Endophthalmitis clinical trials
The registry lists 65 studies for Endophthalmitis across more than 10 countries. 9 are recruiting or about to start. 50 of them are mainly about Endophthalmitis (how this is decided). Per ClinicalTrials.gov, last updated 2026-10-22.
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Who runs them
National University of Malaysia (3) · Benha University (3) · University of Campinas, Brazil (3) · Federal University of São Paulo (3) · National Eye Institute (NEI) (2) · Universidade Federal de Pernambuco (2) · University of Milan (1) · Matthew Bolton (1)
What is being tested here
Drugs under test in Endophthalmitis studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| Moxifloxacin | 1 | 3 | 9 |
| Levofloxacin | 0 | 0 | 2 |
| Bromfenac | 0 | 0 | 1 |
| Omaveloxolone | 0 | 0 | 1 |
| Hypochlorous Acid | 0 | 1 | 1 |
| Dexamethasone | 0 | 0 | 1 |
| Mupirocin | 0 | 0 | 1 |
| Gentamicins | 0 | 0 | 1 |
| Clindamycin | 0 | 0 | 1 |
| Cefuroxime | 0 | 0 | 1 |
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
The study
- Dec 2026Nanopore Sequencing in Ophthalmology · Medical University of Graz
Who these studies take
Of the 5 Endophthalmitis studies recruiting now, 4 (80%) set no upper age limit and 0 (0%) stop at 75 or younger. 1 (20%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 1 (20%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 1 (20%) | 1 (20%) |
| 18 | 5 (100%) | 5 (100%) |
| 30 | 5 (100%) | 5 (100%) |
| 40 | 5 (100%) | 5 (100%) |
| 50 | 5 (100%) | 5 (100%) |
| 65 | 5 (100%) | 5 (100%) |
| 75 | 5 (100%) | 5 (100%) |
| 85 | 5 (100%) | 5 (100%) |
Across all 65 studies, recruiting or not: 8% stop at 75 or younger and 5% at 65; 26% take children; 0% are for women only and 0% for men only; 14% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
What changed recently
From the registry's own updates since Oct 13, 2026.
Newly registered1
- Vitrectomy Combined With Povidone-Iodine Vitreous Irrigation for Infectious EndophthalmitisOct 22, 2026NCT07888205
Studies
Recruiting first, then most recently updated. Showing 50 of 65. Browse all 65 → or search them.
- Vitrectomy Combined With Povidone-Iodine Vitreous Irrigation for Infectious EndophthalmitisNot yet recruitingNCT07888205Not applicable
- Nanopore Sequencing in OphthalmologyRecruitingNCT053728611 country
- Safety and Efficacy of Intracameral Zimoxin for Prevention of Endophthalmitis After Cataract SurgeryNot yet recruitingNCT03244072Phase 2/31 country
- Vascular Changes Associated With Endophthalmitis.RecruitingNCT071753111 country
- Complex Ocular Infection, Optimization of Microbiological DiagnosisRecruitingNCT054323361 country
- Evaluation and Risk Factors of Post-traumatic EndophthalmitisNot yet recruitingNCT06673784
- Efficacy and Safety of Topical Cyclosporine 0.05% and Lifitgrast on the Ocular Surface Symptom After Photorefractive Keratectomy in Feiz Hospital, Isfahan, 2024Not yet recruitingNCT06624384Phase 11 country
- Ozurdex Endophtamitis Cohort, Prognostic Assessment at 12 MonthsRecruitingNCT062685611 country
- Endophthalmitis Post Intravitreal InjectionsRecruitingNCT04035369Not applicable1 country
- Phacovitrectomy Versus Pars Plana Vitrectomy Alone for Post-Intravitreal Injection EndophthalmitisCompletedNCT07717944Not applicable1 country
- First-line Surgical Versus Medical Treatment: A Retrospective Study From 2014 to 2024 in Brest (BRESTE)CompletedNCT075148451 country
- Targeting Immunosuppressive Treatment for Non-infectious Uveitis Using Aqueous Humor Cytokine ProfilesActive, not recruitingNCT07262437Not applicable1 country
- Demographics and Clinical Characteristics of Ocular Inflammatory Diseases in SingaporeActive, not recruitingNCT071761301 country
- A Feasibility Randomised Controlled Trial of Early Vitrectomy for Post-operative Exogenous EndophthalmitisCompletedNCT04522661Not applicable1 country
- Bromfenac Versus Dexamethasone After Cataract SurgeryCompletedNCT03317847Phase 41 country
- RTA 408 Ophthalmic Suspension for the Treatment of Ocular Inflammation and Pain Following Ocular SurgeryCompletedNCT02065375Phase 21 country
- Compare PPV With and Without Silicone Oil in Managing Postoperative EndophthalmitisCompletedNCT06990607Not applicable1 country
