Conjunctivitis, Allergic clinical trials
The registry lists 210 studies for Conjunctivitis, Allergic across more than 10 countries. 18 are recruiting or about to start. 173 of them are mainly about Conjunctivitis, Allergic (how this is decided). Per ClinicalTrials.gov, last updated 2026-11-09.
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Who runs them
Alcon Research (21) · Bausch & Lomb Incorporated (17) · Vistakon Pharmaceuticals (9) · ORA, Inc. (9) · Allergan (9) · Aldeyra Therapeutics, Inc. (7) · Regeneron Pharmaceuticals (6) · Aciex Therapeutics, Inc. (6)
What is being tested here
Drugs under test in Conjunctivitis, Allergic studies, those with the most open studies first. Medicines only given beside them are not counted. How drugs are counted
| Drug | Open | Phase 3 | All |
|---|---|---|---|
| TL-925 | 3 | 0 | 4 |
| Tacrolimus | 1 | 3 | 7 |
| Probiotic | 1 | 0 | 1 |
| Cenegermin | 1 | 1 | 1 |
| Olopatadine | 0 | 7 | 26 |
| Alcaftadine | 0 | 5 | 10 |
| Bepotastine besilate | 0 | 3 | 7 |
| Reproxalap | 0 | 3 | 6 |
| Ketotifen | 0 | 3 | 5 |
| Loteprednol Etabonate | 0 | 0 | 5 |
Drug classes tested here Calcineurin inhibitors 1 open · Antihistamines 59 · Corticosteroids 10
Coming up
Studies recruiting or running, from their records. “Main data collection” ends at the primary completion date, the sponsor’s own estimate, which often moves.
All 6
- Nov 2026Daydrop® Triple Action for Allergic Eye Symptoms · i+Med S.Coop.
- Dec 2026Treatment of Ocular Surface Inflammations · Semmelweis University
- Jan 2027OJO-miR: microRNA Expression in Allergic Conjunctivitis. · Instituto de Oftalmología Fundación Conde de Valenciana
- Jan 2027A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal Keratoconjunctivitis · Laboratoires Thea
- Mar 2027Tacrolimus Eye Drops in Treatment of Vernal Keratoconjunctivitis · Sohag University
- Oct 2027Factors Determining Tolerance to Nasal Allergen Exposure With Advanced Age in a Subset of Birch Pollen Allergic Subjects · Sven Schneider, MD
Who these studies take
Of the 12 Conjunctivitis, Allergic studies recruiting now, 8 (67%) set no upper age limit and 4 (33%) stop at 75 or younger. 4 (33%) take children under 18. 0 (0%) are for women only and 0 (0%) for men only; 2 (17%) take healthy volunteers.
| Age | Women | Men |
|---|---|---|
| 10 | 4 (33%) | 4 (33%) |
| 18 | 11 (92%) | 11 (92%) |
| 30 | 11 (92%) | 11 (92%) |
| 40 | 11 (92%) | 11 (92%) |
| 50 | 10 (83%) | 10 (83%) |
| 65 | 9 (75%) | 9 (75%) |
| 75 | 8 (67%) | 8 (67%) |
| 85 | 8 (67%) | 8 (67%) |
Across all 210 studies, recruiting or not: 25% stop at 75 or younger and 24% at 65; 46% take children; 0% are for women only and 0% for men only; 20% take healthy volunteers. From each study’s registry entry; the criteria on its page decide.
How long Conjunctivitis, Allergic studies take
Of 21 phase 3 interventional studies under Conjunctivitis, Allergic, half reached primary completion within 6 months of starting, counting those still running.
| Start to primary completion | Every sponsor | Industry | Non-industry |
|---|---|---|---|
| Phase 3 | 6 mo4–14 · 21 studies | — | — |
Each figure is the month by which half the studies had reached primary completion, with the range in which the middle half did. Studies still running count until their last registry update; studies that stopped early are left out. Phase 1 includes early phase 1; observational means prospective or not stated, as retrospective and cross-sectional studies date a window of data rather than a study. How these figures are worked out
Studies
Recruiting first, then most recently updated. Showing 50 of 210. Browse all 210 → or search them.
