Gastroesophageal Reflux: all 1,086 studies

Page 4 of 11. Open to participants first (187), then studies with results posted, then the rest; newest registration first within each.

• Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Mild to Moderate Erosive Gastroesophageal Reflux Disease (GERD)CompletedNCT00658632Phase 3Results posted
• Rabeprazole Extended-Release 50 mg Versus Esomeprazole 40 mg for Healing and Symptomatic Relief of Moderate to Severe Erosive Gastroesophageal Reflux Disease (GERD)CompletedNCT00658528Phase 3Results posted
• Reflux Esophagitis Phase III Study (Maintenance Treatment)CompletedNCT00634114Phase 3Results posted
• Reflux Esophagitis Phase III Study (Initial Treatment)CompletedNCT00633932Phase 3Results posted
• A Study of Dexlansoprazole Modified Release Formulation to Treat Night HeartburnCompletedNCT00627016Phase 3Results posted
• Efficacy of Pantoprazole in Patients Older Than 12 Years With Reflux Associated Sleep Disorders (PULS)CompletedNCT00562094Results posted
• Efficacy of Pantoprazole in Patients Older Than 12 Years Who Have Symptoms of Non-Erosive Reflux Disease (NERD) or Erosive Gastroesophageal Reflux Disease (eGERD)CompletedNCT00561730Results posted
• Domperidone for Gastroparesis in Solid Organ TransplantationTerminatedNCT00552422Not applicableResults posted
• Role of Pain Modulation in GERD Patients Who Failed Standard Dose PPICompletedNCT00539240Phase 2/3Results posted
• COPD Patients Diagnosed With GERD,COPD Exacerbations After Treatment With High Dose PPITerminatedNCT00523367Not applicableResults posted
• ClosureFAST vs. Laser Ablation for the Treatment of GSV Disease: A Multicenter, Single-Blinded, Randomized Study.CompletedNCT00509392Phase 4Results posted
• Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in GastroparesisCompletedNCT00492622Phase 4Results posted
• Phase 3/Safety & Efficacy of Esomeprazole in InfantsCompletedNCT00468559Phase 3Results posted
• A Study to Compare the Number of Patients With Gastro-Oesophageal Reflux Disease (GORD) Achieving Heartburn and Regurgitation Symptom Resolution After Treatment With Either Rabeprazole Sodium 20mg, Esomeprazole 20mg or Esomeprazole 40mgCompletedNCT00464308Phase 4Results posted
• Nexium (Esomeprazole) in Symptom Adapted Therapy in GERD PatientsCompletedNCT00444275Phase 4Results posted
• Do Laryngeal Tissue Changes in Patients Suspected of Having Laryngopharyngeal Reflux Predict Response to Treatment?CompletedNCT00444145Phase 4Results posted
• Efficacy and Safety of Esomeprazole Once Daily for the Treatment of GERD in Neonatal PatientsCompletedNCT00427635Phase 3Results posted
• Randomized Intervention for Children With Vesicoureteral Reflux (RIVUR)CompletedNCT00405704Phase 3Results posted
• Symptom Improvements in Gastroesophageal Reflux Disease (GERD) PatientsCompletedNCT00394472Phase 2Results posted
• Efficacy of Dx-pH Probe in Diagnosing Extra-esophageal Reflux DiseaseCompletedNCT00388453Not applicableResults posted
• Feasibility of Placing Bravo PH Capsule in Proximal EsophagusCompletedNCT00378898Not applicableResults posted
• Safety and Efficacy Study of Axid Use in Infants Suffering From Gastroesophageal Reflux Disease (GERD)CompletedNCT00373334Phase 3Results posted
• Safety and Efficacy of Lansoprazole 30mg Twice Daily in Treatment of Laryngitis Associated With Gastroesophageal RefluxTerminatedNCT00369265Phase 4Results posted
• Study Evaluating the Efficacy and Safety of Pantoprazole in Infants With Symptomatic Gastroesophageal Reflux Disease (GERD)CompletedNCT00365300Phase 3Results posted
• Study Evaluating Pantoprazole in Neonates and Preterm Infants With GERDCompletedNCT00362609Phase 3Results posted
• Elucidation of Acid-Induced Pulmonary InflammationTerminatedNCT00361972Phase 2/3Results posted
• Endoscopic Implantation of Enteryx for the Treatment of GERDCompletedNCT00346905Not applicableResults posted
• Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat Gastroesophageal Reflux DiseaseCompletedNCT00321984Phase 3Results posted
• Study Evaluating Pantoprazole in Children With Gastroesophageal Reflux Disease (GERD)CompletedNCT00300755Phase 3Results posted
• Study Evaluating Pantoprazole Sodium Enteric-Coated Spheroid Suspension In Infants With Presumed GERDCompletedNCT00259012Phase 3Results posted
• Safety and Quality of Life Study of Dexlansoprazole Modified Release Formulation to Treat HeartburnCompletedNCT00255190Phase 3Results posted
