Keratoconjunctivitis Sicca: all 797 studies

Page 2 of 8. Open to participants first (56), then studies with results posted, then the rest; newest registration first within each.

• 3-year Study in Dry Eye Disease Patients With Severe Keratitis Receiving Ikervis® (1mg/mL Ciclosporin)CompletedNCT04144413Phase 3Results posted
• Perfluorohexylcotane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Gobi Study)CompletedNCT04139798Phase 3Results posted
• Safety, PK and Efficacy Study of SJP-0132 in Subjects With Dry Eye DiseaseCompletedNCT04139122Phase 1/2Results posted
• Refitting Daily Disposable Contact Lens Wearers With Dry Eye Disease With A Different Daily Disposable Lens TypeCompletedNCT04105842Not applicableResults posted
• A Study Evaluating the Efficacy and Safety on Moderate to Severe Dry EyeCompletedNCT04092907Phase 2Results posted
• Comparison of Tear Evaporation Rate With Systane Complete in Dry Eye and Non-Dry EyeCompletedNCT04091581Phase 4Results posted
• A Study Assessing the Safety, Efficacy, and Optimum Dosage of K-161 in Subjects With Moderate to Severe Dry Eye DiseaseCompletedNCT04084483Phase 2Results posted
• Evaluation of the Efficacy and Safety of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye DiseaseCompletedNCT04036292Phase 3Results posted
• A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye DiseaseCompletedNCT04030962Phase 1/2Results posted
• Management of Signs and Symptoms Associated With Dry Eye DiseaseTerminatedNCT04015219Not applicableResults posted
• IVIG-eye Drops Treatment for Dry Eye DiseaseCompletedNCT03992482Phase 1/2Results posted
• A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry EyeCompletedNCT03982368Phase 2Results posted
• Tavilermide Ophthalmic Solution for the Treatment of Dry EyeCompletedNCT03925727Phase 3Results posted
• Evaluation of the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye DiseaseCompletedNCT03920215Phase 2/3Results posted
• A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Clinical Trial of Reproxalap to Assess the Safety and Efficacy in Subjects With Dry Eye DiseaseCompletedNCT03916042Phase 2Results posted
• Study to Evaluate the Safety and Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED)CompletedNCT03889886Phase 2Results posted
• The RENEW Trial: A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Adaptive Phase 3 Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye DiseaseCompletedNCT03879863Phase 3Results posted
• Efficacy of T2259 in DEDCompletedNCT03874429Not applicableResults posted
• Clinical Trial to Evaluate the Chronic Efficacy of OC-01 Nasal Spray on Signs of Dry Eye Disease (The MYSTIC Study)CompletedNCT03873246Phase 2Results posted
• A Study to Assess Efficacy and Safety of HL036 in Subjects With Dry EyesCompletedNCT03846453Phase 3Results posted
• Efficacy, Safety of T2769 in Dry Eye DiseaseCompletedNCT03830359Not applicableResults posted
• Goblet Cell Degranulation Produced by Intranasal Tear Neurostimulator (ITN) in Dry Eye DiseaseTerminatedNCT03827564Not applicableResults posted
• Study of Brimonidine Tartrate Nanoemulsion Eye Drop Solution in the Treatment of Dry Eye Disease (DED)CompletedNCT03785340Phase 3Results posted
• Study of SkQ1 as Treatment for Dry-eye SyndromeCompletedNCT03764735Phase 3Results posted
• TrueTear in Sjogren's Disease PatientsCompletedNCT03719885Not applicableResults posted
• Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic SubjectsCompletedNCT03660475Phase 2Results posted
• Intense Pulse Light Treatment With Meibomian Gland Expression of the Upper Eyelids in Dry Eye DiseaseCompletedNCT03658811Not applicableResults posted
• A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye Disease (DED)CompletedNCT03652051Phase 2Results posted
• Evaluation of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye DiseaseCompletedNCT03636061Phase 2Results posted
• Evaluation of the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (the RAINIER Study)CompletedNCT03633461Phase 2Results posted
• Safety and Efficacy of KPI-121 in Subjects With DEDCompletedNCT03616899Phase 3Results posted
• A Study to Evaluate AXR-159 Ophthalmic Solution in Patients With Dry Eye DiseaseCompletedNCT03598699Phase 2Results posted
