Hemophilia A: all 885 studies

Page 3 of 9. Open to participants first (139), then studies with results posted, then the rest; newest registration first within each.

• A Trial Evaluating Efficacy and Safety of Prophylactic Administration of Concizumab in Patients With Severe Haemophilia A Without InhibitorsCompletedNCT03196297Phase 2Results posted
• A Trial Evaluating the Efficacy and Safety of Prophylactic Administration of Concizumab in Haemophilia A and B Patients With InhibitorsCompletedNCT03196284Phase 2Results posted
• A Study to Evaluate the Safety and Tolerability of Prophylactic Emicizumab in Hemophilia A Patients With InhibitorsCompletedNCT03191799Phase 3Results posted
• Dose-escalation Study to Investigate the Safety, PK, and PD of ISU304/CB2679d in Hemophilia B PatientsCompletedNCT03186677Phase 1Results posted
• ADYNOVATE Drug Use-Results SurveyCompletedNCT03169972Results posted
• Study of rFVIIIFc for Immune Tolerance Induction (ITI) in Haemophilia A Patients With Inhibitors Who Have Failed Previous ITI TherapiesCompletedNCT03103542Phase 4Results posted
• Alphanate in Immune Tolerance Induction TherapyTerminatedNCT03095287Phase 2Results posted
• A Study to Evaluate Efficacy of rFVIIIFc for Immune Tolerance Induction (ITI) in Severe Hemophilia A Participants With Inhibitors Undergoing the First ITI Treatment (verITI-8 Study)CompletedNCT03093480Phase 4Results posted
• Efficacy and Safety of AlphaNine Versus BeneFIX in Patients With Severe Hereditary Haemophilia BCompletedNCT03091751Phase 2Results posted
• A Study of Recombinant AAV2/6 Human Factor 8 Gene Therapy SB-525 (PF-07055480) in Subjects With Severe Hemophilia ACompletedNCT03061201Phase 2Results posted
• Post-Marketing Surveillance To Observe Safety And Efficacy Of Xyntha Solofuse Prefilled SyringeCompletedNCT03034044Results posted
• A Study to Evaluate the Efficacy, Safety, Pharmacokinetics, and Pharmacodynamics of Emicizumab Given Every 4 Weeks in Participants With Hemophilia ACompletedNCT03020160Phase 3Results posted
• A Gene Transfer Study for Hemophilia ACompletedNCT03003533Phase 1/2Results posted
• PF-06741086 Multiple Dose Study in Severe HemophiliaCompletedNCT02974855Phase 2Results posted
• Non-interventional Post-authorisation Study to Document the Immunogenicity, Safety, and Efficacy of NUWIQCompletedNCT02962765Results posted
• Clinical Study to Investigate the PK, Efficacy, and Safety of Wilate in Patients With Severe Hemophilia ACompletedNCT02954575Phase 3Results posted
• Efficacy and Safety of Turoctocog Alfa for Prophylaxis and Treatment of Bleeding Episodes in Previously Treated Chinese Patients With Haemophilia ACompletedNCT02938585Phase 3Results posted
• BAX 802 in CHA With InhibitorsTerminatedNCT02895945Phase 3Results posted
• A Clinical Trial to Evaluate Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants Without InhibitorsCompletedNCT02847637Phase 3Results posted
• A Study of Emicizumab Administered Subcutaneously (SC) in Pediatric Participants With Hemophilia A and Factor VIII (FVIII) InhibitorsCompletedNCT02795767Phase 3Results posted
• FEIBA Reconstitution Volume Reduction and Faster Infusion Study (FEIBA STAR)CompletedNCT02764489Phase 3Results posted
• Treatment Patterns And Outcomes In Patients Treated With Benefix Or Refacto/Refacto AF - A Swedish Cohort StudyCompletedNCT02740413Results posted
• BAX 826 Dose-Escalation Safety StudyCompletedNCT02716194Phase 1Results posted
• Ascending Dose Study of Genome Editing by Zinc Finger Nuclease Therapeutic SB-FIX in Subjects With Severe Hemophilia BTerminatedNCT02695160Phase 1Results posted