• Esomeprazole (NEXIUM) vs. SurgeryCompletedNCT00251927Phase 3Results posted
• Safety and Efficacy of Dexlansoprazole Modified Release Formulation to Treat HeartburnCompletedNCT00251758Phase 3Results posted
• Efficacy and Safety of Dexlansoprazole Modified Release Formulation to Treat HeartburnCompletedNCT00251745Phase 3Results posted
• Investigation of the Association Between Nasal Polyposis and Extraesophageal Reflux DiseaseCompletedNCT00215787Not applicableResults posted
• Maintenance Intermittent Therapy for Symptomatic GERD PatientsCompletedNCT00165841Phase 2Results posted
• A Study of E3810 With Pre- and Post-Treatment pH Monitoring in Patients With Non-Erosive Gastroesophageal Reflux DiseaseCompletedNCT00165672Phase 3Results posted
• A Comparative Study on the Efficacy and Safety of E3810 in Patients With Non-erosive Gastroesophageal Reflux DiseaseCompletedNCT00165646Phase 3Results posted
• Study Evaluating Pantoprazole in Children With GERDCompletedNCT00141817Phase 3Results posted
• Treatment of Gastroesophageal Reflux Disease in 12-16 Year Old Patients With RabeprazoleCompletedNCT00132496Phase 2Results posted
• Medical Treatment for Gastroesophageal Reflux Disease (GERD) in Preterm InfantsCompletedNCT00131248Phase 3Results posted
• Sedation Depth and EGJ Endoscopic Grading: A Randomized Controlled TrialCompletedNCT07891455Not applicable
• Effect of Bioflor on Gut Microbiota in Proton-Pump Inhibitor UsersCompletedNCT07852676Phase 4
• Antireflux Mucosal Ablation vs Fundoplication for Refractory GERDCompletedNCT07842354
• AJYR+GV vs RYGB for GERDActive, not recruitingNCT07768202Not applicable
• One-year Clinical Outcomes of Endoscopic Cardia Banding Plication for Refractory Gastroesophageal Reflux Disease After Laparoscopic Sleeve GastrectomyCompletedNCT07749352Not applicable
• Mobile Application for Gastroesophageal Reflux DiseaseCompletedNCT07744815Not applicable
• Endoscopic Classification of Fundoplication Integrity Predicts Pathologic RefluxCompletedNCT07722663
• Biological Optimization Versus Standard Care in Post-POEM Achalasia Patients (BIO-POEM)Active, not recruitingNCT07620899Not applicable
• ECG and CXR for Predicting Cardiovascular DiseasesCompletedNCT07573852
• Effects of Clinical Pilates Exercises on Symptoms, Posture, Balance and Quality of Life in GERDCompletedNCT07573280Not applicable
• A Pre-market, Two-stages Interventional Clinical Investigation to Evaluate the Safety and the Performance of Fibroin Syrup in Reducing the Gastroesophageal Reflux Disease (GERD) Symptomatology in Nonerosive Reflux Disease (NERD) PatientsCompletedNCT07563790Not applicable
• Comparison of Esomeprazole Versus Vonoprazan in Gastroesophageal Reflux DiseaseCompletedNCT07563491Not applicable
• Impact of Crural Repair and Gastropexy During Laparoscopic Sleeve GastrectomyCompletedNCT07560787Not applicable
• Impact of GEA Simultaneous to VSG on Post-operative GERDActive, not recruitingNCT07537244Not applicable
• A Clinical Trial of PepZinGI® for Acute Heartburn Relief and Sleep OutcomesCompletedNCT07379645Not applicable
• Study to Evaluate the Effect of Food on the Pharmacokinetics and Pharmacodynamics Characteristics in Healthy Adult VolunteersCompletedNCT07364838Phase 1
• Evaluation of the Effectiveness of the Ezisurg Stapling (Ezi Endo Lite) During Laparoscopic Nissen Sleeve GastrectomyCompletedNCT07344935Not applicable
• A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Maintenance of Healing in Participants With Healed Erosive Esophagitis (EE) Due to Gastroesophageal Reflux Disease (GERD)WithdrawnNCT07313774Phase 3
• Alginate vs Sucralfate for GERD Symptomatic ReliefCompletedNCT07310927Phase 2/3
• A Study to Investigate the Effect of Linaprazan Glurate on the Pharmacokinetics of AmoxicillinCompletedNCT07308041Phase 1
• Comparing Two Different Methods of Ablation of Inlet Patches (APC vs RFA)Active, not recruitingNCT07252180Not applicable
• Evaluation of the Clinical Course of NERD and Assessment of the Esophageal Mucosa ResistanceActive, not recruitingNCT07174882
• Long-term Follow-up After OAGBCompletedNCT07125638
• Association Between Gastroesophageal Reflux Disease (GERD) Severity and Dental CariesCompletedNCT07108751
• Mass Balance Study of [14C]X842 in Healthy Adult Male SubjectsCompletedNCT07107672Phase 1