- 3% Diquafosol Ophthalmic Solution for Active Moderate-to-Severe Vernal KeratoconjunctivitisRecruitingNCT06903884Phase 31 country
- A Study to Evaluate the Efficacy and Safety of Fel d 1 Monoclonal Antibodies in Adult and Pediatric Participants With Allergic Conjunctivitis Due to Cat AllergyRecruitingNCT07675811Phase 31 country
- Daydrop® Triple Action for Allergic Eye SymptomsRecruitingNCT07805759Not applicable1 country
- An Efficacy and Safety Study of Cenegermin Ophthalmic Solution Compared With Vehicle in the Treatment of PCEDRecruitingNCT07519902Phase 314 countries
- Investigating Nasal and Ocular Immune Response to Conjunctival Allergen ExposureRecruitingNCT078016251 country
- Treatment of Ocular Surface InflammationsRecruitingNCT077328551 country
- A Study to Identify and Characterize Adults and Pediatric Participants With Cat and/or Birch AllergyNot yet recruitingNCT07710846
- Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular SurfaceRecruitingNCT041987401 country
- A Study to Compare the Effectiveness and Safety of T1695 Versus Ciclosporin in Participants With Moderate to Severe Vernal KeratoconjunctivitisRecruitingNCT07169695Phase 21 country
- Kelulut Honey for Allergic Conjunctivitis and Dry Eye SymptomsRecruitingNCT07273747Not applicable1 country
- Evaluation of TL-925 for the Treatment of Seasonal Allergic ConjunctivitisRecruitingNCT07220408Phase 21 country
- Treg Effector Function and Th2/Treg Ratio in Allergic Conjunctivitis: Effect of Desensitization TherapyNot yet recruitingNCT071713071 country
- Tacrolimus Eye Drops in Treatment of Vernal KeratoconjunctivitisNot yet recruitingNCT07138742Not applicable
- Factors Determining Tolerance to Nasal Allergen Exposure With Advanced Age in a Subset of Birch Pollen Allergic SubjectsNot yet recruitingNCT064592191 country
- Efficacy and Safety of Oral Probiotics on Ocular Symptoms and Gut Microbiome of Children with Vernal KeratoconjunctivitisNot yet recruitingNCT06793514Phase 1
- Evaluation of TL-925 for the Treatment of Allergic ConjunctivitisRecruitingNCT06686472Phase 21 country
- The Role of Vitamin D in Corneal Epithelial Barrier Function, Ocular Microbiome, Ocular Inflammation, and Visual Acuity of Children With Allergic ConjunctivitisEnrolling by invitationNCT05839938Not applicable1 country
- A Study of TL-925 for the Treatment of Allergic ConjunctivitisRecruitingNCT06153342Phase 21 country
- Study of Bet v1 Antibodies Effect on Eye Allergy Symptoms in Adolescents and Adults With Birch Pollen AllergyTerminatedNCT07309432Phase 31 country
- The INVIGORATE 2 Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic ConjunctivitisCompletedNCT05234554Phase 31 country
- A Study to Demonstrate How Well REGN1908-1909 Works in Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Cat AllergyCompletedNCT06602726Phase 32 countries
- A Study to Demonstrate the Effect of REGN5713-5715 on Reducing Ocular Allergy Signs and Symptoms in Adult Participants With Birch Pollen AllergyCompletedNCT06602739Phase 32 countries
- OJO-miR: microRNA Expression in Allergic Conjunctivitis.Active, not recruitingNCT073854951 country
- The Effects of Ectoin® Allergy Nasal Spray and Ectoin® Allergy Eye Drops Compared to PlaceboCompletedNCT01471184Not applicable1 country
- Tyrosine Allergoid Paediatric and Adult StudyActive, not recruitingNCT051860251 country
- Safety and Efficacy of VSJ-110 in the Treatment of Allergic Conjunctivitis in Adults With a History of Ocular AllergiesCompletedNCT04622345Phase 21 country
