Depressive Disorder, Major: all 2,805 studies
Page 2 of 29. Open to participants first (565), then studies with results posted, then the rest; newest registration first within each.
- Neural Correlates of Suicidal Behavior in YouthNot yet recruitingNCT07568054Not applicable
- Inhaled DMT for Major Depressive DisorderRecruitingNCT07562191Phase 2
- Synaptic Mechanisms of Continuous Theta Burst Stimulation in DepressionRecruitingNCT07560878Early Phase 1
- Efficacy and Safety of Daridorexant in Patients With Major Depressive Disorder and InsomniaNot yet recruitingNCT07555743Phase 4
- TIS for NSSI in Adolescent DepressionRecruitingNCT07554755Not applicable
- MOCHA: Embedded Inpatient Mental Health Care for High-Risk Perinatal PatientsRecruitingNCT07540585
- Efficacy and Safety of Sertraline Combined With Lactobacillus Crispatus in Adolescents With DepressionRecruitingNCT07539805Phase 2
- Venous Tourniquet vs. Arterial Tourniquet for Seizure Monitoring in ECTRecruitingNCT07534475Not applicable
- Investigating Functional Changes in the Frontotemporal Cortex of Patients With Major Depressive Disorder Following Electroconvulsive Therapy or Magnetic Seizure Therapy Using Functional Near-infrared Spectroscopy (fNIRS)RecruitingNCT07533773Not applicable
- Efficacy and Safety of a Theta Burst Stimulation Protocol of Repetitive Transcranial Magnetic Stimulation in Treatment-Resistant DepressionNot yet recruitingNCT07529574Not applicable
- Early Brainwave Biomarkers for Personalized Neuromodulation in Treatment-resistant DepressionNot yet recruitingNCT07528157Not applicable
- ATLAS-1: Advanced Trial for Longitudinal Assessment in Salma 1RecruitingNCT07528014
- Dextromethorphan-Bupropion on Striatal Activity in Adults With Major Depressive DisorderRecruitingNCT07523048Phase 2
- Mindfulness Engaged Neurostimulation for Depression (MEND II)RecruitingNCT07512284Phase 2
- Home tDCS for the Treatment of Major Depression.RecruitingNCT07510880Not applicable
- Efficacy of Bright Light Therapy on Cognitive Impairment in Major Depressive Disorder and Its Neuroimaging Mechanisms: Protocol for a Randomised Controlled TrialRecruitingNCT07508215Not applicable
- CARED : A Novel Rapid Treatment Paradigm for DepressionRecruitingNCT07507370Not applicable
- Functional Magnetic Resonance Imaging Study of Inhibitory Control in Bipolar Disorder and Major Depressive DisorderNot yet recruitingNCT07503275Not applicable
- Shortened LSD Intervention for Major Depressive DisorderNot yet recruitingNCT07503002Phase 1
- Neutralizing Interleukin (IL)-6RecruitingNCT07493317Phase 2
- Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using SolriamfetolRecruitingNCT07484217Phase 3
- Pharmacogenetic-Guided Antidepressant Treatment in DepressionNot yet recruitingNCT07480486Not applicable
- Biomarker Research on Ultra-High-Field MRI Combined With Visual Perception Assessment in the Diagnosis and Treatment Outcomes of Severe Mental DisordersRecruitingNCT07479758
- Study of Psilocybin Under Anesthesia Controlled by EEGNot yet recruitingNCT07479550Phase 2
- ipRGC as a Potential Biomarker for Predicting Transcranial Magnetic Stimulation Treatment Response in Major Depressive DisorderRecruitingNCT07474974Not applicable
- Gender Differences in Depression Severity, Gender-Sensitive Symptoms, Resilience, and Stigma in Major Depressive DisorderRecruitingNCT07474363
- Multimodal Clinical Study of Electroconvulsive Therapy and Magnetic Seizure TherapyRecruitingNCT07473648Not applicable
- Causal Role of Rostromedial Prefrontal Cortex for Positive Savoring in DepressionEnrolling by invitationNCT07467473Not applicable
- Lifestyle Interventions to Prevent cOgnitive Deficits in Subjects With Depressive Symptoms: From mEchanisms to Clinical pRacticeRecruitingNCT07462013Not applicable
- Brain Network Mechanisms of Cognitive Impairments in Major Psychiatric Disorders and Their Clinical ApplicationsNot yet recruitingNCT07444463Not applicable
- Accelerated Treatment of Depressive Patients With tDCSRecruitingNCT07444242Not applicable
- Psychobiological Markers to Improve Diagnosis and to Predict Affective Episodes in Bipolar DisorderNot yet recruitingNCT07427966
