Dry Eye Syndromes: all 1,325 studies

Page 4 of 14. Open to participants first (193), then studies with results posted, then the rest; newest registration first within each.

• Evaluation of the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye DiseaseCompletedNCT03920215Phase 2/3Results posted
• A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Clinical Trial of Reproxalap to Assess the Safety and Efficacy in Subjects With Dry Eye DiseaseCompletedNCT03916042Phase 2Results posted
• Study to Evaluate the Safety and Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED)CompletedNCT03889886Phase 2Results posted
• The RENEW Trial: A Multi-Center, Randomized, Double-Masked, Parallel-Group, Vehicle-Controlled, Adaptive Phase 3 Clinical Trial to Assess the Safety and Efficacy of Subjects With Dry Eye DiseaseCompletedNCT03879863Phase 3Results posted
• Efficacy of T2259 in DEDCompletedNCT03874429Not applicableResults posted
• Clinical Trial to Evaluate the Chronic Efficacy of OC-01 Nasal Spray on Signs of Dry Eye Disease (The MYSTIC Study)CompletedNCT03873246Phase 2Results posted
• TearCare System to Treat Dry Eye DiseaseCompletedNCT03857919Not applicableResults posted
• Direct Application of Systane Complete to Contact LensesCompletedNCT03848221Phase 4Results posted
• A Study to Assess Efficacy and Safety of HL036 in Subjects With Dry EyesCompletedNCT03846453Phase 3Results posted
• Efficacy, Safety of T2769 in Dry Eye DiseaseCompletedNCT03830359Not applicableResults posted
• Goblet Cell Degranulation Produced by Intranasal Tear Neurostimulator (ITN) in Dry Eye DiseaseTerminatedNCT03827564Not applicableResults posted
• Pilot Study of TearCare System - Long-Term ExtensionCompletedNCT03804502Not applicableResults posted
• MiBo ThermoFlo Lid Temperature EvaluationTerminatedNCT03787212Not applicableResults posted
• Study of Brimonidine Tartrate Nanoemulsion Eye Drop Solution in the Treatment of Dry Eye Disease (DED)CompletedNCT03785340Phase 3Results posted
• Study of SkQ1 as Treatment for Dry-eye SyndromeCompletedNCT03764735Phase 3Results posted
• TrueTear in Sjogren's Disease PatientsCompletedNCT03719885Not applicableResults posted
• Safety and Tolerability of the Ophthalmic Gel PRO-165 Versus Artelac® Nightime GelCompletedNCT03697876Phase 1Results posted
• Efficacy of OC-01 Nasal Spray on Goblet Cell and Meibomian Gland StimulationCompletedNCT03688802Phase 2Results posted
• Evaluation of Systane Complete for the Treatment of Contact Lens DiscomfortCompletedNCT03682809Phase 4Results posted
• Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic SubjectsCompletedNCT03660475Phase 2Results posted
• Intense Pulse Light Treatment With Meibomian Gland Expression of the Upper Eyelids in Dry Eye DiseaseCompletedNCT03658811Not applicableResults posted
• A Multicenter Study Evaluating AZR-MD-001 in Patients With Meibomian Gland Dysfunction and Evaporative Dry Eye Disease (DED)CompletedNCT03652051Phase 2Results posted
• Evaluation of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye DiseaseCompletedNCT03636061Phase 2Results posted
• Evaluation of the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (the RAINIER Study)CompletedNCT03633461Phase 2Results posted
• The Effect of Manuka Eye Drops on Tear Film PropertiesCompletedNCT03622619Not applicableResults posted
• Safety and Efficacy of KPI-121 in Subjects With DEDCompletedNCT03616899Phase 3Results posted
• A Study to Evaluate AXR-159 Ophthalmic Solution in Patients With Dry Eye DiseaseCompletedNCT03598699Phase 2Results posted
• Ocular Tolerability of Voclosporin Ophthalmic Solution Versus Restasis® in Subjects With Dry Eye DiseaseCompletedNCT03597139Phase 2Results posted
• Study of the TearCare System in Dry Eye DiseaseCompletedNCT03588624Not applicableResults posted
• Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry EyeCompletedNCT03569202Not applicableResults posted
• Treating Contact Lens Discomfort With OrthokeratologyCompletedNCT03566680Not applicableResults posted
• Safety and Tolerability of PRO-087 Versus Xyel Ofteno® and Systane Ultra®, on the Ocular Surface of Healthy SubjectsCompletedNCT03524157Phase 1Results posted
• Safety and Tolerability of the Ophthalmic Gel PRO-167 Versus Corneregel® on Healthy Subjects.CompletedNCT03520348Phase 1Results posted
