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Esophageal Achalasia clinical trials

The registry lists 143 studies for Esophageal Achalasia across more than 10 countries. 44 are recruiting or about to start. 133 of them are mainly about Esophageal Achalasia (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-12.

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Status

Completed
50
Recruiting
31
Status unknown
29
Terminated
9
Not yet recruiting
8
Withdrawn
7

Phase

Phase 2
11
Phase 3
7
Phase 4
7
Phase 1
3
Early Phase 1
1

Where

United States
52
China
17
India
9
Italy
9
Canada
7
France
7

Who runs them

Asian Institute of Gastroenterology, India (7) · Chinese University of Hong Kong (6) · Shanghai Zhongshan Hospital (6) · Baylor College of Medicine (5) · Northwestern University (5) · Johns Hopkins University (5) · Mayo Clinic (5) · Universitätsklinikum Hamburg-Eppendorf (3)

What is being tested here

Drugs under test in Esophageal Achalasia studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted

DrugOpenPhase 3All
Botulinum toxin type A112
Valacyclovir101
Acyclovir101
Shingrix101
Ropivacaine001
Olinciguat001
Mirabegron001
Esomeprazole001
Oxycodone001
Prednisone001

Coming up

4phase 3 studies under way
9studies finish main data collection within a year

Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.

All 9

Who these studies take

Of the 31 Esophageal Achalasia studies recruiting now, 20 (65%) set no upper age limit and 5 (16%) stop at 75 or younger. 3 (10%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (3%) take healthy volunteers.

Recruiting studies that take each age, of 31
AgeWomenMen
103 (10%)3 (10%)
1831 (100%)31 (100%)
3030 (97%)30 (97%)
4030 (97%)30 (97%)
5030 (97%)30 (97%)
6529 (94%)29 (94%)
7528 (90%)28 (90%)
8524 (77%)24 (77%)

Across all 143 studies, recruiting or not: 22% stop at 75 or younger and 7% at 65; 10% take children; 0% are for women only and 0% for men only; 9% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.

How long Esophageal Achalasia studies take

Of 32 interventional studies with no phase under Esophageal Achalasia, half reached primary completion within 44 months of starting, counting those still running.

Start to primary completionEvery sponsorIndustryNon-industry
Interventional, no phase44 mo21–63 · 32 studies——

Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out

What changed recently

From the registry's own updates since Oct 15, 2026.

Newly registered1

Studies

Recruiting first, then most recently updated. Showing 50 of 143. Browse all 143 → or search them.