- Virtual Reality-Based Mindfulness as an Adjunct to Treatment as Usual in Treatment-Resistant DepressionRecruitingNCT07422519Not applicable
- Interest of Adaptated Physical Activity (APA) on the K Recovery Constant, Reflecting the Rate of Muscle Oxygenation Recovery in Menopausal Women Suffering From DepressionNot yet recruitingNCT07417709Not applicable
- A Study of Brenipatide in Adult Participants With Major Depressive DisorderRecruitingNCT07412756Phase 3
- Psilocybin-assisted Therapy for Comorbid Major Depressive Disorder and Alcohol Use DisorderNot yet recruitingNCT07405606Phase 2
- VR Pupillometry in Cognitive ImpairmentRecruitingNCT07402356
- Mitochondrial Function After KetamineNot yet recruitingNCT07399756
- Intradermal Acupuncture as an Adjunct to SSRI Tapering in Major Depressive DisorderNot yet recruitingNCT07390981Not applicable
- A Longitudinal Follow-Up Study on Predicting Major Depressive Disorder From Rest-Activity Rhythm ProfilesNot yet recruitingNCT07388849
- Group Therapy for Major Depression: Comparing Expectation-Focused and Reward-Focused Psychotherapy ApproachesRecruitingNCT07388004Not applicable
- Modular Intervention for Depression StudyRecruitingNCT07380451Not applicable
- Real-world Clinical Response to Trazodone in Italy, Poland, and RomaniaRecruitingNCT07377682
- Ketogenic Diet and Neuromodulation in Treatment Resistant DepressionNot yet recruitingNCT07376018Not applicable
- To Evaluate the Safety, Tolerability, Pharmacokinetic Characteristics and Food Effects of LY03021 in Healthy Chinese SubjectsEnrolling by invitationNCT07371065Phase 1
- Mindfulness Training During Accelerated TMS for DepressionRecruitingNCT07369557Not applicable
- NQ Square TMS for MDD 1Dx3S Adults Multi-site Sham-controlled ProtocolEnrolling by invitationNCT07369180Not applicable
- Gaze Contingent Attentional Reinforcement in Major Depressive DisorderNot yet recruitingNCT07364981Not applicable
- Salivary Oxytocin as a Biomarker of Psychedelic TreatmentEnrolling by invitationNCT07345858
- First-In-Human (FIH), Single Ascending Dose (SAD) Study and Multiple Ascending Dose (MAD) Study of SP-101 InjectionNot yet recruitingNCT07334249Phase 1
- Neurobiological and Genomic Predictors of Relapse in DepressionRecruitingNCT07328373
- Electroconvulsive Therapy Augmented With Transcranial Magnetic Stimulation for Treatment Resistant DepressionRecruitingNCT07324070Not applicable
- Group Intervention for Romantic Relationships in Young Adults With Severe Mental IllnessRecruitingNCT07316803Not applicable
- Retrospective Observational Study of Blood-based Biomarkers in the Diagnosis and Monitoring of Patients With a Neurodegenerative Disease or Mental DisorderEnrolling by invitationNCT07314190
- Cohort Study on Medical Students' Mental HealthRecruitingNCT07305701
- A Study to Evaluate the Effectiveness of DT-101 in Patients With DepressionRecruitingNCT07300969Phase 2
- ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant ResponseRecruitingNCT07284667Phase 2
- Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive DisorderRecruitingNCT07282678Not applicable
- REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic ToolRecruitingNCT07280065Phase 3
- A Study to Assess Change in Disease Activity and Adverse Events of Oral Icalcaprant in Adult Participants With Major Depressive DisorderRecruitingNCT07276997Phase 2
- Improving Treatment for Depression in General Practice Using a Step-by-Step Care Plan.RecruitingNCT07263321Not applicable
- Sustained Mood Improvement With Laughing Gas ExposureNot yet recruitingNCT07262008Phase 3
- Escitalopram Plasma Concentrations in Premenopausal and Postmenopausal WomenNot yet recruitingNCT07259525
- Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL)Not yet recruitingNCT07247370Phase 1/2
- Multimodal Phenotyping in Adolescent Inpatient Depression: An Observational StudyRecruitingNCT07247344
- Optimizing Brain Excitability in DepressionRecruitingNCT07242105Not applicable
- Prospective Observational Study of the Relationship Between Sociodemographic Factors, Blood-based Biomarkers and Psychiatric Symptoms in Neurodegenerative Diseases and Mental DisordersEnrolling by invitationNCT07239843
