Down Syndrome: all 438 studies
Page 1 of 5. Open to participants first (100), then studies with results posted, then the rest; newest registration first within each.
- Kinematic Analysis of Manual DexterityRecruitingNCT07875127
- An Open-Label Phase II Feasibility Study for the Use of Ublituximab in Adults With Down Syndrome Regression DisorderNot yet recruitingNCT07812181Phase 2
- Hematological Profile in Children With Numerical Chromosomal DisordersNot yet recruitingNCT07807540
- Executive Function Play Opportunities for Children With Down SyndromeNot yet recruitingNCT07792382Not applicable
- Pilot Evaluation of the Developed Syntactic-Semantic Visual Configuration Intervention for Children With Language ImpairmentNot yet recruitingNCT07786545Not applicable
- Effect of Sensory Integration on Gross and Balance on Children With Down SyndromeRecruitingNCT07785011Not applicable
- Vestibular Stimulation Versus Foot Intrinsic Muscle Exercises in Children With Down SyndromeNot yet recruitingNCT07778654Not applicable
- Effects of a Pacifier on Obstructive Sleep Apnea and Its Repercussions in Infants With Down SyndromeNot yet recruitingNCT07658053Not applicable
- The ADVANCE (Assay Development and Validation for Pre-Natal and Obstetric Conditions) Study is the Largest U.S.-Based Prospective Study Demonstrating a Circulating Fetal Cell (CFC) Based Approach to Non-invasive Fetal Risk AssessmentRecruitingNCT07643896
- A Study to Evaluate Mivelsiran in Adult Participants With Early-Stage Down Syndrome-Associated Alzheimer's Disease (DS-AD)RecruitingNCT07636811Phase 2
- Home and Community Use of a Suspension Walker in Pre-Walking Infants With Down SyndromeNot yet recruitingNCT07631130Not applicable
- Vascular Function in Adults With Down SyndromeRecruitingNCT07630207
- Collaboration for Down Syndrome Progress (CDP)RecruitingNCT07625579
- Modulation of the Immune System in Down Syndrome for Improved Outcomes and Neurodevelopment - 1RecruitingNCT07598643Phase 2
- Escalating Doses of Memantine in Down Syndrome (MEDS-123)Not yet recruitingNCT07531940Phase 1
- Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal DisordersRecruitingNCT07493096
- Metric-Optimized Spectacle Prescriptions for Children With Down SyndromeRecruitingNCT07490444Phase 2
- The Neurocognitive Bases of Trust in Intellectual DisabilityRecruitingNCT07434037
- Effects of Jump Rope on Navicular Drop in Down SyndromeRecruitingNCT07428863Not applicable
- Adapting RDAD for DSRecruitingNCT07425769Not applicable
- Rebound Therapy on Ventilatory Functions in Down SyndromeNot yet recruitingNCT07425353Not applicable
- Natural History of Dysregulation and Aging of the Immune System in People With Trisomy 21 With and Without ThymectomyRecruitingNCT07416201
- Qualitative Effects of AEF0217 in Down Syndrome PeopleEnrolling by invitationNCT07413224
- Immune Profile and Respiratory Parameters in Down Syndrome Children With Acute Pneumonia: Pre-Intervention AnalysisRecruitingNCT07366593
- AEF0217 in Participants With Down SyndromeRecruitingNCT07334912Phase 2
- Optimizing the Management of OSA in Children With Down SyndromeRecruitingNCT07334444
- Resilience Training Intervention: Its Effect on Parental Acceptance/Rejection and Burden of Children With Down SyndromeNot yet recruitingNCT07306923Not applicable
- Endotype DIrected Treatment for OSA in Down SyndromeRecruitingNCT07280468Phase 4
- NAD Augmentation to Prevent or Reverse Alzheimer's Disease in People With Down SyndromeNot yet recruitingNCT07278492Phase 1
- Physical Fitness in DS: A Comparison of Cuevas Medak and Rebound ExercisesRecruitingNCT07248449Not applicable
- Effects of Vojta Therapy on Functional Mobility and Gait Parameters in Children With Down SyndromeRecruitingNCT07248267Not applicable
- Effects of Powerball in Children With Down SyndromeRecruitingNCT07244133Not applicable
