Keratoconjunctivitis Sicca: all 797 studies

Page 1 of 8. Open to participants first (56), then studies with results posted, then the rest; newest registration first within each.

• A Dose Regimen Study of BRM421 Ophthalmic Solution in Patients With Dry Eye DiseaseNot yet recruitingNCT07078955Phase 2
• Impact of DED on the Accuracy of Preoperative Keratometry Values in the Calculation of IOL Power for Cataract Surgery.Not yet recruitingNCT06989827Not applicable
• Telemedicine Evaluation of Dry Eye Disease Using a Portable Automatic Ocular Surface Imaging Device (PAOSID)RecruitingNCT06984549
• Efficacy of Lipid-containing Artificial Tears in the Treatment of Dry EyeNot yet recruitingNCT06955585Not applicable
• A Study to Evaluate the Efficacy and Safety of Treatment With CsA-PG Ophthalmic Gel in Dry Eye PatientsNot yet recruitingNCT06942793Phase 3
• Phase III Clinical Study of Lifitegrast Ophthalmic Solution for the Treatment of Dry Eye DiseaseRecruitingNCT06879782Phase 3
• Efficacy of 0.28% Sodium Hyaluronate Eye Drops in Patient with Moderate to Severe Dry EyeEnrolling by invitationNCT06860659Phase 4
• Compare the Clinical Efficacy of 3% Diquafosol and 0.1% Hyaluronic Acid in Patients with Dry Eye After Trans-PRKNot yet recruitingNCT06852105Not applicable
• Role of Corneal Nerves in Dry Eye DiseaseRecruitingNCT06841471
• Efficacy of Platelet-Rich Plasma Injection in Dry Eye SyndromeRecruitingNCT06831253Not applicable
• The Effect of Cord Blood Serum Eyes Drops Administer in Patients With Severe Keratopathy Related to EGFR-I TreatmentRecruitingNCT06830551Not applicable
• Laser Acupuncture on Dry Eye and Sjögren's Syndrome-related Dry Eye Symptoms (LADESJS)RecruitingNCT06780293Phase 2
• Exosomes Proteomic for Sjogren's Syndrome and Dry Eye SyndromeRecruitingNCT06771427
• Impact of Cataract Surgery on the Incidence and Progression of Dry Eye DiseaseNot yet recruitingNCT06759168
• Transcutaneous Auricular Vagus Nerve Stimulation in Dry EyeRecruitingNCT06696625Not applicable
• Comparative Efficacy Study to Demonstrate the Non-inferiority of I-DROP® MGD Versus 2 Competitor Eye Drops in Managing Evaporative Dry EyeNot yet recruitingNCT06686368Phase 4
• Clinical Study Aimed At Evaluating the Safety and Efficacy of Tear Substitute Formulations in the Treatment of Dry Eye Disease.Not yet recruitingNCT06633471Early Phase 1
• Using Dry Eye As a Disease Model, Investigators Demonstrated the Optimal Selection of Individualized Clinical Interventions and the Superiority of Dynamic Treatment Discrimination in Chinese Medicine.Not yet recruitingNCT06605495Not applicable
• Limbal Stem Cell Derived Exosome (LSC-Exo) Eye Drop for Treatment of Dry EyeRecruitingNCT06543667Phase 1
• Effects of 3% Diquafosol on Tear Film and Vision-related Quality of Life in Orthokeratology Lens Related Dry EyeNot yet recruitingNCT06537349Not applicable
• iTear Single-center, Open-label, Single-arm StudyNot yet recruitingNCT06525961Phase 4
• Dryness Difference Between Before and After PhacoemulsificationRecruitingNCT06513000
• Exosome-miRNA and Transcriptome Profiling of Dry Eye Syndrome and Sjogren's SyndromeNot yet recruitingNCT06475027
• Evaluation of the Effectiveness of a Community Health Management Program for Dry Eye Disease in Middle-Aged and Elderly IndividualsRecruitingNCT06443554Not applicable
• Salivary Conductivity Screening for Dry Eye Disease and Sjögren's SyndromeRecruitingNCT06406933
• Cyclosporine and Intense Pulsed Light for Dry Eye in Contact Lens UsersRecruitingNCT06392438Phase 3
• Study to Evaluate the Safety and Tolerability of PRO-190 Ophthalmic Solution Compared to Systane Ultra® on the Ocular Surface.Not yet recruitingNCT06379685Phase 1
• Study to Evaluating PRO-240 Ophthalmic Solution Compared to Optive®Not yet recruitingNCT06375343Phase 1
• Assessment of Tear Production, Corneal Staining, and Comfort Level Wearing Different Types of Contact LensesNot yet recruitingNCT06351410Not applicable
• Evaluation of Dry Eye Disease's Signs in Patients Who Were Administered Intravitreal Anti-VEGF InjectionsRecruitingNCT06317922Not applicable
• The Pattern of Dry Eye Disease After Cataract SurgeryRecruitingNCT06298890
• A Study to Evaluate the Safety and Efficacy of VSJ-110 Compared to Placebo in the Treatment of Dry EyeRecruitingNCT06296966Phase 2
