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CompletedNCT06755177Updated Jan 1, 2025

Clinical Features and Visual Prognosis of Infectious Endophthalmitis

An observational study in Endophthalmitis, sponsored by Zhongnan Hospital. Completed at 1 site in China. Per ClinicalTrials.gov, last updated 2025-01-01.

Sponsored by Zhongnan Hospital · Observational

Study type
Observational
Model
Case-only
Time perspective
Retrospective
Enrollment
100
Sex
All
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Study summary

The aim of this observational study was to retrospectively examine the clinical data of patients with infectious endophthalmitis and to analyse their clinical characteristics.

The main question it aims to answer is: to find the differences between endogenous and exogenous endophthalmitis and to provide new ideas for the diagnosis and treatment of infectious endophthalmitis.

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Conditions studied

  • Endophthalmitis

Keywords

  • Infectious endophthalmitis
  • Endogenous endophthalmitis
  • Exogenous endophthalmitis
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In context

Communicable Diseases

4,452 studies on the registry are indexed under Communicable Diseases; 521 are open to participants now.

This study's enrollment of 100 is below the median of 244 across 1,499 observational studies indexed under Communicable Diseases.

Browse Communicable Diseases studies →

Lead sponsor

Zhongnan Hospital is the lead sponsor of 103 studies on the registry; 48 are open to participants now.

Counted across the registry records on this site, refreshed daily.

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Who can participate

Ages eligible
Child (0–17), Adult (18–64), Older adult (65+)
Sexes eligible
All
Accepts healthy volunteers
No
Sampling method
Non-probability sample

Study population

All inhabitants

Inclusion criteria

  • Patients diagnosed with infectious endophthalmitis by specialist examination. The clinical diagnosis of endophthalmitis was established on the basis of clinical signs and symptoms, including ocular pain, loss of vision, eyelid oedema, conjunctival congestion, inflammation of the anterior chamber (flare-ups, cells, pupillary fibrin membranes, and pus accumulation in the anterior chamber), vitritis, and vitreous clouding on B-scan ultrasound. The diagnosis of infectious endophthalmitis was clarified by the aqueous vitreous pathogen detection test.

Exclusion criteria

Exclusion Criteria:

  • Patients with incomplete medical records; non-infectious uveitis, retinal tumour disease, ocular ischaemia syndrome and other diseases with similar manifestations to endophthalmitis.
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Study design

Observational model
Case-only
Time perspective
Retrospective
Enrollment
100 participants (actual)
Patient registry
No
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What researchers measure

Primary outcomes

  1. visual acuity

    best-corrected visual acuity (BCVA)

    Time frame: Pre-operative, post-operative follow-up at 1 month, 3 months, 1 year, etc.

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Study locations

1 site
  • Zhongnan Hospital of Wuhan University
    Wuhan, Hubei 430071, China
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References and documents

Individual participant data

Plan to share: No

No publications or documents are linked to this record.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on Jan 1, 2025, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
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Registry details

Key details

Study ID
NCT06755177
Lead sponsor
Zhongnan Hospital
Responsible party
Sponsor
First posted
Jan 1, 2025
Start date
Jun 1, 2024
Primary completion
Nov 1, 2024
Completion
Nov 11, 2024
Last update
Jan 1, 2025

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

Not currently enrolling

This study is completed, as verified in Oct 2024. You cannot join it, but the record below documents what was studied.

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Discussion

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