Depressive Disorder, Major: all 2,805 studies
Page 4 of 29. Open to participants first (565), then studies with results posted, then the rest; newest registration first within each.
- Intravenous Ketamine for Treatment-Resistant DepressionRecruitingNCT06668571Phase 2
- Effects of Low-intensity Transcranial Magnetic Stimulation on Major Depressive Disorder, and on 5-hydroxyindoleacetic Acid and Brain-derived Neurotrophic Factor LevelsRecruitingNCT06667180Phase 1/2
- Lithium for Prevention of Cognitive Declining in Mood IllnessesNot yet recruitingNCT06662526Phase 4
- Treating Loneliness In The Older Adult With Depression With tDCSRecruitingNCT06658795Not applicable
- Effective of Transcranial Magnetic Stimulation (TMS) vs Treatment as Usual for First-Episode Depression in AdultsNot yet recruitingNCT06644833Phase 4
- Combined Effect of TCC-I and BATD on Depressive Symptoms and InsomniaEnrolling by invitationNCT06633263Not applicable
- Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)RecruitingNCT06633016Phase 2
- Measuring Psychomotor Response to L-DOPA Challenge As a Biomarker for Outcomes in Late-Life Depression: a Pilot Feasibility TrialRecruitingNCT06626152Phase 2
- The Effect of Mediterranean Diet and Mindfulness Eating on Depression Severity in People With Obesity and Major Depressive DisorderRecruitingNCT06621394Not applicable
- Ovarian Hormone Withdrawal, Anhedonia, and Reward Sensitivity in Women With Premenstrual Exacerbations of DepressionRecruitingNCT06610305Phase 4
- Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)Enrolling by invitationNCT06605105Phase 3
- Evaluation of the Concordance Between Measures Obtained by a Medical Device for Emotional Monitoring (EMOCARE) and the Patient Health Questionnaire (PHQ-9) Score in Patients With Mild to Severe Depressive EpisodeRecruitingNCT06601140Not applicable
- Psilocybin With Pimavanserin Compared to Psilocybin Alone for the Treatment of Major Depressive DisorderRecruitingNCT06592833Phase 2
- Psychiatric Multi-omics and Neuroimaging ProjectRecruitingNCT06580860
- Leucine in Midlife DepressionRecruitingNCT06580145Phase 2
- Precision Care for Major Depressive DisorderEnrolling by invitationNCT06580041Phase 4
- Ketamine-Assisted Psychotherapy (KAP) Compared to Ketamine Alone for the Treatment of DepressionRecruitingNCT06559826Phase 2
- Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia SymptomsRecruitingNCT06559306Phase 3
- Sensory Synchronized Imaging and NeuromodulationNot yet recruitingNCT06548113Not applicable
- Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive DisorderRecruitingNCT06547489Phase 2
- bWell-D Pilot Randomized Controlled TrialRecruitingNCT06546917Not applicable
- Effects of rTMS Compared to SSRI as Early Treatment of Depression (Early-TMS)Not yet recruitingNCT06545474Not applicable
- Identifying Local Field Potential Biomarkers for Treatment-Resistant Major Depression With Deep Brain StimulationRecruitingNCT06542094Not applicable
- Comorbid Obesity and Depression With an Anti-inflammatory MedicationRecruitingNCT06537921Not applicable
- Study of Electrophysiological Markers of Antidepressants in Major Depressive DisorderNot yet recruitingNCT06532604Not applicable
- Low Amplitude Pulse Seizure Therapy Versus Standard Ultra-Brief Right Unilateral Electroconvulsive TherapyRecruitingNCT06529029Phase 2/3
- Comparing the Efficacy of Accelerated vs. Standard fMRI-guided iTBS in Treating Adolescents DepressionRecruitingNCT06528938Not applicable
- A Study to Assess the Efficacy, Safety and Tolerability of VLS-01 Buccal Film, Compared to Placebo in Patients With Treatment Resistant Depression (ELUMINA)RecruitingNCT06524830Phase 2
- Accelerated Intermittent Theta Burst in Treatment-Naive AdolescentsRecruitingNCT06523439Not applicable
- A Biological Signature for the Early Differential Diagnosis of PsychosisNot yet recruitingNCT06515522