• Ocular Tolerability of Voclosporin Ophthalmic Solution Versus Restasis® in Subjects With Dry Eye DiseaseCompletedNCT03597139Phase 2Results posted
• Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry EyeCompletedNCT03569202Not applicableResults posted
• Safety and Tolerability of the Ophthalmic Gel PRO-167 Versus Corneregel® on Healthy Subjects.CompletedNCT03520348Phase 1Results posted
• Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)CompletedNCT03452397Phase 2Results posted
• Dry Eye Disease Study With BrimonidineCompletedNCT03418727Phase 2Results posted
• Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry EyeCompletedNCT03417505Not applicableResults posted
• Effectiveness of Intense Pulsed Light for Improving Dry Eye SyndromeCompletedNCT03396913Not applicableResults posted
• A Study to Evaluate the Performance and Safety of CBL-102 Versus Vismed® Multi Eye Drops in the Management of Dry EyeCompletedNCT03368404Not applicableResults posted
• A Study to Assess Efficacy of HL036 in Subjects With Dry EyesCompletedNCT03334539Phase 2Results posted
• Perfluorohexyloctane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)CompletedNCT03333057Phase 2Results posted
• CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)CompletedNCT03292809Phase 2/3Results posted
• Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects With Dry Eye DiseaseCompletedNCT03287635Phase 4Results posted
• Optive Brand For Day And Night Dry Eye ManagementCompletedNCT03208673Not applicableResults posted
• Efficacy of IPL Treatment of Dry Eye and Ocular RosaceaCompletedNCT03194698Not applicableResults posted
• A Randomized, Double Masked, Clinical Study of Subjects With Dry Eye SyndromeCompletedNCT03162783Phase 2Results posted
• The Effects of Dietary Supplementation With Omega-3 Fatty Acids on Symptoms of Dry EyeCompletedNCT03141931Not applicableResults posted
• Dry Eye Symptom Relief Assessment With Use of TrueTear in a Controlled Adverse EnvironmentCompletedNCT03097614Not applicableResults posted
• Intense Pulsed Light Study for Dry Eye DiseaseCompletedNCT03089580Not applicableResults posted
• Safety and Efficacy of TOP1630 for Dry Eye SyndromeCompletedNCT03088605Phase 2Results posted
• An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry EyeCompletedNCT03019627Phase 2Results posted
• Symptom Response in Normal and Dry Eye Patients Secondary to Application of a Menthol-Containing Eyedrop (Rohto® Hydra)CompletedNCT02985827Phase 4Results posted
• Study of the Safety and Efficacy of OmegaD Softgels in the Treatment of Dry Eye DiseaseCompletedNCT02980224Phase 3Results posted
• A Study to Evaluate the Performance and Safety of CBL-101 Versus Vismed® Multi Eye Drops in the Management of Dry EyeCompletedNCT02975102Not applicableResults posted
• Tear Production by Nasal Neurostimulation Compared to Active ControlCompletedNCT02970799Not applicableResults posted
• Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry EyeTerminatedNCT02965846Phase 3Results posted
• Evaluation of Dry Eye Symptoms in CAE With Application of Intranasal NeurostimulationCompletedNCT02910713Not applicableResults posted
• A Two Comparator, Controlled Phase 3 Study in Patients With and Without Evaporative Dry EyeCompletedNCT02871440Phase 3Results posted
• Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens WearersCompletedNCT02848222Not applicableResults posted
• An Open-Label Extension of a Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis SiccaCompletedNCT02845674Phase 3Results posted
• Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye DiseaseTerminatedNCT02831387Phase 2Results posted
• Study of the Pharmacodynamic Activity of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye DiseaseTerminatedNCT02824913Phase 2Results posted
• Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye DiseaseCompletedNCT02819284Phase 3Results posted
• Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry EyeTerminatedNCT02815293Phase 3Results posted
• Safety and Efficacy of KPI-121 in Subjects With Dry Eye DiseaseCompletedNCT02813265Phase 3Results posted
