Depressive Disorder, Major: all 2,805 studies

Page 8 of 29. Open to participants first (565), then studies with results posted, then the rest; newest registration first within each.

• Transcranial Direct Current Stimulation Therapy for Major DepressionCompletedNCT03632434Not applicableResults posted
• Study of Monotherapy Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder (MDD)TerminatedNCT03614156Phase 3Results posted
• A Long Term Study of ALKS 5461 in the Treatment of Refractory Major Depressive Disorder (MDD)TerminatedNCT03610048Phase 3Results posted
• Assessing Symptomatic Clinical Episodes in DepressionCompletedNCT03595579Phase 2Results posted
• Modeling Multi-level Dyadic Behavior to Transform the Science and Practice of Psychotherapy Process and Outcome.CompletedNCT03594773Not applicableResults posted
• Zelquistinel in the Treatment of Major Depressive DisorderCompletedNCT03586427Phase 2Results posted
• Efficacy, Safety, and Tolerability of Levomilnacipran ER in Pediatric Patients (7-17 Years) With Major Depressive DisorderCompletedNCT03569475Phase 3Results posted
• Study of Rapastinel as Monotherapy in Patients With MDDTerminatedNCT03560518Phase 3Results posted
• A Study to Explore the Efficacy of JNJ-67953964 in the Treatment of DepressionCompletedNCT03559192Phase 2Results posted
• A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive DisorderCompletedNCT03538691Phase 3Results posted
• A Neurosteroid Intervention for Menopausal and Perimenopausal DepressionCompletedNCT03505905Phase 1/2Results posted
• A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in VeteransTerminatedNCT03489122Not applicableResults posted
• Individualizing Incentives for Alcohol in the Severely Mentally IllCompletedNCT03481049Not applicableResults posted
• Single Session of tACS in a Depressive EpisodeCompletedNCT03449979Not applicableResults posted
• A Study to Evaluate the Efficacy and Safety of MIN-117 in Adult Patients With Major Depressive DisorderCompletedNCT03446846Phase 2Results posted
• Spinal Cord Stimulation for the Treatment of Major Depressive DisorderCompletedNCT03433339Phase 1/2Results posted
• Psilocybin vs Escitalopram for Major Depressive Disorder: Comparative MechanismsCompletedNCT03429075Phase 2Results posted
• rTMS for MDD: 5.5cm Rule vs. F3 TargetingCompletedNCT03378570Not applicableResults posted
• Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent DepressionCompletedNCT03363919Not applicableResults posted
• Bridge: Proactive Psychiatry Consultation and Case Management for Patients With CancerCompletedNCT03360695Not applicableResults posted
• A Study of Rapastinel for Rapid Treatment of Depression and Suicidality in Major Depressive DisorderTerminatedNCT03352453Phase 2Results posted
• A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant TherapyCompletedNCT03321526Phase 2Results posted
• Adaptive Design Study of NEST sTMS in Subjects With Major Depressive DisorderCompletedNCT03288714Not applicableResults posted
• Inhaled Nitrous Oxide for Treatment-Resistant Depression: Optimizing Dosing StrategiesCompletedNCT03283670Phase 2Results posted
• Transcranial Magnetic Stimulation (TMS) for Motor Symptoms in Psychiatric DisordersCompletedNCT03275766Not applicableResults posted
• A Study to Evaluate the Efficacy and Safety of JNJ-42847922 as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant TherapyCompletedNCT03227224Phase 2Results posted
• Melancholic Depression and Insomnia as Predictors of Response to Quetiapine in Patients With Major DepressionCompletedNCT03207438Phase 4Results posted
• BTRX-246040 Administered Once Daily to Patients With Major Depressive DisorderCompletedNCT03193398Phase 2Results posted
• A Study of ALKS 5461 for Treatment Refractory Major Depressive Disorder (MDD)CompletedNCT03188185Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for SuicideCompletedNCT03185819Phase 2Results posted
• Effects of Psilocybin in Major Depressive DisorderCompletedNCT03181529Phase 2Results posted
• Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy ResponseCompletedNCT03175068Not applicableResults posted
• The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression.CompletedNCT03156504Phase 4Results posted