- Treatment of Atopic Dermatitis and Alopecia Areata With Abrocitinib in Individuals With Down SyndromeRecruitingNCT07242638Phase 2
- Exploring Sympathetic Nervous System Function in Individuals With Down SyndromeRecruitingNCT07238465Phase 3
- LEvetiracetam to Prevent Seizures in Symptomatic Alzheimer's Disease in Adults With Down SyndromeRecruitingNCT07234695Phase 3
- The Efficacy of Therapy in Patients With Acute Myeloid Leukemia and Down Syndrome in RussiaRecruitingNCT07232134Phase 3
- Effects of Chronic Creatine and Beta-Hydroxy-Beta-Methylbutyrate Supplementation on Oxidative Stress, Inflammation, Muscle Strength, and Body Composition in Individuals With Down SyndromeRecruitingNCT07213063Not applicable
- Oro-myofunctional Characteristics and Obstructive Sleep Apnea in Infants With Down SyndromeRecruitingNCT07195253
- Prevalence of Translocation Phenotyping in Children With Down Syndrome and Their ParentsNot yet recruitingNCT07175168
- The Effect of the HEP Approach in Infants With Down SyndromeRecruitingNCT07163780Not applicable
- Drumming Lessons' Influence on Children With Down SyndromeRecruitingNCT07156318Not applicable
- Compassionate Use Study of Epi-ON Corneal Collagen Crosslinking Performed Using UVA Exposure on Eyes With Ectatic Corneal Diseases for Subjects With Down SyndromeRecruitingNCT07135167Phase 3
- Oromyofunctional Therapy: a Rehabilitation Program for OSA in Children With Down Syndrome and Prader-Willi SyndromeRecruitingNCT07122505Not applicable
- Using Technologies to Promote HEalthy Lifestyles in Adolescents With Intellectual DisabilitiesRecruitingNCT07101523Not applicable
- Neuropsychological Evaluation in Intellectual Disability (ENDI)Not yet recruitingNCT07047963
- Non-Invasive Brain Stimulation to Improve Language in Down Syndrome.RecruitingNCT07044804Not applicable
- A VIRTUAL Three-month Intervention Study of the Effects of a Smartphone Application (HippoCamera) on Memory in Teens and Young Adults With Down SyndromeRecruitingNCT07008989Not applicable
- Nutritional Status in Children With Down SyndromeNot yet recruitingNCT06989060
- Effects of Down Dog Yoga on Pre-writing Skills in Children With Down SyndromeRecruitingNCT06977672Not applicable
- Cooking Skills to Improve Long-Term Weight Loss in Young Adults With Intellectual DisabilitiesRecruitingNCT06961591Not applicable
- The Effects Of "Minds In Motion The Maze" on Balance and Gate In Children With Down SyndromeRecruitingNCT06955052Not applicable
- How Simplified Language Affects Comprehension and Learning in Young Children With Down SyndromeRecruitingNCT06951516Not applicable
- Nordic Walk on Balance and Functional Strength in Children With Down SyndromeRecruitingNCT06943508Not applicable
- Effects of Interactive Sensory Play on Manual Dexterity in Down SyndromeNot yet recruitingNCT06943352Not applicable
- Effects of Task-oriented Training on Visual-motor Integration and Upper Limb Function in Children With Down SyndromeNot yet recruitingNCT06943261Not applicable
- Aerobic Exercise With and Without Low Calorie Diet on Adiposity and BMI of Down SyndromeRecruitingNCT06943170Not applicable
- Amyloid Lowering for Alzheimer's in Down's With Donanemab InvestigationNot yet recruitingNCT06911944Phase 4
- Relationship Between Eating Patterns, Body Composition and the Detection of Fatty Liver in Children and Adolescents With Trisomy 21: LiverTy ProjectEnrolling by invitationNCT06888570
- tDCS for Catatonic Depression in Down Syndrome: A Pilot StudyRecruitingNCT06866925Not applicable
- Psychometric Properties of the Turkish Version of the Modified Mini Mental State ExaminationNot yet recruitingNCT06865248
- Pediatric Down Syndrome Post-Approval StudyRecruitingNCT06851338Not applicable
- Shared Book Reading to Promote Mental Well-being Among Young People with and Without Down's SyndromeEnrolling by invitationNCT06813625Not applicable
