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RecruitingNCT07156318Updated May 19, 2026

Drumming Lessons' Influence on Children With Down Syndrome

An interventional study of 2 months of drumming lessons given by a professional drummer with extensive experience working with children with Down syndrome and Lessons after measurement in Down Syndrome, sponsored by Vanderbilt University. Recruiting at 1 site in United States. Open to participants aged 7 Years to 15 Years. Per ClinicalTrials.gov, last updated 2026-05-19.

Sponsored by Vanderbilt University · Not applicable, Interventional, and Basic science

From the registry’s dates

  • Started Feb 2026; still recruiting 8 months later.
Phase
Not applicable
Study type
Interventional
Enrollment
30
Allocation
Randomized
Ages
7 Years to 15 Years
Sex
All
01

Study summary

The goal of this clinical trial is to learn if drumming lessons can increase self-control in children with Down syndrome. The main question it aims to answer is whether 2 months of drumming lessons can improve the behavioral control and timing skills in children with Down syndrome. Participants are between 7 and 15 years of age and receive two months of drumming lessons given by a professional drummer with extensive experience working with children with Down syndrome. Children in the experimental group visit our lab once before lessons start and once after lessons are completed. Children in the control group visit our lab twice before they start their lessons. Lab visits include brain recordings taken using a net-style cap, computer tasks, and drumming to music.

Read the detailed description

Down syndrome (DS) is the most common chromosomal cause of cognitive disability, and it affects approximately 1 in 700 live births. Although the genetic etiology of DS (a complete or partial third 21st chromosome) has been known for over 50 years, many fundamental questions about how to support high quality of life for individuals with DS remain unanswered. One area of relative weakness in DS is Inhibitory Control (IC). This skill is important for daily tasks such as following directions, making decisions, and managing money among other tasks. Existing research demonstrates a clear link between playing the drums and IC. In the proposed research, we will conduct an experiment in which 7- to 12-year-old children are randomly assigned to the Experimental (EXP) and Wait List Control (WLC) conditions. In the EXP condition, children will receive drumming lessons between Visit 1 and Visit 2, and in the Wait List Control group, children will receive drumming lessons after Visit 2. In this way, all children will receive drumming lessons, but only the EXP group will show effects of the drumming lessons in Visit 2. Testing conducted during Visits 1 and 2 will include behavioral and neural measures of inhibitory control and drumming, neural measures of beat perception, and parent report of social behavior (via Standardized questionnaire). Our predictions are that children in the EXP condition will show improvements in both measures of IC and increases in precision in the beat perception and drumming tasks. We also expect that parent report of children's behavior on the social skills questionnaire will show improvement. Across the EXP and WLC conditions, we expect no differences at Visit 1 but significant differences between conditions at Visit 2.

02

Conditions studied

  • Down Syndrome

Keywords

  • Children with Down syndrome;
  • Effects of drumming lessons
  • Effects on brain and behavior
  • Inhibitory control
  • Beat perception
  • Intervention study
03

In context

Down Syndrome

438 studies on the registry are indexed under Down Syndrome; 99 are open to participants now.

This study's planned enrollment of 30 is below the median of 37 across 286 interventional studies indexed under Down Syndrome.

Browse Down Syndrome studies →

Lead sponsor

Vanderbilt University is the lead sponsor of 522 studies on the registry; 20 are open to participants now.

Of its 8 completed or terminated interventional studies of FDA-regulated products, 5 (63%) have results posted.

Counted across the registry records on this site, refreshed daily.

04

Who can participate

Ages eligible
7 Years to 15 Years
Sexes eligible
All
Accepts healthy volunteers
No

Go through the criteria one by one — yes, no or not sure — and take the list to your doctor or the study team. Kept in this browser only.

Inclusion criteria

  • Down syndrome

Exclusion criteria

Exclusion Criteria:

  • Already taken drumming lessons
  • Uncorrected hearing loss
  • Uncorrected vision loss
05

Study design

Phase
Not applicable
Primary purpose
Basic science
Allocation
Randomized
Intervention model
Parallel assignment
Masking
None (open label)
Enrollment
30 participants (estimated)

Study arms

  • Experimental
    Experimental group

    Experimental group will receive the drumming lesson intervention between baseline and testing approximately 2 to 3 months later, so the effects of the intervention can be assessed in the lab measures.

    Behavioral: 2 months of drumming lessons given by a professional drummer with extensive experience working with children with Down syndrome

  • Other
    Control group

    Children in the Control condition will receive drumming lessons only after they have completed lab baseline and testing measures, about 2 to 3 months later.

    Behavioral: Lessons after measurement

Interventions

  • Behavioral2 months of drumming lessons given by a professional drummer with extensive experience working with children with Down syndrome

    Drumming lessons consisting of how to use hands to drum on djembe drum, using alternating hands to drum, drumming to a metronome and to music.

  • BehavioralLessons after measurement

    Receiving lessons after the two lab visits should still offer any possible positive effects to participants while still allowing us to compare the Control group children's behaviors to those of the Experimental group.

06

What researchers measure

Primary outcomes

  1. Zoo task

    Behavioral "Go/No go" task done on a computer designed to assess children's inhibitory control

    Time frame: Baseline to two months

  2. Statue task

    Child is encouraged to 'become a statue' by holding their body in a position and not moving

    Time frame: Baseline to two months

  3. Beat Perception

    EEG measure of brain activity during passive listening to music

    Time frame: Baseline to two months

  4. Beat production

    EEG and behavioral measures of when child thinks beat is happening during music or metronome

    Time frame: Baseline to two months

07

Study locations

1 of 1 sites recruiting
08

References and documents

Publications

  • Cahart MS, Amad A, Draper SB, Lowry RG, Marino L, Carey C, Ginestet CE, Smith MS, Williams SCR. The effect of learning to drum on behavior and brain function in autistic adolescents. Proc Natl Acad Sci U S A. 2022 Jun 7;119(23):e2106244119. doi: 10.1073/pnas.2106244119. Epub 2022 May 31. PubMed 35639696 ↗

Individual participant data

Plan to share: No — In this initial investigation, it seems unlikely that data at the participant level would be informative to other researchers. If it becomes clear during the study that sharing of IPD actually would be beneficial, we will recontact participants for their consent to share this information and share those datasets for which we obtain consent.

09

Updates

Tracking since Sep 25, 2026
No changes since tracking began. The registry record was last updated on May 19, 2026, before this site started recording changes on Sep 25, 2026. Its history is on ClinicalTrials.gov ↗
10

Registry details

Key details

Study ID
NCT07156318
Responsible party
Amy Needham (Professor, Vanderbilt University) — Principal investigator
First posted
Sep 5, 2025
Start date
Feb 15, 2026
Primary completion
Jul 2027 (estimated)
Completion
Dec 2027 (estimated)
Last update
May 19, 2026

Study contacts

Amy Needham, PhD
Contact
amy.needham@vanderbilt.edu
16154999992
Caroline Danforth, MS
Contact
caroline.danforth@vanderbilt.edu
(615) 343-1079
Amy Needham, PhD
principal investigator · Vanderbilt University
Miriam Lense, PhD
study director · Vanderbilt University Medical Center

Oversight

Data monitoring committee
No
FDA-regulated drug
No
FDA-regulated device
No
View the source record on ClinicalTrials.gov ↗

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