM windows/eaves - closed49634732
20+Y, MHCM windows/eaves - open42322372
20+Y, MHCM windows/eaves - partially open33101337
20+Y, MHCM, nets - not present1159341033
20+Y, MHCM, nets - present on all windows5023320
20+Y, MHCM, nets - present on some windows410088
SecondaryNumber of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 3

The malaria prevention and risk factors characteristics were the following: main house construction material (MHCM) roof, windows/eaves, nets. MHCM roof data were assessed for the following sub-categories: grass/palm, iron sheet, tiles, other. MHCM windows/eaves data were assessed for the following sub-categories: closed, open, partially open. MHCM nets data were assessed for the following sub-categories: nets not present, nets present on all windows, nets present on some windows. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 3
ParticipantsLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, MHCM roof - grass/palm55351226464
6M-4Y, MHCM roof - iron sheet21412560632111
6M-4Y, MHCM roof - tiles00019
6M-4Y, MHCM roof - other101214
6M-4Y, MHCM windows/eaves - closed1648238571352
6M-4Y, MHCM windows/eaves - open86672830845
6M-4Y, MHCM windows/eaves - partially open291284391
6M-4Y, MHCM, nets - not present24414963841918
6M-4Y, MHCM, nets - present on all windows211064532
6M-4Y, MHCM, nets - present on some windows14253138
5-19Y, MHCM roof - grass/palm761615186
5-19Y, MHCM roof - iron sheet264771230940
5-19Y, MHCM roof - tiles00001
5-19Y, MHCM roof - other11002
5-19Y, MHCM windows/eaves - closed16558918593
5-19Y, MHCM windows/eaves - open14326216357
5-19Y, MHCM windows/eaves - partially open331021179
5-19Y, MHCM, nets - not present290831328818
5-19Y, MHCM, nets - present on all windows31904261
5-19Y, MHCM, nets - present on some windows2020350
20+Y, MHCM roof - grass/palm45122259
20+Y, MHCM roof - iron sheet12312321123
20+Y, MHCM roof - tiles00009
20+Y, MHCM roof - other300011
20+Y, MHCM windows/eaves - closed112941715
20+Y, MHCM windows/eaves - open49213483
20+Y, MHCM windows/eaves - partially open10200204
20+Y, MHCM, nets - not present15312441052
20+Y, MHCM, nets - present on all windows11000262
20+Y, MHCM, nets - present on some windows711088
SecondaryNumber of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 4

The malaria prevention and risk factors characteristics were the following: main house construction material (MHCM) roof, windows/eaves, nets. MHCM roof data were assessed for the following sub-categories: grass/palm, iron sheet, other. MHCM windows/eaves data were assessed for the following sub-categories: closed, open, partially open. MHCM nets data were assessed for the following sub-categories: nets not present, nets present on all windows, nets present on some windows. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Classified by House Construction Material Regarding Roof, Window/Eaves and Nets at Survey 4
ParticipantsLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, MHCM roof - grass/palm5129617161
6M-4Y, MHCM roof - iron sheet111671428673
6M-4Y, MHCM roof - other670914
6M-4Y, MHCM windows/eaves - closed124581334725
6M-4Y, MHCM windows/eaves - open15131566
6M-4Y, MHCM windows/eaves - partially open293261557
6M-4Y, MHCM, nets - not present156951651712
6M-4Y, MHCM, nets - present on all windows812279
6M-4Y, MHCM, nets - present on some windows472157
5-19Y, MHCM roof - grass/palm55101251
5-19Y, MHCM roof - iron sheet13437139276
5-19Y, MHCM roof - other94221
5-19Y, MHCM windows/eaves - closed13932119292
5-19Y, MHCM windows/eaves - open2484117
5-19Y, MHCM windows/eaves - partially open35111319
5-19Y, MHCM, nets - not present162411413276
5-19Y, MHCM, nets - present on all windows1752025
5-19Y, MHCM, nets - present on some windows1950027
20+Y, MHCM roof - grass/palm270—198
20+Y, MHCM roof - iron sheet564—0394
20+Y, MHCM roof - other40—116
20+Y, MHCM windows/eaves - closed644—1421
20+Y, MHCM windows/eaves - open90—033
20+Y, MHCM windows/eaves - partially open140—054
20+Y, MHCM, nets - not present744—1438
20+Y, MHCM, nets - present on all windows70—032
20+Y, MHCM, nets - present on some windows60—038
SecondaryNumber of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 1