- Documentation of Efficacy of Intralymphatic Allergen ImmunotherapyCompletedNCT05191186Phase 32 countries
- Clinical and Biological Evaluation of NAAGA Versus Azelastine Eye Drops in Allergic Subjects With Tear Film DysfunctionCompletedNCT06800274Phase 41 country
- Evaluation of the Safety and Pharmacokinetics of Brimonidine Tartrate 0.025%/Ketotifen Fumarate 0.035% Combination Ophthalmic SolutionCompletedNCT05815758Phase 31 country
- Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination in Adults With Seasonal Allergic ConjunctivitisCompletedNCT05591755Phase 31 country
- Topical rVA576 for Treatment of Atopic KeratoconjunctivitisTerminatedNCT04037891Phase 1/22 countries
- A Methodology Development Environmental Clinical Trial of Reproxalap in Subjects With Seasonal Allergic ConjunctivitisCompletedNCT03660878Phase 1/21 country
- Evaluation of Central Corneal Thickness in Patients With Vernal Keratoconjunctivitis Using Topical SteroidsActive, not recruitingNCT069137901 country
- A Methodology Development Clinical Trial of Reproxalap in Subjects With Seasonal Allergic Conjunctivitis Using the Environmental Exposure ChamberCompletedNCT03709121Phase 1/21 country
- Evaluation of Brimonidine Tartrate/Ketotifen Fumarate Combination for the Treatment of Allergic ConjunctivitisCompletedNCT05579730Phase 31 country
- ALLEVIATE Trial - A Phase 3 Trial in Subjects With Allergic ConjunctivitisCompletedNCT03494504Phase 31 country
- The INVIGORATE Trial: A Clinical Trial to Assess the Efficacy and Safety of Subjects With Seasonal Allergic Conjunctivitis.CompletedNCT04207736Phase 31 country
- A Study of the Effects of Desloratadine on Conjunctival Allergen Challenge-induced Ocular Signs and Symptoms (Study P04209)CompletedNCT00311844Phase 4
- A Study of MDI-1228_mesylate Ophthalmic Solution in Healthy AdultsCompletedNCT05969236Phase 11 country
- A Study Of TL-925 For The Treatment of ACCompletedNCT06293820Phase 21 country
- Dietary Choice for the Management of Cow's Milk Allergy Influences Other Allergic ManifestationsCompletedNCT038619101 country
- A Study to Examine the Efficacy and Safety of Anti-Fel d 1 Antibodies Injections in Cat-allergic Adolescent and Adult Patients With Allergic Rhinitis Who Live With a CatTerminatedNCT04981717Phase 36 countries
- Ketotifen/Naphazoline Ophthalmic Solution in the Conjunctival Allergen Challenge Model of Allergic Conjunctivitis.CompletedNCT00769886Phase 31 country
- A Study to Evaluate the Efficacy and Safety of Epinastine Hydrochloride Eye Drops in the Treatment of Chinese Seasonal Allergic Conjunctivitis PatientsCompletedNCT06212973Phase 31 country
- A Safety and Activity Study of NS2 in Subjects With Allergic ConjunctivitisCompletedNCT02578914Phase 21 country
- Food-specific IgG4-guided Elimination Diets Improve Allergy Symptoms in ChildrenCompletedNCT060630441 country
- Airway Immune Response to Allergens (Use Lay Language Here)Active, not recruitingNCT04619017Phase 11 country
- Evaluation of the Safety and Efficacy of Ketotifen 4.0% Patch as Compared to Placebo Patch, Olopatadine 0.2% Ophthalmic Solution, and Artificial Tears in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic ConjunctivitisCompletedNCT00836485Phase 21 country
- A Single-Center Evaluation of the Relative Efficacy of EM-100 Compared to Zaditor® (Ketotifen Fumarate Ophthalmic Solution 0.035%) and VehicleCompletedNCT03489941Phase 31 country
- PMCF Study to Evaluate Performance and Safety of "Xanoftal Next"CompletedNCT05829499Not applicable1 country