- Understanding Mechanisms of Synaptic Degeneration Underlying Clinical Symptoms in Patients With MDs and NDs.Enrolling by invitationNCT07234851
- Mechanisms Of Orbitofrontal Stimulation in DepressionRecruitingNCT07230990Not applicable
- Home-Based Transcranial Direct Current Stimulation In Major Depressive Disorder (HOME)RecruitingNCT07228468Not applicable
- A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive DisorderRecruitingNCT07227454Phase 3
- Double-blind, Placebo-controlled Study in Adults With Major Depressive DisorderRecruitingNCT07226661Phase 2
- Psilocybin Intervention for Veterans Overcoming Treatment-Resistant DepressionRecruitingNCT07226232Phase 3
- Therapy and Tech StudyNot yet recruitingNCT07225192Not applicable
- Exercise-priming of CBT for Depression: the CBT+ TrialRecruitingNCT07221929Not applicable
- Peer-Delivered Behavioral Activation in a CCBHCRecruitingNCT07219394Not applicable
- Improving Outcomes in Adolescent Inpatient Depression With Deep Transcranial Magnetic StimulationRecruitingNCT07217444Not applicable
- Spaced Transcranial Direct Current Stimulation for Treatment-Resistant Depression: A Home-Based Feasibility and Safety StudyRecruitingNCT07217223Not applicable
- Accelerated Neuromodulation of Anterior Cingulate Cortex for DepressionRecruitingNCT07212465Not applicable
- A Study of Vortioxetine in Japanese Pediatric Patients With Major Depressive DisorderRecruitingNCT07204314Phase 3
- tVNS, Motivation, and Insulin SensitivityRecruitingNCT07198100Not applicable
- IMPACT-D+: Immune-Modulating and Psychometric Effects of Accelerated TMS in Depression Plus Comorbid Post-COVID-19 ConditionRecruitingNCT07197138Not applicable
- A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)RecruitingNCT07196501Phase 3
- Virtual Reality-Enhanced Behavioral Activation for Older Adults With DepressionRecruitingNCT07188623Not applicable
- Pharmacokinetics, Safety, Tolerability and Efficacy of a Subcutaneous Long-Acting Injection of Cariprazine (Cariprazine Depot) in Subjects Eligible for Treatment With Oral CariprazineRecruitingNCT07185815Phase 1/2
- An Empirical Study on the Mechanisms of Biopsychosocial Functional Improvement in Patients With Major Depressive Disorder Through Nature-Based Tourism ActivitiesRecruitingNCT07180342Not applicable
- Internet-Based Cognitive Behavioral Therapy With Treatment as Usual for Generalized Anxiety Disorder and Major Depressive Disorder in Taiwan (ICBT-TW)Not yet recruitingNCT07177365Not applicable
- Remote Evaluation and Alerting for Collaborative Health (REACH) in DepressionRecruitingNCT07174557Not applicable
- An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)Enrolling by invitationNCT07161700Phase 2
- Brain Functional Connectivity Mechanism of Cognitive Flexibility Impairment and rTMS Intervention in Major Depressive DisorderNot yet recruitingNCT07161492Not applicable
- Neurofeedback to Treat Depression - 2RecruitingNCT07159061Not applicable
- Virtual Reality-Augmented At-Home tDCS for Major DepressionEnrolling by invitationNCT07146269Not applicable
- rTMS for Youth Inpatients With DepressionRecruitingNCT07140575Not applicable
- Pattern Separation in Major Depressive DisorderRecruitingNCT07139834Phase 1
- Understanding the Role of the Kappa Opioid Receptor in Ketamine's Attenuation of Suicidal ThoughtsNot yet recruitingNCT07139106Phase 4
- Does Semaglutide Improve Depressive Symptoms in Patients With Major Depressive Disorder and Overweight or ObesityRecruitingNCT07136714Phase 4
- Efficacy of Chronotherapeutic Combination for Major Depressive Episode With InsomniaRecruitingNCT07120880Phase 3
- Accelerated TMS for Treatment-Resistant ECTRecruitingNCT07115628Not applicable
- A Phase 2 Study of Zelquistinel or Placebo for the Reduction of Symptoms of Major Depressive DisorderRecruitingNCT07115329Phase 2
- Magnetic Resonance-Guided Focused Ultrasound Bilateral Capsulotomy for Refractory Anorexia Nervosa With Comorbid Obsessive Compulsive Disorder or Major Depressive DisorderRecruitingNCT07113665Phase 1