- Operation of Brain Stimulation Equipment Under Remote Viewing Effectiveness RegistryEnrolling by invitationNCT06512324
- Investigation of the Antidepressant Effects of (2R,6R)-HNK, an Enhancer of Synaptic Glutamate Release, in Treatment-Resistant DepressionRecruitingNCT06511908Phase 2
- Evaluation of the Impact of the EDIT-B® Blood Test on the Health Status of Patients Presenting a Major Depressive Episode. Clinical Utility and Medico-Economic AspectsRecruitingNCT06507787Not applicable
- Gamma Oscillations as a Prognostic Marker for Ketamine Therapy in Treatment Resistant DepressionRecruitingNCT06480201Phase 1
- Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)Not yet recruitingNCT06470035Not applicable
- Psychoeducational Group for DepressionRecruitingNCT06467474Not applicable
- Natural History of Depression, Bipolar Disorder and Suicide RiskRecruitingNCT06462196
- Amygdala MRI-TIS for DepressionRecruitingNCT06461260Not applicable
- Improving Treatment of Major Depressive Disorder by Reducing Negative Future-Oriented Mental ImageryRecruitingNCT06454695Not applicable
- Amygdala and dLPFC MRI-TIS for Depression in AdolescentsRecruitingNCT06452849Not applicable
- PET Biomarker Study for Antidepressant Response Prediction in Major Depressive DisorderNot yet recruitingNCT06452290Not applicable
- Cerebral and Anti-inflammatory Response Through Exercise - Mechanisms In Depressive DisordersRecruitingNCT06450704Not applicable
- Efficacy and Safety of Low-dose Laser Acupuncture on Treating Insomnia Associated With Major Depressive DisorderNot yet recruitingNCT06443242Not applicable
- Sleep Modulation to Treat DepressionRecruitingNCT06443216Not applicable
- Cultural Adaptation of EMDR for Major Depressive Disorder and Compaire Its Online and Face-to-Face TestingRecruitingNCT06439043Not applicable
- To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release TabletsNot yet recruitingNCT06426485Phase 4
- Treatment ResistAnt Depression Subcallosal CingulatE Network DBS (TRANSCEND)RecruitingNCT06423430Not applicable
- The Effect of Mindfulness-Based PsychoeducationRecruitingNCT06417619Not applicable
- Non-invasive BCI and Application Verification for Depressed PeopleRecruitingNCT06417437Phase 4
- Pharmacologic Treatment Augmentation in Chronic DepressionRecruitingNCT06410599Phase 2
- Effectiveness of MST Versus ECT for Major Depressive EpisodeRecruitingNCT06409325Not applicable
- Physical Activity Program for TRDRecruitingNCT06404320Not applicable
- Imaging Depression in Parkinson's DiseaseRecruitingNCT06402955Phase 2
- The Effects of Exercise on Gut Bacteria, Mood and Cognition in DepressionRecruitingNCT06398496Not applicable
- Deep Phenotyping for Clinical Inferring Response in Treatment Resistant DepressionRecruitingNCT06396312
- Clinical, Cognitive and Neural Effects of Potentiation of ECT by rTMS in Treatment-Resistant DepressionNot yet recruitingNCT06391723Not applicable
- Adolescent Interpersonal Counseling in Primary CareRecruitingNCT06390462
- Non-invasive Vagus Nerve Stimulation as a Tool to Modulate Stomach-Brain Coupling in DepressionEnrolling by invitationNCT06389175Not applicable
- Electroencephalography-based Precise Repetitive Transcranial Magnetic Stimulation TreatmentRecruitingNCT06385405Not applicable
- The Friendship Bench Plus TrialRecruitingNCT06384209Not applicable
- Search for Novel Transcranial Magnetic Stimulation (TMS) Targets for Mental IllnessRecruitingNCT06376734Phase 2
- pBFS-guided rTMS Over DMPFC for Treatment-Resistant DepressionRecruitingNCT06350396Not applicable
- Regulation of Affect and Physiology in DepressionRecruitingNCT06345859Phase 2
- Acceptability and Feasibility of Transcranial Magnetic Stimulation (TMS) for Depression in Multiple SclerosisRecruitingNCT06329414
- Whole-body Hyperthermia for DepressionRecruitingNCT06323785Not applicable
