An observational study in Heart Surgery, Blood Transfusion and Hemolysis, sponsored by Boston Children's Hospital. Recruiting at 1 site in United States. Open to participants aged 0 Years to 17 Years. Per ClinicalTrials.gov, last updated 2026-01-07.
Sponsored by Boston Children's Hospital · Observational
This study aims to learn more about blood management in children undergoing heart surgery, such as the right amounts, and the best blood products, to administer. It also aims to develop a mathematical model that may help researchers better predict and treat patients who need blood transfusions during heart surgery.
120 studies on the registry are indexed under Hemolysis; 22 are open to participants now.
This study's planned enrollment of 50 is below the median of 80 across 33 observational studies indexed under Hemolysis.
Browse Hemolysis studies →Boston Children's Hospital is the lead sponsor of 608 studies on the registry; 147 are open to participants now.
Of its 32 completed or terminated interventional studies of FDA-regulated products, 19 (59%) have results posted.
Counted across the registry records on this site, refreshed daily.
Pediatric patients under 18 years of age undergoing cardiac surgery with clear prime on cardio-pulmonary bypass (CPB) at Boston Children's Hospital (BCH).
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Exclusion Criteria:
Children under 18 years of age having heart surgery with cardio-pulmonary bypass at Boston Children's Hospital
Other: blood sampling
Discarded blood samples will be taken from routine clinical labs drawn during and after heart surgery.
Intraoperative hemolysis during pediatric cardiac cardio-pulmonary bypass (CPB) cases as assessed using the plasma free hemoglobin assessment
Time frame: 1 day (during cardio-pulmonary bypass)
In vitro salvaged red blood cells (RBCs) co-incubation with patients' plasma for hemolysis assessment compared to patients' baseline RBCs
Time frame: 1 day
Plan to share: No
No publications or documents are linked to this record.
Started Aug 2025 (actual). Primary completion is estimated for Dec 2026, 16 months after the start.
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