The malaria prevention and risk factors characteristics were the following: Main source of drinking water (MSDW): bottled water, closed water source (piped water, tube well, dug well, protected well), open water source (unprotected well, spring water, rainwater, tanker truck, surface water), missing; and Presence of electricity (PE): Yes, No, missing. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 1
ParticipantsLow PD Group (Survey 1)Medium PD Group (Survey 1)High PD Group (Survey 1)Very High PD Group (Survey 1)Neg PD Group (Survey 1)
6M-4Y, MSDW - bottled water100022
6M-4Y, MSDW - closed water source24611128491637
6M-4Y, MSDW - open water source126593070821
6M-4Y, PE - Yes6624713780
6M-4Y, PE - No307146511061700
5-19Y, MSDW - bottled water10009
5-19Y, MSDW - closed water source182411319767
5-19Y, MSDW - open water source111301039390
5-19Y, MSDW - missing00001
5-19Y, PE - Yes481344384
5-19Y, PE - No246581954782
5-19Y, PE - missing00001
20+Y, MSDW - bottled water10—012
20+Y, MSDW - closed water source8210—4943
20+Y, MSDW - open water source367—7485
20+Y, MSDW - missing00—01
20+Y, PE - Yes185—1397
20+Y, PE - No10112—101043
20+Y, PE - missing00—01
SecondaryNumber of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 2

The malaria prevention and risk factors characteristics were the following: Main source of drinking water (MSDW): bottled water, closed water source (piped water, tube well, dug well, protected well), open water source (unprotected well, spring water, rainwater, tanker truck, surface water); and Presence of electricity (PE): Yes, No. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 2
ParticipantsLow PD Group (Survey 2)Medium PD Group (Survey 2)High PD Group (Survey 2)Very High PD Group (Survey 2)Neg PD Group (Survey 2)
6M-4Y, MSDW - bottled water10004
6M-4Y, MSDW - closed water source2079344421784
6M-4Y, MSDW - open water source75552334835
6M-4Y, PE - Yes491899824
6M-4Y, PE - No23413058671799
5-19Y, MSDW - bottled water10003
5-19Y, MSDW - closed water source229452221760
5-19Y, MSDW - open water source10326715395
5-19Y, PE - Yes6012114366
5-19Y, PE - No273591832792
20+Y, MSDW - bottled water00004
20+Y, MSDW - closed water source87741987
20+Y, MSDW - open water source37316450
20+Y, PE - Yes23421436
20+Y, PE - No1016361005
SecondaryNumber of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 3

The malaria prevention and risk factors characteristics were the following: Main source of drinking water (MSDW): bottled water, closed water source (piped water, tube well, dug well, protected well), open water source (unprotected well, spring water, rainwater, tanker truck, surface water); and Presence of electricity (PE): Yes, No. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 3
ParticipantsLow PD Group (Survey 3)Medium PD Group (Survey 3)High PD Group (Survey 3)Very High PD Group (Survey 3)Neg PD Group (Survey 3)
6M-4Y, MSDW - bottled water000126
6M-4Y, MSDW - closed water source1859737531613
6M-4Y, MSDW - open water source94643737949
6M-4Y, PE - Yes3625811775
6M-4Y, PE - No24313666801813
5-19Y, MSDW - bottled water010013
5-19Y, MSDW - closed water source21451623715
5-19Y, MSDW - open water source12742712401
5-19Y, PE - Yes561957348
5-19Y, PE - No28575828781
20+Y, MSDW - bottled water000015
20+Y, MSDW - closed water source101821884
20+Y, MSDW - open water source70533503
20+Y, PE - Yes19301386
20+Y, PE - No15210531016
SecondaryNumber of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 4

The malaria prevention and risk factors characteristics were the following: Main source of drinking water (MSDW): bottled water, closed water source (piped water, tube well, dug well, protected well), open water source (unprotected well, spring water, rainwater, tanker truck, surface water); and Presence of electricity (PE): Yes, No. Data were collected across centers from subjects between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. Results were presented per the following P. falciparum parasite density status subgroups: Low, Medium, High, Very high, and Negative (Neg).

