Omaveloxolone clinical trials

Studies by the year they started

16 studies that test it; most in 2025 (4)

Who runs them

Industry 16 · Other 0

Biogen (16)

Often tested with

Tested in the same studies.

Ipilimumab (1) · Nivolumab (1)

Studies

Open first, then newest update. How each study uses omaveloxolone is read from its arms, and is right about nine times in ten.

Testing it · 16

• A Study to Learn More About the Effects and Long-Term Safety of Omaveloxolone (BIIB141) in Children and Teens With Friedreich's AtaxiaActive, not recruitingPhase 3BiogenNCT06953583Written as Omaveloxolone
• A Study to Find Out How BIIB141 (Omaveloxolone) is Processed in the Body and to Learn More About Its Safety in Participants With Friedreich's Ataxia Aged 2 to 15 Years OldActive, not recruitingPhase 1BiogenNCT06054893Written as Omaveloxolone
• A Study to Learn How the Body Processes BIIB141 (Omaveloxolone) When Taken as a Capsule or as a Tablet Dissolved in Liquid, and to Learn About Its Safety in Healthy Adults Ages 18 to 55CompletedPhase 1BiogenNCT07297199Written as Omaveloxolone
• A Study to Learn if Taking BIIB141 (Omaveloxolone) Affects How Omeprazole is Processed in the Body and About BIIB141's Safety in Healthy Adults Aged 18 to 55CompletedPhase 1BiogenNCT07149415Written as Omaveloxolone
• A Study to Learn How BIIB141 (Omaveloxolone) is Processed in the Body When Taken as Capsules Compared to Sprinkled on Yogurt in Healthy Adults Aged 18 to 55CompletedPhase 1BiogenNCT07019064Written as Omaveloxolone
• RTA 408 Capsules in Patients With Melanoma - REVEALCompletedPhase 1/2BiogenNCT02259231Written as Omaveloxolone Capsules (2.5 mg/capsule)
• RTA 408 Ophthalmic Suspension for the Treatment of Ocular Inflammation and Pain Following Ocular SurgeryCompletedPhase 2BiogenNCT02065375Written as Omaveloxolone Ophthalmic Suspension 1.0%
• An Open-label DDI Study of Omaveloxolone in Healthy SubjectsCompletedPhase 1BiogenNCT05909644Written as Omaveloxolone
• A Clinical Drug-Drug Interaction (DDI) Study With OmaveloxoloneCompletedPhase 1BiogenNCT04008186Written as Omaveloxolone
• A Human AME Study for OmaveloxoloneCompletedPhase 1BiogenNCT03931590Written as [14C]-Omaveloxolone
• A TQTc Study for OmaveloxoloneCompletedPhase 1BiogenNCT05927649Written as Omaveloxolone
• A Pharmacokinetic Study of Omaveloxolone in Subjects With Hepatic Impairment and Normal Hepatic FunctionCompletedPhase 1BiogenNCT03902002Written as Omaveloxolone 50 mg capsules
• A Pharmacokinetic Study of Omaveloxolone in Healthy VolunteersCompletedPhase 1BiogenNCT03664453Written as omaveloxolone
• RTA 408 in the Treatment of Advanced Solid Tumors (NSCLC & Melanoma) - DISCOVERCompletedPhase 1BiogenNCT02029729Written as omaveloxolone
• RTA 408 Lotion in Healthy VolunteersCompletedPhase 1BiogenNCT02029716Written as RTA 408 Lotion 0.5%, 1%, 3%
• A Study to Find Out How BIIB141 (Omaveloxolone) Moves From the Blood Into the Breastmilk of Healthy Women Who Are Breastfeeding or Pumping MilkCompletedPhase 1BiogenNCT06612879Written as Omaveloxolone

Codes

What other systems call omaveloxolone · ClinicalTrials.gg INT000033

• MeSH (NLM) C000589490omaveloxoloneConfirmed ClinicalTrials.gov, NLM
• UNII (FDA) G69Z98951QOMAVELOXOLONEConfirmed FDA, NLM, Wikidata
• Wikidata Q21098900omaveloxoloneConfirmed FDA, NLM, Wikidata
• NCI Thesaurus C113443OmaveloxoloneOne source FDA
• DrugBank DB12513One source Wikidata

“Confirmed” means two independent publishers link the code to this drug; “one source”, one does and its name agrees.