• Salicylic Augmentation in DepressionTerminatedNCT03152409Phase 2Results posted
• Lipopolysaccharide (LPS) Challenge in DepressionCompletedNCT03142919Phase 1Results posted
• Neural Mechanisms of Monoaminergic Engagement in Late-life Depression Treatment Response (NEMO)CompletedNCT03128021Phase 4Results posted
• Accelerated TMS to a Novel Brain Target in MDD and PTSDCompletedNCT03114891Not applicableResults posted
• ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)CompletedNCT03113968Phase 2/3Results posted
• 54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for SuicideCompletedNCT03097133Phase 3Results posted
• Novel Neural Circuit Biomarkers of Major Depression Response to CCBTCompletedNCT03096886Not applicableResults posted
• A Study to Evaluate the Safety and Efficacy of TS-121 as an Adjunctive Treatment for Major Depressive DisorderTerminatedNCT03093025Phase 2Results posted
• Rapid Antidepressant Effects of LeucineTerminatedNCT03079297Phase 2Results posted
• Cognitive and Mood Assessment Data in Major Depressive Disorder Using Digital Wearable TechnologyCompletedNCT03067506Results posted
• Effectiveness of a Mobile Texting Intervention for People With Serious Mental IllnessCompletedNCT03062267Not applicableResults posted
• THINC-it Vortioxetine - Sensitivity to ChangeCompletedNCT03053362Phase 2/3Results posted
• Safety, Tolerability, PK Profile, and Symptom Response of a 7-Day Dosing With 25 mg or 50 mg Daily of REL-1017 in MDDCompletedNCT03051256Phase 2Results posted
• 54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for SuicideCompletedNCT03039192Phase 3Results posted
• Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Major Depressive Disorder (CLARITY)CompletedNCT03018340Phase 2Results posted
• Long-term Safety Study of Rapastinel as Adjunctive Therapy in Patients With Major Depressive DisorderCompletedNCT03002077Phase 3Results posted
• A Study to Evaluate SAGE-217 in Participants With Moderate to Severe Major Depressive DisorderCompletedNCT03000530Phase 2Results posted
• ECT Pulse Amplitude and Medial Temporal Lobe EngagementCompletedNCT02999269Phase 4Results posted
• Stepped Care for Depression in Heart FailureCompletedNCT02997865Not applicableResults posted
• Goal Achievement After a Change to Vortioxetine in Adults With Major Depressive DisorderCompletedNCT02972632Phase 4Results posted
• Optimizing Outcomes of Treatment-Resistant Depression in Older AdultsCompletedNCT02960763Phase 4Results posted
• Transcranial Laser Therapy, Continuous and Pulsed Light, for Major Depressive Disorder (ELATED-3)CompletedNCT02959307Not applicableResults posted
• A Study of Rapastinel as Adjunctive Therapy in the Prevention of Relapse in Patients With Major Depressive DisorderCompletedNCT02951988Phase 3Results posted
• A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-03)CompletedNCT02943577Phase 3Results posted
• A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-02)CompletedNCT02943564Phase 3Results posted
• Flavanol Augmentation for Antidepressant Non-Responsive Late Life DepressionTerminatedNCT02943096Not applicableResults posted
• TMS for Adults With Autism and DepressionCompletedNCT02939560Not applicableResults posted
• A Study of Rapastinel as Adjunctive Therapy in Major Depressive Disorder (RAP-MD-01)CompletedNCT02932943Phase 3Results posted
• Placebo-controlled Trial of 5-hydroxytryptophan and Creatine for SSRI or SNRI Augmentation in Treatment Resistant Depression in FemalesTerminatedNCT02922725Phase 4Results posted
• Cost- Effectiveness and Quality of Life Assessment in Major Depression DisorderCompletedNCT02901249Phase 4Results posted
• Augmentation of Treatment-Resistant Depression With An Analog of the Neuroactive Steroid AllopregnanoloneCompletedNCT02900092Not applicableResults posted
• The UTHealth Ketamine ProjectTerminatedNCT02882711Phase 2Results posted
• Long-term, Open-label, Flexible-dose, Extension Study of Vortioxetine in Child and Adolescent Participants With Major Depressive Disorder (MDD) From 7 to 18 Years of AgeTerminatedNCT02871297Phase 3Results posted
• Integrated Smoking Cessation Treatment for Smokers With Serious Mental IllnessCompletedNCT02845440Not applicableResults posted
