Eye Neoplasms clinical trials
The registry lists 32 studies for Eye Neoplasms across more than 10 countries. 4 are recruiting or about to start. 8 of them are mainly about Eye Neoplasms (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-22. Counting its 4 narrower conditions too, such as Uveal Melanoma: 577 studies, 84 open.
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Who runs them
Aura Biosciences (5) · M.D. Anderson Cancer Center (3) · National Cancer Institute (NCI) (3) · Memorial Sloan Kettering Cancer Center (2) · St. Jude Children's Research Hospital (1) · University of Cincinnati (1) · Royal Liverpool University Hospital (1) · The Hospital for Sick Children (1)
What is being tested here
Drugs under test in Eye Neoplasms studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 5, phase 3 first
- Nov 2027A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal Melanoma · Phase 3 · Aura Biosciences
- Nov 2026Suprachoroidal Administration in Subjects With Metastases to the Choroid · Aura Biosciences
- Dec 2026MRI in Diagnosing Solid Tumors of the Eye and Orbit · University of Cincinnati
- Dec 2026Intraoperative OCT Guidance of Intraocular Surgery II · Duke University
- Oct 2027A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant Melanomas · Novartis Pharmaceuticals
Who these studies take
Of the 4 Eye Neoplasms studies recruiting now, 4 (100%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (25%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (25%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (25%) | 1 (25%) |
| 18 | 4 (100%) | 4 (100%) |
| 30 | 4 (100%) | 4 (100%) |
| 40 | 4 (100%) | 4 (100%) |
| 50 | 4 (100%) | 4 (100%) |
| 65 | 4 (100%) | 4 (100%) |
| 75 | 4 (100%) | 4 (100%) |
| 85 | 4 (100%) | 4 (100%) |
Across all 32 studies, recruiting or not: 13% stop at 75 or younger and 13% at 65; 41% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
Studies
Recruiting first, then most recently updated. Showing 32 of 32. search them.
- Intraoperative OCT Guidance of Intraocular Surgery IIRecruitingNCT037132681 country
- Suprachoroidal Administration in Subjects With Metastases to the ChoroidRecruitingNCT06643884Phase 21 country
- A Study Comparing Two Optical Coherence Tomography Devices in People With Ocular TumorsRecruitingNCT07449195Not applicable1 country
- Evaluation of the Safety, Efficacy, and Pharmacokinetics of NBM-BMX in Patients With Metastatic Uveal MelanomaRecruitingNCT07136181Phase 1/21 country
- Choroidal Melanoma Patient-Reported Outcome Study (CM-PRO) in a Subset of AU-011-301 (CoMpass) SubjectsActive, not recruitingNCT074217391 country
- A Phase 3 Randomized, Masked, Controlled Trial to Evaluate Efficacy and Safety of Belzupacap Sarotalocan (AU-011) Treatment Compared to Sham Control in Subjects With Primary Indeterminate Lesions or Small Choroidal MelanomaActive, not recruitingNCT06007690Phase 314 countries
- A Phase I/II Study of DYP688 in Patients With Metastatic Uveal Melanoma and Other GNAQ/11 Mutant MelanomasActive, not recruitingNCT05415072Phase 1/27 countries
- Binimetinib Plus Belinostat for Subjects With Metastatic Uveal MelanomaActive, not recruitingNCT05170334Phase 21 country
- Superb Microvascular Intraocular Tumor Imaging Study (SMITIS)Active, not recruitingNCT05051384Not applicable1 country
- Study of Treatment for Patients With Cancer of the Eye -RetinoblastomaCompletedNCT00186888Phase 31 country
- MRI in Diagnosing Solid Tumors of the Eye and OrbitActive, not recruitingNCT01653080Not applicable1 country
- Phase 2 Trial to Evaluate Belzupacap Sarotalocan (AU-011) Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal MelanomaCompletedNCT04417530Phase 21 country
- Topotecan Episcleral Plaque for Treatment of RetinoblastomaCompletedNCT04428879Phase 11 country
- Artificial Intelligence-assisted Screening of Malignant Pigmented Tumors on the Ocular SurfaceCompletedNCT056453411 country
- Vaccine Therapy in Treating Patients With Metastatic CancerCompletedNCT00020267Phase 11 country
- Vaccine Therapy in Treating Patients With Metastatic Melanoma of the EyeCompletedNCT00020475Phase 21 country
- Study in Subjects With Small Primary Choroidal MelanomaCompletedNCT03052127Phase 1/21 country
- BCC Excision RevisitedCompletedNCT058533151 country
- Use of an Allograft Set-up (SclerFIX) as Replacement of Sclera Graft for Support of Enucleation ImplantCompletedNCT05236049Phase 11 country
- Research of Pathological Imaging Diagnosis of Ocular Tumors Based on New Artificial Intelligence AlgorithmStatus unknownNCT04695015
- Melanoma Vaccine With Peptides and LeuprolideCompletedNCT00254397Phase 21 country
- Optical Coherence Tomography of Retinal Abnormalities Associated With Choroidal Nevus, Choroidal Melanoma and Choroidal Melanoma Treated With Iodine-125 BrachytherapyTerminatedNCT003463721 country
- Study of D-Methadone in Patients With Chronic PainCompletedNCT00588640Phase 1/21 country
- Intra-arterial Chemotherapy With Melphalan for the Treatment of Retinoblastoma (RTB) in Advanced Intraocular StageTerminatedNCT01393769Phase 21 country
- B-Receptor Signaling in CardiomyopathyCompletedNCT011358491 country
- New Biopsy Technique for Uveal MelanomaCompletedNCT019249231 country
- Proton Beam Radiation Therapy for Intraocular and Periocular RetinoblastomaTerminatedNCT00432445Phase 21 country
- Social-Psychological Aspects of Orbital ExenterationCompletedNCT006017441 country
- A Phase II Study of Isolated Hepatic Perfusion (IHP) in Patients With Ocular MelanomaCompletedNCT00062933Phase 21 country
- Intra-arterial Chemotherapy for Advanced Intraocular RetinoblastomaWithdrawnNCT01151748Phase 21 country
- Quality of Life of Eye Amputated Patients in DenmarkCompletedNCT010722531 country
- Pain Relief - Tramadol Versus IbuprofenStatus unknownNCT00111046Phase 1/21 country