• Efficacy and Safety of AJU-S56 5% in Dry Eye Syndrome PatientsRecruitingNCT06291194Phase 3
• Neurological Dry Eye Study Stimulating Both Lacrimal and Vagus NervesNot yet recruitingNCT06271005Not applicable
• Dual-Polymer Hydroxypropyl Guar-and Hyaluronic Acid Lubricants in Rheumatoid ArthritisRecruitingNCT06209879Phase 4
• Safety and Efficacy of ST-100 (Vezocolmitide) Ophthalmic Solution 60 μg/ml Ophthalmic Solution in Subjects Diagnosed With Dry Eye Disease (DED)RecruitingNCT06178679Phase 3
• BroadBand Light for the Treatment of Dry Eye DiseaseNot yet recruitingNCT06174064Not applicable
• Observational Study on the Improvement of Dry Eye Syndrome, Treatment Satisfaction, and Intraocular Tolerance With Diquasol Eye DropsRecruitingNCT06172530
• Management of the Ocular Surface With Preservative-Free Lubricants in Patients With Dry EyeRecruitingNCT06162442
• Safety and Effectiveness of EyePeace on Signs and Symptoms of Dry Eye DiseaseNot yet recruitingNCT06158997Not applicable
• Effectiveness of Diquafosol Prophylactic Therapy to Prevent Dry Eye Disease for Cataract Surgery Patients in IndonesiaRecruitingNCT06146881Phase 2
• Study of Application of Pulse Electrical Stimulation Around Eye in Dry Eye Disease Patients Who Are Scheduled for Laser Epithelial Keratomileusis (LASEK) SurgeryRecruitingNCT06120348Not applicable
• The Effect of 0.05% CsA Eye Drops on Post-refractive Surgery Dry EyeRecruitingNCT06043908Phase 4
• Assess the Effects of Spectacles or Orthokeratology on Dry Eye Parameters in Children and Adolescents.Not yet recruitingNCT06023108Not applicable
• Clinical Trial to Determine the Efficacy and Safety of Insulin Eye Drops in Dry Eye in Patients with Topical HypotensorsRecruitingNCT06017362Phase 4
• Eye Mask on Sleep Quality and Tear Layer Function in Patients With Dry Eye DiseaseNot yet recruitingNCT06016166Not applicable
• Efficacy and Safety of USL for Dry Eye DiseaseNot yet recruitingNCT06016010Phase 2
• The Effects and Safety of Topical Spironolactone Ophthalmic Solution, 0.005 mg/cc in Subjects With Dry Eye DiseaseNot yet recruitingNCT05995392Early Phase 1
• The Effect of a Pre-cataract Surgical Ocular Hygiene Regime on Microbial Load, Tear Osmolarity, Dry Eye, and Inflammatory MarkersNot yet recruitingNCT05990712Phase 4
• Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry EyeRecruitingNCT05605314
• Efficacy and Safety of Topical Hydrocortisone on Signs and Symptoms of Dry Eye Associated to Meibomian Gland DysfunctionRecruitingNCT05159284Phase 4
• Causal Relationship Between Dry Eye and Accommodative SpasmRecruitingNCT05120401
• Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye DiseaseRecruitingNCT04673643Phase 2
• Ocular Microbiome and Immune System in Dry EyesRecruitingNCT04658238
• Dry Eye Syndrome, Healthy Control, Sjögren's Syndrome and Other Inflammation Disease in Taiwan BiobankNot yet recruitingNCT03938207
• Assessment of TFT by OCT in Healthy Subjects and Subjects With DESRecruitingNCT02585414
• A Study Evaluating the Safety of the Nasal PumpTerminatedNCT06329687Phase 4Results posted
• A Study to Assess the Safety and Efficacy of IC265 Ophthalmic Solution for Dry Eye in Adult ParticipantsTerminatedNCT05992922Phase 2Results posted
• Performance and Safety Assessment of T2769 in Contact Lens Wearers With Dry Eye Symptoms.CompletedNCT05931861Not applicableResults posted
• Phase 4 Study Evaluating the Safety of the Nasal Guide With TyrvayaCompletedNCT05918406Phase 4Results posted
• A Study to Assess Symptom Relief and Product Tolerability of ABBV-444 Drops in Adult ParticipantsCompletedNCT05878067Phase 3Results posted
• Nasal Spray Study in Sjogren's Dry Eye DiseaseCompletedNCT05700422Phase 4Results posted
• Study of INV-102 Ophthalmic Solution in Adults With Moderate Symptomatic Dry Eye DiseaseCompletedNCT05586152Phase 1/2Results posted
• Lifitegrast 5% for the Treatment of Dry Eye In Habitual Soft Contact Lens WearersCompletedNCT05505292Phase 4Results posted
• Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (ICECAP 1)CompletedNCT05467293Phase 2Results posted
• A Clinical Trial to Evaluate the Safety and Efficacy of Rreproxalap in Adults With Dry Eye DiseaseCompletedNCT05424549Phase 2Results posted
• A Study to Confirm the Efficacy and Safety of K-161 Ophthalmic Solution for Treatment of Moderate to Severe Dry Eye DiseaseCompletedNCT05403827Phase 3Results posted
