Hemolysis clinical trials
The registry lists 120 studies for Hemolysis across more than 10 countries. 22 are recruiting or about to start. 45 of them are mainly about Hemolysis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-22.
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Who runs them
Alexion Pharmaceuticals, Inc. (6) · National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) (5) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Hospices Civils de Lyon (3) · Assistance Publique - Hôpitaux de Paris (3) · Novartis Pharmaceuticals (3) · Apellis Pharmaceuticals, Inc. (3) · Cairo University (2)
What is being tested here
Drugs under test in Hemolysis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 3, phase 3 first
- May 2027Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular Hemolysis · Phase 3 · Alexion Pharmaceuticals, Inc.
- Nov 2026Pneumatic Tube System Versus Personnel Transport and the Hemolysis Index of Emergency Department Blood Samples: A Randomized, Split-Sample, Single-Blind Trial · Marmara University Pendik Training and Research Hospital
- Dec 2026Modeling Blood Management and Hemolytic Risk in Pediatric Heart Surgery · Boston Children's Hospital
Who these studies take
Of the 19 Hemolysis studies recruiting now, 6 (32%) set no upper age limit and 9 (47%) stop at 75 or younger. 6 (32%) take children under 18. 3 (16%) are for women only and 0 (0%) for men only; 1 (5%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 3 (16%) | 3 (16%) |
| 18 | 12 (63%) | 10 (53%) |
| 30 | 12 (63%) | 10 (53%) |
| 40 | 14 (74%) | 11 (58%) |
| 50 | 12 (63%) | 11 (58%) |
| 65 | 12 (63%) | 12 (63%) |
| 75 | 10 (53%) | 10 (53%) |
| 85 | 10 (53%) | 10 (53%) |
Across all 120 studies, recruiting or not: 30% stop at 75 or younger and 25% at 65; 36% take children; 3% are for women only and 2% for men only; 16% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Hemolysis studies take
Of 28 interventional studies with no phase under Hemolysis, half reached primary completion within 11 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Interventional, no phase | 11 mo3–35 · 28 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 120. Browse all 120 → or search them.
- Ravulizumab in Pregnancies Complicated by Severe Hypertensive DisordersRecruitingNCT06333652Phase 21 country
- Pneumatic Tube System Versus Personnel Transport and the Hemolysis Index of Emergency Department Blood Samples: A Randomized, Split-Sample, Single-Blind TrialRecruitingNCT07755007Not applicable1 country
- Wise Practice of Chinese Hemodialysis (WISHES)RecruitingNCT030019211 country
- A Natural History Study Seeks to Understand the Clinical, Genomic, Pharmacological, Laboratory, and Dietary Determinates of Pyrimidine and Purine Metabolism DisordersRecruitingNCT060923461 country
- A Study of Iptacopan in Korean Patients With Paroxysmal Nocturnal Hemoglobinuria or C3 GlomerulopathyRecruitingNCT074161621 country
- Danicopan Early Access ProgramAvailableNCT059829381 country
- Comparison of Efficacy and Safety of Manual Syringing Versus Pneumatic Pressure Bag for Blood Transfusion in Patients Undergoing Cesarean Section With Major Obstetric HemorrhageRecruitingNCT07466719Not applicable1 country
- Feasibility Performance Study of ABL90 FLEX PLUS HEMRecruitingNCT073450911 country
- Modeling Blood Management and Hemolytic Risk in Pediatric Heart SurgeryRecruitingNCT067214551 country
- Study of Danicopan as Add-on Treatment to Ravulizumab or Eculizumab in Pediatric Participants With PNH Who Have Clinically Significant Extravascular HemolysisRecruitingNCT06449001Phase 33 countries
- Optimizing Pulsatility During Cardiopulmonary Bypass to Reduce Acute Kidney InjuryRecruitingNCT06349577Not applicable1 country
- Ventilatory Functions and Physical Intolerance in ESRD Adolescents: Response to Program of Walking With DogsRecruitingNCT06861816Not applicable1 country
- Restless Leg Syndrome: Is There a Response to Buddhist Walking Meditation in HemodialysisRecruitingNCT06806891Not applicable1 country
- Relationship Between Biological Phenotype, Clinical Severity of Sickle Cell Disease, and Blood CoagulationNot yet recruitingNCT066190931 country
- Safe Threshold to Discontinue Phototherapy in Hemolytic Disease of NewbornRecruitingNCT04218318Not applicable1 country
