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Lymphangioleiomyomatosis clinical trials

The registry lists 49 studies for Lymphangioleiomyomatosis across more than 10 countries. 11 are recruiting or about to start. 32 of them are mainly about Lymphangioleiomyomatosis (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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What changed in your saved searches, Oct 31 – Nov 6:

A study of drug A after surgery for early breast cancer

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Drug B with hormone therapy in advanced breast cancer

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· Sites: 4 added, including Seoul and Busan

· Enrollment: 300 → 450 participants

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Status

Completed
28
Recruiting
10
Status unknown
5
Terminated
3
Active, not recruiting
2
Enrolling by invitation
1

Phase

Phase 2
16
Phase 1
10
Phase 3
3
Phase 4
2
Early Phase 1
1

Where

United States
28
France
6
Italy
5
United Kingdom
3
Canada
3
China
3

Who runs them

National Heart, Lung, and Blood Institute (NHLBI) (8) · University of Cincinnati (5) · Brigham and Women's Hospital (3) · Novartis Pharmaceuticals (3) · Peking Union Medical College Hospital (2) · Children's Hospital Medical Center, Cincinnati (2) · Baylor College of Medicine (1) · Yonsei University (1)

What is being tested here

Drugs under test in Lymphangioleiomyomatosis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Imatinib102
Sirolimus026
Everolimus014
Carbon-11 acetate001
Letrozole001
Resveratrol001
Nintedanib001
Celecoxib001
Glutamine001
Simvastatin001

Drug classes tested here Tyrosine kinase inhibitors (TKIs) 1 open · mTOR inhibitors 11

Coming up

1phase 3 study under way
3studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 3

Who these studies take

Of the 10 Lymphangioleiomyomatosis studies recruiting now, 6 (60%) set no upper age limit and 1 (10%) stop at 75 or younger. 4 (40%) take children under 18. 6 (60%) are for women only and 0 (0%) for men only; 1 (10%) take healthy volunteers.

Recruiting studies that take each age, of 10
AgeWomenMen
103 (30%)1 (10%)
1810 (100%)4 (40%)
3010 (100%)4 (40%)
4010 (100%)4 (40%)
5010 (100%)4 (40%)
659 (90%)4 (40%)
759 (90%)4 (40%)
858 (80%)4 (40%)

Across all 49 studies, recruiting or not: 18% stop at 75 or younger and 16% at 65; 22% take children; 53% are for women only and 0% for men only; 6% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

What changed recently

From the registry's own updates since Oct 14, 2026.

Results posted1

Studies

Recruiting first, then most recently updated. Showing 49 of 49. search them.