- Clinical Features and Visual Prognosis of Infectious EndophthalmitisCompletedNCT067551771 country
- Evaluation do Early Pars Plana Vitrectomy in Acute EndophthalmitisCompletedNCT04192994Not applicable1 country
- Effectiveness and Safety of 0.5% Moxifloxacin Hydrochloride Ophthalmic Solution in Perioperative Sterilization in Patients Undergoing Ophthalmic SurgeryCompletedNCT054139801 country
- A Study of the Incidence of Intraocular Inflammation and Suspected Endophthalmitis Among Patients Treated With Aflibercept, Vial and Pre-filled Syringe, 2014-2022CompletedNCT057916951 country
- A Two Chemoprophylaxis Approaches After Phacoemulsification SurgeryCompletedNCT03634852Phase 4
- Study of Intraocular Concentrations (Aqueous Humor, Vitreous Humor) of Antibiotics After Local and/or Systemic Administration in EndophthalmitisStatus unknownNCT03968341Not applicable1 country
- Hypochlorous Acid Disinfection Prior to Cataract SurgeryCompletedNCT04568213Phase 31 country
- Evaluation of Macular Changes After Intracameral Moxifloxacin for Prevention of EndophthalmitisCompletedNCT03363295Phase 41 country
- Intravitreal Triamcinolone and Moxifloxacin Injection After Cataract SurgeryCompletedNCT05428683Not applicable1 country
- Intracameral Antibiotic Safety StudySuspendedNCT02590523Phase 31 country
- Early Vitrectomy for Endophthalmitis After Cataract SurgeryCompletedNCT052494131 country
- Safety and Efficacy of Topical Moxifloxacin for Prevention of Post-Traumatic Endophthalmitis: Randomized Controlled Clinical TrialStatus unknownNCT05162625Phase 21 country
- Use Of Intracameral Moxifloxacin For Prophylaxis Of Open Globe EndophthalmitisStatus unknownNCT05079854Phase 41 country
- The EXPLORE Study - The Use of Binocular OCT Imaging for the Assessment of Ocular DiseaseCompletedNCT035530171 country
- The Clinical Safety of Levofloxacin 1.5% vs Topical Moxifloxacin 0.5%Status unknownNCT04212429Phase 1/21 country
- The Pharmacokinetics of Topical Levofloxacin 1.5% vs Topical Moxifloxacin 0.5%Status unknownNCT04214821Phase 1/21 country
- Intracameral Levofloxacin (0.5%) vs Intracameral CefuroximeStatus unknownNCT04212078Phase 1/21 country
- Combined Endophthalmitis and Orbital Cellulitis in Patients With Novel Coronavirus Disease (COVID-19)CompletedNCT044565561 country
- Postoperative Safety Outcomes of Intraoperative Intracameral Preservative-Free Moxifloxacin Versus LevofloxacinCompletedNCT04403334Phase 41 country
- OTX-14-002: Device Exposure RegistryWithdrawnNCT02309736
- Multiplex Strip Polymerase Chain Reaction for Diagnosis of Eye Infection Diseases From Corneal Scraping SamplesStatus unknownNCT040756691 country
- Dosage Study for Vigamox Eye Drops Prior to Intravitreal InjectionsCompletedNCT00690313Phase 41 country
- A Clinical Study to Assess the Efficacy and Safety of Dexamethasone Suspension for Cataract SurgeryCompletedNCT03687931Phase 1/21 country
- Conjunctival Flora Before Cataract Surgery: a Microbiological EvaluationCompletedNCT03958292Not applicable1 country
- Intracameral Moxifloxacin for Prevention of Postcataract EndophthalmitisCompletedNCT02595359Phase 21 country
- Nylon Verus Polyglactin Corneal Suture in Pediatric Cataract SurgeryStatus unknownNCT03812640Not applicable1 country
- Interest of Intravitreal Corticotherapy as the First-line Treatment for Post-operative EndophthalmitisCompletedNCT01768078Phase 31 country
- Evaluation of Inflammation of the Anterior Segment by Laser Flashmeter in Patients Having Undergone Surgery of the Posterior Segment (Vitrectomy or Preindentation) During the First Postoperative Year. (FLAVIC)Status unknownNCT03677700
- Evaluation of Efficacy and Safety of Intracameral Moxifloxacin for Prevention of Postcataract Endophthalmitis.TerminatedNCT02770729Phase 31 country
- Preoperative Topical Gatifloxacin on Anterior Chamber Cultures After Cataract SurgeryWithdrawnNCT00335231Not applicable1 country
- Concentrating on Antisepsis: 5% vs. 10% Povidone-Iodine Prior to Intravitreal InjectionStatus unknownNCT03420820Not applicable
- Screening for NEI Clinical StudiesCompletedNCT000017341 country
- Endophthalmitis CulturesTerminatedNCT014967941 country