• A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Prophylactic Emicizumab Versus no Prophylaxis in Hemophilia A Participants With InhibitorsCompletedNCT02622321Phase 3Results posted
• Safety and Dose Finding Study of DTX101 (AAVrh10FIX) in Adults With Moderate/Severe to Severe Hemophilia BTerminatedNCT02618915Phase 1/2Results posted
• A Study of PEGylated Recombinant Factor VIII (BAX855) in Previously Untreated Young Children With Severe Hemophilia ACompletedNCT02615691Phase 3Results posted
• Platelet-Rich Plasma Intra-Articular Injection in Treating Hemophilic ArthropathyCompletedNCT02601170Not applicableResults posted
• Weight-based Dosing in Hemophilia ATerminatedNCT02586012Phase 2Results posted
• BAX 855 PK-guided DosingCompletedNCT02585960Phase 3Results posted
• Gene Therapy Study in Severe Haemophilia A Patients (270-201)CompletedNCT02576795Phase 1/2Results posted
• An Open-label Extension Study of an Investigational Drug, Fitusiran, in Patients With Moderate or Severe Hemophilia A or BCompletedNCT02554773Phase 1/2Results posted
• LR769 in Congenital Hemophilia Patients With Inhibitors Undergoing Elective Surgery or Invasive ProceduresCompletedNCT02548143Phase 3Results posted
• Pharmacogenetic Testing of Saliva Samples From Patients With Five or More Exposure Days to rFVIIa Analogue in the Adept™2 TrialCompletedNCT02541942Phase 2Results posted
• Pharmacokinetics and Safety of rFVIIIFc Manufactured at 15,000 L (15K) ScaleCompletedNCT02502149Phase 3Results posted
• PF-05208756, Moroctocog Alfa (AF-CC), Xyntha For Hemophilia ACompletedNCT02492984Phase 4Results posted
• A Gene Therapy Study for Hemophilia BCompletedNCT02484092Phase 2Results posted
• Study of PF-05208756, Moroctocog Alfa (AF-CC), Xyntha For Male Chinese Subjects With Hemophilia ACompletedNCT02461992Phase 1Results posted
• A Phase III Study on the Safety, Pharmacokinetics and Efficacy of Coagulation Factor VIIaCompletedNCT02448680Phase 3Results posted
• Trial of AAV5-hFIX in Severe or Moderately Severe Hemophilia BCompletedNCT02396342Phase 1/2Results posted
• Safety and Efficacy of Benefix in Patients With Hemophilia B in Usual Care Settings in ChinaCompletedNCT02336178Phase 4Results posted
• Prospective Biomarkers of Bone Metabolism in Hemophilia ACompletedNCT02306694Phase 3Results posted
• Assess the Efficacy and Safety of Personalized Prophylaxis Human-cl rhFVIII in Patients With Severe Haemophilia ACompletedNCT02256917Phase 3Results posted
• An Open Label Study to Determine the Safety and Efficacy of Replacement Factor VIII Protein (Known as rFVIIIFc) in Previously Untreated Males With Severe Hemophilia ACompletedNCT02234323Phase 3Results posted
• Study to Determine the Safety and Efficacy of rFIXFc in Previously Untreated Males With Severe Hemophilia BCompletedNCT02234310Phase 3Results posted
• An Open-Label, Single Dose Pharmacokinetic Study of Benefix (Recombinant Factor IX) in Male Chinese Subjects With Hemophilia BCompletedNCT02213250Phase 1Results posted
• BAX 855 Pediatric StudyCompletedNCT02210091Phase 3Results posted
• An Institutional Pilot Study to Investigate Physical Activity Patterns in Boys With HemophiliaCompletedNCT02199717Results posted
• Multidisciplinary Evaluation of Patients With HemophiliaCompletedNCT02198430Results posted
• Physiotherapy in the Haemophilic Arthropathy of the Elbow.CompletedNCT02198040Not applicableResults posted
• An Open-label Safety and Efficacy Study of Recombinant FVIII in Patients With Severe Hemophilia ACompletedNCT02172950Phase 3Results posted
