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Hemophilia A clinical trials

The registry lists 844 studies for Hemophilia A across more than 10 countries. 136 are recruiting or about to start. 779 of them are mainly about Hemophilia A (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

ClinicalTrials.gov finds 945 studies for Hemophilia A. How that becomes 843 here

This page counts the studies the registry files under Hemophilia A, and those it files under no condition that list Hemophilia Athemselves. Each study its search finds is placed by how the registry filed it and by the conditions it lists. ClinicalTrials.gov counts as of Nov 8, 2026. How condition pages count

  1. 945Found by its condition searchIt reads the conditions a study lists and their synonyms, and also titles and keywords.
  2. −75List Hemophilia A as a condition, but the registry did not file them under itMost often written as “Hemophilia B” (45), “Haemophilia B” (11), and “Acquired Hemophilia A” (10). The registry filed them under other conditions only, most often Hemophilia B (57) and Factor 8 deficiency, acquired (11).
  3. −32Match it another way7 name it in the title, 1 in a keyword, and 24 by a synonym or other text the search reads.
  4. 838Counted here and found by its search49 of them list Hemophilia A in their own words; the registry filed them under no condition.
  5. +5
    Counted here, but its search does not find them
  6. 843The count on this page

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Status

Completed
501
Recruiting
86
Status unknown
81
Terminated
60
Active, not recruiting
43
Not yet recruiting
38

Phase

Phase 3
169
Phase 1
102
Phase 2
80
Phase 4
77
Early Phase 1
7

Where

United States
299
Spain
180
France
157
United Kingdom
155
Italy
151
Germany
142

Who runs them

Novo Nordisk A/S (92) · Bayer (57) · Baxalta now part of Shire (40) · Pfizer (35) · Investigación en Hemofilia y Fisioterapia (21) · Hoffmann-La Roche (17) · Swedish Orphan Biovitrum (15) · Octapharma (15)

What is being tested here

Drugs under test in Hemophilia A studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Emicizumab51321
Marstacimab449
NXT007434
SR604313
Fitusiran2710
KN057213
Simoctocog alfa (Nuwiq)213
Antihemophilic factor, human recombinant1721
Recombinant FVIIa1313
Efanesoctocog alfa1511

Coming up

36phase 3 studies under way
48studies finish main data collection within a year10 of them phase 3

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

The 10 nearest, phase 3 first

Who these studies take

Of the 86 Hemophilia A studies recruiting now, 51 (59%) set no upper age limit and 30 (35%) stop at 75 or younger. 54 (63%) take children under 18. 2 (2%) are for women only and 42 (49%) for men only; 10 (12%) take healthy volunteers.

Recruiting studies that take each age, of 86
AgeWomenMen
1023 (27%)36 (42%)
1842 (49%)77 (90%)
3039 (45%)75 (87%)
4039 (45%)74 (86%)
5039 (45%)72 (84%)
6538 (44%)67 (78%)
7534 (40%)55 (64%)
8534 (40%)52 (60%)

Across all 844 studies, recruiting or not: 47% stop at 75 or younger and 41% at 65; 66% take children; 2% are for women only and 60% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Hemophilia A studies take

Of 91 phase 3 interventional studies under Hemophilia A, half reached primary completion within 33 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Phase 113 mo7–26 · 46 studies10 mo5–18 · 37 studies—
Phase 1/276 mo21–94 · 20 studies——
Phase 213 mo8–20 · 18 studies——
Phase 333 mo20–56 · 91 studies32 mo18–56 · 89 studies—
Phase 431 mo13–112 · 39 studies——
Interventional, no phase11 mo5–38 · 75 studies—11 mo5–38 · 72 studies
Observational45 mo25–79 · 131 studies58 mo34–79 · 53 studies36 mo15–96 · 78 studies

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 14, 2026.

Started recruiting2

Stopped1

Newly registered4

Studies

Recruiting first, then most recently updated. Showing 50 of 844. Browse all 844 → or search them.