Depressive Disorder, Major: all 2,805 studies
Page 3 of 29. Open to participants first (565), then studies with results posted, then the rest; newest registration first within each.
- Feasibility of Home-Based Intermittent 60Hz Light Therapy for Major Depressive Disorder (MDD)RecruitingNCT07111390Not applicable
- Disposition Kinetics of Dolutegravir Among People Living With HIV With Major Depression in NigeriaNot yet recruitingNCT07110831Phase 4
- Evaluating Conversational Artificial Intelligence for Depression ManagementRecruitingNCT07105397Not applicable
- A Study to Evaluate the Effectiveness of Valbenazine in Adult Participants With Tardive Dyskinesia (TD) Who Remain Symptomatic While Receiving or After Stopping a Vesicular Monoamine Transporter 2 (VMAT2) InhibitorRecruitingNCT07105111Phase 4
- PET Imaging Using the Tracer [18F]VAT to Assess the Antidepressant Effect of Nicotine.RecruitingNCT07095205Phase 4
- Neuroimaging Markers of Midlife Depression and Cognitive Behavioural Therapy (CBT)Not yet recruitingNCT07091643Not applicable
- Ketamine Augmentation of ECT in Treatment-Resistant DepressionRecruitingNCT07088380Phase 3
- Exploring the Role of the Prefrontal Cortex in Decision-MakingRecruitingNCT07080489Not applicable
- The Role of mGluR5 in CBT-IRecruitingNCT07076342Phase 4
- A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)RecruitingNCT07065240Phase 2
- The Motor Activity - Subjective Energy (MASE) ProjectRecruitingNCT07059234Not applicable
- Imaging- vs. Scalp-Targeted Accelerated TMS for Depression: The Number Needed to Scan TrialNot yet recruitingNCT07043738Not applicable
- EEG-based Neurofeedback to Improve Emotion Regulation in Major Depressive Disorder: A Randomized Clinical TrialRecruitingNCT07041073Not applicable
- Theta-Burst Stimulation to Treat DepressionRecruitingNCT07033780Phase 1
- Efficacy of kTMP, a Novel Non-invasive Brain Stimulation Method, for the Treatment of AnhedoniaNot yet recruitingNCT07032428Not applicable
- Validation of a Composite Medical Device Using a Blood Biomarker-based Algorithm and MDQ for the Diagnosis of Bipolar DisorderRecruitingNCT07031817Not applicable
- Mindful Self-compassion for Anxiety and Depression: Impact of Delivery MethodRecruitingNCT07028216Not applicable
- Accelerated Intermittent Theta Burst Stimulation for Adolescent and Young Adult Depression With Elevated Suicide RiskRecruitingNCT07025720Not applicable
- Moving on After Breast Cancer Trial for Depressed Breast Cancer Survivors in PakistanRecruitingNCT07015944Not applicable
- Assessment of Whether Telehealth Family Psychoeducation for Major Depressive Disorder is DoableNot yet recruitingNCT07014241Not applicable
- Switching Medication and Augmentation Strategies for SSRI-Resistant Adolescent Depression（SMART-I)Not yet recruitingNCT07011693Phase 4
- Lifestyle Interventions to Prevent Cognitive Deficits in Subjects With Depressive Symptoms: From Mechanisms to Clinical PracticeRecruitingNCT07009223Not applicable
- JAK Signaling in DepressionRecruitingNCT07003997Phase 2
- Metabolic Profiling of Esketamine Treatment in Depressive DisorderRecruitingNCT07002684
- Implementation of a Multiple Intervention to Promote Healthy Lifestyles in Patients With DepressionNot yet recruitingNCT06990035Not applicable
- Physical Therapy for Depression Quality of Life (Pilot Study Protocol)RecruitingNCT06983405Not applicable
- Self Neuro-modulation Therapy for Major Depressive Disorder (MDD) With AnhedoniaRecruitingNCT06982820Not applicable
- Behavioural Development, Long-term Outcomes and Opportunities to Optimize Youth Mental Health TrajectoriesRecruitingNCT06978452
- Rapid Antidepressant Dynamics in Acute Neuromodulation TreatmentsRecruitingNCT06976840Not applicable
- Home-Based tDCS Treatment Of Major Depressive DisorderRecruitingNCT06976697Not applicable
- Home-Based tDCS for Depression in BPDRecruitingNCT06972368Not applicable
- Accelerated TMS for Perinatal DepressionRecruitingNCT06968390Not applicable
- Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)RecruitingNCT06966401Phase 3
- NBI-1065845-MDD3026: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)RecruitingNCT06963021Phase 3
- A Trial of Dextromethorphan and Bupropion Sustained-Release Tablets in Patients With Major Depressive DisorderRecruitingNCT06958692Phase 3
- Mental Health and PrePNot yet recruitingNCT06944691Not applicable
- Maintenance rTMS for Depression (Maitr-De)RecruitingNCT06938841Not applicable
- Antidepressant Response of DMT Masked With PropofolRecruitingNCT06927076Not applicable
- Clinical Efficacy, Safety, and Applicability of Home-based Bright Light Therapy in Outpatient Adolescents With Major Depressive DisorderRecruitingNCT06913309Not applicable
- NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)RecruitingNCT06911112Phase 3
- Efficacy and Mechanism of Transcranial Temporal Interference Stimulation (tTIS) in the Treatment of Adolescent DepressionNot yet recruitingNCT06902064Not applicable
- Enhancing Veteran-Clinical Collaboration in VA PRRCsRecruitingNCT06898879Not applicable
- Identifying Cerebral Hemodynamic Patterns in Mood Disorders and Mild Cognitive Impairment: A Functional Near-Infrared Spectroscopy (fNIRS) StudyRecruitingNCT06897670
- COpenhagen Magnetic Personalized Accelerated Brain Circuit Therapy for Treatment Resistant DepressionRecruitingNCT06895863Not applicable
- A Randomized Control Trial of Enhanced Cognitive Behavioural Group Therapy for Older Adults with Depression: Efficacy Across Older Age-GroupsNot yet recruitingNCT06894641Not applicable
- Understanding and Treating Suicidal Ideation With KetamineRecruitingNCT06891300Phase 2/3
- Mindfulness-Based Therapy for Serious Mental IllnessEnrolling by invitationNCT06880796Not applicable
- Designing and Pilot Testing a Just-in-time Adaptive Intervention (JITAI) for Adolescent Depression Treatment in Primary CareNot yet recruitingNCT06875726Not applicable
- Roflumilast as an Adjunct to Antidepressants in Major Depressive Disorder PatientsRecruitingNCT06860958Phase 3
- Linking Affective Dynamics in Response to Daily Stress to Peripheral Vascular Function in Working Age AdultsRecruitingNCT06860724Not applicable
- Validation of EmoDTx as a Digital Endpoint for Mood Monitoring in Adult Patients Suffering From Unipolar DepressionRecruitingNCT06860165
- Orexin Antagonism for Suicide Risk: A Proof-of-Concept Clinical TrialRecruitingNCT06854224Phase 2
- Mindfulness-Based Cognitive Therapy (MBCT) for the Prevention of Depression Relapse or Recurrence Using VideoconferenceRecruitingNCT06832605Not applicable
- Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive DisorderRecruitingNCT06830044Phase 3
- The Research of Ammoxetine Hydrochloride Enteric-coated Tablets in Subjects With DepressionNot yet recruitingNCT06827431Phase 3
- The Efficacy and Safety of Task-state-based Temporal Interference Stimulation (TI) in the Treatment of Patients With DepressionNot yet recruitingNCT06826469Not applicable
- Sleep TMS for DepressionRecruitingNCT06824415Not applicable
- Investigating the Impacts of Early Life Experience on the Brain & BehaviourRecruitingNCT06823492
- Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric InterventionsEnrolling by invitationNCT06823024
- Investigating the Brain's Physiological Responses in Depression and Autism, Using Transcranial Magnetic Stimulation and ElectroencephalographyEnrolling by invitationNCT06821646
- A Mechanistic Study to Assess a Single Dose of CYB003 in Participants With Depression and AnxietyRecruitingNCT06820723Phase 2
- Stress Dynamics and Familial Risk for Depression in Female AdolescentsRecruitingNCT06816329Not applicable
- Baby Swim As an Intervention for Depressive Symptoms and Lacking Attachment During the Postpartum PeriodRecruitingNCT06807801Not applicable
- Intermittent Fasting for Inflammation and Depression in Spinal Cord InjuryNot yet recruitingNCT06807528Not applicable
- LHC-CIDI-5 in Hong KongRecruitingNCT06804525