• Bilateral Deficit Phenomenon in Patients With Haemophilic ArthropathyCompletedNCT02165462Results posted
• Safety and Efficacy of Turoctocog Alfa Pegol (N8-GP) in Previously Untreated Patients With Haemophilia ACompletedNCT02137850Phase 3Results posted
• Pharmacokinetic, Efficacy, and Safety Study of Recombinant Factor VIII Single Chain (rVIII-SingleChain) in Children With Severe Hemophilia ACompletedNCT02093897Phase 3Results posted
• Pharmacokinetics of rFVIIIFc at Two Vial StrengthsCompletedNCT02083965Phase 1Results posted
• A Safety and Efficacy Extension Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia BCompletedNCT02053792Phase 3Results posted
• Phase III Study of Coagulation FVIIa (Recombinant) in Congenital Hemophilia A or B Patients With InhibitorsCompletedNCT02020369Phase 3Results posted
• Study to Investigate Immunogenicity, Efficacy and Safety of Treatment With Human-cl rhFVIIICompletedNCT01992549Phase 3Results posted
• Evaluation Of Acceptability And Satisfaction Of Hemophilia Patients Treated With FusENGOCompletedNCT01959919Results posted
• BAX 855 ContinuationCompletedNCT01945593Phase 3Results posted
• Phase 3 Efficacy and Safety Study of BAX 855 in Severe Hemophilia A Patients Undergoing Surgical ProceduresCompletedNCT01913405Phase 3Results posted
• Assess the Safety and Efficacy of Individually Tailored Prophylaxis With Human-cl rhFVIII in Patients With Severe Haemophilia ACompletedNCT01863758Phase 3Results posted
• Post-Marketing Safety Study Following Long-Term Prophylactic OptivateTreatment in Subjects With Severe Haemophilia ATerminatedNCT01811875Phase 4Results posted
• Prophylaxis Versus on Demand Treatment for Children With Hemophilia ACompletedNCT01810666Phase 4Results posted
• Post Marketing Surveillance To Observe Safety And Efficacy Of Xyntha® In Subjects With Hemophilia ACompletedNCT01790828Results posted
• Recombinant Factor VIIa BI (rFVIIa BI) Treatment of Acute Bleeding Episodes Per an On-demand RegimenCompletedNCT01757405Phase 3Results posted
• Study Investigating a PEGylated Recombinant Factor VIII (BAX 855) for Hemophilia A (PROLONG-ATE Study)CompletedNCT01736475Phase 2/3Results posted
• A Multinational, Open-Label, Non-Controlled Trial on Safety, Efficacy and Pharmacokinetics of NNC 0129-0000-1003 in Previously Treated Paediatric Patients With Severe Haemophilia ACompletedNCT01731600Phase 3Results posted
• Human Cell Line-derived Recombinant Factor VIII (Human-cl-rhFVIII) in Previously Untreated PatientsCompletedNCT01712438Phase 3Results posted
• Viral Kinetics in HCV Clearance in Subjects With HemophiliaCompletedNCT01704521Phase 1Results posted
• A Safety, Efficacy and Pharmacokinetics Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Children With Hemophilia BCompletedNCT01662531Phase 3Results posted
• A Trial Investigating Safety and Efficacy of Treatment With BAY94-9027 in Severe Hemophilia ACompletedNCT01580293Phase 2/3Results posted
• BAX 326 Surgery Study in Hemophilia B PatientsCompletedNCT01507896Phase 3Results posted
• A Safety and Efficacy Study of a Recombinant Fusion Protein Linking Coagulation Factor IX With Albumin (rIX-FP) in Patients With Hemophilia BCompletedNCT01496274Phase 2/3Results posted
• Safety and Efficacy of Turoctocog Alfa in Prevention and Treatment of Bleeds in Previously Untreated Children With Haemophilia ACompletedNCT01493778Phase 3Results posted
• Evaluating the Haemostatic Effect of NNC 0129-0000-1003 During Surgical Procedures in Subjects With Haemophilia A.CompletedNCT01489111Phase 3Results posted
• BAX 326 Pediatric StudyCompletedNCT01488994Phase 2/3Results posted