- Sleep Intervention and Quality of Life in Down SyndromeRecruitingNCT06783725Not applicable
- Effects of High Intensity Interval Training in Down SyndromeRecruitingNCT06777394Not applicable
- Effects of Pelvic Girdle Stabililty With Use of Therapeutic Taping in Down SyndromeRecruitingNCT06770218Not applicable
- Suspension Therapy Effects on Mobility and Balance in Down SyndromeRecruitingNCT06748248Not applicable
- Physical Activity and Community EmPOWERment ProjectRecruitingNCT06740162Not applicable
- Swiss Ball Versus Frenkel Exercises Effects in Down SyndromeRecruitingNCT06732713Not applicable
- Long-term Evaluation of Nasopharyngeal Airway in HypotoniaEnrolling by invitationNCT06614582Not applicable
- Comparison of a Demand Oxygen DeliveryRecruitingNCT06609694Not applicable
- Measuring Aided Language DevelopmentRecruitingNCT06512168Not applicable
- Efficacy of Bumetanide to Improve Cognitive Functions in Down SyndromeRecruitingNCT06465823Phase 2
- Harness-based Mobility Intervention for Infants With Down SyndromeRecruitingNCT06219863Not applicable
- Patterns of Neurodevelopmental DisordersRecruitingNCT06213090
- The Coping With and Caring for Infants With Special Needs Intervention in Down Syndrome InfantsRecruitingNCT06197035Not applicable
- Down Syndrome, Physical Activity and Sleep ApneaRecruitingNCT06061562
- Down Syndrome Obstructive Sleep ApneaRecruitingNCT06043440Phase 2
- Effect of Whole Body Vibration Versus Core Stability Exercises on Balance and Muscle Strength in Children With Down SyndromeRecruitingNCT06036069Not applicable
- Clinical Outcomes From Treatment and Evaluation of Obstructive Sleep Apnoea in Children With Down SyndromeRecruitingNCT06030349
- Brain Outcomes With Lifestyle Change in Down SyndromeRecruitingNCT05985486Not applicable
- Periodontitis and Inflammation in Children With Down Syndrome/Trisomy 21: Study on Biological SamplesRecruitingNCT05970965Not applicable
- Genetic and Epigenetic Variations in Heterokaryotypic Monozygotic Twins Discordant for Down SyndromeRecruitingNCT05767216Not applicable
- Genetic Markers and Biomarkers in Patients With Intellectual Disabilities of Genetic OriginRecruitingNCT05767203Not applicable
- A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute LeukemiaRecruitingNCT05702645
- Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in HypotoniaRecruitingNCT05527652Not applicable
- Treatment of Obstructive Sleep Apnea With Personalized Surgery in Children With Down Syndrome (TOPS-DS)RecruitingNCT05508971Not applicable
- A Study to Assess the Effects of ACI-24.060 in Alzheimer's Disease and in Down Syndrome (ABATE Study)RecruitingNCT05462106Phase 1/2
- Sensitivity of the NIH Toolbox to Stimulant Treatment in Intellectual DisabilitiesEnrolling by invitationNCT05301361Phase 1
- Cholinergic Integrity in Down Syndrome in Association With Aging, Alzheimer's Disease Pathology, and CognitionRecruitingNCT05231798Phase 2
- Gamma Frequency Stimulation in Individuals With Down SyndromeRecruitingNCT05196984Not applicable
- A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)RecruitingNCT04546399Phase 2
- Pulmonary Health in Children With Down SyndromeRecruitingNCT04398862
- GnRH Therapy on Cognition in Down SyndromeRecruitingNCT04390646Phase 2/3
- Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)RecruitingNCT04278404
- Trial-Ready Cohort-Down Syndrome (TRC-DS)RecruitingNCT04165109
- Parent and Infant Inter(X)Action Intervention (PIXI)Enrolling by invitationNCT03836300Not applicable
- Retinal Imaging in Neurodegenerative DiseaseRecruitingNCT03233646
- The Human Trisome ProjectRecruitingNCT02864108
- DS-Connect®: The Down Syndrome RegistryRecruitingNCT01950624
- Specimen Collection From Pregnant Women at Increased Risk for Fetal AneuploidyRecruitingNCT01429389