• Study of SY-201 Ophthalmic Solution in Subjects With Dry Eye DiseaseCompletedNCT05370495Phase 1/2Results posted
• Safety Study of Tivanisiran to Treat Dry EyeCompletedNCT05310422Phase 3Results posted
• Study of ST-100 as Treatment for Dry Eye DiseaseCompletedNCT05241470Phase 2Results posted
• to Evaluate the Effectiveness and Safety of the Tixel® , VS LipiFlow® in the Treatment of Meibomian Gland DysfunctionCompletedNCT05162261Not applicableResults posted
• Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study)CompletedNCT05133180Phase 3Results posted
• A Study to Assess the Efficacy and Safety of Tanfanercept (HL036) Ophthalmic Solution in Participants With Dry EyeCompletedNCT05109702Phase 3Results posted
• Ocular Effects of Scleral Lens Wear on Dry Eye PatientsCompletedNCT05079321Not applicableResults posted
• The TRANQUILITY 2 Trial: A Phase 3 Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye DiseaseCompletedNCT05062330Phase 3Results posted
• A Clinical Trial to Assess Subjects With Dry Eye Disease.CompletedNCT04971031Phase 2Results posted
• Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland DisfunctionCompletedNCT04889950Not applicableResults posted
• To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye DiseaseCompletedNCT04747977Phase 2Results posted
• Research Study To See How Well An Eye Drop (SURF-200) Works, What Side Effects There Are, And To Compare It With Vehicle In Subjects With An Episodic Flare-Up of Dry Eye DiseaseCompletedNCT04734210Phase 2Results posted
• A Research Study To See How Well an Eye Drop, SURF-100 (A Mycophenolic Acid/Betamethasone Sodium Phosphate Combination), Works and What Side Effects There Are in Subjects With Dry Eye DiseaseCompletedNCT04734197Phase 2Results posted
• The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye DiseaseCompletedNCT04674358Phase 2/3Results posted
• Pilot Study to Investigate the Feasibility, Reliability and Efficacy of Utilizing OCT to Automate PROSE FittingCompletedNCT04649177Not applicableResults posted
• Effect of NOV03 on Signs and Symptoms of Dry Eye Disease Associated With Meibomian Gland Dysfunction (Mojave Study)CompletedNCT04567329Phase 3Results posted
• Study of VVN001 Ophthalmic Solution in Dry Eye DiseaseCompletedNCT04556838Phase 2Results posted
• Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or LotemaxCompletedNCT04555694Phase 4Results posted
• Study to Evaluate the Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS202)CompletedNCT04535947Phase 2Results posted
• CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease in Subjects Who Completed CYS-004CompletedNCT04523142Phase 3Results posted
• ESSENCE 2: CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)CompletedNCT04523129Phase 3Results posted
• Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry EyeTerminatedNCT04498468Phase 4Results posted
• A Phase 2b Study Evaluating the Safety and Efficacy of AR-15512 Ophthalmic Solution for the Treatment of Dry Eye DiseaseCompletedNCT04498182Phase 2Results posted
• Efficacy and Safety of a New Artificial Tear Formulation Compared With Systane Ultra Multidose in Participants With Dry Eye DiseaseCompletedNCT04393441Phase 3Results posted
• A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye DiseaseCompletedNCT04391894Phase 2Results posted
• Study to Evaluate the Safety, Tolerability, and Efficacy of OTX-CSI in Subjects With Dry Eye Disease.CompletedNCT04362670Phase 1/2Results posted
• Effect of Cequa™ in Subjects With Dry Eye DiseaseCompletedNCT04357795Phase 4Results posted
• Vehicle-Controlled Study of SkQ1 as Treatment for Dry-eye SyndromeCompletedNCT04206020Phase 3Results posted
• Phase 1/2a Safety and Efficacy of ALY688 Ophthalmic Solution in Subjects With Dry Eye DiseaseCompletedNCT04201574Phase 1/2Results posted
• Effect of Intraoperative Dexamethasone on Post-op Dry EyeCompletedNCT04184999Phase 4Results posted
• Phase 3 Study of the Safety and Efficacy of OmegaD Softgels in the Treatment of Dry Eye DiseaseCompletedNCT04181593Phase 3Results posted
• Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye DiseaseTerminatedNCT04159935Phase 4Results posted
• Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye SyndromeCompletedNCT04147650Phase 2/3Results posted

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