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects Classified by House Information Regarding Main Source of the Drinking Water and Presence of Electricity at Survey 4
ParticipantsLow PD Group (Survey 4)Medium PD Group (Survey 4)High PD Group (Survey 4)Very High PD Group (Survey 4)Neg PD Group (Survey 4)
6M-4Y, MSDW - bottled water00001
6M-4Y, MSDW - closed water source139791538656
6M-4Y, MSDW - open water source2924516191
6M-4Y, PE - Yes20503384
6M-4Y, PE - No148982051464
5-19Y, MSDW - bottled water00000
5-19Y, MSDW - closed water source15538129247
5-19Y, MSDW - open water source43134481
5-19Y, PE - Yes23834161
5-19Y, PE - No17543139167
20+Y, MSDW - bottled water00—01
20+Y, MSDW - closed water source692—1391
20+Y, MSDW - open water source182—0116
20+Y, PE - Yes92—0206
20+Y, PE - No782—1302
SecondaryNumber of Subjects With Malaria Prevention Measures (MPM) at Each Survey

The malaria prevention measures (MPM) data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for each Survey. The MPM results include the following categories: Use of Mosquito coils over 7 days (UMc \> 7D), Use of Insecticide spray over 7 days (UIs \> 7D), Use of Commercial Repellents over 7 days (UCR \> 7D), Use of Traditional Repellents over 7 days (UTR \> 7D), Use of none of above over 7 days (Una \>7D), Use of indoor residual spray in past 12 months to spray interior walls (Uirs past 12M), Use of indoor residual spray - number of months ago (Uirs-nM) or Use of indoor residual spray- no spray (Uirs-no spray): the number of months ago for each Uirs-nM sub-categories is defined using the following \[x Months\]. Not all Uirs-nM sub-categories were analyzed in each survey.

Time frame:
At each Survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Malaria Prevention Measures (MPM) at Each Survey
ParticipantsOverall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)
[6M-4Y], UMc > 7D, Yes433398348239
[6M-4Y], UMc > 7D, Missing/No276727992845954
[6M-4Y], UIs > 7D, Yes101604827
[6M-4Y], UIs > 7D, Missing/No3099313731451166
[6M-4Y], UCR > 7D, Yes452420
[6M-4Y], UCR > 7D, Missing/No3196319231691173
[6M-4Y], UTR > 7D, Yes7902
[6M-4Y], UTR > 7D, Missing/No3193318831931191
[6M-4Y], Una >7D, Yes266327262778905
[6M-4Y], Una >7D, Missing/No537471415288
[6M-4Y], Uirs past 12M, Yes591573
[6M-4Y], Uirs past 12M, Missing/No3141318231861190
[6M-4Y], Uirs-nM [1 Month]9110
[6M-4Y], Uirs-nM [11 Months]——1—
[6M-4Y], Uirs-nM [12 Months]512—
[6M-4Y], Uirs-nM [10 Months]———1
[6M-4Y], Uirs-nM [2 Months]63—1
[6M-4Y], Uirs-nM [3 Months]21531
[6M-4Y], Uirs-nM [4 Months]921—
[6M-4Y], Uirs-nM [5 Months]12——
[6M-4Y], Uirs-nM [6 Months]6———
[6M-4Y], Uirs-nM [7 Months]11——
[6M-4Y], Uirs-nM [9 Months]1———
[6M-4Y], Uirs-nM [no spray]3141318231861190
[5-19Y], UMc > 7D, Yes227209180127
[5-19Y], UMc > 7D, Missing/No138614181432479
[5-19Y], UIs > 7D, Yes45322010
[5-19Y], UIs > 7D, Missing/No156815951592596
[5-19Y], UCR > 7D, Yes42127
[5-19Y], UCR > 7D, Missing/No160916251600599
[5-19Y], UTR > 7D, Yes3302
[5-19Y], UTR > 7D, Missing/No161016241612604
[5-19Y], Una >7D, Yes133613811401460
[5-19Y], Una >7D, Missing/No277246211146
[5-19Y], Uirs past 12M, Yes24831
[5-19Y], Uirs past 12M, Missing/No158916191609605
[5-19Y], Uirs-nM [1 Month]21—1
[5-19Y], Uirs-nM [11 Months]——1—
[5-19Y], Uirs-nM [12 Months]211—
[5-19Y], Uirs-nM [2 Months]12—0
[5-19Y], Uirs-nM [3 Months]13300
[5-19Y], Uirs-nM [4 Months]201—
[5-19Y], Uirs-nM [5 Months]01——
[5-19Y], Uirs-nM [6 Months]4———
[5-19Y], Uirs-nM [7 Months]00——
[5-19Y], Uirs-nM [9 Months]0———
[5-19Y], Uirs-nM [no spray]158916191609605
[Y20+], UMc > 7D, Yes196199167117
[Y20+], UMc > 7D, Missing/No139213881428483
[Y20+], UIs > 7D, Yes46302811
[Y20+], UIs > 7D, Missing/No154215571567589
[Y20+], UCR > 7D, Yes041212
[Y20+], UCR > 7D, Missing/No158815831583588
[Y20+], UTR > 7D, Yes4400
[Y20+], UTR > 7D, Missing/No158415831595600
[Y20+], Una >7D, Yes134613501392460
[Y20+], Una >7D, Missing/No242237203140
[Y20+], Uirs past 12M, Yes32722
[Y20+], Uirs past 12M, Missing/No155615801593598
[Y20+], Uirs-nM [1 Month]70—0
[Y20+], Uirs-nM [11 Months]——0—
[Y20+], Uirs-nM [12 Months]301—
[Y20+], Uirs-nM [10 Months]———1
[Y20+], Uirs-nM [2 Months]41—1
[Y20+], Uirs-nM [3 Months]8310
[Y20+], Uirs-nM [4 Months]620—
[Y20+], Uirs-nM [5 Months]11——
[Y20+], Uirs-nM [6 Months]2———
[Y20+], Uirs-nM [7 Months]10——
[Y20+], Uirs-nM [9 Months]0———
[Y20+], Uirs-nM [no spray]155615801593598
SecondaryNumber of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 1

