Radiation Fibrosis Syndrome clinical trials
The registry lists 19 studies for Radiation Fibrosis Syndrome across 9 countries. 6 are recruiting or about to start. 4 of them are mainly about Radiation Fibrosis Syndrome (how this is decided). Per ClinicalTrials.gov, last updated 2026-06-18.
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Breast cancer · Recruiting: 2 came in, 3 changed
What changed in your saved searches, Oct 31 – Nov 6:
A study of drug A after surgery for early breast cancer
Came in · now Recruiting
Drug B with hormone therapy in advanced breast cancer
Changed
· Sites: 4 added, including Seoul and Busan
· Enrollment: 300 → 450 participants
Exercise during chemotherapy
Now Active, not recruiting
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Who runs them
Massachusetts General Hospital (2) · Radiation Therapy Oncology Group (2) · St. James's Hospital, Ireland (1) · Meshalkin Research Institute of Pathology of Circulation (1) · University of South Florida (1) · Federal University of Health Science of Porto Alegre (1) · Xinqiao Hospital of Chongqing (1) · University of Chicago (1)
What is being tested here
Drugs under test in Radiation Fibrosis Syndrome studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Budesonide | 1 | 0 | 1 |
| CBP-8 gallium GA-68 | 1 | 0 | 1 |
| Losartan | 0 | 0 | 3 |
| Endostar protein | 0 | 0 | 1 |
| Pirfenidone | 0 | 0 | 1 |
| Captopril | 0 | 0 | 1 |
| Hyperbaric Oxygen | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 4
- Nov 2026Ultrasonic Perfusion Imaging in Post-mastectomy Irradiated Patients · Mayo Clinic
- Dec 2026Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer Patients · Instituto Nacional de Cancerologia de Mexico
- May 2027Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue Injury · Massachusetts General Hospital
- Aug 2027Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer Patients · Shaw Cancer Center
Who these studies take
Of the 4 Radiation Fibrosis Syndrome studies recruiting now, 2 (50%) set no upper age limit and 1 (25%) stop at 75 or younger. 0 (0%) take children under 18. 1 (25%) are for women only and 0 (0%) for men only; 0 (0%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 0 (0%) | 0 (0%) |
| 18 | 4 (100%) | 3 (75%) |
| 30 | 4 (100%) | 3 (75%) |
| 40 | 4 (100%) | 3 (75%) |
| 50 | 4 (100%) | 3 (75%) |
| 65 | 4 (100%) | 3 (75%) |
| 75 | 4 (100%) | 3 (75%) |
| 85 | 2 (50%) | 1 (25%) |
Across all 19 studies, recruiting or not: 11% stop at 75 or younger and 5% at 65; 5% take children; 32% are for women only and 0% for men only; 0% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 19 of 19. search them.
- Ultrasonic Perfusion Imaging in Post-mastectomy Irradiated PatientsEnrolling by invitationNCT04992650Not applicable1 country
- Prophylactic Inhaled Steroids to Reduce Radiation Pneumonitis Frequency and Severity in Lung Cancer PatientsRecruitingNCT03803787Phase 21 country
- Impact of Photobiomodulation (PBM) on Biomarkers of Radiation Lymphedema and Fibrosis in Head and Neck Cancer PatientsRecruitingNCT06708754Not applicable1 country
- Evaluation of PET Probe [68Ga]CBP8 in the Detection of Radiation Induced Tissue InjuryRecruitingNCT04485286Phase 21 country
- Home-Based Photo-Biomodulation for Management of Lymphoedema and Radiation Fibrosis in Patients After Head and Neck Cancer: A Single-Arm Feasibility TrialNot yet recruitingNCT07139782Not applicable1 country
- Radiotherapy Exposed Lung Injury: Effect on Functioning - CohortRecruitingNCT060691151 country
- Losartan to Reduce Radiation Induced Fibrosis in Breast Cancer PatientsActive, not recruitingNCT05637216Phase 21 country
- Autologous Fat Grafting in Radiated Soft Tissue ReconstructionCompletedNCT058901961 country
- Losartan in Prevention of Radiation-Induced Heart FailureCompletedNCT05607017Early Phase 11 country
- Clinical Study of Endostatin in Improving Radiation Pneumonia and FibrosisCompletedNCT03796364Phase 21 country
- Image-Guided Radiation Therapy in Treating Patients With Primary Soft Tissue Sarcoma of the Shoulder, Arm, Hip, or LegCompletedNCT00589121Phase 22 countries
- PhysioTouch for Treatment of Radiation FibrosisWithdrawnNCT03496909Not applicable
- Physiotherapy for Radiation-induced TrismusCompletedNCT02094690Not applicable1 country
- Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary PhysiologyCompletedNCT034625241 country
- Captopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without ChemotherapyTerminatedNCT00077064Phase 21 country
- Losartan in Treating Pulmonary Fibrosis in Patients With Stage I, II, or III Non-Small Cell Lung CancerWithdrawnNCT00880386Not applicable
- Hyperbaric Oxygen Therapy Compared With Standard Therapy in Treating Chronic Arm Lymphedema in Patients Who Have Undergone Radiation Therapy for CancerStatus unknownNCT00077090Phase 21 country
- IH636 Grape Seed Extract in Treating Hardening of Breast Tissue in Women Who Have Undergone Radiation Therapy for Early Breast CancerStatus unknownNCT00041223Phase 21 country
- Pirfenidone in Treating Patients With Fibrosis Caused by Radiation Therapy for CancerCompletedNCT00020631Not applicable1 country