- Post-market Clinical Monitoring of the Safety and Efficacy of the Aortic Valve BioprothesisRecruitingNCT059986941 country
- Renal Function and Hemolysis After Pulsed-field Ablation for Atrial FibrillationRecruitingNCT061989331 country
- Biodex Training in Hemodialysis Females With OsteopeniaRecruitingNCT06223802Not applicable1 country
- RADeep Multicenter European Epidemiological Platform for Patients Diagnosed With Rare Anemia Disorders (RADs)RecruitingNCT062134021 country
- Hemolysis During Pulsed-field and Radiofrequency AblationNot yet recruitingNCT060964281 country
- Hemolysis Related Complications in SCD. A Phase II Study With VoxelotorRecruitingNCT05199766Phase 21 country
- A Study on the Safety, Tolerability, Efficacy, Pharmacokinetics and Pharmacodynamics of CAN106 in Subjects With PNHRecruitingNCT05539248Phase 1/21 country
- Early vs. Late Tourniquet Release and Phlebotomy-Induced Hemolysis in the Emergency Department: TOURNI-EDCompletedNCT07617103Not applicable1 country
- A Long-term Safety and Efficacy Study of Danicopan as an Add-on Therapy to Complement Component 5 Inhibitor (C5i) in Participants With PNHActive, not recruitingNCT05389449Phase 315 countries
- Therapeutic Orientation Test in Thrombotic MicroangiopathyCompletedNCT04777435Not applicable1 country
- A Study of Etavopivat in Adults and Adolescents With Sickle Cell Disease (HIBISCUS)Active, not recruitingNCT04624659Phase 317 countries
- A Study of Etavopivat in Patients With Thalassemia or Sickle Cell DiseaseCompletedNCT04987489Phase 26 countries
- Effects of Nitric Oxide on the Endothelium During Hemolysis.WithdrawnNCT03748082Phase 21 country
- Hereditary Spherocytosis and Vascular FunctionCompletedNCT04451785Not applicable1 country
- HEMolysis in a Percutaneous Axial Flow LVAD, Effects of Pentoxifylline in a Randomized Controlled TrialWithdrawnNCT04391231Phase 41 country
- Danicopan as Add-on Therapy to a C5 Inhibitor in Paroxysmal Nocturnal Hemoglobinuria (PNH) Participants Who Have Clinically Evident Extravascular Hemolysis (EVH)(ALPHA)CompletedNCT04469465Phase 318 countries
- CPB Prime Fluid Strategies to Preserve Mcirocirculatory PerfusionCompletedNCT05647057Not applicable1 country
- Primaquine Enantiomers in G6PD Deficient Human VolunteersCompletedNCT04073953Phase 11 country
- Study of the Oral Factor D (FD) Inhibitor ALXN2050 in PNH Patients as MonotherapyTerminatedNCT04170023Phase 27 countries
- Electric Polarization of Red Blood Cells : A Cohort Study to Assess the Erythrocytes Membrane Integrity Through Charge Conservation, Following Cardiac Surgery.WithdrawnNCT057542941 country
- Sildenafil To Prevent ClotCompletedNCT03199612Early Phase 11 country
- Efficacy, Safety, Pharmacokinetics and Pharmacodynamics Study, Assessing Multiple LNP023 Doses in Adult Patients With Paroxysmal Nocturnal HemoglobinuriaCompletedNCT03896152Phase 24 countries
- Study of Safety, Efficacy, Tolerability, Pharmacokinetics and Pharmacodynamics of LNP023 in in Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH)CompletedNCT03439839Phase 23 countries
- Warmed Blood Transfusion in Premature InfantsActive, not recruitingNCT06425783Not applicable1 country
- Diet Therapy in Hemodialysis PatientsCompletedNCT06215339Not applicable1 country
- The Effect of Coolsense Method on Pain and Comfort in Hemodialysis PatientsCompletedNCT06144801Not applicable1 country
- Impact of Cardiopulmonary Bypass Flow on Renal Oxygenation, Blood Flow and Tubular InjuryCompletedNCT04084301Not applicable1 country
- The Effect Of Vıdeo-Based Fıstula Care Educatıon On HemodıalysısCompletedNCT05962268Not applicable1 country
- Dietary Fiber and Hyperkalemia in Dialysis PatientsCompletedNCT058604911 country
- Optimization of Prime Fluid Strategy to Preserve Microcirculatory Perfusion During Cardiac Surgery With Cardiopulmonary Bypass, Part IIStatus unknownNCT05647200Not applicable1 country
- Effect of Triflow Breathing TrainingCompletedNCT05809765Not applicable1 country
- Laughter Therapy Application in Hemodialysis PatientsCompletedNCT05576701Not applicable1 country
- Lavare Cycle in Patients Receiving HeartWare Left Ventricular Assist DeviceTerminatedNCT04199793Not applicable1 country
- Immunogenicity and Safety of BBIBP-Corv Coadministered With PPV23 and IIV4 in Hemodialysis PopulationStatus unknownNCT05480436Phase 41 country
- Observational Study of Elizaria® in aHUS PatientsCompletedNCT047498101 country