Data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 1. The other Plasmodium species assessed were: P. Malaria, P. Vivax, P. Ovale. Infection were determined using a blood smear slide, and categorized according positive (Pos) and negative (Neg) results.

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 1
ParticipantsOverall Study Group (6M-4Y) (Survey 1)Overall Study Group (5-19Y) (Survey 1)Overall Study Group (20Y+) (Survey 1)
P.Malariae, Pos19211
P.Malariae, Neg318115921587
P.Vivax, Pos000
P.Vivax, Neg320016131588
P.Ovale, Pos310
P.Ovale, Neg319716121588
SecondaryNumber of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 2

Data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 2. The other Plasmodium species assessed were: P. Malaria, P. Vivax, P. Ovale. Infection were determined using a blood smear slide, and categorized according positive (Pos) and negative (Neg) results.

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 2
ParticipantsOverall Study Group (6M-4Y) (Survey 2)Overall Study Group (5-19Y) (Survey 2)Overall Study Group (20Y+) (Survey 2)
P.Malariae, Pos32272
P.Malariae, Neg316516001585
P.Vivax, Pos000
P.Vivax, Neg319716271587
P.Ovale, Pos632
P.Ovale, Neg319116241585
SecondaryNumber of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 3

Data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 3. The other Plasmodium species assessed were: P. Malaria, P. Vivax, P. Ovale. Infection were determined using a blood smear slide, and categorized according positive (Pos) and negative (Neg) results.

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 3
ParticipantsOverall Study Group (6M-4Y) (Survey 3)Overall Study Group (5-19Y) (Survey 3)Overall Study Group (20Y+) (Survey 3)
P.Malariae, Pos48270
P.Malariae, Neg314515851595
P.Vivax, Pos000
P.Vivax, Neg319316121595
P.Ovale, Pos641
P.Ovale, Neg318716081594
SecondaryNumber of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 4

Data were collected across centers from subjects with age between and including: 6M-4Y, 5-19 Y and 20Y+, for Survey 4. The other Plasmodium species assessed were: P. Malaria, P. Vivax, P. Ovale. Infection were determined using a blood smear slide, and categorized according positive (Pos) and negative (Neg) results.

Time frame:
At Survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Plasmodium Species Other Than P. Falciparum at Survey 4
ParticipantsOverall Study Group (6M-4Y) (Survey 4)Overall Study Group (5-19Y) (Survey 4)Overall Study Group (20Y+) (Survey 4)
P.Malariae, Pos32280
P.Malariae, Neg1161578600
P.Vivax, Pos000
P.Vivax, Neg1193606600
P.Ovale, Pos331
P.Ovale, Neg1190603599
SecondaryNumber of Subjects With Serious Adverse Events (SAEs) Related to Study Procedure for Each Survey

Serious adverse events (SAEs) assessed include medical occurrences that result in death, are life threatening, require hospitalization or prolongation of hospitalization or result in disability/incapacity. Capillary blood sampling was the only invasive procedure involved in this study. SAEs related to this procedure were recorded at the Survey visit.

