National Institute of Allergy and Infectious Diseases (NIAID): Herpes Simplex trials

The registry lists 21 Herpes Simplex studies with National Institute of Allergy and Infectious Diseases (NIAID) as lead sponsor. 3 are open to participants now and 5 have results posted.

Phase 1 4Phase 2 4Phase 3 5No phase 9(a study in two phases counts in both)

Studies

Open to participants first, then studies with results posted, then the rest; newest registration first within each.

• Natural History Study of GATA2 Deficiency and Related DisordersRecruitingNCT01905826
• The Natural History of Severe Viral Infections and Characterization of Immune Defects in Patients Without Known ImmunocompromiseRecruitingNCT01011712
• Genetic Studies of Chronic Active Epstein-Barr DiseaseRecruitingNCT00032513
• Neonatal Phase 1 Valacyclovir StudyCompletedNCT05468619Phase 1Results posted
• A Randomized Double-Blind Control-Comparison Crossover Trial of Oral Glutamine to Suppress Frequently Recurrent Herpes LabialisTerminatedNCT00913692Phase 2Results posted
• Long Term Treatment of Herpes Simplex Encephalitis (HSE) With ValacyclovirCompletedNCT00031486Phase 3Results posted
• Acyclovir for Herpes Infections Involving the Central Nervous System in NeonatesCompletedNCT00031460Phase 3Results posted
• Acyclovir Herpes Simplex Virus (HSV) Skin, Eye, and MouthCompletedNCT00031447Phase 3Results posted
• Trial Evaluating the Immunogenicity and Safety of an Adjuvanted Epstein-Barr Virus (EBV) Glycoprotein 350 Vaccine in EBV-seronegative PersonsCompletedNCT05683834Phase 1/2
• Interferon Responses in Eczema HerpeticumCompletedNCT01429311
• Effectiveness of Acyclovir in Suppressing HIV Viral Load in Women Coinfected With HIV and Herpes Simplex Virus Type 2 (HSV-2)CompletedNCT00371592Phase 2
• VivaGel™ in Healthy Young WomenCompletedNCT00331032Phase 1
• Herpevac Neonatal SubstudyTerminatedNCT00138320
• HIV and Genital Herpes Among High-Risk Men Who Have Sex With Men (MSM) in Lima, PeruCompletedNCT00023582
• Valaciclovir to Prevent Transmission of Herpes Simplex VirusCompletedNCT00001649Phase 3
• Structure of the Herpes Simplex Virus ReceptorCompletedNCT00001648
• The Effect of Acyclovir Treatment of the Herpes Simplex Virus (HSV) Infection on HIV Levels in the BloodCompletedNCT00001115Not applicable
• The Safety and Effectiveness of Valacyclovir HCl in the Treatment of Herpes Simplex or Varicella/Zoster Infections in HIV-1 Infected ChildrenWithdrawnNCT00001054Phase 1
• Comparison of Foscarnet Versus Vidarabine in the Treatment of Herpes Infection in Patients With AIDS Who Have Not Had Success With AcyclovirCompletedNCT00000985Phase 3
• The Tolerance of HIV-Infected Patients With Herpes Group Virus Infections to Oral Doses of FIAUCompletedNCT00000654Phase 2
• Treatment of Acyclovir-Resistant Mucocutaneous Herpes Simplex Disease in Patients With AIDS: Open Label Pilot Study of Topical TrifluridineCompletedNCT00000635Not applicable