Eisenmenger Complex clinical trials
The registry lists 24 studies for Eisenmenger Complex across more than 10 countries. 5 are recruiting or about to start. Per ClinicalTrials.gov, last updated 2026-05-01.
Status
- Completed
- 13
- Recruiting
- 4
- Status unknown
- 3
- Terminated
- 3
- Not yet recruiting
- 1
Phase
- Phase 3
- 4
- Phase 4
- 4
- Phase 2
- 2
- Early Phase 1
- 1
Where
- Germany
- 7
- United States
- 6
- France
- 4
- Spain
- 3
- Austria
- 3
- United Kingdom
- 3
Who runs them
Actelion (5) · Rigshospitalet, Denmark (2) · Federal University of São Paulo (2) · Competence Network for Congenital Heart Defects (2) · University of California, Los Angeles (2) · Children's Healthcare of Atlanta (1) · Samsung Medical Center (1) · Kazuya Hosokawa (1)
Studies
Recruiting first, then most recently updated. Showing 24 of 24 — search for more.
- Sota-ES - Sotatercept in Patients With Congenital Heart Disease and Eisenmenger´s SyndromeNot yet recruitingNCT07498803Phase 2
- A Study of Sotatercept for Patients With Eisenmenger Syndrome or Unrepaired Shunt-Associated Pulmonary Arterial Hypertension Resistant to Vasodilator TherapyRecruitingNCT07356778Phase 41 country
- COMPERA / COMPERA-KIDSRecruitingNCT013472164 countries
- Pentoxifylline as an Adjunct Therapy for Patients With Eisenmenger SyndromeRecruitingNCT05611268Not applicable1 country
- Respiratory and Physical Therapy in Patients With Associated Pulmonary Arterial Hypertension (APAH) With Congenital Heart DefectsRecruitingNCT01397110Not applicable1 country
- 4DFlow Magnetic Resonance Imaging in Patients With Pulmonary Hypertension Associated With Congenital Heart DiseaseCompletedNCT03928002Not applicable1 country
- Effects of Tracleer (Bosentan) on Pulmonary Arterial Hypertension Related to Eisenmenger PhysiologyCompletedNCT00317486Phase 4
- Eisenmenger Quality Enhancement Research InitiativeCompletedNCT01623492
- Real World Difference After Changing Medication From Nonselective to Selective Endothelin Receptor Antagonist in Stable Eisenmenger SyndromeStatus unknownNCT04732650
- Transcatheter Valve Implantation in Patients With Dysfunctional Left and Right Sided Heart ValvesCompletedNCT02119442Not applicable1 country
- Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger SyndromeTerminatedNCT01739400Phase 319 countries
- Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger SyndromeCompletedNCT01743001Phase 321 countries
- BREATHE 5-OL: Tracleer (Bosentan) in Patients With Pulmonary Arterial Hypertension Related to Eisenmenger PhysiologyCompletedNCT00367770Phase 411 countries
- Six Minutes Walk Test and Shuttle Walk Test in Eisenmenger SyndromeStatus unknownNCT027523991 country
- Effects Oxygen Supplementation Determined Better Exercise Capacity in Eisenmenger SyndromeCompletedNCT02661802Not applicable
- Sleep-disordered Breathing in Eisenmenger SyndromeCompletedNCT02614417
- Iloprost for the Treatment of Pulmonary Hypertension in Adults With Congenital Heart DiseaseTerminatedNCT01319045Not applicable1 country
- Eisenmenger's Syndrome in Adults With CHDCompletedNCT002669031 country
- Exercise Capacity and Quality of Life in Patients With PPH Receiving Short Term Oral L-Citrulline MalateStatus unknownNCT01683981Early Phase 11 country
- Therapy of Pulmonary Arterial Hypertension (PAH) - Treatment With Sildenafil in Eisenmenger PatientsTerminatedNCT00586794Phase 31 country
- The Effects of Inhaled Iloprost on Congenital Heart Disease With Eisenmenger SyndromeCompletedNCT01283958
- Phosphodiesterase-5 Inhibitor in Eisenmenger SyndromeCompletedNCT01200732Phase 21 country
- Bosentan in Treatment of Pulmonary Arterial HypertensionCompletedNCT00266162Phase 41 country
- Combination Treatment With Bosentan and Sildenafil to Patients With Eisenmengers SyndromeCompletedNCT00303004Phase 31 country