Hepatic Encephalopathy: all 225 studies

Page 1 of 3. Open to participants first (53), then studies with results posted, then the rest; newest registration first within each.

• Effect of Mini-Program Monitoring on Hepatic Encephalopathy in Post-TIPS PatientsNot yet recruitingNCT07901556Not applicable
• Equivalence of Electronic vs Paper-based PHES in Diagnosing Hepatic EncephalopathyNot yet recruitingNCT07874204Not applicable
• Electronic PHES vs Paper-based PHES for Hepatic EncephalopathyNot yet recruitingNCT07852416Not applicable
• Daridorexant for Sleep Disturbance in Adults With Liver CirrhosisNot yet recruitingNCT07830303Phase 4
• Coil-Assisted Small-Diameter Covered-Stent Shunt Reduction for Refractory Hepatic Encephalopathy After TIPSRecruitingNCT07799948Not applicable
• Fecal Microbiota Transplantation for the Treatment of Refractory Hepatic Encephalopathy After TIPS SurgeryRecruitingNCT07683936Early Phase 1
• A Prospective Cohort Study on the Epidemiological Investigation, Diagnosis, and Treatment of Hepatic EncephalopathyNot yet recruitingNCT07612670
• Underdilated VCX-TIPS Versus EVL Plus NSBB for Secondary Prophylaxis of Variceal Bleeding in CirrhosisNot yet recruitingNCT07587671Not applicable
• 4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in CirrhosisRecruitingNCT07554183Not applicable
• Endoscopic Shunts Embolization for Refractory Hepatic EncephalopathyNot yet recruitingNCT07553858Not applicable
• Microbiota trAnSplant ThERaPy In hEpatiC Encephalopathy (MASTERPIECE)Not yet recruitingNCT07528690Phase 2
• Apixaban-PK Trial: Preventing Portal Hypertension Complications in CirrhosisRecruitingNCT07521332Phase 4
• Evaluation of the Outcome of Fecal Microbiota TransplantationNot yet recruitingNCT07454408Phase 1/2
• RENEW: Study of Porcine Liver Support in Participants With Acute-on-Chronic Liver FailureNot yet recruitingNCT07429838Phase 1/2
• The Liver Cirrhosis Cognitive Decline Scale (LiCCoS)RecruitingNCT07418008
• Underdilated-stent Technique Improves Post-TIPS EncephalopathyRecruitingNCT07349654Not applicable
• UDCA to Prevent Post-TIPS Hepatic EncephalopathyNot yet recruitingNCT07273734Not applicable
• Psychometric Hepatic Encephalopathy Score in Prediction of Minimal Hepatic Encephalopathy in Compensated Cirrhotic PatientsNot yet recruitingNCT07272707
• Comparison of Underdilated Versus Standard TIPS in Preventing Variceal Rebleeding in Patients With CirrhosisRecruitingNCT07253389Not applicable
• Pre-emptive RTO for An Early Detected Gastric Varices in CT/MR Angiogram TrialRecruitingNCT07168395Not applicable
• Study on Proteomic and Microbiome Changes in Patients With Hepatic Encephalopathy (HE)Not yet recruitingNCT07150195
• Mechanisms of Perioperative Systemic Inflammation in the Development of PND in Cirrhotic PatientsNot yet recruitingNCT07082946
• Affect of Melatonin on Sleep and Cognition in CirrhosisRecruitingNCT07046429Not applicable
• Correlation Between Serum Albumin Level and Severity of Hepatic Encephalopathy in Patients With Chronic Liver Disease in Sohag University HospitalRecruitingNCT06953921
• 7.0T Magnetic Resonance Imaging Study for Hepatic EncephalopathyNot yet recruitingNCT06923254
• A Study to Evaluate Role of Inhaled Amikacin to Prevent Ventilator Associated Pneumonia in Patients With CirrhosisRecruitingNCT06808074Phase 4
• Development of a Cognitive Tool for Rapid and Reliable Screening of Minimal Hepatic Encephalopathy: Pilot StudyRecruitingNCT06619106
• Small Diameter TIPS in Patients with Severe Liver Atrophy and Variceal BleedingNot yet recruitingNCT06589531Not applicable
• BCAA vs. Rifaximin in Patients With Cirrhosis for Secondary Prophylaxis of HERecruitingNCT06538077Phase 4
• Human Albumin Infusion in Liver Cirrhosis and Overt Hepatic Encephalopathy (HACHE)RecruitingNCT06483737Not applicable
• A PROspective Faecal MIcrobiota tranSplantation Trial to Improve outcomEs in Patients With CirrhosisRecruitingNCT06461208Phase 3
• Pilot Open-Label Trial of Resistant Potato Starch in Patients With Cirrhosis and Overt Hepatic EncephalopathyRecruitingNCT06425380Not applicable
• Prospective Cohort Study of Complications and Outcomes in CirrhosisRecruitingNCT06374511