• An Open-label Safety, Efficacy and Pharmacokinetic Study of a Recombinant FVIII Compared to Recombinant Human Antihemophilic FVIII in Patients With Severe Hemophilia ACompletedNCT01486927Phase 2/3Results posted
• Evaluation of Safety and Efficacy, Including Pharmacokinetics, of NNC 0129-0000-1003 When Administered for Treatment and Prophylaxis of Bleeding in Subjects With Haemophilia ACompletedNCT01480180Phase 3Results posted
• Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of Recombinant Coagulation Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Pediatric Subjects With Hemophilia ACompletedNCT01458106Phase 3Results posted
• Long-Term Safety and Efficacy of rFVIIIFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia ACompletedNCT01454739Phase 3Results posted
• Study of Recombinant Coagulation Factor IX Fc Fusion Protein, BIIB029, in Previously Treated Pediatric Participants With Hemophilia BCompletedNCT01440946Phase 3Results posted
• Phase 1 Safety, Pharmacokinetics And Pharmacodynamics Study Of Recombinant Factor VIIa Variant (813d) In Adult Subjects With HemophiliaCompletedNCT01439971Phase 1Results posted
• Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Congenital Hemophilia ATerminatedNCT01434511Phase 3Results posted
• Long-Term Safety and Efficacy of rFIXFc in the Prevention and Treatment of Bleeding Episodes in Previously Treated Participants With Hemophilia BCompletedNCT01425723Phase 3Results posted
• Hemophilia Adult Prophylaxis Study: Factor VIII in Severe Hemophilia ATerminatedNCT01405742Phase 3Results posted
• Safety and Efficacy of NNC-0156-0000-0009 After Long-Term Exposure in Patients With Haemophilia B: An Extension to Trials NN7999-3747 and NN7999-3773CompletedNCT01395810Phase 3Results posted
• Efficacy and Safety of NNC 0078-0000-0007 in Patients With Congenital Haemophilia and InhibitorsCompletedNCT01392547Phase 3Results posted
• Efficacy and Safety of NNC-0156-0000-0009 During Surgical Procedures in Subjects With Haemophilia BCompletedNCT01386528Phase 3Results posted
• Early Prophylaxis Immunologic Challenge (EPIC) StudyTerminatedNCT01376700Phase 3Results posted
• A Safety and Efficacy Study of a Recombinant Factor IX in Patients With Severe Hemophilia BCompletedNCT01361126Phase 1/2Results posted
• Study to Investigate the Long-term Efficacy and Safety of Human-cl rhFVIII in Previously Treated Patients (PTPs)CompletedNCT01341912Phase 3Results posted
• Study To Compare On-Demand Treatment To A Prophylaxis Regimen Of BeneFIX In Subjects With Moderately Severe to Severe Hemophilia BCompletedNCT01335061Phase 3Results posted
• Safety and Efficacy of NNC-0156-0000-0009 in Haemophilia B PatientsCompletedNCT01333111Phase 3Results posted
• BAY81-8973 Pediatric Safety and Efficacy TrialCompletedNCT01311648Phase 3Results posted
• BAX 326 (rFIX) Continuation StudyCompletedNCT01286779Phase 3Results posted
• Study of Recombinant Factor IX Product, IB1001, in Previously Treated Pediatric Subjects With Hemophilia BTerminatedNCT01271868Phase 3Results posted
• A Trial to Compare Prophylaxis Therapy to On-demand Therapy With a New Full Length Recombinant FVIII in Patients With Severe Hemophilia ACompletedNCT01233258Phase 3Results posted
• Study to Evaluate the Safety, Pharmacokinetics and Efficacy of Recombinant Factor VIII Fc Fusion Protein (rFVIIIFc) in Previously Treated Subjects With Severe Hemophilia ACompletedNCT01181128Phase 3Results posted
• Study of Modified Recombinant Factor VIII (OBI-1) in Subjects With Acquired Hemophilia ACompletedNCT01178294Phase 2/3Results posted

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