- Evaluating the Effectiveness and Acceptability of a GPT-4o and RAG-Based Voice Chatbot for Depression Screening Using PHQ-9Enrolling by invitationNCT06801925
- Modulating Spinal Interoceptive Pathways to Evaluate Their Role and Therapeutic Potential in MDD Symptomatic DomainsRecruitingNCT06795451Phase 1/2
- A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderRecruitingNCT06793397Phase 3
- Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of KetamineRecruitingNCT06788249Early Phase 1
- Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)RecruitingNCT06786624Phase 3
- Psilocybin Therapy for Psychological Distress in Palliative PatientsRecruitingNCT06782724Phase 2
- Validating the On-line Creyos Cognitive Assessment Platform in Older Adults With Major Depressive Disorder or Mild Cognitive ImpairmentRecruitingNCT06780917
- Feasibility Trial of Exercise as a Priming Strategy for rTMS Treatment in Difficult-to-Treat DepressionRecruitingNCT06773949Not applicable
- Internet-based Support for Adjustment to Prostate CancerRecruitingNCT06766526Not applicable
- Pharmacogenomics of Selective Serotonin Reuptake Inhibitor (SSRI)-Induced Behavioural ActivationRecruitingNCT06763081
- A Randomized, Double-blind, Placebo-controlled, Multicenter Clinical Study on the Treatment of Depression with Jieyu Chufan CapsulesNot yet recruitingNCT06749470Phase 4
- An Individual-specific Synchrony SignatureRecruitingNCT06749392Not applicable
- Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic ProfilingNot yet recruitingNCT06748950Not applicable
- Predictors of Relapse in Major Depressive Disorder (PERFORM-D)RecruitingNCT06746155
- Impact of Behavioral Activation on Depression and Quality of Life in Patients with Colon CancerNot yet recruitingNCT06745700Not applicable
- Association of Beta Blocker Use with Depressive OutcomesNot yet recruitingNCT06743633
- Prevalence and Severity of Depression in Coronary Artery Disease PatientsRecruitingNCT06740396
- Biomarkers/Biotypes, Course of Early Psychosis and Specialty ServicesRecruitingNCT06740383
- Social Cognition, Memory, and Executive Functions in Bipolar Disorder and Major Depressive DisorderRecruitingNCT06740331Not applicable
- Study of Sleep Inertia in Major Depressive Disorder by the Psychomotor Vigilance TaskRecruitingNCT06732284
- Digital Interventions for Adults with Treatment-Resistant Depression: a Pilot StudyRecruitingNCT06732089
- Development and Application of Precision Treatment Strategies for Common Mental DisordersRecruitingNCT06729541Not applicable
- Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning DeficitsRecruitingNCT06728774Not applicable
- Efficacy and Safety of DTMS in Adolescent Major Depressive DisorderRecruitingNCT06728280Not applicable
- Transdiagnostic Internet-delivered Intervention for Adolescents With Anxiety and DepressionRecruitingNCT06724666Not applicable
- Mood And Kids diEt (MAKE-It) Pilot TrialRecruitingNCT06716034Not applicable
- Non-invasive Brain Stimulation in Subjects with Major Depressive DisorderNot yet recruitingNCT06714643Not applicable
- Sedation and Guided Education for Depression StudyNot yet recruitingNCT06705270Not applicable
- Taking Action for College StudentsRecruitingNCT06700902Not applicable
- Stony Brook Medicine Anti-Inflammatory TrialNot yet recruitingNCT06699966Phase 4
- Efficacy of Statins Among Major Depressive DisorderRecruitingNCT06698666Phase 3
- Neurobehavioral Therapy For Epilepsy And Major Depressive DisorderRecruitingNCT06695767Not applicable
- Assessment of the Efficacy and Safety of Fecal Microbiota Transplantation (FMT) in Patients With Major Depressive DisorderRecruitingNCT06692361Not applicable
- A Mobile Health Intervention to Improve Psychosocial Functioning in Veterans With Posttraumatic Stress Disorder and Depression SymptomsNot yet recruitingNCT06689787Not applicable
- Reward-specific Changes of the Chemical Messenger Dopamine in the Brain of Healthy and Depressed PeopleRecruitingNCT06675851Phase 4