Status unknownNCT03180658Updated Jun 8, 2017

Concentrated Growth Factors in Regenerative Therapy in Furcation Involvements in Humans

An interventional study of GTR + CGF + bone graft and CGF + bone graft in Concentrated Growth Factors, Periodontal Regeneration and Furcation Defects, sponsored by Jing Qiao. Status unknown at 1 site in China. Open to participants aged 18 Years to 70 Years, including healthy volunteers. Per ClinicalTrials.gov, last updated 2017-06-08.

Sponsored by Jing Qiao · Not applicable, Interventional, and Treatment

The sponsor has not verified this record recently (last verified Jun 2017), so the status shown — last known as Recruiting — may be out of date.

Phase: Not applicable
Study type: Interventional
Enrollment: 30
Allocation: Randomized
Ages: 18 Years to 70 Years
Sex: All

Study summary

Objective: To compare the effect of guided tissue regeneration (GTR) + concentrated growth factors (CGF) + bone graft and CGF + bone graft in the treat of II° furcations of human mandibular molars. Methods: At least thirty II°furcation involvements in mandibular molars will be included and randomly divided into two groups. The experimental group will accept GTR + CGF + bone graft therapy, and the control group will accept CGF + bone graft therapy. The clinical examination and cone beam computed tomography (CBCT) will be performed at baseline and 1 year post-surgery.

Conditions studied

Concentrated Growth Factors
Periodontal Regeneration
Furcation Defects

Browse trials for

Furcation Defects 46

Who can participate

Ages eligible: 18 Years to 70 Years
Sexes eligible: All
Accepts healthy volunteers: Yes

Inclusion criteria

II° furcation involvements in mandibular molars
after periodontal therapy.

Exclusion criteria

Exclusion Criteria:

not healthy

Study design

Phase: Not applicable
Primary purpose: Treatment
Allocation: Randomized
Intervention model: Parallel assignment
Masking: Double (Participant, Outcomes assessor)
Enrollment: 30 participants (estimated)

Study arms

Experimental
experimental
GTR+CGF+bone graft, CGF
Procedure: GTR + CGF + bone graft
Active comparator
controlled
CGF+bone graft
Procedure: CGF + bone graft

Interventions

ProcedureGTR + CGF + bone graft
Guided tissue regeneration (GTR) combined with CGF and bone graft to treat mandibular furcation involvements
Also known as: CGF Centrifuge machine
ProcedureCGF + bone graft
CGF combined with bone graft to treat mandibular furcation involvements
Also known as: CGF Centrifuge machine

What researchers measure

Primary outcomes

clinical measurement
Probing depth
Time frame: 1 year
clinical parameter
clinical attachment loss
Time frame: 1 year

Secondary outcomes

radiographic parameter
cone beam computerized tomographic scanning
Time frame: 1 year

Study locations

1 of 1 sites recruiting

Peking university School and Hospital of Stomatology
Beijing, Beijing 100081, China
- jing qiao, doctor · Contact
Recruiting

References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

Registry details

Key details

Study ID: NCT03180658
Lead sponsor: Jing Qiao
Responsible party: Jing Qiao (Principal Investigator, Peking University) — Sponsor-investigator
First posted: Jun 8, 2017
Start date: May 1, 2017
Primary completion: May 1, 2020 (estimated)
Completion: Jul 1, 2020 (estimated)
Last update: Jun 8, 2017

Study contacts

qiao jing, doctor

Contact

donaldshushu@aliyun.com

86-13241892143

yan zu zhang, doctor

study chair · dean

Oversight

Data monitoring committee: Yes
FDA-regulated drug: No
FDA-regulated device: No

View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is status unknown, as verified in Jun 2017. You cannot join it, but the record below documents what was studied.

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