• Randomized Study of the Safety and Effectiveness of the TearCare System for the Signs and Symptoms of Dry Eye DiseaseTerminatedNCT03502447Not applicableResults posted
• Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study)CompletedNCT03452397Phase 2Results posted
• Dry Eye Disease Study With BrimonidineCompletedNCT03418727Phase 2Results posted
• Tangible Hydra-PEG: A Promising Solution for Scleral Lens Wearers With Dry EyeCompletedNCT03417505Not applicableResults posted
• Topical Fibrinogen-Depleted Human Platelet Lysate in Patients With Dry Eye Secondary to Graft vs. Host DiseaseCompletedNCT03414645Phase 1/2Results posted
• A Multi-Center, Randomized, Double Masked, Parallel-Group, Vehicle-Controlled, Clinical Study to Assess the Safety and Efficacy of Reproxalap Ophthalmic Solution in Subjects With Dry Eye DiseaseCompletedNCT03404115Phase 2Results posted
• Effectiveness of Intense Pulsed Light for Improving Dry Eye SyndromeCompletedNCT03396913Not applicableResults posted
• Tear Lipid Layer Thickness With Emollient Eye DropsCompletedNCT03380624Phase 4Results posted
• A Study to Evaluate the Performance and Safety of CBL-102 Versus Vismed® Multi Eye Drops in the Management of Dry EyeCompletedNCT03368404Not applicableResults posted
• A Study to Assess Efficacy of HL036 in Subjects With Dry EyesCompletedNCT03334539Phase 2Results posted
• Perfluorohexyloctane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)CompletedNCT03333057Phase 2Results posted
• Clinical Trial to Evaluate the Symptoms in Symptomatic Contact Lens Wearers Following Application of Intranasal Tear Neurostimulator Versus ControlCompletedNCT03325673Not applicableResults posted
• CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED)CompletedNCT03292809Phase 2/3Results posted
• Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects With Dry Eye DiseaseCompletedNCT03287635Phase 4Results posted
• Clinical Study to Evaluate Tear Characteristics Following Acute TrueTear™ UseTerminatedNCT03274999Not applicableResults posted
• Effect of IKERVIS® Eye Drops Once Daily on the Quality of Vision in Dry Eye Disease Patients With Severe KeratitisCompletedNCT03237936Phase 4Results posted
• Safety and Efficacy of TrueTear™ for the Treatment of Meibomian Gland DiseaseCompletedNCT03226769Not applicableResults posted
• Efficacy and Safety of the Ophthalmic Solution PRO-087 Versus Systane ® Ultra and Ultra Preservative Free (087LATAMFIV)CompletedNCT03223909Phase 4Results posted
• Optive Brand For Day And Night Dry Eye ManagementCompletedNCT03208673Not applicableResults posted
• Efficacy of IPL Treatment of Dry Eye and Ocular RosaceaCompletedNCT03194698Not applicableResults posted
• A Randomized, Double Masked, Clinical Study of Subjects With Dry Eye SyndromeCompletedNCT03162783Phase 2Results posted
• The Effects of Dietary Supplementation With Omega-3 Fatty Acids on Symptoms of Dry EyeCompletedNCT03141931Not applicableResults posted
• Dry Eye Symptom Relief Assessment With Use of TrueTear in a Controlled Adverse EnvironmentCompletedNCT03097614Not applicableResults posted
• Intense Pulsed Light Study for Dry Eye DiseaseCompletedNCT03089580Not applicableResults posted
• Safety and Efficacy of TOP1630 for Dry Eye SyndromeCompletedNCT03088605Phase 2Results posted
• Safety and Efficacy of BRM421 for Dry Eye SyndromeCompletedNCT03066219Phase 2Results posted
• Tear Film Innovations iLux Safety StudyCompletedNCT03055897Not applicableResults posted
• iLux Treatment for Meibomian Gland Dysfunction (MGD)CompletedNCT03055650Not applicableResults posted
• An 8-week Study to Evaluate Safety and Efficacy of NGF Eye Drops Solution Versus Vehicle in Patients With Dry EyeCompletedNCT03019627Phase 2Results posted
• A Pilot Study of the TearCare System in Adults With Dry Eye DiseaseCompletedNCT03006978Not applicableResults posted
• Symptom Response in Normal and Dry Eye Patients Secondary to Application of a Menthol-Containing Eyedrop (Rohto® Hydra)CompletedNCT02985827Phase 4Results posted
• Study of the Safety and Efficacy of OmegaD Softgels in the Treatment of Dry Eye DiseaseCompletedNCT02980224Phase 3Results posted
• Brimonidine Eye Drops for Treatment of Ocular Graft-vs-Host Disease (oGVHD)TerminatedNCT02975557Phase 1/2Results posted
• A Study to Evaluate the Performance and Safety of CBL-101 Versus Vismed® Multi Eye Drops in the Management of Dry EyeCompletedNCT02975102Not applicableResults posted
• Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2CompletedNCT02974907Phase 3Results posted
• Tear Production by Nasal Neurostimulation Compared to Active ControlCompletedNCT02970799Not applicableResults posted
• Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry EyeTerminatedNCT02965846Phase 3Results posted
• Effects of Gunnar Computer Glasses on Viewing Comfort and PerformanceTerminatedNCT02925884Not applicableResults posted
• Evaluation of Dry Eye Symptoms in CAE With Application of Intranasal NeurostimulationCompletedNCT02910713Not applicableResults posted
• A Two Comparator, Controlled Phase 3 Study in Patients With and Without Evaporative Dry EyeCompletedNCT02871440Phase 3Results posted
• Pilot Study for Investigating the Effect of the Bruder Eye Hydrating Compress on Contact Lens Discomfort in Contact Lens WearersCompletedNCT02848222Not applicableResults posted
• An Open-Label Extension of a Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis SiccaCompletedNCT02845674Phase 3Results posted
• Evaluation of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye DiseaseTerminatedNCT02831387Phase 2Results posted
• Study of the Pharmacodynamic Activity of P-321 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye DiseaseTerminatedNCT02824913Phase 2Results posted
• Safety and Efficacy of KPI-121 Compared to Placebo in Subjects With Dry Eye DiseaseCompletedNCT02819284Phase 3Results posted
• Topical Ophthalmic AGN-195263 for the Treatment of Evaporative Dry EyeTerminatedNCT02815293Phase 3Results posted
• Safety and Efficacy of KPI-121 in Subjects With Dry Eye DiseaseCompletedNCT02813265Phase 3Results posted
• Acute Tear Production Following Single Use of the Oculeve Intranasal NeurostimulatorCompletedNCT02798289Not applicableResults posted
• Clinical Outcomes Following Treatment With SYSTANE® BALANCECompletedNCT02776670Not applicableResults posted
• rhDNase Eye Drops in Patients With Ocular Graft-Vs.-Host DiseaseTerminatedNCT02702518Phase 1/2Results posted
• Can Pregabalin Reduce the Frequency and Severity of Dry Eye Symptoms After Laser-assisted in Situ Keratomileusis?CompletedNCT02701764Phase 2/3Results posted
• Phase 3 Study of OTX-101 in the Treatment of Keratoconjunctivitis SiccaCompletedNCT02688556Phase 3Results posted
• A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye SyndromeCompletedNCT02680158Not applicableResults posted
• CyclASol for the Treatment of Moderate to Severe Dry-eye Disease (DED)CompletedNCT02617667Phase 2Results posted
• Clinical Effects and Safety of 3% Diquafosol After Cataract SurgeryCompletedNCT02608489Not applicableResults posted
• Evaluation of Maintaining Visual Performance in Participants Who Engage in Electronic Visual Tasking While Using Restasis®CompletedNCT02554981Phase 4Results posted
• A Safety and Efficacy Study of a New Eye Drop Formulation in Patients With Dry Eye Disease.CompletedNCT02553772Phase 3Results posted
• Six Month Study to Evaluate the Safety and Effectiveness of the Intranasal Lacrimal NeurostimulatorCompletedNCT02526290Not applicableResults posted
• Clinical Evaluation of Systane® Balance in Dry Eye SubjectsTerminatedNCT02511379Not applicableResults posted
• Tolerability, Safety and Efficacy of Lubricin vs Sodium Hyaluronate Eye Drops in Subjects With Moderate Dry EyeCompletedNCT02510235Not applicableResults posted
• Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dry EyeCompletedNCT02507934Not applicableResults posted
• Evaluation of Clinical Outcomes After the Use of SYSTANE® HYDRATIONCompletedNCT02470429Not applicableResults posted
• OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry EyeCompletedNCT02468700Phase 2Results posted
• A Study to Compare a New Eye Drop Formulation With Systane® Gel Drops and Genteal® Lubricant Gel Drops for Moderate to Severe Dry Eye ReliefCompletedNCT02455050Phase 3Results posted
• Clinical Evaluation Following Use of SYSTANE® ULTRA in the Management of Dry EyeCompletedNCT02446015Not applicableResults posted
• Safety, Efficacy, Tolerability and Pharmacokinetics of AGN-223575 Ophthalmic Suspension in Patients With Dry Eye DiseaseCompletedNCT02435914Phase 2Results posted
• Multicenter Trial Evaluating Quality of Tears Produced by Nasal NeurostimulationCompletedNCT02385292Not applicableResults posted

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