- Effectiveness of an Ecological Momentary Emotion Regulation InterventionRecruitingNCT06311136Not applicable
- Immune Activation, Neural Plasticity and DepressionRecruitingNCT06306248
- Inflammatory Control of Antidepressant Efficacy: a Pharmaco-epigenetic ApproachRecruitingNCT06306209
- Tizanidine vs. Zolpidem in Primary Insomnia: A Randomized TrialNot yet recruitingNCT06303076Phase 4
- Cognitive Dysfunction in the Addictions Study - Project 4 (P4)RecruitingNCT06299787Not applicable
- Application of the Web-based Acceptance and Commitment Therapy for DepressionRecruitingNCT06293781Not applicable
- Using TMS to Understand Neural Processes of Social MotivationRecruitingNCT06274112Not applicable
- The Relationship Between Emotion Regulation and Psychiatric Disorder in YouthRecruitingNCT06271954
- pBFS Guided rTMS Over Different Targets for Treatment-Resistant DepressionNot yet recruitingNCT06255561Not applicable
- The Effects of Psilocybin on Self-Focus and Self-Related Processing in Major Depressive DisorderRecruitingNCT06247839Phase 3
- Impact of Psychomotor Therapy on the Quality of Life in DepressionRecruitingNCT06234176Not applicable
- Stress Management in Depressive Disorder: Resilience Training vs. Yoga: Biological, Epigenetic, and Brain CorrelatesNot yet recruitingNCT06229652Not applicable
- Ketamine Treatment for PTSD and MDD in TBINot yet recruitingNCT06228391Phase 2
- A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive SymptomsRecruitingNCT06223880Phase 4
- Neural Circuit Effects of Ketamine in DepressionRecruitingNCT06213324Phase 4
- Transcranial Alternating Current Stimulation (tACS) on Serotonin-1A Receptor in DepressionRecruitingNCT06211140Not applicable
- The Relations Among Endotoxin, Inflammatory Cytokines, Cognitive Markers and Brain MRI Changes in Subjects With Depressive DisorderRecruitingNCT06203015
- Self-Identification ProgramRecruitingNCT06183359Not applicable
- Virtual Reality Reward Training and Transcranial Magnetic Stimulation for DepressionRecruitingNCT06178731Not applicable
- Feasibility of Conducting a Clinical Trial Assessing Efficacy of Lactate as Adjunctive Therapy in Patients With Major Depressive DisorderNot yet recruitingNCT06168175Phase 2
- Integrins and Protocadherins in Glutamatergic Circuits: Identification of Common Signaling Pathways and Molecular Targets in Anxiety and Major Depressive Disorders (GAPsy)RecruitingNCT06167590Not applicable
- The Impact of Working Memory and Reward Markers on DLPFC Activity in Treatment-resistant DepressionRecruitingNCT06163625Not applicable
- Effect of Suicidality on Social CognitionRecruitingNCT06163612
- Comparing the Efficacy of fMRI-Guided vs. Standard iTBS in Treating DepressionRecruitingNCT06152705Not applicable
- Cognitive Dysfunction and Inflammation in Depression: Experimental Inhibition Via InfliximabRecruitingNCT06136546Phase 2
- Causal Role of Delta-beta Coupling for Goal-directed Behavior in Anhedonic DepressionRecruitingNCT06132581Not applicable
- Psilocybin rTMS for Treatment Resistant DepressionRecruitingNCT06132178Phase 2
- The Role of Negr1 In Modulating Neuroplasticity in Major Depression (RONIN)RecruitingNCT06131268Phase 4
- RESISTance Exercise for Depression TrialRecruitingNCT06110897Not applicable
- Ketogenic Diet for DepressionNot yet recruitingNCT06105762Not applicable
- Positioning of Esketamine Treatment in the Real-world Management of DepressionRecruitingNCT06103760Phase 4
- rTMS Therapy for Treatment-Resistant Depression With Different Targets Guided by pBFSRecruitingNCT06095778Not applicable
- Positive Processes and Transition to Health (PATH)RecruitingNCT06093906Not applicable
- Presynaptic Imaging in Major Depressive Episodes After COVID-19RecruitingNCT06086366
- Relevance of a Telemedicine Monitoring in the Management of DepressionRecruitingNCT06076317Not applicable