Time frame:
At each Survey visit
Reported as:
Count of participants · Participants
Number of Subjects With Serious Adverse Events (SAEs) Related to Study Procedure for Each Survey
ParticipantsOverall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)
Number of Subjects With Serious Adverse Events (SAEs) Related to Study Procedure for Each Survey0000

Adverse events

Collected over Capillary blood sampling was the only invasive procedure involved in this study. Serious adverse events (SAEs) related to this procedure were recorded at each survey visit.. Non-serious events are listed at a 5% frequency threshold.

Adverse event summary by group
GroupDeathsSeriousOther
Overall Study Group (Survey 1)0/6,404 (0%)0/6,404 (0%)—
Overall Study Group (Survey 2)0/6,414 (0%)0/6,414 (0%)—
Overall Study Group (Survey 3)0/6,400 (0%)0/6,400 (0%)—
Overall Study Group (Survey 4)0/2,400 (0%)0/2,400 (0%)—

Baseline characteristics

Age, Continuous
Age, Continuous(Years)Overall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)Total
Mean12.6 ± 14.612.1 ± 14.312.1 ± 14.212.4 ± 14.412.28 ± 14.37
Sex: Female, Male
Sex: Female, Male(Participants)Overall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)Total
Female367037913752142012633
Male2734262326489808985
Race and Ethnicity Not Collected
Race and Ethnicity Not Collected(Participants)Overall Study Group (Survey 1)Overall Study Group (Survey 2)Overall Study Group (Survey 3)Overall Study Group (Survey 4)Total
Count of participants————0
08

Study locations

8 sites
  • GSK Investigational Site
    Ouagadougou 01, Burkina Faso
  • GSK Investigational Site
    Lambaréné, Gabon
  • GSK Investigational Site
    Kintampo, Ghana
  • GSK Investigational Site
    Kumasi, Ghana
  • GSK Investigational Site
    Kisumu, Kenya
  • GSK Investigational Site
    Lilongwe, Malawi
  • GSK Investigational Site
    Dar-es-Salaam, Tanzania
  • GSK Investigational Site
    Korogwe, Tanga, Tanzania
09

References and documents

Publications

  • Drakeley C, Abdulla S, Agnandji ST, Fernandes JF, Kremsner P, Lell B, Mewono L, Bache BE, Mihayo MG, Juma O, Tanner M, Tahita MC, Tinto H, Diallo S, Lompo P, D'Alessandro U, Ogutu B, Otieno L, Otieno S, Otieno W, Oyieko J, Asante KP, Dery DB, Adjei G, Adeniji E, Atibilla D, Owusu-Agyei S, Greenwood B, Gesase S, Lusingu J, Mahende C, Mongi R, Segeja M, Adjei S, Agbenyega T, Agyekum A, Ansong D, Bawa JT, Boateng HO, Dandalo L, Escamilla V, Hoffman I, Maenje P, Martinson F, Carter T, Leboulleux D, Kaslow DC, Usuf E, Pircon JY, Bahmanyar ER. Longitudinal estimation of Plasmodium falciparum prevalence in relation to malaria prevention measures in six sub-Saharan African countries. Malar J. 2017 Oct 27;16(1):433. doi: 10.1186/s12936-017-2078-3. PubMed 29078773 ↗

Individual participant data

Plan to share: Yes — IPD for this study will be made available via the Clinical Study Data Request site.

Supporting information: Study protocol, Statistical analysis plan, Informed consent form, Clinical study report

Time frame: IPD is available via the Clinical Study Data Request site (click on the link provided below)

Access criteria: Access is provided after a research proposal is submitted and has received approval from the Independent Review Panel and after a Data Sharing Agreement is in place. Access is provided for an initial period of 12 months but an extension can be granted, when justified, for up to another 12 months.

Data sharing details ↗ · www.clinicalstudydatarequest.com

10

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Aug 18, 2020, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
11

Registry details

Key details

Study ID
NCT01190202
Lead sponsor
GlaxoSmithKline
Collaborators
The PATH Malaria Vaccine Initiative (MVI)
Responsible party
Sponsor
First posted
Aug 27, 2010
Start date
Mar 14, 2011
Primary completion
Dec 20, 2013
Completion
Dec 20, 2013
Results posted
Aug 18, 2020
Last update
Aug 18, 2020

Study contacts

GSK Clinical Trials
study director · GlaxoSmithKline
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Aug 2020. You cannot join it, but the record below documents what was studied.

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