• BURDEN OF ESOPHAGEAL CANCER IN EOSINOPHILIC ESOPHAGITIS (ESCAPE STUDY)CompletedNCT07102329
• Modifications to Gastric Sleeve: Implications for GRED and Quality of LifeActive, not recruitingNCT07070908Not applicable
• Evaluation of the Efficacy and Safety of Eolo in Patients With NERDCompletedNCT07041060Not applicable
• A Study Comparing the Effect and Safety of Linaprazan Glurate to Lansoprazole in Participants With Erosive Esophagitis (EE) Due to Gastroesophageal Reflux Disease (GERD)CompletedNCT07037875Phase 3
• Comparative Analysis of Postoperative Manometry Outcomes in Nissen vs Toupet FundoplicationCompletedNCT06986902Not applicable
• Retrospective Observational Study on GERD Management in General Hospitals in KoreaCompletedNCT06974903
• Upper GI MM vs ManometryCompletedNCT06973070
• Observationa Study is a Prospective and Multi-institutional Observational Study.CompletedNCT06952855
• Efficacy of Gut-Brain Neuromodulators in the Treatment of Gastroesophageal Reflux DiseaseCompletedNCT06945237Not applicable
• Ultrasound Assessment for Comparison of Gastric Residual Volume After Ingestion of Carbohydrate Drink and Water in Obesity Class II and III Volunteers at Risk of AspirationCompletedNCT06941623Not applicable
• The Effect of Using Virtual Reality Glasses on Post-Care Pain and Comfort Level in Intensive Care PatientsCompletedNCT06923982Not applicable
• Efficacy and Safety of Ondansetron Versus Metaclopromide Treatment in Infants With Gastro Oesophageal RefluxCompletedNCT06898268Not applicable
• Telehealth-Delivered Gut-Directed Hypnotherapy for Managing GI HealthCompletedNCT06890663Not applicable
• The Anti-gastroesophageal Reflux Effect of Anvitra Gastric Suspension on Outpatients With Gastroesophageal Reflux DiseaseCompletedNCT06889246Not applicable
• Development of Machine Learning Models to Predict Postoperative GERD Symptom Resolution After Laparoscopic Nissen FundoplicationActive, not recruitingNCT06862037
• Postoperative Gastroesophageal Reflux Symptoms After Laparoscopic Sleeve Gastrectomy Based on the Presence of Preoperative SymptomsActive, not recruitingNCT06835933
• Breathing Exercises in Patients With Gastroesophageal RefluxCompletedNCT06812650Not applicable
• Efficacy of Dietary Supplement in Subjects With Acid Reflux and/or Abdominal Bloating/Distention and GI SymptomsCompletedNCT06808867Not applicable
• Therapeutic Effect of Vonoprazan Versus Dexlansoprazole in Treatment of Gastroesophageal Reflux DiseaseCompletedNCT06778395Phase 4
• Evaluation of Upper Esophageal Sphincter Motor Activity in Patients with Extra Esophageal Reflux SymptomsActive, not recruitingNCT06773702
• Preserving the Pre-cardial Fat Pad During Sleeve Gastrectomy on Postoperative Gastroesophageal RefluxActive, not recruitingNCT06732661Not applicable
• Effect of Two Different Doses of Neostigmine on the Gastric Residual Volume and Aspiration in Critically Ill PatientsCompletedNCT06687187
• Polaprezinc (Zinc L-carnosine) in Infants With Gastroesophageal RefluxCompletedNCT06678997Not applicable
• Epidemiological Studies and Risk Factor Analysis of GERD in Xiamen CityCompletedNCT06585176
• Risk of Gastric Reflux During Tulip vs GMA(Glottis Mask Airway) AirwayCompletedNCT06527352Not applicable
• Effect of Fermented Soybean (FSB) Supplementation on Gas-troesophageal Reflux Disease (GERD)CompletedNCT06524271Not applicable
• A Liquid Biopsy for High-risk Pre-cancer Screening of Esophageal AdenocarcinomaCompletedNCT06381583
• Investigation of the Transmission Pathways of Reflux in Patients With Chronic Venous InsufficiencyCompletedNCT06369207
• A 3-Arm Study Comparing the Efficacy of Anti-Reflux Reconstruction Protocols After Laparoscopic Proximal GastrectomyCompletedNCT06347757Not applicable
• Establishing Pressures at the EGJ During Diaphragmatic Breathing Using High-resolution Esophageal ManometryCompletedNCT06329583Not applicable
• Osteopathic Manipulative Treatment for Gastro-oesophageal Reflux DiseaseTerminatedNCT06317675Phase 2
• Thresholds of SLR Maneuver in Obese PatientsCompletedNCT06222177
• Effect of Glossopharyngeal Nerve Block on Pharyngeal Dysphagia Induced by Gastroesophageal Reflux DiseaseWithdrawnNCT06215794Not applicable
• Clinical Effect of Stellate Ganglion Block on Gastroesophageal Reflux DiseaseWithdrawnNCT06215742Not applicable

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