• Acute Tear Production Following Single Use of the Oculeve Intranasal NeurostimulatorCompletedNCT02798289Not applicableResults posted
• Clinical Outcomes Following Treatment With SYSTANE® BALANCECompletedNCT02776670Not applicableResults posted
• Can Pregabalin Reduce the Frequency and Severity of Dry Eye Symptoms After Laser-assisted in Situ Keratomileusis?CompletedNCT02701764Phase 2/3Results posted
• Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis SiccaCompletedNCT02688556Phase 3Results posted
• A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye SyndromeCompletedNCT02680158Not applicableResults posted
• CyclASol for the Treatment of Moderate to Severe Dry-eye Disease (DED)CompletedNCT02617667Phase 2Results posted
• Clinical Effects and Safety of 3% Diquafosol After Cataract SurgeryCompletedNCT02608489Not applicableResults posted
• A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease.CompletedNCT02553772Phase 3Results posted
• Six Month Study to Evaluate the Safety and Effectiveness of the Intranasal Lacrimal NeurostimulatorCompletedNCT02526290Not applicableResults posted
• Clinical Evaluation of Systane® Balance in Dry Eye SubjectsTerminatedNCT02511379Not applicableResults posted
• Tolerability, Safety and Efficacy of Lubricin vs Sodium Hyaluronate Eye Drops in Subjects With Moderate Dry EyeCompletedNCT02510235Not applicableResults posted
• Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dry EyeCompletedNCT02507934Not applicableResults posted
• Evaluation of Clinical Outcomes After the Use of SYSTANE® HYDRATIONCompletedNCT02470429Not applicableResults posted
• OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry EyeCompletedNCT02468700Phase 2Results posted
• A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye ReliefCompletedNCT02455050Phase 3Results posted
• Clinical Evaluation Following Use of SYSTANE® ULTRA in the Management of Dry EyeCompletedNCT02446015Not applicableResults posted
• Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye DiseaseCompletedNCT02435914Phase 2Results posted
• Multicenter Trial Evaluating Quality of Tears Produced by Nasal NeurostimulationCompletedNCT02385292Not applicableResults posted
• Clinical Evaluation of Systane® Gel Drops in Dry Eye SubjectsCompletedNCT02380248Not applicableResults posted
• LME636 in the Relief of Persistent Ocular Discomfort in Subjects With Severe Dry Eye DiseaseCompletedNCT02365519Phase 2Results posted
• Evaluation of the Safety and Effectiveness of the Oculeve Intranasal Lacrimal Neurostimulator in Patients With Dry EyeCompletedNCT02313454Not applicableResults posted
• A Study to Evaluate Efficacy and Safety of Lifitegrast in Subjects With Dry Eye (OPUS-3)CompletedNCT02284516Phase 3Results posted
• A Safety and Efficacy Study of Refresh Optive® Gel Drops in Patients With Dry Eye DiseaseCompletedNCT02280473Phase 3Results posted
• Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry EyeCompletedNCT02257957Phase 3Results posted
• Phase 2/3 Dose-Ranging Study of the Safety and Efficacy of OTX-101 in the Treatment of Keratoconjunctivitis SiccaCompletedNCT02254265Phase 2/3Results posted
• Prevalence of Dry Eye Disease in Patients Diagnosed With Rheumatoid ArthritisCompletedNCT02252744Results posted
• The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular SurfaceTerminatedNCT02199964Not applicableResults posted
• DNase Treatment for Dry EyesTerminatedNCT02193490Phase 1/2Results posted
• Safety and Efficacy of KPI-121 in Subjects With Dry Eye DiseaseCompletedNCT02188160Phase 2Results posted
• Dry Eye Assessment and Management StudyCompletedNCT02128763Phase 3Results posted
• A Clinical Study to Assess the Safety and Efficacy of an Ophthalmic Solution (SkQ1) in the Treatment of Dry Eye Syndrome (DES)CompletedNCT02121301Phase 2Results posted
• The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DEDCompletedNCT02120079Phase 4Results posted
• A Safety and Efficacy Study of OPTIVE FUSION™ With VISMED® Multi for the Management of Dry EyeCompletedNCT02117687Phase 4Results posted
• Treatment of Meibomian Gland Dysfunction and Dry Eye in Contact Lens WearersCompletedNCT02102464Not applicableResults posted

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