• Utility of the Clamping Bean Test (CBT) for Covert Hepatic Encephalopathy ScreeningEnrolling by invitationNCT06367127
• Vegetarian Versus Non Vegetarian Based Diet in the Recurrence of Hepatic Encephalopathy in Patients With Cirrhosis: An Open Label Pilot StudyRecruitingNCT06328088
• Revealing Engagement Patterns Among Hepatic Encephalopathy PatientsNot yet recruitingNCT06201988
• Throid Dysfunction in Liver Failure and Its Eddects Upon OutcomeRecruitingNCT06179368
• Vegetable Proteins Versus Mixed Animal Proteins on the Outcome of Hepatic EncephalopathyNot yet recruitingNCT06075875Not applicable
• Efficacy of Lactoferrin as an Adjunct Therapy in Patients With Hepatic EncephalopathyNot yet recruitingNCT06072521Phase 2
• International Registry of Congenital Portosystemic Shunt (IRCPSS)Enrolling by invitationNCT06041906
• Microbiota, Sarcopenia, and Hepatic Encephalopathy Change in Cirrhotic Patients Before and After RehabilitationRecruitingNCT06040814Not applicable
• Efficacy of L-Ornithine L-Aspartate and Polyethylene Glycol in Cirrhotic Patients With Overt Hepatic EncephalopathyNot yet recruitingNCT05920213Phase 4
• The Efficacy and Safety of Rifaximin TreatmentRecruitingNCT05786859Early Phase 1
• Diagnosing Minimal Hepatic EncephalopathyEnrolling by invitationNCT05433948
• Immune Profile, Neuronal Dysfunction, Metabolomics and Ammonia in Therapeutic Response of HE in ACLFRecruitingNCT05421351
• Role of Sarcopenia and Nutritional/Physical Therapy Intervention in Post-TIPS Hepatic EncephalopathyRecruitingNCT05346029Not applicable
• Hepatic Encephalopathy Prevention With Polydextrose After TIPS: Pilot Study (POEME)RecruitingNCT05206487Not applicable
• Faecal Microbiota Transplantation for Liver CirrhosisRecruitingNCT04932577Phase 2/3
• Efficacy and Safety of Nitazoxanide in Preventing Recurrence of Hepatic EncephalopathyRecruitingNCT04161053Phase 3
• Late Evening and Early Morning Protein Supplement to Reduce Readmissions for Hepatic EncephalopathyRecruitingNCT04096014Not applicable
• Prevention of Post-TIPS Hepatic Encephalopathy by Administration of Rifaximin and LactuloseRecruitingNCT04073290Phase 4
• Safety and Efficacy of Fecal Microbiota TransplantationRecruitingNCT04014413Not applicable
• VICIS - Vienna Cirrhosis StudyRecruitingNCT03267615
• Implications of Fecal Microbiota Transplantation in Modulating the Effects of Liver CirrhosisCompletedNCT06478602Phase 3Results posted
• Evaluation of Rifaximin SSD for Delaying Encephalopathy Decompensation in Patients With CirrhosisCompletedNCT05297448Phase 3Results posted
• Deprescribing Proton Pump Inhibitors to Reduce Post-TIPS Hepatic EncephalopathyCompletedNCT05070351Phase 1/2Results posted
• A Trial to Improve Quality of Life in People With CirrhosisCompletedNCT05061992Phase 2/3Results posted
• VE303 for Treatment of Hepatic Encephalopathy (HE)CompletedNCT04899115Phase 2Results posted
• The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.CompletedNCT04675775Not applicableResults posted
• FMT in Cirrhosis and Hepatic EncephalopathyCompletedNCT03796598Phase 1/2Results posted
• MNK6106 for Liver Disease (Hepatic Cirrhosis) That in the Past Has Affected the Brain (Hepatic Encephalopathy)CompletedNCT03712280Phase 2Results posted
• Rifaximin Soluble Solid Dispersion (SSD) Tablets Plus Lactulose for the Treatment of Overt Hepatic Encephalopathy (OHE)CompletedNCT03515044Phase 2Results posted
• 13C-Methacetin Breath Test for the Prediction of Outcome in in ALI or ALFCompletedNCT02786836Phase 2/3Results posted
• A Retrospective, Open-label, Uncontrolled Cohort Study to Assess the Effectiveness and Safety of Lactulose Retention Enema in the Treatment of Cirrhotic Patients With Grade 3 or 4 (West Haven Criteria) Hepatic Encephalopathy (HE) [The RETRO Study]CompletedNCT02377947Results posted
• Effect of Rifaximine on Sleep Disorders in Patients Suffering From Hepatic EncephalopathyCompletedNCT02163837Not applicableResults posted
• Phase 2B Efficacy/Safety of Ornithine Phenylacetate in Hospitalized Cirrhotic Patients With Hepatic Encephalopathy (STOP-HE)CompletedNCT01966419Phase 2Results posted