• NeoSync TMS Treatment for Bipolar I DepressionTerminatedNCT02839798Phase 2Results posted
• Depressed Mood Improvement Through Nicotine Dosing (Depressed MIND Study)CompletedNCT02816138Phase 4Results posted
• Lifestyle Intervention for Young Adults With Serious Mental IllnessCompletedNCT02815813Not applicableResults posted
• Treating Caregiver Depression to Improve Childhood Asthma: Impact and MediatorsCompletedNCT02809677Not applicableResults posted
• Treatment of Depression With Connectivity Guided Robotically Delivered rTMSTerminatedNCT02802293Not applicableResults posted
• The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive DisorderCompletedNCT02749721Phase 4Results posted
• A Study of L-DOPA for Depression and Slowing in Older AdultsCompletedNCT02744391Phase 4Results posted
• Supportive and Supportive-Expressive Treatment for DepressionCompletedNCT02728557Not applicableResults posted
• Exploratory Trial to Assess the Functionality of an Integrated Call Center for the Digital Medicine SystemCompletedNCT02722967Phase 2Results posted
• Levomilnacipran ER vs. Adjunctive Quetiapine for Adults With Inadequate Relief With SSRIs in MDDCompletedNCT02720198Phase 3Results posted
• Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Patients Aged 12 to 17 Years With Major Depressive Disorder (MDD)CompletedNCT02709746Phase 3Results posted
• Active Reference (Fluoxetine) Fixed-dose Study of Vortioxetine in Paediatric Participants Aged 7 to 11 Years With Major Depressive Disorder (MDD)CompletedNCT02709655Phase 3Results posted
• Effects of Amygdala Neurofeedback on Depressive SymptomsTerminatedNCT02709161Not applicableResults posted
• Study of Neural Responses Induced by Antidepressant EffectsCompletedNCT02674529Phase 2/3Results posted
• The Exploratory Study to Investigate the Effect of Ramelteon for Insomnia Patients With Major Depressive Disorder by Using ActigraphyCompletedNCT02669082Phase 4Results posted
• Tapering Off AntidepressantsTerminatedNCT02661828Not applicableResults posted
• Ketamine for Relapse Prevention in Recurrent Depressive DisorderTerminatedNCT02661061Phase 1Results posted
• Tocilizumab Augmentation in Treatment-Refractory Major Depressive DisorderTerminatedNCT02660528Phase 2Results posted
• Treatment of Young Adults With Comorbid AUD/MDD: A Pilot Medication TrialCompletedNCT02646449Phase 2Results posted
• Genecept Assay™ vs. Treatment-as-Usual to Evaluate Efficacy of Assay-Guided Treatment in Adults With MDDCompletedNCT02634177Not applicableResults posted
• Hyperthermic Yoga for Depressive SymptomsCompletedNCT02607514Not applicableResults posted
• Safety and Effectiveness of NeuroStar® Transcranial Magnetic Stimulation (TMS) Therapy in Depressed AdolescentsCompletedNCT02586688Not applicableResults posted
• Ketamine Infusion for Adolescent Depression and AnxietyCompletedNCT02579928Phase 4Results posted
• Adjunctive Treatment of Major Depression Utilizing Auricular AcupunctureCompletedNCT02579343Not applicableResults posted
• Omega-3 Fatty Acids for Major Depressive Disorder With High Inflammation: A Personalized ApproachCompletedNCT02553915Phase 2/3Results posted
• Korean Post Marketing Surveillance to Observe Effectiveness and Safety of PRISTIQCompletedNCT02548949Results posted
• Ketamine for Depression: An MRI StudyCompletedNCT02544607Phase 4Results posted
• Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant DepressionCompletedNCT02522377Not applicableResults posted
• Sleep-Disordered Breathing and PAP in Perinatal DepressionCompletedNCT02507297Not applicableResults posted
• Study of Ibuprofen Effects on Brain FunctionCompletedNCT02507219Phase 2/3Results posted
• An Efficacy, Safety and Tolerability Study of JNJ-42165279 in Participants With Major Depressive Disorder With Anxious DistressCompletedNCT02498392Phase 2Results posted
• Antidepressant Effects of the Glycine Receptor Antagonist AV-101 (4-chlorokynurenine) in Major Depressive DisorderCompletedNCT02484456Phase 2Results posted
• The Serotonin Transporter Availability for Prognosing Major Depressive Disorder (MDD) Treatment and Detecting MDDCompletedNCT02473783Phase 2Results posted

← Depressive Disorder, Major overview