• Efficacy, Safety, And Pharmacokinetics Of Rifaximin In Subjects With Severe Hepatic Impairment And Hepatic EncephalopathyTerminatedNCT01846663Phase 4Results posted
• The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic EncephalopathyCompletedNCT01842581Phase 4Results posted
• Effect of Intrathoracic Pressure Regulation on Traumatic Brain InjuryTerminatedNCT01824589Phase 4Results posted
• Efficacy Study of Polyethylene Glycol 3350-electrolyte Solution (GoLYTELY®) Versus Lactulose in Patients With Hepatic Encephalopathy.CompletedNCT01283152Not applicableResults posted
• A Study of Safety and Efficacy of HPN-100 in Subjects With Cirrhosis and Episodic Hepatic EncephalopathyCompletedNCT00999167Phase 2Results posted
• Manganese in Women With EncephalopathyTerminatedNCT00985010Results posted
• Safety and Tolerability Study of Rifaximin in Participants With a History of Hepatic EncephalopathyCompletedNCT00686920Phase 3Results posted
• Efficacy and Safety Study of Ammonul® in Patients With Grade 3 or 4 Hepatic EncephalopathyTerminatedNCT00597909Phase 2Results posted
• Rifaximin in Minimal Hepatic EncephalopathyCompletedNCT00533910Not applicableResults posted
• RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled TrialTerminatedNCT00364689Phase 3Results posted
• A 6-month Efficacy, Safety, and Tolerability Study of Rifaximin In Preventing Hepatic EncephalopathyCompletedNCT00298038Phase 3Results posted
• N-acetylcysteine in Non-Acetaminophen Pediatric Acute Liver FailureCompletedNCT00248625Phase 3Results posted
• Appropriate Management of Hepatic EncePhalopaThy AmonG cirrhOtic patieNts Admitted to Internal MedicineActive, not recruitingNCT07727070
• Efficacy and Safety of Lemborexant for Patients With Cirrhosis and Sleep ProblemsCompletedNCT07480096Phase 2
• Clinical Efficacy and Survival Prediction Analysis of Transjugular Intrahepatic Portosystemic Shunt in Patients With Liver CirrhosisActive, not recruitingNCT07437638
• A Study to See if an Investigational Medicine Called VS-01 Can Help and How Safe it is in the Treatment of Patients With Overt Hepatic EncephalopathyTerminatedNCT06987968Phase 2
• RTX001 Autologous Engineered Macrophages for Liver CirrhosisActive, not recruitingNCT06823713Phase 1/2
• Proton Pump Inhibitors in Cirrhotic PatientsCompletedNCT06384443
• Study in Patients With Decompensated Liver CirrhosisActive, not recruitingNCT06380335
• Fecal Microbiota Transplantation by Oral Capsules for Hepatic Encephalopathy TreatmentCompletedNCT06368895Phase 1
• Description of Lactulose Administration by Balloon Rectal Tube in Severe Hepatic EncephalopathyCompletedNCT06248736
• Metobolomics in the Characterisation of HECompletedNCT06245473
• Hepatic Encephalopathy and Albumin Lasting Cognitive ImprovementActive, not recruitingNCT06052176Phase 2
• Effectiveness of Oral Lactulose Versus Lactulose Enema in Hepatic EncephalopathyStatus unknownNCT05788627Phase 4
• Characterization of Metabolomic Fingerprints in Patients With Acute Liver Failure and Acute-on-chronic Liver Failure With Hepatic EncephalopathyWithdrawnNCT05772585
• Efficacy and Safety of Nifuroxazide in the Treatment of Hepatic Encephalopathy in Egyptian Patients With Liver CirrhosisCompletedNCT05754996Phase 3
• Intravenous BCAA for HE in ACLF (BCAA-HE-ACLF)CompletedNCT05700695Phase 1
• Explore the Efficacy and Safety of FMT With Different Bacterial Doses in the Treatment of Hepatic EncephalopathyActive, not recruitingNCT05669651Not applicable
• Role of Bilirubin Molecular Species in Hepatic Encephalopathy and Acute-on-chronic Liver FailureStatus unknownNCT05566548
• Efficacy of L-Ornithine L-Aspartate (LOLA) as an Adjunct to Branched Chain Amino Acids (BCAA) Enriched Solutions on Clinical Outcomes in ICU Patients With Hepatic EncephalopathyCompletedNCT05539027Phase 4
• Prevention of Hepatic Encephalopathy With Mobile Application Based Lactulose TitrationCompletedNCT05526404Not applicable
• Allopurinol Versus Atorvastatin to Prevent Complications of Liver CirrhosisCompletedNCT05511766Phase 2/3
• Prediction of Post-TIPS Hepatic Encephalopathy in Patients With Liver CirrhosisStatus unknownNCT05466669
• Speech in Hepatic Encephalopathy (HE)CompletedNCT05425316

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